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The map label for this gene is luxQ [H]

Identifier: 78048722

GI number: 78048722

Start: 3590574

End: 3594176

Strand: Reverse

Name: luxQ [H]

Synonym: XCV3166

Alternate gene names: 78048722

Gene position: 3594176-3590574 (Counterclockwise)

Preceding gene: 78048723

Following gene: 78048721

Centisome position: 69.41

GC content: 63.06

Gene sequence:

>3603_bases
ATGCTGCTACCACCACAACACCCCAGTCGTCGCATGCCGCTGAAAGCCTTGATGACGCGGGCTTTATTACTGCTTTGCCT
GGCCGTCGTGTCAGGCTGGCCGAGTCTTACGCTGGCCGGCGTGCCGGTACTGCCGCAGCCGCGGCAGCTGACCGTGGCCG
ACGGGCTGCCATCCAACGTGGTGTACGGCTTCGATGAGGATGCCAATGGATATTTGTGGCTGGCCAGCAGCGATGGGTTA
GCGCGTTACGACGGGCGAAACTTCCGTATCTGGCGCATCGAAGACGGTTTGCGCGACAACCAGATCTGGGCGGTTCACGT
CGACAAGCGCAACCGGGTCTGGATCGGGACCGGCATGGCAGGCCTTGCGATGCTGGACCCCGCACGCCATCAATTCACTT
TCTATGATGGTGCGCGCTATCCGGAACTTCGCGGCGCTGCGATCTGGAACATCAAGTCTACCGACGACGGCAGCATATGG
TTCGGCACTGAAATGAGTGGGCTATACCGGCTGCGGCCGGATGGTTCGCTGGAGCATTTCGCACATCGTGTCGACGATCC
GCGCAGCTTGCCCGACAACGCGATCTATCGGCTTGATGTCGATACCCGCGGCACACTTTGGATCGGTACCGCCGATGGTG
CTGCGCATTGGACGGGTAATGACTTCGAGCGGCAGGCATTTCCGGATGGCACCGCACAGATCATCACCCGGCTAACTGCC
GATGCCGATGGCAGCATCTGGATCGGGACCAGCGACGACAAGCTGTTTCGGCGCGATCCAAGTGGTCATCTCAGTCCGCA
CCGTTGGCAGGCACCTGCAGAATATCCGGTATTGGGCGTGTTGTTGCGCGACCAGGACGGCAGCTATTGGCTGGACACCC
TGGCCGGCCTAGGCCATACGACTGGTGCGGAGGTGCGCAATGTCCCCCTGTACAGTCTGTCTGCGCACGGGCGTATCCGT
CCCAACTGGGAATCGGCATATCAGGATCGCGAGGGCGGTGTATGGTTTGCCAGCCCCAACGGCGGGCTCTGGCATCTCCC
CTCGAACTGGCATCGTTTCGCGGTAGTTTTCAACTACATGGACGACGGTGGCCAAGGTGGCAACCTGGCGATCCAGGGCA
CTGCAAAATCGCGCGATGGTCGGATGTGGTTGGTGGGCACCTCGGGCGTGCTCGAACGCGTAGATCCTGCCACCGGCAAA
ATCGAGCGTGTATTGCCCACCCTGGGGTCTGCCAGCTGGTCCAATAGCGTGCTGGAGGATCGCAAGGGTAACGTCTGGGT
CGGGCAGTTTGCCGAGCTGGTGCGCTTTGATCCCGCTACTGGCCAGGTGCAGCACTGGAAGGCTGCAGCAAGCGGCTCGG
ACGCGGCTGCACAGGACGCGACACTGGACGCTTCCTTGGAAGCGCTGCAGCAGACCGCCGATGGTCACATCTGGGTCCAT
GCCACGCTTGGGCTACAAGAGCGGGACGAACAAGGTCGCTTGCTGCGCACCATGTTGCGCGGGACCCACGGCCTTGCAGC
AGATCTGGTGGTTTACGACCTGCAGGCTGGGCCGGACGGAGCGCTCTGGCTGGCCAGTAATCGTGGTCTGCAGCGCTGGA
ACGCGTCGGTTGCGCGCTTCGAGCGCATTGCCGGCGCACCCGACGAACCTATCTTCACTTTTCGCTTCAGCGACAACCAG
ATCGCCTGGTTTGCCGGGCTAGGGAAGCTCCGCCGCTATTTGTGGAAGAACGGCACCCTGCAACATCTAGATACAGTGGG
CCCCGAGCAGAACTTCCCTGCGCTTGCGCCACAGGGACTGGTGATCGACCACGACGGTGTTGCCTGGATGTCCAGTATGC
GTGGCCTGATTCGCGTTGACCCGGCCACGCGGGGCGTGCGCGTGTTCGGGGTTCATGACGGCCTGCCCAATCCGCAATTC
GTTGCGCGTTCTTTGGTGCAATCGTCAAAGGGCATGATCGTCGGCGCGACGCCGGATGGGCTGGTGATCTTCGATCCTGC
CGAACTCAAGCCGAATGATCATCGGGTGCCGTTGGTGATCGAACGTGTGGGTCTACGTCGCGGCGAGAGCGGGCTGGATC
TGAGTCATGTCACGCCTTTGGTCATGCAGGACGGCGACCGCGACTTGCATATCGTCGCCCGCCTGCTCAGCTTCGCCGAC
TCCGAATCCAATAGCTACCGCTTCCGCCTGAGCGGCTACGACCCGGACTGGATCGATGTCGGGCCCAGTGGCGAGCGCCT
GTTTTCGCGTCTGCCTTCAGGCCGTTACACGCTGGAAGTGCAGGGGCGCACTGCAGACGGGATCTGGTCGGCGAGCCAGA
CCTTGCGTTTTCAGGTGTTGCCGCCATGGTGGCTGTCGCCGTGGGGCTTGAGCCTGCTGGCCCTGCTGACCGTGTGCGTG
ATTGCTGCAGCTATCTTGTTGTACCGCCGTCGGTTGCGTCGCTTGAATGCCTGGCAGCTTGCGGTGCACAAACAGGAAGT
GGCCGAGCAGGCGTCCCTGGCCAAGACGCGTTTTTTGGCGACCCTGGGCCACGAAGTGCGTACGCCGATGACGGGCGTCT
TGGGCATGAGTGAGCTGCTGCTCAAGACTTCGCTGGATCTCAAACAGCGCAGTTACACCGAGTCGATCCGCCGCGCAGGC
GCGCATTTGTTGCGGCTGGTCAACGATGCGCTGGATCTTGCGCGCATCGAATCCGGGCGGCTGGAGCTGGATGTGGAGCC
GTTTTCGGTGCGTCAGCTGGTGGCCGAAGTGGAGGCGTTGATGGCGCCGCTGGCGCAGGAGCGTGGCCTGCGCTTCAGCC
TGGAGATCGGGCTGCTCGGCGATATCACTGCCAGTGGCGATTGCACCCGCATCCGGCAGATCCTGCTCAACCTGCTCAAT
AACGCGATCAAATTCACCGAGCGCGGCGTGGTCGGGTTGAAGTTGACCACGCTCGGTTCCTATCAAGGCCTGCGCTTTGA
AGTGGCCGACACGGGGCCGGGCATCAACGCCGAACAGAAGGCGCGGCTGTTCCAGCGCTTCGAGCAGGGCGATGGTGCCA
GAACCACCTCGCGCTACGGCGGCAGTGGTCTGGGCTTGGCGATCTGCCAGGAGCTGGCAATCGCCATGGGCGGGCAGATC
GAGGTGATCAGCCGACTCGGTGCGGGGACGCGCTTCGTGGTGGATCTGCCGCTGCGCTGGGTGGCTTCCAACGCCGCGCT
CGGTGGCGAGACCGCGCATGCCGAGACGGCTGTCGAGCCGCAGCGCATCCTGCTGGTGGAAGACGACCCGACCATCGCCG
AGGTCATCGTCGGCCTGCTGCAAGCGCAAGGGCATTCGGTCGTGCATGCCCCGCATGGCCTGGCGGCGCTGACCGAAGCG
GCCGACAACACGTTCGATCTGGCATTGCTGGATCTGGACCTGCCCGGGCTGGATGGTTTTGCGCTGGCGCGGCAGTTGCG
CGTCTTCGGCTACGACATGCCGTTGATCGCCGTGACTGCACGCGCCGACGAGGTCGCCGAACCAAGCGCGCAGGAAGCCG
GCTTCGACAGCTTCCTACGCAAGCCGCTCACTGGCGACATGCTGGCCGCCACCATTGCCGAAGCGTTACGCAGCAAGCGC
TGA

Upstream 100 bases:

>100_bases
TACGATGCCTGCCTGCTGTAACGATCACCGTTGGCGCGCTTCTGTGTGTTGCCAGCATCAGGCAAGGTCCGCACTATGCG
TGCAAAGGACACGCGAGCGC

Downstream 100 bases:

>100_bases
CAAGCGCTGCGGATGCTCTGTCACCGGAGCAGGCATCCAAGTATCACGCGGCGTGTTCGTCCGCTCTTGGGCCGCTCGAA
CAGCGATGCGGGTCGCGATG

Product: two-component system sensor histidine kinase-response regulator hybrid protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 1200; Mature: 1200

Protein sequence:

>1200_residues
MLLPPQHPSRRMPLKALMTRALLLLCLAVVSGWPSLTLAGVPVLPQPRQLTVADGLPSNVVYGFDEDANGYLWLASSDGL
ARYDGRNFRIWRIEDGLRDNQIWAVHVDKRNRVWIGTGMAGLAMLDPARHQFTFYDGARYPELRGAAIWNIKSTDDGSIW
FGTEMSGLYRLRPDGSLEHFAHRVDDPRSLPDNAIYRLDVDTRGTLWIGTADGAAHWTGNDFERQAFPDGTAQIITRLTA
DADGSIWIGTSDDKLFRRDPSGHLSPHRWQAPAEYPVLGVLLRDQDGSYWLDTLAGLGHTTGAEVRNVPLYSLSAHGRIR
PNWESAYQDREGGVWFASPNGGLWHLPSNWHRFAVVFNYMDDGGQGGNLAIQGTAKSRDGRMWLVGTSGVLERVDPATGK
IERVLPTLGSASWSNSVLEDRKGNVWVGQFAELVRFDPATGQVQHWKAAASGSDAAAQDATLDASLEALQQTADGHIWVH
ATLGLQERDEQGRLLRTMLRGTHGLAADLVVYDLQAGPDGALWLASNRGLQRWNASVARFERIAGAPDEPIFTFRFSDNQ
IAWFAGLGKLRRYLWKNGTLQHLDTVGPEQNFPALAPQGLVIDHDGVAWMSSMRGLIRVDPATRGVRVFGVHDGLPNPQF
VARSLVQSSKGMIVGATPDGLVIFDPAELKPNDHRVPLVIERVGLRRGESGLDLSHVTPLVMQDGDRDLHIVARLLSFAD
SESNSYRFRLSGYDPDWIDVGPSGERLFSRLPSGRYTLEVQGRTADGIWSASQTLRFQVLPPWWLSPWGLSLLALLTVCV
IAAAILLYRRRLRRLNAWQLAVHKQEVAEQASLAKTRFLATLGHEVRTPMTGVLGMSELLLKTSLDLKQRSYTESIRRAG
AHLLRLVNDALDLARIESGRLELDVEPFSVRQLVAEVEALMAPLAQERGLRFSLEIGLLGDITASGDCTRIRQILLNLLN
NAIKFTERGVVGLKLTTLGSYQGLRFEVADTGPGINAEQKARLFQRFEQGDGARTTSRYGGSGLGLAICQELAIAMGGQI
EVISRLGAGTRFVVDLPLRWVASNAALGGETAHAETAVEPQRILLVEDDPTIAEVIVGLLQAQGHSVVHAPHGLAALTEA
ADNTFDLALLDLDLPGLDGFALARQLRVFGYDMPLIAVTARADEVAEPSAQEAGFDSFLRKPLTGDMLAATIAEALRSKR

Sequences:

>Translated_1200_residues
MLLPPQHPSRRMPLKALMTRALLLLCLAVVSGWPSLTLAGVPVLPQPRQLTVADGLPSNVVYGFDEDANGYLWLASSDGL
ARYDGRNFRIWRIEDGLRDNQIWAVHVDKRNRVWIGTGMAGLAMLDPARHQFTFYDGARYPELRGAAIWNIKSTDDGSIW
FGTEMSGLYRLRPDGSLEHFAHRVDDPRSLPDNAIYRLDVDTRGTLWIGTADGAAHWTGNDFERQAFPDGTAQIITRLTA
DADGSIWIGTSDDKLFRRDPSGHLSPHRWQAPAEYPVLGVLLRDQDGSYWLDTLAGLGHTTGAEVRNVPLYSLSAHGRIR
PNWESAYQDREGGVWFASPNGGLWHLPSNWHRFAVVFNYMDDGGQGGNLAIQGTAKSRDGRMWLVGTSGVLERVDPATGK
IERVLPTLGSASWSNSVLEDRKGNVWVGQFAELVRFDPATGQVQHWKAAASGSDAAAQDATLDASLEALQQTADGHIWVH
ATLGLQERDEQGRLLRTMLRGTHGLAADLVVYDLQAGPDGALWLASNRGLQRWNASVARFERIAGAPDEPIFTFRFSDNQ
IAWFAGLGKLRRYLWKNGTLQHLDTVGPEQNFPALAPQGLVIDHDGVAWMSSMRGLIRVDPATRGVRVFGVHDGLPNPQF
VARSLVQSSKGMIVGATPDGLVIFDPAELKPNDHRVPLVIERVGLRRGESGLDLSHVTPLVMQDGDRDLHIVARLLSFAD
SESNSYRFRLSGYDPDWIDVGPSGERLFSRLPSGRYTLEVQGRTADGIWSASQTLRFQVLPPWWLSPWGLSLLALLTVCV
IAAAILLYRRRLRRLNAWQLAVHKQEVAEQASLAKTRFLATLGHEVRTPMTGVLGMSELLLKTSLDLKQRSYTESIRRAG
AHLLRLVNDALDLARIESGRLELDVEPFSVRQLVAEVEALMAPLAQERGLRFSLEIGLLGDITASGDCTRIRQILLNLLN
NAIKFTERGVVGLKLTTLGSYQGLRFEVADTGPGINAEQKARLFQRFEQGDGARTTSRYGGSGLGLAICQELAIAMGGQI
EVISRLGAGTRFVVDLPLRWVASNAALGGETAHAETAVEPQRILLVEDDPTIAEVIVGLLQAQGHSVVHAPHGLAALTEA
ADNTFDLALLDLDLPGLDGFALARQLRVFGYDMPLIAVTARADEVAEPSAQEAGFDSFLRKPLTGDMLAATIAEALRSKR
>Mature_1200_residues
MLLPPQHPSRRMPLKALMTRALLLLCLAVVSGWPSLTLAGVPVLPQPRQLTVADGLPSNVVYGFDEDANGYLWLASSDGL
ARYDGRNFRIWRIEDGLRDNQIWAVHVDKRNRVWIGTGMAGLAMLDPARHQFTFYDGARYPELRGAAIWNIKSTDDGSIW
FGTEMSGLYRLRPDGSLEHFAHRVDDPRSLPDNAIYRLDVDTRGTLWIGTADGAAHWTGNDFERQAFPDGTAQIITRLTA
DADGSIWIGTSDDKLFRRDPSGHLSPHRWQAPAEYPVLGVLLRDQDGSYWLDTLAGLGHTTGAEVRNVPLYSLSAHGRIR
PNWESAYQDREGGVWFASPNGGLWHLPSNWHRFAVVFNYMDDGGQGGNLAIQGTAKSRDGRMWLVGTSGVLERVDPATGK
IERVLPTLGSASWSNSVLEDRKGNVWVGQFAELVRFDPATGQVQHWKAAASGSDAAAQDATLDASLEALQQTADGHIWVH
ATLGLQERDEQGRLLRTMLRGTHGLAADLVVYDLQAGPDGALWLASNRGLQRWNASVARFERIAGAPDEPIFTFRFSDNQ
IAWFAGLGKLRRYLWKNGTLQHLDTVGPEQNFPALAPQGLVIDHDGVAWMSSMRGLIRVDPATRGVRVFGVHDGLPNPQF
VARSLVQSSKGMIVGATPDGLVIFDPAELKPNDHRVPLVIERVGLRRGESGLDLSHVTPLVMQDGDRDLHIVARLLSFAD
SESNSYRFRLSGYDPDWIDVGPSGERLFSRLPSGRYTLEVQGRTADGIWSASQTLRFQVLPPWWLSPWGLSLLALLTVCV
IAAAILLYRRRLRRLNAWQLAVHKQEVAEQASLAKTRFLATLGHEVRTPMTGVLGMSELLLKTSLDLKQRSYTESIRRAG
AHLLRLVNDALDLARIESGRLELDVEPFSVRQLVAEVEALMAPLAQERGLRFSLEIGLLGDITASGDCTRIRQILLNLLN
NAIKFTERGVVGLKLTTLGSYQGLRFEVADTGPGINAEQKARLFQRFEQGDGARTTSRYGGSGLGLAICQELAIAMGGQI
EVISRLGAGTRFVVDLPLRWVASNAALGGETAHAETAVEPQRILLVEDDPTIAEVIVGLLQAQGHSVVHAPHGLAALTEA
ADNTFDLALLDLDLPGLDGFALARQLRVFGYDMPLIAVTARADEVAEPSAQEAGFDSFLRKPLTGDMLAATIAEALRSKR

Specific function: At low cell density, in absence of AI-2 (autoinducer 2), luxQ has a kinase activity and autophosphorylates on a histidine residue. The phosphoryl group is then transferred to an aspartate residue in the response regulator domain. The phosphoryl group is t

COG id: COG3292

COG function: function code T; Predicted periplasmic ligand-binding sensor domain

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=373, Percent_Identity=34.8525469168901, Blast_Score=188, Evalue=2e-48,
Organism=Escherichia coli, GI1788713, Length=385, Percent_Identity=31.4285714285714, Blast_Score=186, Evalue=1e-47,
Organism=Escherichia coli, GI87081816, Length=374, Percent_Identity=35.2941176470588, Blast_Score=177, Evalue=3e-45,
Organism=Escherichia coli, GI1789149, Length=379, Percent_Identity=32.4538258575198, Blast_Score=170, Evalue=4e-43,
Organism=Escherichia coli, GI145693157, Length=233, Percent_Identity=37.7682403433476, Blast_Score=148, Evalue=2e-36,
Organism=Escherichia coli, GI1786600, Length=250, Percent_Identity=31.2, Blast_Score=100, Evalue=5e-22,
Organism=Escherichia coli, GI1786912, Length=242, Percent_Identity=32.2314049586777, Blast_Score=100, Evalue=7e-22,
Organism=Escherichia coli, GI1786783, Length=243, Percent_Identity=31.2757201646091, Blast_Score=93, Evalue=9e-20,
Organism=Escherichia coli, GI1788393, Length=230, Percent_Identity=29.5652173913043, Blast_Score=92, Evalue=2e-19,
Organism=Escherichia coli, GI1788394, Length=116, Percent_Identity=35.3448275862069, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1790436, Length=272, Percent_Identity=27.2058823529412, Blast_Score=74, Evalue=4e-14,
Organism=Escherichia coli, GI1787894, Length=232, Percent_Identity=28.0172413793103, Blast_Score=73, Evalue=1e-13,
Organism=Escherichia coli, GI1789808, Length=210, Percent_Identity=30, Blast_Score=70, Evalue=7e-13,
Organism=Escherichia coli, GI1790860, Length=113, Percent_Identity=35.3982300884956, Blast_Score=69, Evalue=2e-12,
Organism=Escherichia coli, GI1790346, Length=231, Percent_Identity=27.7056277056277, Blast_Score=69, Evalue=2e-12,
Organism=Escherichia coli, GI1788549, Length=239, Percent_Identity=27.6150627615063, Blast_Score=68, Evalue=3e-12,
Organism=Escherichia coli, GI1788279, Length=230, Percent_Identity=27.3913043478261, Blast_Score=67, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6322044, Length=150, Percent_Identity=30.6666666666667, Blast_Score=75, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR015387
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789
- ProDom:   PD142495 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF09308 LuxQ-periplasm; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 131675; Mature: 131675

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLPPQHPSRRMPLKALMTRALLLLCLAVVSGWPSLTLAGVPVLPQPRQLTVADGLPSNV
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCEEEEECCCCCCE
VYGFDEDANGYLWLASSDGLARYDGRNFRIWRIEDGLRDNQIWAVHVDKRNRVWIGTGMA
EEECCCCCCCEEEEECCCCCEEECCCEEEEEEECCCCCCCCEEEEEECCCCEEEEECCCC
GLAMLDPARHQFTFYDGARYPELRGAAIWNIKSTDDGSIWFGTEMSGLYRLRPDGSLEHF
CHHHCCCCCCEEEEECCCCCCCCCCCEEEEEECCCCCCEEEECCCCCEEEECCCCCHHHH
AHRVDDPRSLPDNAIYRLDVDTRGTLWIGTADGAAHWTGNDFERQAFPDGTAQIITRLTA
HHHCCCCCCCCCCCEEEEEECCCCEEEEECCCCCCCCCCCCCCHHCCCCCHHHHHHHHHC
DADGSIWIGTSDDKLFRRDPSGHLSPHRWQAPAEYPVLGVLLRDQDGSYWLDTLAGLGHT
CCCCCEEEECCCCCCEECCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCHHHHHHCCCCC
TGAEVRNVPLYSLSAHGRIRPNWESAYQDREGGVWFASPNGGLWHLPSNWHRFAVVFNYM
CCCCCCCCCEEEECCCCCCCCCHHHHHCCCCCCEEEECCCCCEEECCCCCEEEEEEEEEC
DDGGQGGNLAIQGTAKSRDGRMWLVGTSGVLERVDPATGKIERVLPTLGSASWSNSVLED
CCCCCCCCEEEEECCCCCCCEEEEEECCHHHHHCCCCCCHHHHHHHHHCCCCCCCHHHHC
RKGNVWVGQFAELVRFDPATGQVQHWKAAASGSDAAAQDATLDASLEALQQTADGHIWVH
CCCCEEHHHHHHHHHCCCCCCCHHHHEECCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEE
ATLGLQERDEQGRLLRTMLRGTHGLAADLVVYDLQAGPDGALWLASNRGLQRWNASVARF
EEECCCCCCHHHHHHHHHHHCCCCCEEEEEEEEECCCCCCEEEEECCCCHHHHHHHHHHH
ERIAGAPDEPIFTFRFSDNQIAWFAGLGKLRRYLWKNGTLQHLDTVGPEQNFPALAPQGL
HHHCCCCCCCEEEEEECCCCEEEHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCCCCCE
VIDHDGVAWMSSMRGLIRVDPATRGVRVFGVHDGLPNPQFVARSLVQSSKGMIVGATPDG
EEECCCHHHHHHCCCEEEECCCCCCEEEEEECCCCCCHHHHHHHHHHCCCCEEEECCCCC
LVIFDPAELKPNDHRVPLVIERVGLRRGESGLDLSHVTPLVMQDGDRDLHIVARLLSFAD
EEEECCCCCCCCCCCCCEEEEECCCCCCCCCCCHHHCCCCEECCCCCHHHHHHHHHHHHC
SESNSYRFRLSGYDPDWIDVGPSGERLFSRLPSGRYTLEVQGRTADGIWSASQTLRFQVL
CCCCCEEEEECCCCCCCEECCCCHHHHHHHCCCCCEEEEECCCCCCCCCCCCCEEEEEEC
PPWWLSPWGLSLLALLTVCVIAAAILLYRRRLRRLNAWQLAVHKQEVAEQASLAKTRFLA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
TLGHEVRTPMTGVLGMSELLLKTSLDLKQRSYTESIRRAGAHLLRLVNDALDLARIESGR
HHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
LELDVEPFSVRQLVAEVEALMAPLAQERGLRFSLEIGLLGDITASGDCTRIRQILLNLLN
EEEECCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEECCCCCCCHHHHHHHHHHHHH
NAIKFTERGVVGLKLTTLGSYQGLRFEVADTGPGINAEQKARLFQRFEQGDGARTTSRYG
HHHHHHCCCEEEEEEEEECCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCC
GSGLGLAICQELAIAMGGQIEVISRLGAGTRFVVDLPLRWVASNAALGGETAHAETAVEP
CCCHHHHHHHHHHHHCCCCCHHHHHCCCCCEEEEECCHHHHHCCCCCCCCCCCCCCCCCC
QRILLVEDDPTIAEVIVGLLQAQGHSVVHAPHGLAALTEAADNTFDLALLDLDLPGLDGF
CEEEEEECCCCHHHHHHHHHHCCCCCEEECCCCHHHHHHHCCCCEEEEEEEECCCCCCHH
ALARQLRVFGYDMPLIAVTARADEVAEPSAQEAGFDSFLRKPLTGDMLAATIAEALRSKR
HHHHHHHHHCCCCCEEEEEECCHHHCCCCHHHCCHHHHHHCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLLPPQHPSRRMPLKALMTRALLLLCLAVVSGWPSLTLAGVPVLPQPRQLTVADGLPSNV
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCEEEEECCCCCCE
VYGFDEDANGYLWLASSDGLARYDGRNFRIWRIEDGLRDNQIWAVHVDKRNRVWIGTGMA
EEECCCCCCCEEEEECCCCCEEECCCEEEEEEECCCCCCCCEEEEEECCCCEEEEECCCC
GLAMLDPARHQFTFYDGARYPELRGAAIWNIKSTDDGSIWFGTEMSGLYRLRPDGSLEHF
CHHHCCCCCCEEEEECCCCCCCCCCCEEEEEECCCCCCEEEECCCCCEEEECCCCCHHHH
AHRVDDPRSLPDNAIYRLDVDTRGTLWIGTADGAAHWTGNDFERQAFPDGTAQIITRLTA
HHHCCCCCCCCCCCEEEEEECCCCEEEEECCCCCCCCCCCCCCHHCCCCCHHHHHHHHHC
DADGSIWIGTSDDKLFRRDPSGHLSPHRWQAPAEYPVLGVLLRDQDGSYWLDTLAGLGHT
CCCCCEEEECCCCCCEECCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCHHHHHHCCCCC
TGAEVRNVPLYSLSAHGRIRPNWESAYQDREGGVWFASPNGGLWHLPSNWHRFAVVFNYM
CCCCCCCCCEEEECCCCCCCCCHHHHHCCCCCCEEEECCCCCEEECCCCCEEEEEEEEEC
DDGGQGGNLAIQGTAKSRDGRMWLVGTSGVLERVDPATGKIERVLPTLGSASWSNSVLED
CCCCCCCCEEEEECCCCCCCEEEEEECCHHHHHCCCCCCHHHHHHHHHCCCCCCCHHHHC
RKGNVWVGQFAELVRFDPATGQVQHWKAAASGSDAAAQDATLDASLEALQQTADGHIWVH
CCCCEEHHHHHHHHHCCCCCCCHHHHEECCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEE
ATLGLQERDEQGRLLRTMLRGTHGLAADLVVYDLQAGPDGALWLASNRGLQRWNASVARF
EEECCCCCCHHHHHHHHHHHCCCCCEEEEEEEEECCCCCCEEEEECCCCHHHHHHHHHHH
ERIAGAPDEPIFTFRFSDNQIAWFAGLGKLRRYLWKNGTLQHLDTVGPEQNFPALAPQGL
HHHCCCCCCCEEEEEECCCCEEEHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCCCCCE
VIDHDGVAWMSSMRGLIRVDPATRGVRVFGVHDGLPNPQFVARSLVQSSKGMIVGATPDG
EEECCCHHHHHHCCCEEEECCCCCCEEEEEECCCCCCHHHHHHHHHHCCCCEEEECCCCC
LVIFDPAELKPNDHRVPLVIERVGLRRGESGLDLSHVTPLVMQDGDRDLHIVARLLSFAD
EEEECCCCCCCCCCCCCEEEEECCCCCCCCCCCHHHCCCCEECCCCCHHHHHHHHHHHHC
SESNSYRFRLSGYDPDWIDVGPSGERLFSRLPSGRYTLEVQGRTADGIWSASQTLRFQVL
CCCCCEEEEECCCCCCCEECCCCHHHHHHHCCCCCEEEEECCCCCCCCCCCCCEEEEEEC
PPWWLSPWGLSLLALLTVCVIAAAILLYRRRLRRLNAWQLAVHKQEVAEQASLAKTRFLA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
TLGHEVRTPMTGVLGMSELLLKTSLDLKQRSYTESIRRAGAHLLRLVNDALDLARIESGR
HHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
LELDVEPFSVRQLVAEVEALMAPLAQERGLRFSLEIGLLGDITASGDCTRIRQILLNLLN
EEEECCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEECCCCCCCHHHHHHHHHHHHH
NAIKFTERGVVGLKLTTLGSYQGLRFEVADTGPGINAEQKARLFQRFEQGDGARTTSRYG
HHHHHHCCCEEEEEEEEECCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCC
GSGLGLAICQELAIAMGGQIEVISRLGAGTRFVVDLPLRWVASNAALGGETAHAETAVEP
CCCHHHHHHHHHHHHCCCCCHHHHHCCCCCEEEEECCHHHHHCCCCCCCCCCCCCCCCCC
QRILLVEDDPTIAEVIVGLLQAQGHSVVHAPHGLAALTEAADNTFDLALLDLDLPGLDGF
CEEEEEECCCCHHHHHHHHHHCCCCCEEECCCCHHHHHHHCCCCEEEEEEEECCCCCCHH
ALARQLRVFGYDMPLIAVTARADEVAEPSAQEAGFDSFLRKPLTGDMLAATIAEALRSKR
HHHHHHHHHCCCCCEEEEEECCHHHCCCCHHHCCHHHHHHCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10952301; 12176318 [H]