Click here to switch to the map view.

The map label for this gene is luxQ [H]

Identifier: 78048723

GI number: 78048723

Start: 3594348

End: 3597881

Strand: Reverse

Name: luxQ [H]

Synonym: XCV3167

Alternate gene names: 78048723

Gene position: 3597881-3594348 (Counterclockwise)

Preceding gene: 78048724

Following gene: 78048722

Centisome position: 69.48

GC content: 66.41

Gene sequence:

>3534_bases
ATGACGATGAAGAACGTGCTGATGTCGGTGCTGGCCGTGCTCTTGCTGCTGAGCGGGCTGGATGCGGCGGCGGTGAATCA
GATCGAGACCCCGCGCATGCGCCGCTTCGGTAGTGCCGAAGGCCTGCCTTCGCGCATGGTGCTGGCCTTGGCCCAGGATC
GGCAAGGCTATGTCTGGGCGGCGACCAGCGATGGCCTTGCGCGCTATGACGGCATCGGTTTGCAGGTATGGCAGCACGAT
CCGCATGTCGCCAGTTCGATTCCGGGCAACGAAGTGGAAACGCTGTTGGTCGATGATCGCGACCGGATATGGGTTGGCAT
CAACGGCTCGCCACCGAGCATGCTGGATGCGGCGCGCTCGGCGTTTACGACATTTCCCGACGTTGGCAGCGCATGCGATG
GGCAGGTCTGGGCACTGGCCCAGGCACAAGATGCGATCTGGGTAGGAACCAGCAGCGCCGGGCTGTGCCGGCGCGAAGAA
AATGGTCGGGTGACGGCGTTCCGTGCCACACCGTATGCGGCGGACGGACTGCCCAGCAACACCATCATGAGCCTGCTGAC
CGATGCGCGCGGCCGGCTATGGATCGGCACCGACAGCGGGTTGGTGATGCGCGACGGCGAGCGCTTCGTGCGCATCGCGC
CAGACCGACTGAGCACGACGGTTTTCAAGCTCAGCAAGGATGCCGACGGTACGGTGTGGGTCGGGACCAGCAATGGCTTG
TACAGGGTGACGCCTGCTGGTGCGCTGGAACGCGCGCCCTGGAGCGGGGCCGATGCCCTGCGTGCCGCGACCGTGGTACA
CGATGTGCACGGTGGCTACTGGATTGGTGCAGCCGACGGATTTTTCCGGGTGGCGCCGGGAGAAACCGCGCTGCGCCTGA
TGGAAGGCGATCGCGGCAGCGGCTTCCTCACCGCACATAGCGGCGTGCTCGATGTGATGCAGGACCGGCAGGGCGGGCTA
TGGCTCGGACTGATTTCGCAGGGCGTGGCGTATTTGCCGCCGGACTGGCGGCGGTTCTCCACCATTTTCCAGACCCAGGG
CAAGCCGCTGGAGAGCCTGTATCTGGTCAACGCTGTGGCCGATGGCGACAGCTTTCTGGTGACGACCGGCGAAGGCGTCT
ACCGGCTCGGCAATGACGGTGAGCTGGTGCCGGTCCTGCATAGCGACGCATTGGGCGGCGGCACCGTGCAGTCGGTGCTG
CCGGCCGGCGGCGGCAGTTTGTGGATCGCGCTGCGCGATGGCGTGACGCGCTATACCCCGGAGACCGGCCAGCAGCAGAA
GCTCGCAATGCAGATCGGTGTTTCCGCAACGCATCGGGTGGAACTGATGACACCCGGCATCGATGGCGAATTCTGGGTTT
CGATCGTGGAAGGTGGCGTACAGCGACGTGCCGCGGATGGACGGCTGCTGGCCACGTTCCGCTTCGGCACCGATCTCAGT
GAAGTCGGCGGCATGGTGCAGCAACTGACGGTGCGGCCGGATGGCACCGCCTGGGTCGCAGCCGGGGATGGTGTGTGGGT
CTGGCAGGGCGAACGCTTTCGCGCAGTGATCGAGGACGCCAATCATGAAGTCTATGCGCTGGCCTTCGTGTCGCCGCGCG
AGTTCTGGGTTGGGCGTTCCGGTGCGCTGGAACGTTACGGCTGGGACGGGCGGCAGGCGCGCCTGCTGGAGCGGGTCGGG
CACGAACACGGCCTGCCTCCTACCGAGATACGCGGCCTGGCGCTGGGCGGCGACGACACGGTCTGGGCCACCACCTCGCG
GGGCCTGTACGCCTACAGGCGCGGCCAGCCGCAGGTCCGCCGGTTCGGTCCACGCGACGGCCTGCCAGATAGCGAGTTTT
CGATGCGTCCGCCGGCGATTGGTCCCAACGGCCAGGTGCTGGCGCTGACGACCAGCGGCATCGTGTTGTTCGATCCGTCG
CGGCCATTTGCGCCTGCGCCGCTGGCCCGCCTGGTGATCGAATCGGTGCAGGTGCGGCGCAACGATGCCGAGCGCCCGCA
GACGGTTGCCCACAACGCGCCGGTGATCCTGCAGGCGCGCGATCGCGATCTGCGCATCAGCGCACGGCTGTTGTCGTTTG
TCGATCCGGCCTCCGCGCATTACCGCTACCGTGTCAATGGCTACGACGAACGCTGGGTGGAGCAGGGTGCCAGCGGCGAG
CGCGTGATCTCGCGATTGCCGCCTGGCGACTACCGCATCGAGGTCCAGGCGCGTGCCGGCGATGGCGATTGGGTCGCTGC
GCCGGTGTTGCAACTGGAGGTGCGGCCGCCGTGGTGGTTGAGCACGGCCGCGCAGTTGGCGGCGGCAGCGCTCTGCATGC
TGCTGCTGTACTTAAGTGTTTGGGCCTGGCGAAAGCGCGTGCGGCGGCAGCAGGAGTGGGTGCTGACACAGCAGCGGCAA
CAGCTGGCCGAGCAGGCATCGATCGCCAAATCGCATTTCCTGGCGACGCTTGGCCACGAAGTGCGTACACCCATGACCGG
CGTGCTGGGCATGAGCGAGTTGCTGCTGGCCACGCCGCTGAATGCCAAGCAGCGCGGGTATGTCGATGCGATCTGCAAGG
CCGGCACGCATCTGCTGCGCTTGGTCAACGATGCACTGGATCTGGCACGCATCGAGGCCGGCAAGCTGGAGTTGGTACAG
CAGCCCTTCGATCCCGCGCAGCTCACCCAGGAACTGGCCGATTTCATGCATCCCATCGCTGACGCGCGCGGCCTGCGCTT
GGAGTACCGCAATCAGCTTCCCCCGCATGTGGTGGTCGTGGGCGATGCAACGCGGGTGCGTCAGATCCTGATCAACCTGC
TGGGCAATGCGATCAAGTTTGCCGAACGCGGCGAGGTGTCGCTCACCGTCAGCCAGCACGGCGATGCCCTGCGCTTCAAG
GTGCGCGATACGGGTCCTGGCATCGGGTCGGAACAGCAGAAGCGACTGTTCCAGCGCTTCGAACAAGGCGAGGGCGCGCG
CACCAGTTCGCGCTACGGCGGCAGCGGGCTTGGGCTGGCGATCTGCCAGGAACTCACCGTGGCGATGAAGGGCCGAATCC
GCGTGCGCAGCCGGCTTGGCGTCGGCACCCAGTTCACCGTGGATCTGCCCTTGCCGATCGACCGCTCCGGCACACGTATC
GCCACCGGCCAGGTGCAGGTGCCTGCAGGCGAGCCGCTGCGCATCCTGCTGGTGGAAGACGACCCGACCGTGGCGGAGGT
GATCAGCGGCTTGTTGACCAATCGAGGTCACCGCGTGGTGCATGCCGCGCATGGGCTGGCTGCATTGTCGGAAACGGTGG
ATGGCAGGTTCGACATCGCGCTGCTGGATCTGGATCTCCCCGGGCTGGACGGCTTTGCCCTGGCATCGCAGCTGCGCCAG
CTTGGCCATCGCTTCCCGCTGCTGGCAGTCACGGCACGCGCTGACAGCGCCGCGCAGACCCAGGCCAAGGCCGCAGGTTT
CGACGGATTCCTGCGCAAACCGGTCACTGCCGATCTGCTGGTGGAAGCGATTACGGCTGCGCGCGCAGCCGCCGGCATGC
AGGCCGCGACCTAG

Upstream 100 bases:

>100_bases
AGGGAGCGAGCCAGTTCCTGGGACCAAGAACTGCGGCGTAGCGGGTAAAGTGCAGTCCCAACAAGGAACGCCGGGCGCAC
ACGCGGCGATGGGGACACGG

Downstream 100 bases:

>100_bases
CGTGGGTGCACGGCCCCGATGCGTTGACGATGCCGGTGCTCATCGGGCATCGCATCGCGTAAAGACGGCCGTACGATGCC
TGCCTGCTGTAACGATCACC

Product: two-component system sensor histidine kinase-response regulator hybrid protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 1177; Mature: 1176

Protein sequence:

>1177_residues
MTMKNVLMSVLAVLLLLSGLDAAAVNQIETPRMRRFGSAEGLPSRMVLALAQDRQGYVWAATSDGLARYDGIGLQVWQHD
PHVASSIPGNEVETLLVDDRDRIWVGINGSPPSMLDAARSAFTTFPDVGSACDGQVWALAQAQDAIWVGTSSAGLCRREE
NGRVTAFRATPYAADGLPSNTIMSLLTDARGRLWIGTDSGLVMRDGERFVRIAPDRLSTTVFKLSKDADGTVWVGTSNGL
YRVTPAGALERAPWSGADALRAATVVHDVHGGYWIGAADGFFRVAPGETALRLMEGDRGSGFLTAHSGVLDVMQDRQGGL
WLGLISQGVAYLPPDWRRFSTIFQTQGKPLESLYLVNAVADGDSFLVTTGEGVYRLGNDGELVPVLHSDALGGGTVQSVL
PAGGGSLWIALRDGVTRYTPETGQQQKLAMQIGVSATHRVELMTPGIDGEFWVSIVEGGVQRRAADGRLLATFRFGTDLS
EVGGMVQQLTVRPDGTAWVAAGDGVWVWQGERFRAVIEDANHEVYALAFVSPREFWVGRSGALERYGWDGRQARLLERVG
HEHGLPPTEIRGLALGGDDTVWATTSRGLYAYRRGQPQVRRFGPRDGLPDSEFSMRPPAIGPNGQVLALTTSGIVLFDPS
RPFAPAPLARLVIESVQVRRNDAERPQTVAHNAPVILQARDRDLRISARLLSFVDPASAHYRYRVNGYDERWVEQGASGE
RVISRLPPGDYRIEVQARAGDGDWVAAPVLQLEVRPPWWLSTAAQLAAAALCMLLLYLSVWAWRKRVRRQQEWVLTQQRQ
QLAEQASIAKSHFLATLGHEVRTPMTGVLGMSELLLATPLNAKQRGYVDAICKAGTHLLRLVNDALDLARIEAGKLELVQ
QPFDPAQLTQELADFMHPIADARGLRLEYRNQLPPHVVVVGDATRVRQILINLLGNAIKFAERGEVSLTVSQHGDALRFK
VRDTGPGIGSEQQKRLFQRFEQGEGARTSSRYGGSGLGLAICQELTVAMKGRIRVRSRLGVGTQFTVDLPLPIDRSGTRI
ATGQVQVPAGEPLRILLVEDDPTVAEVISGLLTNRGHRVVHAAHGLAALSETVDGRFDIALLDLDLPGLDGFALASQLRQ
LGHRFPLLAVTARADSAAQTQAKAAGFDGFLRKPVTADLLVEAITAARAAAGMQAAT

Sequences:

>Translated_1177_residues
MTMKNVLMSVLAVLLLLSGLDAAAVNQIETPRMRRFGSAEGLPSRMVLALAQDRQGYVWAATSDGLARYDGIGLQVWQHD
PHVASSIPGNEVETLLVDDRDRIWVGINGSPPSMLDAARSAFTTFPDVGSACDGQVWALAQAQDAIWVGTSSAGLCRREE
NGRVTAFRATPYAADGLPSNTIMSLLTDARGRLWIGTDSGLVMRDGERFVRIAPDRLSTTVFKLSKDADGTVWVGTSNGL
YRVTPAGALERAPWSGADALRAATVVHDVHGGYWIGAADGFFRVAPGETALRLMEGDRGSGFLTAHSGVLDVMQDRQGGL
WLGLISQGVAYLPPDWRRFSTIFQTQGKPLESLYLVNAVADGDSFLVTTGEGVYRLGNDGELVPVLHSDALGGGTVQSVL
PAGGGSLWIALRDGVTRYTPETGQQQKLAMQIGVSATHRVELMTPGIDGEFWVSIVEGGVQRRAADGRLLATFRFGTDLS
EVGGMVQQLTVRPDGTAWVAAGDGVWVWQGERFRAVIEDANHEVYALAFVSPREFWVGRSGALERYGWDGRQARLLERVG
HEHGLPPTEIRGLALGGDDTVWATTSRGLYAYRRGQPQVRRFGPRDGLPDSEFSMRPPAIGPNGQVLALTTSGIVLFDPS
RPFAPAPLARLVIESVQVRRNDAERPQTVAHNAPVILQARDRDLRISARLLSFVDPASAHYRYRVNGYDERWVEQGASGE
RVISRLPPGDYRIEVQARAGDGDWVAAPVLQLEVRPPWWLSTAAQLAAAALCMLLLYLSVWAWRKRVRRQQEWVLTQQRQ
QLAEQASIAKSHFLATLGHEVRTPMTGVLGMSELLLATPLNAKQRGYVDAICKAGTHLLRLVNDALDLARIEAGKLELVQ
QPFDPAQLTQELADFMHPIADARGLRLEYRNQLPPHVVVVGDATRVRQILINLLGNAIKFAERGEVSLTVSQHGDALRFK
VRDTGPGIGSEQQKRLFQRFEQGEGARTSSRYGGSGLGLAICQELTVAMKGRIRVRSRLGVGTQFTVDLPLPIDRSGTRI
ATGQVQVPAGEPLRILLVEDDPTVAEVISGLLTNRGHRVVHAAHGLAALSETVDGRFDIALLDLDLPGLDGFALASQLRQ
LGHRFPLLAVTARADSAAQTQAKAAGFDGFLRKPVTADLLVEAITAARAAAGMQAAT
>Mature_1176_residues
TMKNVLMSVLAVLLLLSGLDAAAVNQIETPRMRRFGSAEGLPSRMVLALAQDRQGYVWAATSDGLARYDGIGLQVWQHDP
HVASSIPGNEVETLLVDDRDRIWVGINGSPPSMLDAARSAFTTFPDVGSACDGQVWALAQAQDAIWVGTSSAGLCRREEN
GRVTAFRATPYAADGLPSNTIMSLLTDARGRLWIGTDSGLVMRDGERFVRIAPDRLSTTVFKLSKDADGTVWVGTSNGLY
RVTPAGALERAPWSGADALRAATVVHDVHGGYWIGAADGFFRVAPGETALRLMEGDRGSGFLTAHSGVLDVMQDRQGGLW
LGLISQGVAYLPPDWRRFSTIFQTQGKPLESLYLVNAVADGDSFLVTTGEGVYRLGNDGELVPVLHSDALGGGTVQSVLP
AGGGSLWIALRDGVTRYTPETGQQQKLAMQIGVSATHRVELMTPGIDGEFWVSIVEGGVQRRAADGRLLATFRFGTDLSE
VGGMVQQLTVRPDGTAWVAAGDGVWVWQGERFRAVIEDANHEVYALAFVSPREFWVGRSGALERYGWDGRQARLLERVGH
EHGLPPTEIRGLALGGDDTVWATTSRGLYAYRRGQPQVRRFGPRDGLPDSEFSMRPPAIGPNGQVLALTTSGIVLFDPSR
PFAPAPLARLVIESVQVRRNDAERPQTVAHNAPVILQARDRDLRISARLLSFVDPASAHYRYRVNGYDERWVEQGASGER
VISRLPPGDYRIEVQARAGDGDWVAAPVLQLEVRPPWWLSTAAQLAAAALCMLLLYLSVWAWRKRVRRQQEWVLTQQRQQ
LAEQASIAKSHFLATLGHEVRTPMTGVLGMSELLLATPLNAKQRGYVDAICKAGTHLLRLVNDALDLARIEAGKLELVQQ
PFDPAQLTQELADFMHPIADARGLRLEYRNQLPPHVVVVGDATRVRQILINLLGNAIKFAERGEVSLTVSQHGDALRFKV
RDTGPGIGSEQQKRLFQRFEQGEGARTSSRYGGSGLGLAICQELTVAMKGRIRVRSRLGVGTQFTVDLPLPIDRSGTRIA
TGQVQVPAGEPLRILLVEDDPTVAEVISGLLTNRGHRVVHAAHGLAALSETVDGRFDIALLDLDLPGLDGFALASQLRQL
GHRFPLLAVTARADSAAQTQAKAAGFDGFLRKPVTADLLVEAITAARAAAGMQAAT

Specific function: At low cell density, in absence of AI-2 (autoinducer 2), luxQ has a kinase activity and autophosphorylates on a histidine residue. The phosphoryl group is then transferred to an aspartate residue in the response regulator domain. The phosphoryl group is t

COG id: COG3292

COG function: function code T; Predicted periplasmic ligand-binding sensor domain

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788713, Length=380, Percent_Identity=33.6842105263158, Blast_Score=210, Evalue=5e-55,
Organism=Escherichia coli, GI48994928, Length=375, Percent_Identity=34.6666666666667, Blast_Score=187, Evalue=3e-48,
Organism=Escherichia coli, GI87081816, Length=389, Percent_Identity=34.4473007712082, Blast_Score=182, Evalue=1e-46,
Organism=Escherichia coli, GI1789149, Length=375, Percent_Identity=32.5333333333333, Blast_Score=162, Evalue=9e-41,
Organism=Escherichia coli, GI145693157, Length=235, Percent_Identity=39.1489361702128, Blast_Score=157, Evalue=3e-39,
Organism=Escherichia coli, GI1788393, Length=244, Percent_Identity=31.5573770491803, Blast_Score=108, Evalue=3e-24,
Organism=Escherichia coli, GI1786912, Length=240, Percent_Identity=29.5833333333333, Blast_Score=97, Evalue=5e-21,
Organism=Escherichia coli, GI1786783, Length=224, Percent_Identity=31.6964285714286, Blast_Score=95, Evalue=2e-20,
Organism=Escherichia coli, GI1790436, Length=280, Percent_Identity=27.1428571428571, Blast_Score=94, Evalue=5e-20,
Organism=Escherichia coli, GI1786600, Length=225, Percent_Identity=29.3333333333333, Blast_Score=91, Evalue=5e-19,
Organism=Escherichia coli, GI1788549, Length=244, Percent_Identity=27.4590163934426, Blast_Score=82, Evalue=2e-16,
Organism=Escherichia coli, GI87082128, Length=232, Percent_Identity=27.1551724137931, Blast_Score=76, Evalue=1e-14,
Organism=Escherichia coli, GI1789808, Length=239, Percent_Identity=28.4518828451883, Blast_Score=76, Evalue=1e-14,
Organism=Escherichia coli, GI1790551, Length=220, Percent_Identity=31.8181818181818, Blast_Score=73, Evalue=1e-13,
Organism=Escherichia coli, GI1787894, Length=229, Percent_Identity=30.5676855895196, Blast_Score=71, Evalue=4e-13,
Organism=Escherichia coli, GI1790861, Length=211, Percent_Identity=28.436018957346, Blast_Score=70, Evalue=7e-13,
Organism=Escherichia coli, GI1790346, Length=232, Percent_Identity=27.5862068965517, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI1788545, Length=257, Percent_Identity=26.4591439688716, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI1790300, Length=275, Percent_Identity=27.2727272727273, Blast_Score=63, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6322044, Length=75, Percent_Identity=45.3333333333333, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR015387
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789
- ProDom:   PD142495 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF09308 LuxQ-periplasm; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 127597; Mature: 127466

Theoretical pI: Translated: 7.26; Mature: 7.26

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTMKNVLMSVLAVLLLLSGLDAAAVNQIETPRMRRFGSAEGLPSRMVLALAQDRQGYVWA
CCHHHHHHHHHHHHHHHCCCCHHHHHCCCCCHHHHCCCCCCCCHHEEEEEECCCCCEEEE
ATSDGLARYDGIGLQVWQHDPHVASSIPGNEVETLLVDDRDRIWVGINGSPPSMLDAARS
ECCCCCHHHCCCEEEEEECCCCHHCCCCCCCEEEEEEECCCEEEEEECCCCHHHHHHHHH
AFTTFPDVGSACDGQVWALAQAQDAIWVGTSSAGLCRREENGRVTAFRATPYAADGLPSN
HHCCCCCCCCCCCCCEEEEEECCCEEEEECCCCCCEEECCCCCEEEEEECCCCCCCCCHH
TIMSLLTDARGRLWIGTDSGLVMRDGERFVRIAPDRLSTTVFKLSKDADGTVWVGTSNGL
HHHHHHHCCCCEEEEECCCCEEEECCCEEEEECCCHHCEEEEEEECCCCCEEEEECCCCE
YRVTPAGALERAPWSGADALRAATVVHDVHGGYWIGAADGFFRVAPGETALRLMEGDRGS
EEECCCCCCCCCCCCCCHHHHHHHHEEECCCCEEEEECCCEEEECCCHHEEEEEECCCCC
GFLTAHSGVLDVMQDRQGGLWLGLISQGVAYLPPDWRRFSTIFQTQGKPLESLYLVNAVA
EEEEECCCHHHHHHCCCCCEEEEEHHCCCCCCCCCHHHHHHHHHCCCCCHHHEEEEEEEE
DGDSFLVTTGEGVYRLGNDGELVPVLHSDALGGGTVQSVLPAGGGSLWIALRDGVTRYTP
CCCEEEEECCCCEEEECCCCCEEEEEECCCCCCCCHHHHCCCCCCEEEEEEECCCEECCC
ETGQQQKLAMQIGVSATHRVELMTPGIDGEFWVSIVEGGVQRRAADGRLLATFRFGTDLS
CCCCHHHHHHEECCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHH
EVGGMVQQLTVRPDGTAWVAAGDGVWVWQGERFRAVIEDANHEVYALAFVSPREFWVGRS
HHCCHHHEEEECCCCCEEEEECCEEEEEECCHHHEEEECCCCCEEEEEEECCHHHHCCCC
GALERYGWDGRQARLLERVGHEHGLPPTEIRGLALGGDDTVWATTSRGLYAYRRGQPQVR
CCHHHCCCCCHHHHHHHHHHHHCCCCHHHEEEEEECCCCCEEEEECCCEEEEECCCCHHH
RFGPRDGLPDSEFSMRPPAIGPNGQVLALTTSGIVLFDPSRPFAPAPLARLVIESVQVRR
HCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCEEEECCCCCCCCCHHHHHHHHHHHHHC
NDAERPQTVAHNAPVILQARDRDLRISARLLSFVDPASAHYRYRVNGYDERWVEQGASGE
CCCCCCCHHHCCCCEEEEECCCCEEHHHHHHHHCCCCCCCEEEEECCCHHHHHHCCCCHH
RVISRLPPGDYRIEVQARAGDGDWVAAPVLQLEVRPPWWLSTAAQLAAAALCMLLLYLSV
HHHHHCCCCCEEEEEEEECCCCCEEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHH
WAWRKRVRRQQEWVLTQQRQQLAEQASIAKSHFLATLGHEVRTPMTGVLGMSELLLATPL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCC
NAKQRGYVDAICKAGTHLLRLVNDALDLARIEAGKLELVQQPFDPAQLTQELADFMHPIA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCHHHHHHHHHHHHHHHH
DARGLRLEYRNQLPPHVVVVGDATRVRQILINLLGNAIKFAERGEVSLTVSQHGDALRFK
CCCCCEEEHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEEE
VRDTGPGIGSEQQKRLFQRFEQGEGARTSSRYGGSGLGLAICQELTVAMKGRIRVRSRLG
EECCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEECCC
VGTQFTVDLPLPIDRSGTRIATGQVQVPAGEPLRILLVEDDPTVAEVISGLLTNRGHRVV
CCEEEEEEECCCCCCCCCEEEECEEECCCCCCEEEEEECCCCCHHHHHHHHHHCCCCEEE
HAAHGLAALSETVDGRFDIALLDLDLPGLDGFALASQLRQLGHRFPLLAVTARADSAAQT
EHHHHHHHHHHHCCCCEEEEEEEECCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCHHHH
QAKAAGFDGFLRKPVTADLLVEAITAARAAAGMQAAT
HHHHCCCCHHHCCCCHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TMKNVLMSVLAVLLLLSGLDAAAVNQIETPRMRRFGSAEGLPSRMVLALAQDRQGYVWA
CHHHHHHHHHHHHHHHCCCCHHHHHCCCCCHHHHCCCCCCCCHHEEEEEECCCCCEEEE
ATSDGLARYDGIGLQVWQHDPHVASSIPGNEVETLLVDDRDRIWVGINGSPPSMLDAARS
ECCCCCHHHCCCEEEEEECCCCHHCCCCCCCEEEEEEECCCEEEEEECCCCHHHHHHHHH
AFTTFPDVGSACDGQVWALAQAQDAIWVGTSSAGLCRREENGRVTAFRATPYAADGLPSN
HHCCCCCCCCCCCCCEEEEEECCCEEEEECCCCCCEEECCCCCEEEEEECCCCCCCCCHH
TIMSLLTDARGRLWIGTDSGLVMRDGERFVRIAPDRLSTTVFKLSKDADGTVWVGTSNGL
HHHHHHHCCCCEEEEECCCCEEEECCCEEEEECCCHHCEEEEEEECCCCCEEEEECCCCE
YRVTPAGALERAPWSGADALRAATVVHDVHGGYWIGAADGFFRVAPGETALRLMEGDRGS
EEECCCCCCCCCCCCCCHHHHHHHHEEECCCCEEEEECCCEEEECCCHHEEEEEECCCCC
GFLTAHSGVLDVMQDRQGGLWLGLISQGVAYLPPDWRRFSTIFQTQGKPLESLYLVNAVA
EEEEECCCHHHHHHCCCCCEEEEEHHCCCCCCCCCHHHHHHHHHCCCCCHHHEEEEEEEE
DGDSFLVTTGEGVYRLGNDGELVPVLHSDALGGGTVQSVLPAGGGSLWIALRDGVTRYTP
CCCEEEEECCCCEEEECCCCCEEEEEECCCCCCCCHHHHCCCCCCEEEEEEECCCEECCC
ETGQQQKLAMQIGVSATHRVELMTPGIDGEFWVSIVEGGVQRRAADGRLLATFRFGTDLS
CCCCHHHHHHEECCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHH
EVGGMVQQLTVRPDGTAWVAAGDGVWVWQGERFRAVIEDANHEVYALAFVSPREFWVGRS
HHCCHHHEEEECCCCCEEEEECCEEEEEECCHHHEEEECCCCCEEEEEEECCHHHHCCCC
GALERYGWDGRQARLLERVGHEHGLPPTEIRGLALGGDDTVWATTSRGLYAYRRGQPQVR
CCHHHCCCCCHHHHHHHHHHHHCCCCHHHEEEEEECCCCCEEEEECCCEEEEECCCCHHH
RFGPRDGLPDSEFSMRPPAIGPNGQVLALTTSGIVLFDPSRPFAPAPLARLVIESVQVRR
HCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCEEEECCCCCCCCCHHHHHHHHHHHHHC
NDAERPQTVAHNAPVILQARDRDLRISARLLSFVDPASAHYRYRVNGYDERWVEQGASGE
CCCCCCCHHHCCCCEEEEECCCCEEHHHHHHHHCCCCCCCEEEEECCCHHHHHHCCCCHH
RVISRLPPGDYRIEVQARAGDGDWVAAPVLQLEVRPPWWLSTAAQLAAAALCMLLLYLSV
HHHHHCCCCCEEEEEEEECCCCCEEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHH
WAWRKRVRRQQEWVLTQQRQQLAEQASIAKSHFLATLGHEVRTPMTGVLGMSELLLATPL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCC
NAKQRGYVDAICKAGTHLLRLVNDALDLARIEAGKLELVQQPFDPAQLTQELADFMHPIA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCHHHHHHHHHHHHHHHH
DARGLRLEYRNQLPPHVVVVGDATRVRQILINLLGNAIKFAERGEVSLTVSQHGDALRFK
CCCCCEEEHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEEE
VRDTGPGIGSEQQKRLFQRFEQGEGARTSSRYGGSGLGLAICQELTVAMKGRIRVRSRLG
EECCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEECCC
VGTQFTVDLPLPIDRSGTRIATGQVQVPAGEPLRILLVEDDPTVAEVISGLLTNRGHRVV
CCEEEEEEECCCCCCCCCEEEECEEECCCCCCEEEEEECCCCCHHHHHHHHHHCCCCEEE
HAAHGLAALSETVDGRFDIALLDLDLPGLDGFALASQLRQLGHRFPLLAVTARADSAAQT
EHHHHHHHHHHHCCCCEEEEEEEECCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCHHHH
QAKAAGFDGFLRKPVTADLLVEAITAARAAAGMQAAT
HHHHCCCCHHHCCCCHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10952301; 12176318 [H]