Click here to switch to the map view.

The map label for this gene is hda [H]

Identifier: 78048657

GI number: 78048657

Start: 3522226

End: 3522933

Strand: Reverse

Name: hda [H]

Synonym: XCV3101

Alternate gene names: 78048657

Gene position: 3522933-3522226 (Counterclockwise)

Preceding gene: 78048658

Following gene: 78048652

Centisome position: 68.03

GC content: 69.07

Gene sequence:

>708_bases
GTGAGTGTTCCGCAGTTGCCGCTGGCGTTGCGCGCGCCACCCGATCAGCGTTTCGACAGTTACATCGCCGCGCCCGACGG
CCTGCTTGCGCAGTTGCAGGCGCTGGCTGCGGGGCATGTGAGCGATTGGTTGTATCTCTCCGGCCCCGCCGGCACCGGCA
AGACGCATCTGGCGCTGTCGCTGTGCGCCGCCGCCGAGCAGGCCGGGCGCACTCCCGCGTATCTGCCGCTGCAGGCGGCC
GCCGGCCGCTTGCGCGATGCGCTCGAAGCGCTGGAAGGCCGCGGCCTGGTCGCTCTGGATGGCGTGGAAAGCATCGCCGG
CCGACGCGACGACGAAGTGGCGTTGTTCGATTTCCACAATCGCGCGCGCGCGGCCGGCATCACGCTGTTGTACACCGCGC
GACAGATGCCCGATGGGCTGGCGTTGGTGTTGCCGGACCTGCGTTCGCGGCTGTCGCAATGCATTCGGATCGGGTTGCCC
GTGCTCGACGATGCGGCACGCGGGGCAGTACTGCGCGACCGCGCGCAGCGTCGCGGCCTGGCGCTGGACGAAGCGGCGAT
CGACTGGCTGCTGACCCACAGCGAGCGCGAACTGGCGGGGCTGGTGGCCTTGCTGGATCGTCTGGATCGCGAATCGTTGG
CCGCAAAACGCCGCATCACCGTGCCATTTCTGCGGCGTGTGGTAGCGGGGATGCCGGGACCCGAATAA

Upstream 100 bases:

>100_bases
CGCGCAGCGATCTGTATGCGGGCGAGCGCGCCGGCATCGTGCTGCAGTCCACGCCCGAGCGCAGCGTGATCATCGACCCC
AGCAAGGACCCGGACCGGTC

Downstream 100 bases:

>100_bases
CGCAGAAGCGAAGCGGGTCGCGGTGCAGTTGTGCCGTGTGTTGGATACGCTGCGGTGGATCGGCGGCAGGTAATGCCCAC
GCCCTGGCGCGTCAGCTTTT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 235; Mature: 234

Protein sequence:

>235_residues
MSVPQLPLALRAPPDQRFDSYIAAPDGLLAQLQALAAGHVSDWLYLSGPAGTGKTHLALSLCAAAEQAGRTPAYLPLQAA
AGRLRDALEALEGRGLVALDGVESIAGRRDDEVALFDFHNRARAAGITLLYTARQMPDGLALVLPDLRSRLSQCIRIGLP
VLDDAARGAVLRDRAQRRGLALDEAAIDWLLTHSERELAGLVALLDRLDRESLAAKRRITVPFLRRVVAGMPGPE

Sequences:

>Translated_235_residues
MSVPQLPLALRAPPDQRFDSYIAAPDGLLAQLQALAAGHVSDWLYLSGPAGTGKTHLALSLCAAAEQAGRTPAYLPLQAA
AGRLRDALEALEGRGLVALDGVESIAGRRDDEVALFDFHNRARAAGITLLYTARQMPDGLALVLPDLRSRLSQCIRIGLP
VLDDAARGAVLRDRAQRRGLALDEAAIDWLLTHSERELAGLVALLDRLDRESLAAKRRITVPFLRRVVAGMPGPE
>Mature_234_residues
SVPQLPLALRAPPDQRFDSYIAAPDGLLAQLQALAAGHVSDWLYLSGPAGTGKTHLALSLCAAAEQAGRTPAYLPLQAAA
GRLRDALEALEGRGLVALDGVESIAGRRDDEVALFDFHNRARAAGITLLYTARQMPDGLALVLPDLRSRLSQCIRIGLPV
LDDAARGAVLRDRAQRRGLALDEAAIDWLLTHSERELAGLVALLDRLDRESLAAKRRITVPFLRRVVAGMPGPE

Specific function: Mediates the interactions of dnaA with the beta subunit sliding clamp, promoting hydrolysis of dnaA-bound ATP. It is essential for the control of initiation of DNA replication by inhibiting reinitiation of replication [H]

COG id: COG0593

COG function: function code L; ATPase involved in DNA replication initiation

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dnaA family. HdA subfamily [H]

Homologues:

Organism=Escherichia coli, GI226510964, Length=231, Percent_Identity=36.7965367965368, Blast_Score=124, Evalue=6e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020591
- InterPro:   IPR017788
- InterPro:   IPR013317
- InterPro:   IPR022864 [H]

Pfam domain/function: PF00308 Bac_DnaA [H]

EC number: NA

Molecular weight: Translated: 25214; Mature: 25083

Theoretical pI: Translated: 7.58; Mature: 7.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVPQLPLALRAPPDQRFDSYIAAPDGLLAQLQALAAGHVSDWLYLSGPAGTGKTHLALS
CCCCCCCEEEECCCCHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHH
LCAAAEQAGRTPAYLPLQAAAGRLRDALEALEGRGLVALDGVESIAGRRDDEVALFDFHN
HHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHCCCCEEEECCHHHHHCCCCCCEEEEECCC
RARAAGITLLYTARQMPDGLALVLPDLRSRLSQCIRIGLPVLDDAARGAVLRDRAQRRGL
HHHHHCEEEEEEHHHCCCCCEEECHHHHHHHHHHHHHCCCHHCHHHCCHHHHHHHHHCCC
ALDEAAIDWLLTHSERELAGLVALLDRLDRESLAAKRRITVPFLRRVVAGMPGPE
CHHHHHHHHHHHCCHHHHHHHHHHHHHHCHHHHHHHCCCCHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SVPQLPLALRAPPDQRFDSYIAAPDGLLAQLQALAAGHVSDWLYLSGPAGTGKTHLALS
CCCCCCEEEECCCCHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHH
LCAAAEQAGRTPAYLPLQAAAGRLRDALEALEGRGLVALDGVESIAGRRDDEVALFDFHN
HHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHCCCCEEEECCHHHHHCCCCCCEEEEECCC
RARAAGITLLYTARQMPDGLALVLPDLRSRLSQCIRIGLPVLDDAARGAVLRDRAQRRGL
HHHHHCEEEEEEHHHCCCCCEEECHHHHHHHHHHHHHCCCHHCHHHCCHHHHHHHHHCCC
ALDEAAIDWLLTHSERELAGLVALLDRLDRESLAAKRRITVPFLRRVVAGMPGPE
CHHHHHHHHHHHCCHHHHHHHHHHHHHHCHHHHHHHCCCCHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA