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The map label for this gene is lig3 [H]

Identifier: 78048168

GI number: 78048168

Start: 2945662

End: 2948280

Strand: Reverse

Name: lig3 [H]

Synonym: XCV2612

Alternate gene names: 78048168

Gene position: 2948280-2945662 (Counterclockwise)

Preceding gene: 78048169

Following gene: 78048166

Centisome position: 56.93

GC content: 65.52

Gene sequence:

>2619_bases
ATGAGCCTGAGCGAATATCGCCGCAAGCGCAGCTTCAACAAGACCCGCGAGCCGGAGCCGGGCAAGGCCCTGCCGCCGGG
GCAGCGTGCGATCTTCGTGGTGCAACTGCACCACGCCAGCCGCCGCCATTACGACTTTCGCCTGCAGGTGGGCGATGCGC
TCAAGAGCTGGGCGGTGCCGAAGGGGCCCAGTTACGACCCCAAGGTCAAGCGCATGGCAGTGGAGGTGGAAGACCACCCG
GTCGATTACGCCAGTTTCGAGGGCGAGATTCCCAAAGGCGAATACGGCGGCGGGCATGTGGCGCAGTTCGATCATGGCGT
ATGGGCCACCGCGGGCGACCCCGAAGCGCAGTTGGCCAAGGGACATCTGCGCTTTGAGTTGTTCGGCAACAAGCTCAAGG
GCGGCTGGCATCTGGTGCGCTCGGGCAAGCCGGCGCGGCAGCCGCAGTGGCTGCTGTTCAAGGACGACGATGCCTACGCC
GTCACGTTGGAGGCCGATGACCTGCTGGCCGACGTCGCTGCCGCGCCTGCCGAGGATGTACGCCGCGCAGGCGCCGGCAA
GACCCAGCGCAAGGCGCTGACGACCGTACCGCCGCTGGCGGCGAAGAGGCGTGGTACCTGGGCAAAACAGGCGCTGGCGC
TGAGCAACGCACGTCGCGCCCAGATGGAAGATGCCCCGTTCGCACCACAGCTGGCCAAGCTGGGGCAGTCCCCGCCAGAA
GGAGCGCAATGGCTGCATGAAATCAAATGGGACGGTTATCGCATCCTGGCCACTGTGACCGACGGCAATGTGAGGCTATG
GTCGCGCAATGCATTGGAATGGACCGACAAGACGCCGGAAATTGCCGATGCCATCCGGTCGCTGGGCCTGCGCAGCGCGC
AGCTCGATGGCGAACTGATCGCCGGACGCGGCACCAAGGACGACTTCAACCTGCTGCAGGCCACCTTGTCCGGCGAACGC
CAGGTGCCGCTGGCGCTGGCGGTATTCGACCTGCTGCATGTGGACGGGGTGGACATCAGCGAGGCGCCGCTGCGCGAACG
CAAGCGGCTGTTGCAGCAGGTGCTGGAGGCTGCACCTCACACGCATCTGGCCTATAGCTCGCACGTCGAAGGCGATGGCA
CCGAGGCATTCCGGGTGGCCGGGCAACAGCACTTCGAAGGCATCATTTCCAAGCGCGCAGATCGCCCGTATCGCGATGGG
CGTAGCGACGATTGGCGCAAGACCAAGCAACTGGCCAGCCAGGAGTATGCGGTGGTCGGCTACACCGCGCCCAAGGGCAG
CCGCAGTGGCTTCGGCTCGCTGTTGCTGGCCACGCCGGACCCGGTGCATGGCTGGTTGTACGTGGGCCGTGTGGGCTCCG
GGTTCTCCGATGCCTTGATGCGCGAGGTCACCCCGCAACTGGAAGGTGGCGGGCGCAAACCCACCGCGCATATTCCCACC
GAAGACACCGACCTGCGCGGCGCCACCTGGTTTGCGCCGCGCTTTGTGGTGGAGGTGTTCTATCGCGGCATTGGTGGGCA
ACAGTTGTTGCGCCAGGCATCGTTCAAGGCGCTGCGCCCGGATAAGCGCATTGCCGATCTGGCCGACAGCGATGCCGGAA
ATGGCCCGGCTACACCGTCCTCTGCCAGGCGTTCGGCAACAACGCGTGCTGCCAAAGACGCAGCAACGCAGGTGCCCAAA
CGTGCAGCGACGCGGGCAACAGCGCCTGCGCGCAAATCTGCGGTTGCCACACCTTCCTCGGCTGCGCTGCCGACGCTGTC
CAGCCCGACCAAGCTGATCTACCCGGATATCCGCGCGACCAAGGGCGATGTCTGGGACTATTACCAGGCGGTGATGGACC
ACCTGTTGCCGCAGATCGTGGGACGGCCGCTGTCCATCATCCGCTGCCCCAGCGGCGCGGAAAAACCGTGTTTTTTCCAG
AAGCACCATACTGCCGGCCTCGAGCGTGTGAGCTCGGTCAAGCTGACCGAAGAGACCGGAACCAACGCGTATTACCTGGT
GGTCGAAGACGCGCCTGGCCTGCTGGAACTGGTGCAATTCAATGCGTTGGAATTCCACCCCTGGGGCTCGCATGCGGACC
GCCCGGACGTGGCCGACCGGGTGGTCTTCGATCTCGATCCGGGCCCGGACGTGCCGTTTGCCGAGGTCAAACGCGCGGCC
AACGATATTCGCAAGCTGCTGGCGCAGCTTGAGCTGGAATCGTTCCTGCGTGTGTCTGGCGGCAAGGGGCTGCACGTGGT
GGTGCCCCTAAACCCCGGCTGCGATTGGGAGGTGACCAAGCGTTTCGCCAAGGGATTTGCCGATGCCCTGGCGCAGGCGC
AGCCGCAGCGGTTCATCGCCACTGCCACCAAGCGGCTGCGCAACAAGCGCATCTTCGTGGACTACCTGCGCAACGGCCGT
GGCGCCACTGCGGTTGCGTCCTATTCGTTACGCGGCCGCCCGGGGGCGCCAGTCGCGTTGCCGCTGGCGTGGTCGGACCT
GTCCAAGCTGCAGCGCGCCGATGCATTCACCTTGCGCGATGTCCCGGAGAAGCTGCGCCGTCGGCGCAAGGACCCCTGGG
CAGACATGGACGGCATCCGGCAAAACCTGGCGCGCTGGGCAGAACAGGACCAGGACTGA

Upstream 100 bases:

>100_bases
TGGGCGTCAGCGCCGAGCAGTTGCGCGCGGCCGTGCAGAAGGTGGGGCCAATGGCCGCCAGCGTACGCCAGCACCTGGGC
AAATAAGCGGAAGGTCTGTC

Downstream 100 bases:

>100_bases
TGTGATGCGACGCAGAGAATGCCGGCGTCGCCGCCGCGCGGGCGCGACCGGTAGCGAAATCGCCGTGCGACGCAGGCGCT
TCGCAAGGTCCTCACGCCTT

Product: ATP-dependent DNA ligase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 872; Mature: 871

Protein sequence:

>872_residues
MSLSEYRRKRSFNKTREPEPGKALPPGQRAIFVVQLHHASRRHYDFRLQVGDALKSWAVPKGPSYDPKVKRMAVEVEDHP
VDYASFEGEIPKGEYGGGHVAQFDHGVWATAGDPEAQLAKGHLRFELFGNKLKGGWHLVRSGKPARQPQWLLFKDDDAYA
VTLEADDLLADVAAAPAEDVRRAGAGKTQRKALTTVPPLAAKRRGTWAKQALALSNARRAQMEDAPFAPQLAKLGQSPPE
GAQWLHEIKWDGYRILATVTDGNVRLWSRNALEWTDKTPEIADAIRSLGLRSAQLDGELIAGRGTKDDFNLLQATLSGER
QVPLALAVFDLLHVDGVDISEAPLRERKRLLQQVLEAAPHTHLAYSSHVEGDGTEAFRVAGQQHFEGIISKRADRPYRDG
RSDDWRKTKQLASQEYAVVGYTAPKGSRSGFGSLLLATPDPVHGWLYVGRVGSGFSDALMREVTPQLEGGGRKPTAHIPT
EDTDLRGATWFAPRFVVEVFYRGIGGQQLLRQASFKALRPDKRIADLADSDAGNGPATPSSARRSATTRAAKDAATQVPK
RAATRATAPARKSAVATPSSAALPTLSSPTKLIYPDIRATKGDVWDYYQAVMDHLLPQIVGRPLSIIRCPSGAEKPCFFQ
KHHTAGLERVSSVKLTEETGTNAYYLVVEDAPGLLELVQFNALEFHPWGSHADRPDVADRVVFDLDPGPDVPFAEVKRAA
NDIRKLLAQLELESFLRVSGGKGLHVVVPLNPGCDWEVTKRFAKGFADALAQAQPQRFIATATKRLRNKRIFVDYLRNGR
GATAVASYSLRGRPGAPVALPLAWSDLSKLQRADAFTLRDVPEKLRRRRKDPWADMDGIRQNLARWAEQDQD

Sequences:

>Translated_872_residues
MSLSEYRRKRSFNKTREPEPGKALPPGQRAIFVVQLHHASRRHYDFRLQVGDALKSWAVPKGPSYDPKVKRMAVEVEDHP
VDYASFEGEIPKGEYGGGHVAQFDHGVWATAGDPEAQLAKGHLRFELFGNKLKGGWHLVRSGKPARQPQWLLFKDDDAYA
VTLEADDLLADVAAAPAEDVRRAGAGKTQRKALTTVPPLAAKRRGTWAKQALALSNARRAQMEDAPFAPQLAKLGQSPPE
GAQWLHEIKWDGYRILATVTDGNVRLWSRNALEWTDKTPEIADAIRSLGLRSAQLDGELIAGRGTKDDFNLLQATLSGER
QVPLALAVFDLLHVDGVDISEAPLRERKRLLQQVLEAAPHTHLAYSSHVEGDGTEAFRVAGQQHFEGIISKRADRPYRDG
RSDDWRKTKQLASQEYAVVGYTAPKGSRSGFGSLLLATPDPVHGWLYVGRVGSGFSDALMREVTPQLEGGGRKPTAHIPT
EDTDLRGATWFAPRFVVEVFYRGIGGQQLLRQASFKALRPDKRIADLADSDAGNGPATPSSARRSATTRAAKDAATQVPK
RAATRATAPARKSAVATPSSAALPTLSSPTKLIYPDIRATKGDVWDYYQAVMDHLLPQIVGRPLSIIRCPSGAEKPCFFQ
KHHTAGLERVSSVKLTEETGTNAYYLVVEDAPGLLELVQFNALEFHPWGSHADRPDVADRVVFDLDPGPDVPFAEVKRAA
NDIRKLLAQLELESFLRVSGGKGLHVVVPLNPGCDWEVTKRFAKGFADALAQAQPQRFIATATKRLRNKRIFVDYLRNGR
GATAVASYSLRGRPGAPVALPLAWSDLSKLQRADAFTLRDVPEKLRRRRKDPWADMDGIRQNLARWAEQDQD
>Mature_871_residues
SLSEYRRKRSFNKTREPEPGKALPPGQRAIFVVQLHHASRRHYDFRLQVGDALKSWAVPKGPSYDPKVKRMAVEVEDHPV
DYASFEGEIPKGEYGGGHVAQFDHGVWATAGDPEAQLAKGHLRFELFGNKLKGGWHLVRSGKPARQPQWLLFKDDDAYAV
TLEADDLLADVAAAPAEDVRRAGAGKTQRKALTTVPPLAAKRRGTWAKQALALSNARRAQMEDAPFAPQLAKLGQSPPEG
AQWLHEIKWDGYRILATVTDGNVRLWSRNALEWTDKTPEIADAIRSLGLRSAQLDGELIAGRGTKDDFNLLQATLSGERQ
VPLALAVFDLLHVDGVDISEAPLRERKRLLQQVLEAAPHTHLAYSSHVEGDGTEAFRVAGQQHFEGIISKRADRPYRDGR
SDDWRKTKQLASQEYAVVGYTAPKGSRSGFGSLLLATPDPVHGWLYVGRVGSGFSDALMREVTPQLEGGGRKPTAHIPTE
DTDLRGATWFAPRFVVEVFYRGIGGQQLLRQASFKALRPDKRIADLADSDAGNGPATPSSARRSATTRAAKDAATQVPKR
AATRATAPARKSAVATPSSAALPTLSSPTKLIYPDIRATKGDVWDYYQAVMDHLLPQIVGRPLSIIRCPSGAEKPCFFQK
HHTAGLERVSSVKLTEETGTNAYYLVVEDAPGLLELVQFNALEFHPWGSHADRPDVADRVVFDLDPGPDVPFAEVKRAAN
DIRKLLAQLELESFLRVSGGKGLHVVVPLNPGCDWEVTKRFAKGFADALAQAQPQRFIATATKRLRNKRIFVDYLRNGRG
ATAVASYSLRGRPGAPVALPLAWSDLSKLQRADAFTLRDVPEKLRRRRKDPWADMDGIRQNLARWAEQDQD

Specific function: Probably involved in the repair of DNA double-strand breaks by non-homologous-end joining (NHEJ) during spore germination [H]

COG id: COG1793

COG function: function code L; ATP-dependent DNA ligase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATP-dependent DNA ligase family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6320038, Length=361, Percent_Identity=25.207756232687, Blast_Score=74, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012310
- InterPro:   IPR014146
- InterPro:   IPR014145
- InterPro:   IPR014143 [H]

Pfam domain/function: PF01068 DNA_ligase_A_M [H]

EC number: =6.5.1.1 [H]

Molecular weight: Translated: 96113; Mature: 95981

Theoretical pI: Translated: 9.98; Mature: 9.98

Prosite motif: PS50160 DNA_LIGASE_A3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLSEYRRKRSFNKTREPEPGKALPPGQRAIFVVQLHHASRRHYDFRLQVGDALKSWAVP
CCHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCEEEEEEECHHHHHCCCC
KGPSYDPKVKRMAVEVEDHPVDYASFEGEIPKGEYGGGHVAQFDHGVWATAGDPEAQLAK
CCCCCCCCCEEEEEEECCCCCCHHHCCCCCCCCCCCCCEEEEECCCEEECCCCCHHHHHC
GHLRFELFGNKLKGGWHLVRSGKPARQPQWLLFKDDDAYAVTLEADDLLADVAAAPAEDV
CCEEEEEECCCCCCCEEEEECCCCCCCCCEEEEECCCCEEEEEEHHHHHHHHHCCCHHHH
RRAGAGKTQRKALTTVPPLAAKRRGTWAKQALALSNARRAQMEDAPFAPQLAKLGQSPPE
HHCCCCCHHHHHHCCCCCHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCH
GAQWLHEIKWDGYRILATVTDGNVRLWSRNALEWTDKTPEIADAIRSLGLRSAQLDGELI
HHHHHHHHCCCCEEEEEEEECCCEEEEECCCCCCCCCCHHHHHHHHHCCCCCCCCCCEEE
AGRGTKDDFNLLQATLSGERQVPLALAVFDLLHVDGVDISEAPLRERKRLLQQVLEAAPH
ECCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCC
THLAYSSHVEGDGTEAFRVAGQQHFEGIISKRADRPYRDGRSDDWRKTKQLASQEYAVVG
CEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCEEEEE
YTAPKGSRSGFGSLLLATPDPVHGWLYVGRVGSGFSDALMREVTPQLEGGGRKPTAHIPT
EECCCCCCCCCCEEEEECCCCCCCEEEEECCCCCHHHHHHHHHCHHHCCCCCCCCCCCCC
EDTDLRGATWFAPRFVVEVFYRGIGGQQLLRQASFKALRPDKRIADLADSDAGNGPATPS
CCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCC
SARRSATTRAAKDAATQVPKRAATRATAPARKSAVATPSSAALPTLSSPTKLIYPDIRAT
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCCCCCCCEEEECCCCCC
KGDVWDYYQAVMDHLLPQIVGRPLSIIRCPSGAEKPCFFQKHHTAGLERVSSVKLTEETG
CCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCEEHHHHHHHHHHHHHEEEECCCC
TNAYYLVVEDAPGLLELVQFNALEFHPWGSHADRPDVADRVVFDLDPGPDVPFAEVKRAA
CCEEEEEEECCCCHHHHHHHCCEEECCCCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHH
NDIRKLLAQLELESFLRVSGGKGLHVVVPLNPGCDWEVTKRFAKGFADALAQAQPQRFIA
HHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCHHHHHH
TATKRLRNKRIFVDYLRNGRGATAVASYSLRGRPGAPVALPLAWSDLSKLQRADAFTLRD
HHHHHHHCCCEEEHHHHCCCCCEEEEEEEECCCCCCCEEEEECHHHHHHHHHHCCHHHHH
VPEKLRRRRKDPWADMDGIRQNLARWAEQDQD
HHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SLSEYRRKRSFNKTREPEPGKALPPGQRAIFVVQLHHASRRHYDFRLQVGDALKSWAVP
CHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCEEEEEEECHHHHHCCCC
KGPSYDPKVKRMAVEVEDHPVDYASFEGEIPKGEYGGGHVAQFDHGVWATAGDPEAQLAK
CCCCCCCCCEEEEEEECCCCCCHHHCCCCCCCCCCCCCEEEEECCCEEECCCCCHHHHHC
GHLRFELFGNKLKGGWHLVRSGKPARQPQWLLFKDDDAYAVTLEADDLLADVAAAPAEDV
CCEEEEEECCCCCCCEEEEECCCCCCCCCEEEEECCCCEEEEEEHHHHHHHHHCCCHHHH
RRAGAGKTQRKALTTVPPLAAKRRGTWAKQALALSNARRAQMEDAPFAPQLAKLGQSPPE
HHCCCCCHHHHHHCCCCCHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCH
GAQWLHEIKWDGYRILATVTDGNVRLWSRNALEWTDKTPEIADAIRSLGLRSAQLDGELI
HHHHHHHHCCCCEEEEEEEECCCEEEEECCCCCCCCCCHHHHHHHHHCCCCCCCCCCEEE
AGRGTKDDFNLLQATLSGERQVPLALAVFDLLHVDGVDISEAPLRERKRLLQQVLEAAPH
ECCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCC
THLAYSSHVEGDGTEAFRVAGQQHFEGIISKRADRPYRDGRSDDWRKTKQLASQEYAVVG
CEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCEEEEE
YTAPKGSRSGFGSLLLATPDPVHGWLYVGRVGSGFSDALMREVTPQLEGGGRKPTAHIPT
EECCCCCCCCCCEEEEECCCCCCCEEEEECCCCCHHHHHHHHHCHHHCCCCCCCCCCCCC
EDTDLRGATWFAPRFVVEVFYRGIGGQQLLRQASFKALRPDKRIADLADSDAGNGPATPS
CCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCC
SARRSATTRAAKDAATQVPKRAATRATAPARKSAVATPSSAALPTLSSPTKLIYPDIRAT
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCCCCCCCEEEECCCCCC
KGDVWDYYQAVMDHLLPQIVGRPLSIIRCPSGAEKPCFFQKHHTAGLERVSSVKLTEETG
CCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCEEHHHHHHHHHHHHHEEEECCCC
TNAYYLVVEDAPGLLELVQFNALEFHPWGSHADRPDVADRVVFDLDPGPDVPFAEVKRAA
CCEEEEEEECCCCHHHHHHHCCEEECCCCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHH
NDIRKLLAQLELESFLRVSGGKGLHVVVPLNPGCDWEVTKRFAKGFADALAQAQPQRFIA
HHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCHHHHHH
TATKRLRNKRIFVDYLRNGRGATAVASYSLRGRPGAPVALPLAWSDLSKLQRADAFTLRD
HHHHHHHCCCEEEHHHHCCCCCEEEEEEEECCCCCCCEEEEECHHHHHHHHHHCCHHHHH
VPEKLRRRRKDPWADMDGIRQNLARWAEQDQD
HHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]