Click here to switch to the map view.

The map label for this gene is galU [H]

Identifier: 78048046

GI number: 78048046

Start: 2810887

End: 2811780

Strand: Reverse

Name: galU [H]

Synonym: XCV2490

Alternate gene names: 78048046

Gene position: 2811780-2810887 (Counterclockwise)

Preceding gene: 78048047

Following gene: 78048045

Centisome position: 54.3

GC content: 62.3

Gene sequence:

>894_bases
ATGAGCCAGCGTATTCGCAAGGCCGTATTCCCCGTCGCAGGTCTTGGGACCCGCTTTCTTCCGGCAACCAAGACAGTGCC
GAAAGAAATGCTGCCAATCATCGACAAGCCATTGATCCAGTACGCCGTCGACGAAGCCATCCAGGCTGGTTGCGATACGC
TGATCTTCGTTACCAACCGCTACAAGCACTCCATTGCCGACTACTTCGACAAAGCCTATGAGCTCGAGCAGAAGCTGGAG
CGCGCAGGCAAGCTGGAGCAGCTGGAGCTGGTGCGCCATGCATTGCCCGAGGGCGTCCGCGCCATTTTTGTCACGCAGGC
AGAGGCGCTTGGCCTGGGCCATGCGGTGTTGTGTGCCAAGGCCGTTGTCGGTGACGAGCCGTTCGCGGTGTTGCTGCCGG
ACGATCTGATGTGGAACCGCGGCGATGCTGCGCTGACCCAGATGGCCAATGTGGCCGAGGCCTCGGGCGGCAGCGTGATC
GCCGTGGAAGACGTGCCGCACGACAAGACCGCCAGCTACGGCATCGTTTCCACCGACGCGTTCGACGGCCGCAAGGGCCG
CATCAACGCGATCGTCGAAAAGCCCAAGCCGGAAGTCGCGCCAAGCAACCTGGCCGTGGTCGGTCGTTACGTGCTGAGCC
CCAAGATCTTCGACCTGCTCGAAGCCACCGGTGCAGGCGCGGGCGGCGAAATCCAGCTTACCGATGCGATTGCCGAGTTG
CTGAAGGAAGAGCAGGTCGATGCCTTCCGTTTCGAAGGTCGCCGTTTCGATTGCGGCGCGCACATCGGCCTGATCGAAGC
CACCGTGCATTTCGCGCTTGAGCACGAAAAGCATGGCGGCCCAGCGAAGGAAATCCTGCGCAATGCACTGGCCCAGGCCG
ACGCGCGCGGCTGA

Upstream 100 bases:

>100_bases
TGGGTAGCCTGATGCCGGATTTCGCGGCTGCTCGACGGAAAGTCGACGCGCGATCTGATACGGTCGTTCCATTCCCCGCA
CGTGAGGTCAGAAGACTGTA

Downstream 100 bases:

>100_bases
GTGTTGCCTGATCGCTGTTTCCACGAACGACGCCAGCTGGCGTCGTTCGTCGTTTAGGGGCTTGCCGTATGCTTTGCCGC
GCCGGCAGAGCTCGGCTTGG

Product: UTP-glucose-1-phosphate uridylyltransferase

Products: NA

Alternate protein names: Alpha-D-glucosyl-1-phosphate uridylyltransferase 2; UDP-glucose pyrophosphorylase 2; UDPGP 2; Uridine diphosphoglucose pyrophosphorylase 2 [H]

Number of amino acids: Translated: 297; Mature: 296

Protein sequence:

>297_residues
MSQRIRKAVFPVAGLGTRFLPATKTVPKEMLPIIDKPLIQYAVDEAIQAGCDTLIFVTNRYKHSIADYFDKAYELEQKLE
RAGKLEQLELVRHALPEGVRAIFVTQAEALGLGHAVLCAKAVVGDEPFAVLLPDDLMWNRGDAALTQMANVAEASGGSVI
AVEDVPHDKTASYGIVSTDAFDGRKGRINAIVEKPKPEVAPSNLAVVGRYVLSPKIFDLLEATGAGAGGEIQLTDAIAEL
LKEEQVDAFRFEGRRFDCGAHIGLIEATVHFALEHEKHGGPAKEILRNALAQADARG

Sequences:

>Translated_297_residues
MSQRIRKAVFPVAGLGTRFLPATKTVPKEMLPIIDKPLIQYAVDEAIQAGCDTLIFVTNRYKHSIADYFDKAYELEQKLE
RAGKLEQLELVRHALPEGVRAIFVTQAEALGLGHAVLCAKAVVGDEPFAVLLPDDLMWNRGDAALTQMANVAEASGGSVI
AVEDVPHDKTASYGIVSTDAFDGRKGRINAIVEKPKPEVAPSNLAVVGRYVLSPKIFDLLEATGAGAGGEIQLTDAIAEL
LKEEQVDAFRFEGRRFDCGAHIGLIEATVHFALEHEKHGGPAKEILRNALAQADARG
>Mature_296_residues
SQRIRKAVFPVAGLGTRFLPATKTVPKEMLPIIDKPLIQYAVDEAIQAGCDTLIFVTNRYKHSIADYFDKAYELEQKLER
AGKLEQLELVRHALPEGVRAIFVTQAEALGLGHAVLCAKAVVGDEPFAVLLPDDLMWNRGDAALTQMANVAEASGGSVIA
VEDVPHDKTASYGIVSTDAFDGRKGRINAIVEKPKPEVAPSNLAVVGRYVLSPKIFDLLEATGAGAGGEIQLTDAIAELL
KEEQVDAFRFEGRRFDCGAHIGLIEATVHFALEHEKHGGPAKEILRNALAQADARG

Specific function: Catalyzes the formation of UDP-glucose from glucose-1- phosphate and UTP. This is an intermediate step in the biosynthesis of diglucosyl-diacylglycerol (Glc2-DAG), i.e. a glycolipid found in the membrane, which is also used as a membrane anchor for lipote

COG id: COG1210

COG function: function code M; UDP-glucose pyrophosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDPGP type 2 family [H]

Homologues:

Organism=Escherichia coli, GI1787488, Length=299, Percent_Identity=47.1571906354515, Blast_Score=244, Evalue=3e-66,
Organism=Escherichia coli, GI1788355, Length=297, Percent_Identity=42.4242424242424, Blast_Score=223, Evalue=2e-59,
Organism=Escherichia coli, GI1788351, Length=285, Percent_Identity=25.9649122807018, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1790224, Length=277, Percent_Identity=25.2707581227437, Blast_Score=74, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI133931050, Length=255, Percent_Identity=30.5882352941176, Blast_Score=78, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6320148, Length=298, Percent_Identity=25.8389261744966, Blast_Score=73, Evalue=7e-14,
Organism=Drosophila melanogaster, GI21355443, Length=257, Percent_Identity=25.2918287937743, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24644084, Length=257, Percent_Identity=25.2918287937743, Blast_Score=66, Evalue=3e-11,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 260 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005771
- InterPro:   IPR005835 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.9 [H]

Molecular weight: Translated: 32074; Mature: 31943

Theoretical pI: Translated: 5.42; Mature: 5.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQRIRKAVFPVAGLGTRFLPATKTVPKEMLPIIDKPLIQYAVDEAIQAGCDTLIFVTNR
CCHHHHHHHCCHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECH
YKHSIADYFDKAYELEQKLERAGKLEQLELVRHALPEGVRAIFVTQAEALGLGHAVLCAK
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCEEEEEEHHHHHCCCHHHHHHH
AVVGDEPFAVLLPDDLMWNRGDAALTQMANVAEASGGSVIAVEDVPHDKTASYGIVSTDA
HHHCCCCEEEEECCHHCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCEEECCC
FDGRKGRINAIVEKPKPEVAPSNLAVVGRYVLSPKIFDLLEATGAGAGGEIQLTDAIAEL
CCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHCHHHHHHHHHHCCCCCCEEEEHHHHHHH
LKEEQVDAFRFEGRRFDCGAHIGLIEATVHFALEHEKHGGPAKEILRNALAQADARG
HHHHCCHHHHCCCCEECCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SQRIRKAVFPVAGLGTRFLPATKTVPKEMLPIIDKPLIQYAVDEAIQAGCDTLIFVTNR
CHHHHHHHCCHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECH
YKHSIADYFDKAYELEQKLERAGKLEQLELVRHALPEGVRAIFVTQAEALGLGHAVLCAK
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCEEEEEEHHHHHCCCHHHHHHH
AVVGDEPFAVLLPDDLMWNRGDAALTQMANVAEASGGSVIAVEDVPHDKTASYGIVSTDA
HHHCCCCEEEEECCHHCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCEEECCC
FDGRKGRINAIVEKPKPEVAPSNLAVVGRYVLSPKIFDLLEATGAGAGGEIQLTDAIAEL
CCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHCHHHHHHHHHHCCCCCCEEEEHHHHHHH
LKEEQVDAFRFEGRRFDCGAHIGLIEATVHFALEHEKHGGPAKEILRNALAQADARG
HHHHCCHHHHCCCCEECCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA