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The map label for this gene is intZ [H]

Identifier: 78048040

GI number: 78048040

Start: 2802474

End: 2803676

Strand: Reverse

Name: intZ [H]

Synonym: XCV2484

Alternate gene names: 78048040

Gene position: 2803676-2802474 (Counterclockwise)

Preceding gene: 78048041

Following gene: 78048037

Centisome position: 54.14

GC content: 62.84

Gene sequence:

>1203_bases
ATGCTGACCGATACCAAGCTGCGCAACCTCAAGCCGAAGGACAAGCTCTACAAGGTGAATGACCGTGACGGCCTCTATGT
AGCCGTCACGGCTGCCGGAGCGATCTCATTCCGCTACAACTACTCGATCCACGGTAGGCAGGAGACCATCACCTTCGGCC
GCTACGGTGTCGGCGGCATCACCCTGGCGGAAGCCCGCGAGCGGTTGGGCGAGGCCAAGAAGATGGTTGCGGCCGGGAAG
TCACCGGCCAAGGAGAAGGCGCGGGATAAGGCCCGCGTCAAGGGCGCGGAGACGTTCGGGGCCTGGGCGGAAAAGTGGCT
GCGCGGCTACCAAATGGCCGACTCCACCCGCGACATGCGCCGCTCAGTCTACGAGCGCGACTTGAAACCGAAATTCGGCA
ATCAGAAGCTGGTGGAGATTACCCACGAGGACTTGCGGGCACTGACCGATGCCATCGTGGAGCGCGGCGCGCCGGCAACG
GCAGTGCATGTCCGCGAGGTGGTGATGCAGGTCTATCGCTGGGCCATCGAGCGTGGCCAGAAGGTCGAGAACCCGGCGGA
GCTGGTGCGCCCAACGTCCATCGCCAAATTCGAGCCGCGCGACCGTGCGCTGACGCCCGACGAGATCGGCCTGATGTACC
AGTACATGGAGCGCATTGGCACAGCTCCATCCATTCGGGCGGCGGCCAAGCTGCTGCTGTTGACAATGGTGCGCAAGAGC
GAGCTGACCAACGCGACCTGGAGCGAGATCAATTTCAGCGACGCACTCTTGACGATCCCGAAGGAGCGGATGAAGCGGCG
CAATCCGCACCTGGTGTTTCTGTCCCGCCAGGCGCTGGACATCTTCATTGCCCTGAAAACCTTCGCCGGTGGATCGGACT
ACGTGCTGCCGTCGCGGTACGACTCGGACCTACCCATGAGCAGCGCTACGCTCAACCAGGTGCTGACGCTGACGTATCGG
CTGGCGCAGAAGGAAGGAAAGCCGCTCGCCAAGTTCGGGCCGCATGACTTGCGGCGCACGGCCAGCACGTTGTTGCACGA
GGCTGGCTACAACACGGACTGGATCGAGAAGTGTCTGGCGCACGAACAGAGAGGCGTCAGGGCCGTCTACAACAAGGCCG
AGTACCGCGAGCAGCGGACGGCGATGTTGCAGGACTGGGCGGACATGATCGACGAATGGACGCTCAAGCGGTCGAAGGCT
TAA

Upstream 100 bases:

>100_bases
GGTATTGAATTGGCGTAAAACAATGATTTTGTTGTTTTTTTTACGCCAGGATAGACCGATTTTCGGATCATGGTATTTGA
GCTGAATCAGGGCGAGAACC

Downstream 100 bases:

>100_bases
GTCAGAGGAGGGCAGGTAGGCAGCGCCTCCAGAACAGCGACCTTGGCCTCGGCTGTCATTGACACTTGAGGGGCGCGGCG
TTTTAGCGGCTAAAAAGCGG

Product: phage-related integrase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 400; Mature: 400

Protein sequence:

>400_residues
MLTDTKLRNLKPKDKLYKVNDRDGLYVAVTAAGAISFRYNYSIHGRQETITFGRYGVGGITLAEARERLGEAKKMVAAGK
SPAKEKARDKARVKGAETFGAWAEKWLRGYQMADSTRDMRRSVYERDLKPKFGNQKLVEITHEDLRALTDAIVERGAPAT
AVHVREVVMQVYRWAIERGQKVENPAELVRPTSIAKFEPRDRALTPDEIGLMYQYMERIGTAPSIRAAAKLLLLTMVRKS
ELTNATWSEINFSDALLTIPKERMKRRNPHLVFLSRQALDIFIALKTFAGGSDYVLPSRYDSDLPMSSATLNQVLTLTYR
LAQKEGKPLAKFGPHDLRRTASTLLHEAGYNTDWIEKCLAHEQRGVRAVYNKAEYREQRTAMLQDWADMIDEWTLKRSKA

Sequences:

>Translated_400_residues
MLTDTKLRNLKPKDKLYKVNDRDGLYVAVTAAGAISFRYNYSIHGRQETITFGRYGVGGITLAEARERLGEAKKMVAAGK
SPAKEKARDKARVKGAETFGAWAEKWLRGYQMADSTRDMRRSVYERDLKPKFGNQKLVEITHEDLRALTDAIVERGAPAT
AVHVREVVMQVYRWAIERGQKVENPAELVRPTSIAKFEPRDRALTPDEIGLMYQYMERIGTAPSIRAAAKLLLLTMVRKS
ELTNATWSEINFSDALLTIPKERMKRRNPHLVFLSRQALDIFIALKTFAGGSDYVLPSRYDSDLPMSSATLNQVLTLTYR
LAQKEGKPLAKFGPHDLRRTASTLLHEAGYNTDWIEKCLAHEQRGVRAVYNKAEYREQRTAMLQDWADMIDEWTLKRSKA
>Mature_400_residues
MLTDTKLRNLKPKDKLYKVNDRDGLYVAVTAAGAISFRYNYSIHGRQETITFGRYGVGGITLAEARERLGEAKKMVAAGK
SPAKEKARDKARVKGAETFGAWAEKWLRGYQMADSTRDMRRSVYERDLKPKFGNQKLVEITHEDLRALTDAIVERGAPAT
AVHVREVVMQVYRWAIERGQKVENPAELVRPTSIAKFEPRDRALTPDEIGLMYQYMERIGTAPSIRAAAKLLLLTMVRKS
ELTNATWSEINFSDALLTIPKERMKRRNPHLVFLSRQALDIFIALKTFAGGSDYVLPSRYDSDLPMSSATLNQVLTLTYR
LAQKEGKPLAKFGPHDLRRTASTLLHEAGYNTDWIEKCLAHEQRGVRAVYNKAEYREQRTAMLQDWADMIDEWTLKRSKA

Specific function: Integrase is necessary for integration of the phage into the host genome by site-specific recombination. In conjunction with excisionase, integrase is also necessary for excision of the prophage from the host genome [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family [H]

Homologues:

Organism=Escherichia coli, GI145693166, Length=399, Percent_Identity=35.8395989974937, Blast_Score=196, Evalue=2e-51,
Organism=Escherichia coli, GI1788974, Length=403, Percent_Identity=32.0099255583127, Blast_Score=165, Evalue=4e-42,
Organism=Escherichia coli, GI1788690, Length=399, Percent_Identity=28.0701754385965, Blast_Score=144, Evalue=1e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR023109 [H]

Pfam domain/function: PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 45545; Mature: 45545

Theoretical pI: Translated: 10.24; Mature: 10.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTDTKLRNLKPKDKLYKVNDRDGLYVAVTAAGAISFRYNYSIHGRQETITFGRYGVGGI
CCCCCCHHCCCCHHHEEEECCCCCEEEEEEECCEEEEEEEEEECCCCEEEEECCCCCCCE
TLAEARERLGEAKKMVAAGKSPAKEKARDKARVKGAETFGAWAEKWLRGYQMADSTRDMR
EHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
RSVYERDLKPKFGNQKLVEITHEDLRALTDAIVERGAPATAVHVREVVMQVYRWAIERGQ
HHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCC
KVENPAELVRPTSIAKFEPRDRALTPDEIGLMYQYMERIGTAPSIRAAAKLLLLTMVRKS
CCCCHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
ELTNATWSEINFSDALLTIPKERMKRRNPHLVFLSRQALDIFIALKTFAGGSDYVLPSRY
HCCCCCHHHCCCCHHHEECCHHHHHCCCCCEEEEEHHHHHHHHHHHHHCCCCCCCCCCCC
DSDLPMSSATLNQVLTLTYRLAQKEGKPLAKFGPHDLRRTASTLLHEAGYNTDWIEKCLA
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHH
HEQRGVRAVYNKAEYREQRTAMLQDWADMIDEWTLKRSKA
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLTDTKLRNLKPKDKLYKVNDRDGLYVAVTAAGAISFRYNYSIHGRQETITFGRYGVGGI
CCCCCCHHCCCCHHHEEEECCCCCEEEEEEECCEEEEEEEEEECCCCEEEEECCCCCCCE
TLAEARERLGEAKKMVAAGKSPAKEKARDKARVKGAETFGAWAEKWLRGYQMADSTRDMR
EHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
RSVYERDLKPKFGNQKLVEITHEDLRALTDAIVERGAPATAVHVREVVMQVYRWAIERGQ
HHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCC
KVENPAELVRPTSIAKFEPRDRALTPDEIGLMYQYMERIGTAPSIRAAAKLLLLTMVRKS
CCCCHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
ELTNATWSEINFSDALLTIPKERMKRRNPHLVFLSRQALDIFIALKTFAGGSDYVLPSRY
HCCCCCHHHCCCCHHHEECCHHHHHCCCCCEEEEEHHHHHHHHHHHHHCCCCCCCCCCCC
DSDLPMSSATLNQVLTLTYRLAQKEGKPLAKFGPHDLRRTASTLLHEAGYNTDWIEKCLA
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHH
HEQRGVRAVYNKAEYREQRTAMLQDWADMIDEWTLKRSKA
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]