| Definition | Xanthomonas campestris pv. vesicatoria str. 85-10 chromosome, complete genome. |
|---|---|
| Accession | NC_007508 |
| Length | 5,178,466 |
Click here to switch to the map view.
The map label for this gene is topB2 [H]
Identifier: 78047962
GI number: 78047962
Start: 2730083
End: 2732095
Strand: Reverse
Name: topB2 [H]
Synonym: XCV2406
Alternate gene names: 78047962
Gene position: 2732095-2730083 (Counterclockwise)
Preceding gene: 78047963
Following gene: 78047961
Centisome position: 52.76
GC content: 66.47
Gene sequence:
>2013_bases ATGCGGCTGTTCTTGTGCGAGAAGCCCTCCCAGGGCAAAGACATTGGCCGGATTCTCGGCGCGACGCAGCGCGGTGAAGG CTGTCTCAGCGGCTCTGGCGTCACCGTTACCTGGTGCATCGGCCATCTCGTAGAAGCGGCAGCTCCCGAGGTCTATGACG CGGCGCTCAAGCGCTGGTCGCTGGAGCAGTTGCCCATTGTTCCGCAGCAGTGGCGGGTCGAGGTCAAACCGAAGACCGCC ACGCAATTCAAGGTCGTCAAGGCGCTTCTGGCGAAGGCGACCCATCTGGTCATCGCCACCGATGCCGACCGTGAGGGCGA GCTGATCGCCCGCGAGATCATCGACCTGTGCGGCTACCGCGGCCCCATCGAGCGGCTATGGTTGTCGGCGCTCAACGATG CGTCGATCCGCACCGCGCTCGGCAAGTTGCGGCCCTCATCCGACACGCTGCCGATGTACTACTCGGCGCTTGCGCGCTCA CGCGCCGACTGGCTCGTGGGCATGAACCTCAGCCGGTTGTTCACGGTGCTCGGGCGTCAGGCCGGCTACGACGGCGTGCT GTCCGTCGGTCGCGTCCAGACGCCGACCTTGAAGCTCGTCGTGGACCGCGACCGCGAGATCGCGGCCTTCAAGTCGGTGC CGTTCTGGGCCATCGACGTGTCCCTGTCCGCAGGTGGACAGGCTTTCAGCGCGCAGTGGGTTCCGCCCGATGGCTGCACC GACGATGCCGGCCGCTGCCTGCAGCAGCCTATCGCCCAGCAGGCCGCGCAGCAGATCCGCGCTGCGAGCAGCGCCCAGGT CGTGTCAGTCGAGACCGAGCGCGTGCGCGAAGGGCCACCGCTGCTGTTCGACCTGGGAACGCTTCAGGAGGTTTGTTCCA AGCAGCTTGGGCTGGATGTGCAGGAGACGCTGGAGATCGCCCAGGCCCTGTATGAGACCCATAAAGCCACCACGTACCCG CGTTCCGATTCGGGCTACCTGCCCGAAAGCATGTTCGCCGAGGTGCCGACTGTTCTGGACAGCCTGCTCAAGACCGACCC CTCGCTGCGCCCGATCATGGGCCAGCTCGACCGCTCCCAGCGCTCGCGCGCCTGGAACGACGGCAAAGTGACGGCGCACC ACGGCATCATTCCCACCTTGGAACCCGCGAACCTCTCGGCTATGAGCGAGAAGGAACTGGCGGTGTACTGGCTGATCCGC GCGCATTACCTGGCGCAGTTCCTCCCTCACCACGAGTTCGACCGCACGATCGCCGAGCTGTCCTGCGGCCAGCAGAAGCT GGTGGCCACCGGAAAGCAGGTGGCCGCCCAGGGTTGGCACCTGGTGCTGGCCGAGCCGCAAGCGGACGAGGACGGGGAAA CCACCGCGCGCAGCCAGGTACTCCCCGCGCTGCGCGAGGGCCTGGCATGCCAAGTGGCCGAGGCCGAAGTCAAGGCGCTC AAGACGCTGCCTCCGAAGCCCTACACGCAGGGCGAACTGGTCAAGTCGATGAAAGGCGTGGCGCGCTTCGTGACCGACCC GCGCCTGAAGCAGAAGTTGAAGGACACGACGGGCATTGGCACCGAAGCCACGCGCGCCAACATCATCACCGGCCTGCTGA CGCGGGGCTATCTCGTGAAGAAAGGACGCTCCATTCGCGCATCGGATGCGGCATTCACGCTGATCGACGCTGTGCCCGCG GCGATTGCCGACCCCGGAACCACCGCCGTGTGGGAGCAGGCGCTCGACATGATCGAGGCCGGACAGCTCACCCTGGATGT GTTCATCGGCAAGCAGGCCGCATGGATTTCGCAACTGATCGTGCAGTACGGCAGCACCTCGCTGTCCATCAAGGTTCCCC AGGGTCCCGCTTGCCCGCAGTGCGGCGCACCGACGCGCCAGCGCACCGGCAAGACCGGCCCCTTCTGGTCGTGCAGTCGC TACCCCGACTGCAAAGGCACGCTGCCGGTCGATTCCGGCACGTCCAAGCGCGGTGCCTCGCGCCCGCGCAGTAGCGGCCG CAAGGGCTCCTGA
Upstream 100 bases:
>100_bases TGGTCGCCACCGCATGCGGCTTGTTTGCTGCTGCCCCTGGTGGTGCTCGGCATCCTCGATTCCAGCAACTCAATGAACCA CGGAAATCGGATGGACGGAC
Downstream 100 bases:
>100_bases CCGACCCCGCTCCCCGAGAGCCGTGCCCGCCATCGGCGGCGTGGCCCATGTCCCGCACGCCCTGCGGGACGCCCAGCGCG CAACGCCTTCTCTTGTCCGT
Product: DNA topoisomerase III
Products: NA
Alternate protein names: DNA topoisomerase III [H]
Number of amino acids: Translated: 670; Mature: 670
Protein sequence:
>670_residues MRLFLCEKPSQGKDIGRILGATQRGEGCLSGSGVTVTWCIGHLVEAAAPEVYDAALKRWSLEQLPIVPQQWRVEVKPKTA TQFKVVKALLAKATHLVIATDADREGELIAREIIDLCGYRGPIERLWLSALNDASIRTALGKLRPSSDTLPMYYSALARS RADWLVGMNLSRLFTVLGRQAGYDGVLSVGRVQTPTLKLVVDRDREIAAFKSVPFWAIDVSLSAGGQAFSAQWVPPDGCT DDAGRCLQQPIAQQAAQQIRAASSAQVVSVETERVREGPPLLFDLGTLQEVCSKQLGLDVQETLEIAQALYETHKATTYP RSDSGYLPESMFAEVPTVLDSLLKTDPSLRPIMGQLDRSQRSRAWNDGKVTAHHGIIPTLEPANLSAMSEKELAVYWLIR AHYLAQFLPHHEFDRTIAELSCGQQKLVATGKQVAAQGWHLVLAEPQADEDGETTARSQVLPALREGLACQVAEAEVKAL KTLPPKPYTQGELVKSMKGVARFVTDPRLKQKLKDTTGIGTEATRANIITGLLTRGYLVKKGRSIRASDAAFTLIDAVPA AIADPGTTAVWEQALDMIEAGQLTLDVFIGKQAAWISQLIVQYGSTSLSIKVPQGPACPQCGAPTRQRTGKTGPFWSCSR YPDCKGTLPVDSGTSKRGASRPRSSGRKGS
Sequences:
>Translated_670_residues MRLFLCEKPSQGKDIGRILGATQRGEGCLSGSGVTVTWCIGHLVEAAAPEVYDAALKRWSLEQLPIVPQQWRVEVKPKTA TQFKVVKALLAKATHLVIATDADREGELIAREIIDLCGYRGPIERLWLSALNDASIRTALGKLRPSSDTLPMYYSALARS RADWLVGMNLSRLFTVLGRQAGYDGVLSVGRVQTPTLKLVVDRDREIAAFKSVPFWAIDVSLSAGGQAFSAQWVPPDGCT DDAGRCLQQPIAQQAAQQIRAASSAQVVSVETERVREGPPLLFDLGTLQEVCSKQLGLDVQETLEIAQALYETHKATTYP RSDSGYLPESMFAEVPTVLDSLLKTDPSLRPIMGQLDRSQRSRAWNDGKVTAHHGIIPTLEPANLSAMSEKELAVYWLIR AHYLAQFLPHHEFDRTIAELSCGQQKLVATGKQVAAQGWHLVLAEPQADEDGETTARSQVLPALREGLACQVAEAEVKAL KTLPPKPYTQGELVKSMKGVARFVTDPRLKQKLKDTTGIGTEATRANIITGLLTRGYLVKKGRSIRASDAAFTLIDAVPA AIADPGTTAVWEQALDMIEAGQLTLDVFIGKQAAWISQLIVQYGSTSLSIKVPQGPACPQCGAPTRQRTGKTGPFWSCSR YPDCKGTLPVDSGTSKRGASRPRSSGRKGS >Mature_670_residues MRLFLCEKPSQGKDIGRILGATQRGEGCLSGSGVTVTWCIGHLVEAAAPEVYDAALKRWSLEQLPIVPQQWRVEVKPKTA TQFKVVKALLAKATHLVIATDADREGELIAREIIDLCGYRGPIERLWLSALNDASIRTALGKLRPSSDTLPMYYSALARS RADWLVGMNLSRLFTVLGRQAGYDGVLSVGRVQTPTLKLVVDRDREIAAFKSVPFWAIDVSLSAGGQAFSAQWVPPDGCT DDAGRCLQQPIAQQAAQQIRAASSAQVVSVETERVREGPPLLFDLGTLQEVCSKQLGLDVQETLEIAQALYETHKATTYP RSDSGYLPESMFAEVPTVLDSLLKTDPSLRPIMGQLDRSQRSRAWNDGKVTAHHGIIPTLEPANLSAMSEKELAVYWLIR AHYLAQFLPHHEFDRTIAELSCGQQKLVATGKQVAAQGWHLVLAEPQADEDGETTARSQVLPALREGLACQVAEAEVKAL KTLPPKPYTQGELVKSMKGVARFVTDPRLKQKLKDTTGIGTEATRANIITGLLTRGYLVKKGRSIRASDAAFTLIDAVPA AIADPGTTAVWEQALDMIEAGQLTLDVFIGKQAAWISQLIVQYGSTSLSIKVPQGPACPQCGAPTRQRTGKTGPFWSCSR YPDCKGTLPVDSGTSKRGASRPRSSGRKGS
Specific function: The reaction catalyzed by topoisomerases leads to the conversion of one topological isomer of DNA to another. TOP3 is a potent decatenase [H]
COG id: COG0550
COG function: function code L; Topoisomerase IA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 Toprim domain [H]
Homologues:
Organism=Homo sapiens, GI10835218, Length=712, Percent_Identity=24.7191011235955, Blast_Score=120, Evalue=4e-27, Organism=Homo sapiens, GI4507635, Length=671, Percent_Identity=22.354694485842, Blast_Score=108, Evalue=1e-23, Organism=Escherichia coli, GI1788061, Length=651, Percent_Identity=39.7849462365591, Blast_Score=453, Evalue=1e-128, Organism=Escherichia coli, GI1787529, Length=691, Percent_Identity=26.6280752532561, Blast_Score=146, Evalue=4e-36, Organism=Caenorhabditis elegans, GI32563869, Length=572, Percent_Identity=25, Blast_Score=141, Evalue=1e-33, Organism=Caenorhabditis elegans, GI17555378, Length=664, Percent_Identity=23.644578313253, Blast_Score=112, Evalue=8e-25, Organism=Drosophila melanogaster, GI24585251, Length=726, Percent_Identity=24.2424242424242, Blast_Score=119, Evalue=5e-27, Organism=Drosophila melanogaster, GI24640096, Length=531, Percent_Identity=23.3521657250471, Blast_Score=108, Evalue=1e-23,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003601 - InterPro: IPR013497 - InterPro: IPR013824 - InterPro: IPR013825 - InterPro: IPR000380 - InterPro: IPR003602 - InterPro: IPR005738 - InterPro: IPR006171 [H]
Pfam domain/function: PF01131 Topoisom_bac; PF01751 Toprim [H]
EC number: =5.99.1.2 [H]
Molecular weight: Translated: 72725; Mature: 72725
Theoretical pI: Translated: 8.67; Mature: 8.67
Prosite motif: PS00396 TOPOISOMERASE_I_PROK
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.9 %Cys (Translated Protein) 1.2 %Met (Translated Protein) 3.1 %Cys+Met (Translated Protein) 1.9 %Cys (Mature Protein) 1.2 %Met (Mature Protein) 3.1 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MRLFLCEKPSQGKDIGRILGATQRGEGCLSGSGVTVTWCIGHLVEAAAPEVYDAALKRWS CEEEEECCCCCCCHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHCC LEQLPIVPQQWRVEVKPKTATQFKVVKALLAKATHLVIATDADREGELIAREIIDLCGYR HHHCCCCCHHCEEEECCCCHHHHHHHHHHHHHHCEEEEEECCCCCCHHHHHHHHHHHCCC GPIERLWLSALNDASIRTALGKLRPSSDTLPMYYSALARSRADWLVGMNLSRLFTVLGRQ CHHHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHCHHEECCCHHHHHHHHHHC AGYDGVLSVGRVQTPTLKLVVDRDREIAAFKSVPFWAIDVSLSAGGQAFSAQWVPPDGCT CCCCHHHCCCCCCCCEEEEEECCCCCCHHHCCCCEEEEEEEECCCCCEEECCCCCCCCCC DDAGRCLQQPIAQQAAQQIRAASSAQVVSVETERVREGPPLLFDLGTLQEVCSKQLGLDV CHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHCCCCEEEEHHHHHHHHHHHHCCCH QETLEIAQALYETHKATTYPRSDSGYLPESMFAEVPTVLDSLLKTDPSLRPIMGQLDRSQ HHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH RSRAWNDGKVTAHHGIIPTLEPANLSAMSEKELAVYWLIRAHYLAQFLPHHEFDRTIAEL HHCCCCCCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHH SCGQQKLVATGKQVAAQGWHLVLAEPQADEDGETTARSQVLPALREGLACQVAEAEVKAL HCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHHHCCCEEEHHHHHHHHH KTLPPKPYTQGELVKSMKGVARFVTDPRLKQKLKDTTGIGTEATRANIITGLLTRGYLVK HCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCHHHH KGRSIRASDAAFTLIDAVPAAIADPGTTAVWEQALDMIEAGQLTLDVFIGKQAAWISQLI CCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHH VQYGSTSLSIKVPQGPACPQCGAPTRQRTGKTGPFWSCSRYPDCKGTLPVDSGTSKRGAS HHHCCCEEEEECCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC RPRSSGRKGS CCCCCCCCCC >Mature Secondary Structure MRLFLCEKPSQGKDIGRILGATQRGEGCLSGSGVTVTWCIGHLVEAAAPEVYDAALKRWS CEEEEECCCCCCCHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHCC LEQLPIVPQQWRVEVKPKTATQFKVVKALLAKATHLVIATDADREGELIAREIIDLCGYR HHHCCCCCHHCEEEECCCCHHHHHHHHHHHHHHCEEEEEECCCCCCHHHHHHHHHHHCCC GPIERLWLSALNDASIRTALGKLRPSSDTLPMYYSALARSRADWLVGMNLSRLFTVLGRQ CHHHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHCHHEECCCHHHHHHHHHHC AGYDGVLSVGRVQTPTLKLVVDRDREIAAFKSVPFWAIDVSLSAGGQAFSAQWVPPDGCT CCCCHHHCCCCCCCCEEEEEECCCCCCHHHCCCCEEEEEEEECCCCCEEECCCCCCCCCC DDAGRCLQQPIAQQAAQQIRAASSAQVVSVETERVREGPPLLFDLGTLQEVCSKQLGLDV CHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHCCCCEEEEHHHHHHHHHHHHCCCH QETLEIAQALYETHKATTYPRSDSGYLPESMFAEVPTVLDSLLKTDPSLRPIMGQLDRSQ HHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH RSRAWNDGKVTAHHGIIPTLEPANLSAMSEKELAVYWLIRAHYLAQFLPHHEFDRTIAEL HHCCCCCCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHH SCGQQKLVATGKQVAAQGWHLVLAEPQADEDGETTARSQVLPALREGLACQVAEAEVKAL HCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHHHHHHCCCEEEHHHHHHHHH KTLPPKPYTQGELVKSMKGVARFVTDPRLKQKLKDTTGIGTEATRANIITGLLTRGYLVK HCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCHHHH KGRSIRASDAAFTLIDAVPAAIADPGTTAVWEQALDMIEAGQLTLDVFIGKQAAWISQLI CCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHH VQYGSTSLSIKVPQGPACPQCGAPTRQRTGKTGPFWSCSRYPDCKGTLPVDSGTSKRGAS HHHCCCEEEEECCCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC RPRSSGRKGS CCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 2553698; 9097039; 9278503; 10574789 [H]