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The map label for this gene is strB [H]

Identifier: 78047881

GI number: 78047881

Start: 2656581

End: 2657426

Strand: Reverse

Name: strB [H]

Synonym: XCV2325

Alternate gene names: 78047881

Gene position: 2657426-2656581 (Counterclockwise)

Preceding gene: 78047882

Following gene: 78047880

Centisome position: 51.32

GC content: 55.91

Gene sequence:

>846_bases
TTGGGGTTGATGTTCATGCCGCCTGTTTTTCCTGCTCATTGGCACGTTTCGCAACCTGTTCTCATTGCGGACACCTTTTC
CAGCCTCGTTTGGAAAGTTTCATTGCCAGACGGGACTCCTGCAATCGTCAAGGGATTGAAACCTATAGAAGACATTGCTG
ATGAACTGCGCGGGGCCGACTATCTGGTATGGCGCAATGGGAGGGGAGCAGTCCGGTTGCTCGGTCGTGAGAACAATCTG
ATGTTGCTCGAATATGCCGGGGAGCGAATGCTCTCTCACATCGTTGCCGAGCACGGCGACTACCAGGCGACCGAAATTGC
AGCGGAACTAATGGCGAAGCTGTATGCCGCATCTGAGGAACCCCTGCCTTCTGCCCTTCTCCCGATCCGGGATCGCTTTG
CAGCTTTGTTTCAGCGGGCGCGCGATGATCAAAACGCAGGTTGTCAAACTGACTACGTCCACGCGGCGATTATAGCCGAT
CAAATGATGAGCAATGCCTCGGAACTGCGTGGGCTACATGGCGATCTGCATCATGAAAACATCATGTTCTCCAGTCGCGG
CTGGCTGGTGATAGATCCCGTCGGTCTGGTCGGTGAAGTGGGCTTTGGCGCCGCCAATATGTTCTACGATCCGGCTGACA
GAGACGACCTTTGTCTCGATCCTAGACGCATTGCACAGATGGCGGACGCATTCTCTCGTGCGCTGGACGTCGATCCGCGT
CGCCTGCTCGACCAGGCGTACGCTTATGGGTGCCTTTCCGCAGCTTGGAACGCGGATGGAGAAGAGGAGCAACGCGATCT
AGCTATCGCGGCCGCGATCAAGCAGGTGCGACAGACGTCATACTAG

Upstream 100 bases:

>100_bases
ATGAAGCAGAGCGCGCCTTCGCTGTCCTATTCAATGTATTGGGGATCGAAGCCCCCGACCGCGAACGCCTTGCCTTCTAT
CTGCGATTGGACCCTCTGAC

Downstream 100 bases:

>100_bases
ATATCAAGCGACTTCTCCTATCCCCTGGGAACACATCAATCTTACCGGAGAATATCGTTGGCCAAAGCCTTAGCGTAGGA
TTTCGCCCTCTCCCGCAAAC

Product: streptomycin 3''-kinase

Products: NA

Alternate protein names: Streptomycin 3''-phosphotransferase; SPH [H]

Number of amino acids: Translated: 281; Mature: 280

Protein sequence:

>281_residues
MGLMFMPPVFPAHWHVSQPVLIADTFSSLVWKVSLPDGTPAIVKGLKPIEDIADELRGADYLVWRNGRGAVRLLGRENNL
MLLEYAGERMLSHIVAEHGDYQATEIAAELMAKLYAASEEPLPSALLPIRDRFAALFQRARDDQNAGCQTDYVHAAIIAD
QMMSNASELRGLHGDLHHENIMFSSRGWLVIDPVGLVGEVGFGAANMFYDPADRDDLCLDPRRIAQMADAFSRALDVDPR
RLLDQAYAYGCLSAAWNADGEEEQRDLAIAAAIKQVRQTSY

Sequences:

>Translated_281_residues
MGLMFMPPVFPAHWHVSQPVLIADTFSSLVWKVSLPDGTPAIVKGLKPIEDIADELRGADYLVWRNGRGAVRLLGRENNL
MLLEYAGERMLSHIVAEHGDYQATEIAAELMAKLYAASEEPLPSALLPIRDRFAALFQRARDDQNAGCQTDYVHAAIIAD
QMMSNASELRGLHGDLHHENIMFSSRGWLVIDPVGLVGEVGFGAANMFYDPADRDDLCLDPRRIAQMADAFSRALDVDPR
RLLDQAYAYGCLSAAWNADGEEEQRDLAIAAAIKQVRQTSY
>Mature_280_residues
GLMFMPPVFPAHWHVSQPVLIADTFSSLVWKVSLPDGTPAIVKGLKPIEDIADELRGADYLVWRNGRGAVRLLGRENNLM
LLEYAGERMLSHIVAEHGDYQATEIAAELMAKLYAASEEPLPSALLPIRDRFAALFQRARDDQNAGCQTDYVHAAIIADQ
MMSNASELRGLHGDLHHENIMFSSRGWLVIDPVGLVGEVGFGAANMFYDPADRDDLCLDPRRIAQMADAFSRALDVDPRR
LLDQAYAYGCLSAAWNADGEEEQRDLAIAAAIKQVRQTSY

Specific function: The aminoglycoside phosphotransferases achieve inactivation of their antibiotic substrates by phosphorylation [H]

COG id: COG3570

COG function: function code V; Streptomycin 6-kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aminoglycoside phosphotransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006748 [H]

Pfam domain/function: PF04655 APH_6_hur [H]

EC number: =2.7.1.87 [H]

Molecular weight: Translated: 31126; Mature: 30995

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLMFMPPVFPAHWHVSQPVLIADTFSSLVWKVSLPDGTPAIVKGLKPIEDIADELRGAD
CCCCCCCCCCCCCCCCCCCEEEHCCHHHHEEEEECCCCCHHHHHCCCHHHHHHHHHCCCC
YLVWRNGRGAVRLLGRENNLMLLEYAGERMLSHIVAEHGDYQATEIAAELMAKLYAASEE
EEEEECCCCEEEEEECCCCEEEEEHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCC
PLPSALLPIRDRFAALFQRARDDQNAGCQTDYVHAAIIADQMMSNASELRGLHGDLHHEN
CCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCHHHHHHCCCCCCCCC
IMFSSRGWLVIDPVGLVGEVGFGAANMFYDPADRDDLCLDPRRIAQMADAFSRALDVDPR
EEEECCCCEEECCCHHHHHCCCCHHHCEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCHH
RLLDQAYAYGCLSAAWNADGEEEQRDLAIAAAIKQVRQTSY
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
GLMFMPPVFPAHWHVSQPVLIADTFSSLVWKVSLPDGTPAIVKGLKPIEDIADELRGAD
CCCCCCCCCCCCCCCCCCEEEHCCHHHHEEEEECCCCCHHHHHCCCHHHHHHHHHCCCC
YLVWRNGRGAVRLLGRENNLMLLEYAGERMLSHIVAEHGDYQATEIAAELMAKLYAASEE
EEEEECCCCEEEEEECCCCEEEEEHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCC
PLPSALLPIRDRFAALFQRARDDQNAGCQTDYVHAAIIADQMMSNASELRGLHGDLHHEN
CCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCHHHHHHCCCCCCCCC
IMFSSRGWLVIDPVGLVGEVGFGAANMFYDPADRDDLCLDPRRIAQMADAFSRALDVDPR
EEEECCCCEEECCCHHHHHCCCCHHHCEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCHH
RLLDQAYAYGCLSAAWNADGEEEQRDLAIAAAIKQVRQTSY
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3889831 [H]