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The map label for this gene is trxB2 [H]

Identifier: 78047867

GI number: 78047867

Start: 2644801

End: 2645760

Strand: Reverse

Name: trxB2 [H]

Synonym: XCV2311

Alternate gene names: 78047867

Gene position: 2645760-2644801 (Counterclockwise)

Preceding gene: 78047868

Following gene: 78047864

Centisome position: 51.09

GC content: 66.67

Gene sequence:

>960_bases
ATGACCATGGCAACACACCATCAGCTCATCATTCTCGGCTCCGGGCCGGCCGGCTGGACCGCCGCGGTCTACGCCGCCCG
TGCCAACCTCAAGCCATTGGTTCTCACCGGCCTGCAAATGGGCGGCCAGCTCATGACCACCACCGAGGTGGACAACTGGC
CGGGCGATGCCCATGGGCTGATGGGGCCGGACCTGATGACGCGCATGCAGGCCCATGCCGAGCGCTTCGAGACCGAGGTG
GTATTCGACCACATCCACACCGCCGATCTGTCCAAGCGCCCGTTCACCCTGACCGGCGACAGCGCGCAGTACACCTGCGA
CGCGCTGATCATCGCCACCGGCGCCACCGCCAAGTACCTGGGCATTCCGTCCGAGGAGGCGTTCAAGGGCCGCGGCGTCT
CGGCCTGCGCCACCTGCGACGGCTTCTTCTACAAGGACCAGGACGTGATCGTGGTCGGCGGCGGCAACACCGCGGTCGAG
GAGGCCCTGTACCTGTCCAACATCGCCCGCAAGGTCTACCTGGTGCACCGCCGCGACACCCTGCGCGCGGAGAAGATCAT
GCAGGACAAGCTGTTCGCCAAGGTCGCCGCCGGCAAGGTCGAGACCGTCTGGCACCACGAGGTGGACGAGGTGCTGGGCA
ACGACATGGGCGTGACCGGGGTGCGGGTGAAGTCCACCCTGGACGGCAGCACCCGCGACATCGACGCCCACGGCTTCTTC
GTCGCTATCGGCCACAGCCCGAACACCGAGCTGTTCAAGGGCCAGTTGGCGATGAACAACGGCTACCTGGAAATCCGTTC
CGGCTTGGGCGGCAACGCCACCCAGACCTCGGTGGAAGGCGTGTTCGCCGCCGGCGACGTGGCCGACCAGCACTACCGTC
AGGCCATTACCTCGGCCGGCTTCGGCTGCATGGCGGCACTGGACGCGGAGCGATTCCTCGACTCGGCCGTTGTCCGATAA

Upstream 100 bases:

>100_bases
TCGCGACGGTCGCCGCCTACAACATGGTGTCCCGCTTCTTGGTCGCCCTTGCGATCTGAGCATGCCGACCCGCCTTCCAA
TTGATCAACCGACACTCATC

Downstream 100 bases:

>100_bases
GGAACGCGCCATGGCCGGATGGAGAGGCAGGCGATCAACCCCTTGCATCGAGGCATCGAGCCTCTATCCAGGGAAAGTGC
TGTCCCTCGGTGCGTTTGTT

Product: thioredoxin reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 319; Mature: 318

Protein sequence:

>319_residues
MTMATHHQLIILGSGPAGWTAAVYAARANLKPLVLTGLQMGGQLMTTTEVDNWPGDAHGLMGPDLMTRMQAHAERFETEV
VFDHIHTADLSKRPFTLTGDSAQYTCDALIIATGATAKYLGIPSEEAFKGRGVSACATCDGFFYKDQDVIVVGGGNTAVE
EALYLSNIARKVYLVHRRDTLRAEKIMQDKLFAKVAAGKVETVWHHEVDEVLGNDMGVTGVRVKSTLDGSTRDIDAHGFF
VAIGHSPNTELFKGQLAMNNGYLEIRSGLGGNATQTSVEGVFAAGDVADQHYRQAITSAGFGCMAALDAERFLDSAVVR

Sequences:

>Translated_319_residues
MTMATHHQLIILGSGPAGWTAAVYAARANLKPLVLTGLQMGGQLMTTTEVDNWPGDAHGLMGPDLMTRMQAHAERFETEV
VFDHIHTADLSKRPFTLTGDSAQYTCDALIIATGATAKYLGIPSEEAFKGRGVSACATCDGFFYKDQDVIVVGGGNTAVE
EALYLSNIARKVYLVHRRDTLRAEKIMQDKLFAKVAAGKVETVWHHEVDEVLGNDMGVTGVRVKSTLDGSTRDIDAHGFF
VAIGHSPNTELFKGQLAMNNGYLEIRSGLGGNATQTSVEGVFAAGDVADQHYRQAITSAGFGCMAALDAERFLDSAVVR
>Mature_318_residues
TMATHHQLIILGSGPAGWTAAVYAARANLKPLVLTGLQMGGQLMTTTEVDNWPGDAHGLMGPDLMTRMQAHAERFETEVV
FDHIHTADLSKRPFTLTGDSAQYTCDALIIATGATAKYLGIPSEEAFKGRGVSACATCDGFFYKDQDVIVVGGGNTAVEE
ALYLSNIARKVYLVHRRDTLRAEKIMQDKLFAKVAAGKVETVWHHEVDEVLGNDMGVTGVRVKSTLDGSTRDIDAHGFFV
AIGHSPNTELFKGQLAMNNGYLEIRSGLGGNATQTSVEGVFAAGDVADQHYRQAITSAGFGCMAALDAERFLDSAVVR

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=315, Percent_Identity=65.3968253968254, Blast_Score=439, Evalue=1e-124,
Organism=Escherichia coli, GI87081763, Length=298, Percent_Identity=29.5302013422819, Blast_Score=132, Evalue=3e-32,
Organism=Saccharomyces cerevisiae, GI6320560, Length=322, Percent_Identity=42.5465838509317, Blast_Score=258, Evalue=7e-70,
Organism=Saccharomyces cerevisiae, GI6321898, Length=327, Percent_Identity=40.9785932721713, Blast_Score=253, Evalue=2e-68,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 34240; Mature: 34109

Theoretical pI: Translated: 5.91; Mature: 5.91

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTMATHHQLIILGSGPAGWTAAVYAARANLKPLVLTGLQMGGQLMTTTEVDNWPGDAHGL
CCCCCCEEEEEEECCCCCHHHHHHHHHCCCCEEEEEHHHCCCEEEEEEECCCCCCCCCCC
MGPDLMTRMQAHAERFETEVVFDHIHTADLSKRPFTLTGDSAQYTCDALIIATGATAKYL
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCEEEEEEEEEECCCEEEE
GIPSEEAFKGRGVSACATCDGFFYKDQDVIVVGGGNTAVEEALYLSNIARKVYLVHRRDT
CCCCHHHHCCCCCEEEEECCCCEECCCCEEEECCCCHHHHHHHHHHHHHHHEEEEECCHH
LRAEKIMQDKLFAKVAAGKVETVWHHEVDEVLGNDMGVTGVRVKSTLDGSTRDIDAHGFF
HHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHCCCCCCCEEEEEEECCCCCCEECCCEEE
VAIGHSPNTELFKGQLAMNNGYLEIRSGLGGNATQTSVEGVFAAGDVADQHYRQAITSAG
EEECCCCCCCCEEEEEEECCCEEEEECCCCCCCCCHHHCEEEEECCHHHHHHHHHHHHCC
FGCMAALDAERFLDSAVVR
CHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TMATHHQLIILGSGPAGWTAAVYAARANLKPLVLTGLQMGGQLMTTTEVDNWPGDAHGL
CCCCCEEEEEEECCCCCHHHHHHHHHCCCCEEEEEHHHCCCEEEEEEECCCCCCCCCCC
MGPDLMTRMQAHAERFETEVVFDHIHTADLSKRPFTLTGDSAQYTCDALIIATGATAKYL
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCEEEEEEEEEECCCEEEE
GIPSEEAFKGRGVSACATCDGFFYKDQDVIVVGGGNTAVEEALYLSNIARKVYLVHRRDT
CCCCHHHHCCCCCEEEEECCCCEECCCCEEEECCCCHHHHHHHHHHHHHHHEEEEECCHH
LRAEKIMQDKLFAKVAAGKVETVWHHEVDEVLGNDMGVTGVRVKSTLDGSTRDIDAHGFF
HHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHCCCCCCCEEEEEEECCCCCCEECCCEEE
VAIGHSPNTELFKGQLAMNNGYLEIRSGLGGNATQTSVEGVFAAGDVADQHYRQAITSAG
EEECCCCCCCCEEEEEEECCCEEEEECCCCCCCCCHHHCEEEEECCHHHHHHHHHHHHCC
FGCMAALDAERFLDSAVVR
CHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]