Click here to switch to the map view.

The map label for this gene is dsbD [H]

Identifier: 78047864

GI number: 78047864

Start: 2640729

End: 2642519

Strand: Reverse

Name: dsbD [H]

Synonym: XCV2308

Alternate gene names: 78047864

Gene position: 2642519-2640729 (Counterclockwise)

Preceding gene: 78047867

Following gene: 78047863

Centisome position: 51.03

GC content: 64.82

Gene sequence:

>1791_bases
ATGGTCGGCAGCGCCTGGGCGAATGGCCTTCTTCCCTCCTGGGGCAGTAGCGAACGGCAGTTTTTGGACGTTGCCGAAGT
ATTCAAGCTGGACCCAGCGCAGCAACAAGGCGACTCGTTCTTAATTGCAGGACATATCGCCGATGGCTACTACGTTTACC
GCCATGCCATCAAATTGGTCGATGCGCGGGGCCATGAGATCAGCCTGACCCTTCCAGCAGGAACTGCCAAGCACGACGAG
TTCTTTGGCGACACGGAAATCTATAAGGGTGATGCGCTCAATCTGCGCTTTCCCGTCACTGCCGCCGGCCCGCTGACACT
CCATTGGCAAGGGTGCGCCGAAGCAGGCATCTGCTATCCGCCGCAGACCGTGAACCTGGCACTGCCGGAAGTGGCAGCAG
GCACATCTACCGCAGGCAATGGCTCCACACACGAGAGCCCAACCGCGGCACCCGCCAGCCAAGGCAGCGTGGCGGGGGCG
ACCGAGATCGCCGAGGATCAAGCGGCAGCGCAGCGGCTTGCCGCACTCGGCCCCGTATGGGGAACGCTGCTGTTCTTCGG
CTTCGGGTTGCTGTTGGCCTTCACGCCATGCTCGCTGCCGATGATCCCCATCGTCTCCTCCATGGTCGTAGGCAGCCAAG
CCAAGCCGCGACGGGCCTTCTTCCTCTCGCTGTCCTATGTCGTGGCAATGGCGGGCACCTACGCGGTGGTGGGTGTGGCC
GCTGGCATGGCCGGTGCCAACCTGCAGGCCACCCTGCAATCGCCTTGGCTGCTGGGAGCGTTCGCGGCCCTGTTCCTCGT
CCTGGCGAGTTCGTTGTTCGGCCTGTTCGAGCTGCAGATGCCTTCGGCCCTGGTCAATCGTGTCGAGTCTGCCGGCAGAG
ACCGCTCGGGCGGCAGCATCCCCGGCGCTGCAGCACTGGGCTTCCTCTCGGCGCTCCTGGTCGGCCCCTGCATGACCGCG
CCATTGGCGGGTGCATTGCTGTACATCGGACAGACCGGCAGCGCGGTCTATGGCGGAATGGCATTGTTCGCGCTGGGTTT
GGGCATGGGATTGCCCCTGTTGGCCATCGCCGTGTTCGGTGCCCGGGTCCTACCTCGCCCGGGCGCATGGATGGATCGCG
TGCGCGTGGCATTCGGCTACGTCATGGTCGGCATGGCCGTGATGATGCTAACGCGCTTCCTGCCCGGCACCGTGGGCCTG
GTGCTTTGGGGGGCCTGGGTCTTGTCCGTGGCGATTGGCCTGATCGCCTGGGGTCAGGCCGTGGCGGCGAAGCATCGGCT
GGCATGGACGCTGCGGTCCGGTGCTGTCTTCGCCGGCTTGTGGTCCGTCCTGATGCTGGTCGGCGCTGCATCCGGGGGCG
AATCCGCTTTGCAGCCGTTGGCGCATCTGCGCGGTGGATCGACTTCGGCCGCATCCGCTGAGGCTGGTGTCGCTTTCGTC
CAGGCGAAATCGGTCGAGGACGTGGATGCGCATTTGGCCCAGGCGGCTTCGCGCGACCAATGGACCCTGATCGACTTCTA
CGCCGACTGGTGCGTCAGTTGTCATGTGATCGAGCGCAACGTATTCGGAGACCCCGCTGTCGCGTCCCGGCTGGCGCGCA
TGCAGGTGGTGCGGCCGGACGTCACGCGCAATGATGCAACCGACCAGGCTCTGCTCAAGCGCTGGGGCGTCATGGGACCG
CCCACACTCATTCTGGTTGGCCCGGACGGCAAGGAACGCCGGGATCTGCGCGTGGTGGGTGAGATCGATGCTCGCACCTT
CCTGGATCATCTGGACAAGGCGGGCTCCTGA

Upstream 100 bases:

>100_bases
GCTTAATCGAGCGAGCGCATCCTTCAAGCAGCTTTGCTTGGAGGATTCGGATTTGGCTTTTTATCGGCGCATAGTTGCGA
TCTTTCTACTGTGTTGTTGC

Downstream 100 bases:

>100_bases
TGATCAGCGTGGGGCCTTTCTCCGTCCAGGTCGTGGCTGTCTTCGCTGCCGTGCTGCTGGCCTGGGCAGTAGCTCGCATG
GTTGCCAAGCGACTGCCCGA

Product: putative thiol:disulfide interchange protein

Products: NA

Alternate protein names: Protein-disulfide reductase; Disulfide reductase [H]

Number of amino acids: Translated: 596; Mature: 596

Protein sequence:

>596_residues
MVGSAWANGLLPSWGSSERQFLDVAEVFKLDPAQQQGDSFLIAGHIADGYYVYRHAIKLVDARGHEISLTLPAGTAKHDE
FFGDTEIYKGDALNLRFPVTAAGPLTLHWQGCAEAGICYPPQTVNLALPEVAAGTSTAGNGSTHESPTAAPASQGSVAGA
TEIAEDQAAAQRLAALGPVWGTLLFFGFGLLLAFTPCSLPMIPIVSSMVVGSQAKPRRAFFLSLSYVVAMAGTYAVVGVA
AGMAGANLQATLQSPWLLGAFAALFLVLASSLFGLFELQMPSALVNRVESAGRDRSGGSIPGAAALGFLSALLVGPCMTA
PLAGALLYIGQTGSAVYGGMALFALGLGMGLPLLAIAVFGARVLPRPGAWMDRVRVAFGYVMVGMAVMMLTRFLPGTVGL
VLWGAWVLSVAIGLIAWGQAVAAKHRLAWTLRSGAVFAGLWSVLMLVGAASGGESALQPLAHLRGGSTSAASAEAGVAFV
QAKSVEDVDAHLAQAASRDQWTLIDFYADWCVSCHVIERNVFGDPAVASRLARMQVVRPDVTRNDATDQALLKRWGVMGP
PTLILVGPDGKERRDLRVVGEIDARTFLDHLDKAGS

Sequences:

>Translated_596_residues
MVGSAWANGLLPSWGSSERQFLDVAEVFKLDPAQQQGDSFLIAGHIADGYYVYRHAIKLVDARGHEISLTLPAGTAKHDE
FFGDTEIYKGDALNLRFPVTAAGPLTLHWQGCAEAGICYPPQTVNLALPEVAAGTSTAGNGSTHESPTAAPASQGSVAGA
TEIAEDQAAAQRLAALGPVWGTLLFFGFGLLLAFTPCSLPMIPIVSSMVVGSQAKPRRAFFLSLSYVVAMAGTYAVVGVA
AGMAGANLQATLQSPWLLGAFAALFLVLASSLFGLFELQMPSALVNRVESAGRDRSGGSIPGAAALGFLSALLVGPCMTA
PLAGALLYIGQTGSAVYGGMALFALGLGMGLPLLAIAVFGARVLPRPGAWMDRVRVAFGYVMVGMAVMMLTRFLPGTVGL
VLWGAWVLSVAIGLIAWGQAVAAKHRLAWTLRSGAVFAGLWSVLMLVGAASGGESALQPLAHLRGGSTSAASAEAGVAFV
QAKSVEDVDAHLAQAASRDQWTLIDFYADWCVSCHVIERNVFGDPAVASRLARMQVVRPDVTRNDATDQALLKRWGVMGP
PTLILVGPDGKERRDLRVVGEIDARTFLDHLDKAGS
>Mature_596_residues
MVGSAWANGLLPSWGSSERQFLDVAEVFKLDPAQQQGDSFLIAGHIADGYYVYRHAIKLVDARGHEISLTLPAGTAKHDE
FFGDTEIYKGDALNLRFPVTAAGPLTLHWQGCAEAGICYPPQTVNLALPEVAAGTSTAGNGSTHESPTAAPASQGSVAGA
TEIAEDQAAAQRLAALGPVWGTLLFFGFGLLLAFTPCSLPMIPIVSSMVVGSQAKPRRAFFLSLSYVVAMAGTYAVVGVA
AGMAGANLQATLQSPWLLGAFAALFLVLASSLFGLFELQMPSALVNRVESAGRDRSGGSIPGAAALGFLSALLVGPCMTA
PLAGALLYIGQTGSAVYGGMALFALGLGMGLPLLAIAVFGARVLPRPGAWMDRVRVAFGYVMVGMAVMMLTRFLPGTVGL
VLWGAWVLSVAIGLIAWGQAVAAKHRLAWTLRSGAVFAGLWSVLMLVGAASGGESALQPLAHLRGGSTSAASAEAGVAFV
QAKSVEDVDAHLAQAASRDQWTLIDFYADWCVSCHVIERNVFGDPAVASRLARMQVVRPDVTRNDATDQALLKRWGVMGP
PTLILVGPDGKERRDLRVVGEIDARTFLDHLDKAGS

Specific function: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a

COG id: COG4232

COG function: function code OC; Thiol:disulfide interchange protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1790578, Length=590, Percent_Identity=35.7627118644068, Blast_Score=348, Evalue=8e-97,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003834
- InterPro:   IPR022910
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF02683 DsbD; PF00085 Thioredoxin [H]

EC number: =1.8.1.8 [H]

Molecular weight: Translated: 62215; Mature: 62215

Theoretical pI: Translated: 6.74; Mature: 6.74

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVGSAWANGLLPSWGSSERQFLDVAEVFKLDPAQQQGDSFLIAGHIADGYYVYRHAIKLV
CCCCHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCHHHHHHHHHHH
DARGHEISLTLPAGTAKHDEFFGDTEIYKGDALNLRFPVTAAGPLTLHWQGCAEAGICYP
CCCCCEEEEEECCCCCCCHHCCCCCCEECCCEEEEEECEEECCCEEEEECCCCCCCCCCC
PQTVNLALPEVAAGTSTAGNGSTHESPTAAPASQGSVAGATEIAEDQAAAQRLAALGPVW
CCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
GTLLFFGFGLLLAFTPCSLPMIPIVSSMVVGSQAKPRRAFFLSLSYVVAMAGTYAVVGVA
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
AGMAGANLQATLQSPWLLGAFAALFLVLASSLFGLFELQMPSALVNRVESAGRDRSGGSI
HCCCCCCCEEHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCC
PGAAALGFLSALLVGPCMTAPLAGALLYIGQTGSAVYGGMALFALGLGMGLPLLAIAVFG
CHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCCHHHHHHHHHHHHHCCCHHHHHHHHHH
ARVLPRPGAWMDRVRVAFGYVMVGMAVMMLTRFLPGTVGLVLWGAWVLSVAIGLIAWGQA
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
VAAKHRLAWTLRSGAVFAGLWSVLMLVGAASGGESALQPLAHLRGGSTSAASAEAGVAFV
HHHHHHHEEEECCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCEEEE
QAKSVEDVDAHLAQAASRDQWTLIDFYADWCVSCHVIERNVFGDPAVASRLARMQVVRPD
EECCCHHHHHHHHHHCCCCCEEEHHHHHHHHHEEEEEECCCCCCHHHHHHHHHHHHCCCC
VTRNDATDQALLKRWGVMGPPTLILVGPDGKERRDLRVVGEIDARTFLDHLDKAGS
CCCCCCHHHHHHHHCCCCCCCEEEEECCCCCCCCCEEEEECCHHHHHHHHHHCCCC
>Mature Secondary Structure
MVGSAWANGLLPSWGSSERQFLDVAEVFKLDPAQQQGDSFLIAGHIADGYYVYRHAIKLV
CCCCHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCHHHHHHHHHHH
DARGHEISLTLPAGTAKHDEFFGDTEIYKGDALNLRFPVTAAGPLTLHWQGCAEAGICYP
CCCCCEEEEEECCCCCCCHHCCCCCCEECCCEEEEEECEEECCCEEEEECCCCCCCCCCC
PQTVNLALPEVAAGTSTAGNGSTHESPTAAPASQGSVAGATEIAEDQAAAQRLAALGPVW
CCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
GTLLFFGFGLLLAFTPCSLPMIPIVSSMVVGSQAKPRRAFFLSLSYVVAMAGTYAVVGVA
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
AGMAGANLQATLQSPWLLGAFAALFLVLASSLFGLFELQMPSALVNRVESAGRDRSGGSI
HCCCCCCCEEHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCC
PGAAALGFLSALLVGPCMTAPLAGALLYIGQTGSAVYGGMALFALGLGMGLPLLAIAVFG
CHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCCHHHHHHHHHHHHHCCCHHHHHHHHHH
ARVLPRPGAWMDRVRVAFGYVMVGMAVMMLTRFLPGTVGLVLWGAWVLSVAIGLIAWGQA
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
VAAKHRLAWTLRSGAVFAGLWSVLMLVGAASGGESALQPLAHLRGGSTSAASAEAGVAFV
HHHHHHHEEEECCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCEEEE
QAKSVEDVDAHLAQAASRDQWTLIDFYADWCVSCHVIERNVFGDPAVASRLARMQVVRPD
EECCCHHHHHHHHHHCCCCCEEEHHHHHHHHHEEEEEECCCCCCHHHHHHHHHHHHCCCC
VTRNDATDQALLKRWGVMGPPTLILVGPDGKERRDLRVVGEIDARTFLDHLDKAGS
CCCCCCHHHHHHHHCCCCCCCEEEEECCCCCCCCCEEEEECCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA