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The map label for this gene is yccK [H]

Identifier: 78047731

GI number: 78047731

Start: 2500179

End: 2501018

Strand: Reverse

Name: yccK [H]

Synonym: XCV2175

Alternate gene names: 78047731

Gene position: 2501018-2500179 (Counterclockwise)

Preceding gene: 78047732

Following gene: 78047729

Centisome position: 48.3

GC content: 63.57

Gene sequence:

>840_bases
ATGAAATGCGTCGCTTCGATAATGGATTGGAGAGGGCTGCCGCTCGATAATGTGATCTCCCCGTGTCCTGCGATCCTCTT
CCCTACGGCAGCGAGGACCTCTCATGCACTACGCCCAGTTTGGTCGCACCGGTCTTTTCGTGTCGAAGTTCTGCCTCGGC
GGCATGACCTTCGGTGGTGCCACGACGCCTGCGGGTGCAGCCATTGGGCGCCTGTCGCAGCAGGAGACGAACGCCATCGT
CGACCAGGCCCTCGATGCCGGCATCAACTTCATCGATACAGCGGACGTCTACGGCGGCGGCGATTGACGCGGTGCGCCTC
CCTTCAGGCCTACTACTCCATCGCGGGGCGGGACATCGAACATGAGCTGGTGCCTGCGGTCATGGATGCACAGATCGGCC
TGCTATGTTGGAGTCCGCTGGCCGGCGGACTGCTCTCCGGCAAGTTCGATCGCCATGGTCACACAGACAACACCGCGCGC
CGCGCGTCGATCGCCTTTCCGCCGGTTGACGAAACACGGGTGCACGACATCATCGACACCTTGAAGACCGTGGCCGCGCG
GCATGACGCGACCGCTGCCCAGATCGCGCTCGCATGGCTGCTCTCTCGTCCGGCGGTCACCAGCGTCATCGTCGGCCTCA
AACGCCCCGAGCAACTGACCGAGAACCTCGGAGCGCTGGAACTGACGCTTTCGAGCGAGGACCTGGCCGAACTCGACCAA
GTCAGCCGACCCGCTGCCGCGTACCCGGGTTGGATCCAACGCTATAACGCCAGAAGCCGGGTTCCAGCCGGTCATGCATT
CGAGGGACCGAGTTGGAGCCTTGGCGAGCGTCCGCTCTAG

Upstream 100 bases:

>100_bases
GCCGTGTCCGGCGCCCCTGCGCATCCCTGCGTGGTCAGCAGGCTGCCGAAGCGGAGCAGCGAGAAGGCGTCGAACAGGGT
CCATGCCTGGCCGGTGGATG

Downstream 100 bases:

>100_bases
CCCGACCTGCCTGCGTCTGGAGCGGACGTGGTCCGGGCCTAGACGGCGAGAACGCCACGGAGCAGTGAGAAGGATGGCAA
GTCCGGGATGCAGCTCCAAC

Product: putative oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 279; Mature: 279

Protein sequence:

>279_residues
MKCVASIMDWRGLPLDNVISPCPAILFPTAARTSHALRPVWSHRSFRVEVLPRRHDLRWCHDACGCSHWAPVAAGDERHR
RPGPRCRHQLHRYSGRLRRRRLTRCASLQAYYSIAGRDIEHELVPAVMDAQIGLLCWSPLAGGLLSGKFDRHGHTDNTAR
RASIAFPPVDETRVHDIIDTLKTVAARHDATAAQIALAWLLSRPAVTSVIVGLKRPEQLTENLGALELTLSSEDLAELDQ
VSRPAAAYPGWIQRYNARSRVPAGHAFEGPSWSLGERPL

Sequences:

>Translated_279_residues
MKCVASIMDWRGLPLDNVISPCPAILFPTAARTSHALRPVWSHRSFRVEVLPRRHDLRWCHDACGCSHWAPVAAGDERHR
RPGPRCRHQLHRYSGRLRRRRLTRCASLQAYYSIAGRDIEHELVPAVMDAQIGLLCWSPLAGGLLSGKFDRHGHTDNTAR
RASIAFPPVDETRVHDIIDTLKTVAARHDATAAQIALAWLLSRPAVTSVIVGLKRPEQLTENLGALELTLSSEDLAELDQ
VSRPAAAYPGWIQRYNARSRVPAGHAFEGPSWSLGERPL
>Mature_279_residues
MKCVASIMDWRGLPLDNVISPCPAILFPTAARTSHALRPVWSHRSFRVEVLPRRHDLRWCHDACGCSHWAPVAAGDERHR
RPGPRCRHQLHRYSGRLRRRRLTRCASLQAYYSIAGRDIEHELVPAVMDAQIGLLCWSPLAGGLLSGKFDRHGHTDNTAR
RASIAFPPVDETRVHDIIDTLKTVAARHDATAAQIALAWLLSRPAVTSVIVGLKRPEQLTENLGALELTLSSEDLAELDQ
VSRPAAAYPGWIQRYNARSRVPAGHAFEGPSWSLGERPL

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436962, Length=146, Percent_Identity=32.1917808219178, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI27436966, Length=146, Percent_Identity=32.1917808219178, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI27436964, Length=146, Percent_Identity=32.1917808219178, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI87081735, Length=144, Percent_Identity=34.0277777777778, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1788070, Length=127, Percent_Identity=35.4330708661417, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1789375, Length=140, Percent_Identity=32.8571428571429, Blast_Score=69, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6325169, Length=140, Percent_Identity=30, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 31117; Mature: 31117

Theoretical pI: Translated: 9.65; Mature: 9.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKCVASIMDWRGLPLDNVISPCPAILFPTAARTSHALRPVWSHRSFRVEVLPRRHDLRWC
CHHHHHHHHCCCCCHHHHHCCCCHHHCCCHHHHHHHHHHHHCCCCEEEEECCCCCCHHHH
HDACGCSHWAPVAAGDERHRRPGPRCRHQLHRYSGRLRRRRLTRCASLQAYYSIAGRDIE
HHHCCCCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
HELVPAVMDAQIGLLCWSPLAGGLLSGKFDRHGHTDNTARRASIAFPPVDETRVHDIIDT
HHHHHHHHHHHHHHEECCHHHCHHHCCCCCCCCCCCCCHHHCEECCCCCCHHHHHHHHHH
LKTVAARHDATAAQIALAWLLSRPAVTSVIVGLKRPEQLTENLGALELTLSSEDLAELDQ
HHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHCCCEEEEEECCHHHHHHHH
VSRPAAAYPGWIQRYNARSRVPAGHAFEGPSWSLGERPL
HCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKCVASIMDWRGLPLDNVISPCPAILFPTAARTSHALRPVWSHRSFRVEVLPRRHDLRWC
CHHHHHHHHCCCCCHHHHHCCCCHHHCCCHHHHHHHHHHHHCCCCEEEEECCCCCCHHHH
HDACGCSHWAPVAAGDERHRRPGPRCRHQLHRYSGRLRRRRLTRCASLQAYYSIAGRDIE
HHHCCCCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
HELVPAVMDAQIGLLCWSPLAGGLLSGKFDRHGHTDNTARRASIAFPPVDETRVHDIIDT
HHHHHHHHHHHHHHEECCHHHCHHHCCCCCCCCCCCCCHHHCEECCCCCCHHHHHHHHHH
LKTVAARHDATAAQIALAWLLSRPAVTSVIVGLKRPEQLTENLGALELTLSSEDLAELDQ
HHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHCCCEEEEEECCHHHHHHHH
VSRPAAAYPGWIQRYNARSRVPAGHAFEGPSWSLGERPL
HCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9274031; 9384377; 9106203 [H]