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The map label for this gene is fadB [H]

Identifier: 78047620

GI number: 78047620

Start: 2353243

End: 2355615

Strand: Reverse

Name: fadB [H]

Synonym: XCV2064

Alternate gene names: 78047620

Gene position: 2355615-2353243 (Counterclockwise)

Preceding gene: 78047621

Following gene: 78047619

Centisome position: 45.49

GC content: 64.81

Gene sequence:

>2373_bases
ATGTCCAACCCGTTGCTAGTCCGTCGTGCCGCCGTGCTCGGTGCCGGCGTCATGGGTGCGCAGATCGCCGCGCACCTCAC
CAATGCCGGTGTCGACACCGTGTTGTTCGACCTGCCCGCCAAGGAAGGCCCGGCAGACGGCATCGTACTCAAGGCGATCA
CCAATCTCGGCAAGCTGAGCCCCGCCCCGCTCGCCAGCAAGGCGCTGGCCGAGGCGATCACGCCGGCCAATTACGAGAGC
GGCCTGGAACAGCTGCGCGACTGCGATCTGATCATCGAAGCGATCGCCGAGCGCATGGACTGGAAGCAGGACCTGTACAA
GAAGATCGCCCCGTTCGTGGCCGATCATGCCGTGCTGGCCTCCAACACCTCCGGCCTGGGCATCAACAAGCTCTCCGACG
TGCTGCCCGAGCAGTTGCGTCACCGCTTTTGCGGCGTGCATTTCTTCAATCCGCCGCGCTACATGCACCTGGCCGAATTG
ATCCCGGCCAAGGGCACCGACAAGGCGGTACTGGAAGGCCTGGAAGCCTTCCTGGTGACCACGCTCGGCAAGGGCGTGGT
GTATGCGAAGGACACCCCGAACTTCATCGGCAACCGCATCGGCGTGTTCTCGATCCTGTCCACCATCCACCACACGCAGG
AATTCGGCCTGGGCTTCGACGAAGTCGATGCGCTGACCGGCCCGCTGGTGGGTCGCCCGAAGTCGGCCACCTATCGCACC
TCCGATGTGGTCGGCCTGGACACCATGGCGCACGTCATCAAGACCATGGGCGACACCCTGCCCGACGACCCGTGGCACCA
GTACTTCAAATCACCCAAGTGGCTGGAGGCGCTGATCGGCAAGGGCGCGCTGGGCCAGAAGGTCGGTGCCGGCATCTTCC
GCAAGGTCGGCAAGGACATCGTGGTGGTCGACCTGGAGAAGCAGGACTATCGCCCGGCCGATCGTAGCGCCGCGCCGGAA
GTGGTCGAGATCCTCAAGATCAAGAACCCGACCGAAAAGTTCGCCAAGCTGCGCGAAAGCCAGCACCCGCAGGCGCAGTT
CCTGTGGGCCAGCTTCCGCGACCTGTTCCACTACAGCGCCTACCACCTGGCCGATATCGCCGAGACCGCACGCGACGTGG
ATCTGGCGATCCGCTGGGGCTACGGCTGGTCGCTGGGTCCGTTCGAGACCTGGCAGGCCGCTGGCTGGAAGCAGGTGGCG
CAGTGGATTGCCGAAGACATCTCCAACGGCAAGAGCATGAGCAGCGCGCCACTACCGAACTGGGTGTTCGACGGTCGCGA
TGGCGTGCATGGCGCCGAAGGCTCGTACAGCCCGGCGCGCGACGCCAAGCTGCCACGCTCGTCGCTGCCGGTGTACAAGC
GCCAGCGCTTCCCCGATCCGTTGCTGGGCGAGCAGTTCTCGCCGGGCGAAACCGTGTTCGAAAATGACGGCGTGCGCATG
TGGCACGACGGCGACGACATCGCCGTGGTCAGTTTCAAGACCAAGATGAACACCGTCTCCGACCACGTGCTCAATGGCCT
GCAGGAAGTGGTTGGCCGCGCCGAGAAAGACTTCGCCGGTCTGGTGATCTGGCAGCAGAAGGAGCCCTTCTCCGCCGGTG
CCGATCTGGCCGGCGCGCTTGGCCTGCTGCAGGCCGGCAAGGTCGATGCGTTCGAAGCATTGGTCGCCAATTTCCAGGCC
ACCAGCCAGCGCATCAAGTACGCGCAGGTGCCGGTGATCTCGGCCGTGCGTGGCCTGGCGCTGGGCGGCGGCTGCGAATT
CCAGATGCATAGCGCCAAGACCGTGGCTTCGCTGGAGAGCTACATCGGCCTGGTCGAAGCCGGCGTCGGCCTGCTGCCGG
CCGGTGGTGGCCTGAAGGAAATCGCGGTGCGTGCGTCGATCGCCGCAGGTCCGGGCGGCGACGTGTTCGCCGAGCTGAAG
AAGACCTTCGAGACCGTGGCAATGGCCAAGGTCTCCAACTCGGCCGTCAATGCCAAGGAACTGGGCCTGCTGCGTGCCAC
CGACAAGGTGGTGTTCAACAGCTACGAGAGCCTGCACATCGCCAAGGCCGAAGCACGCGCACTGGCCGAGGGCGGCTACC
GCGCCCCGCTGCCGGCACGCCGCATCCAGGTCGCCGGCGACGTCGGCATCGCCACCTTCAAGATGCTGCTGGTCAACATG
CTGGAAGGTCGCTTCATCAGCGAATACGACTACGAAATCGCCAGCCGCATCGCCACGGTGGTCTGCGGTGGCGAAGTGGA
TCGCGGCGCGCTGGTCGATGAAGAATGGCTGCTCAAGCTGGAGCGCAAGCACTTCGTCGAACTGGCCCAGCAGGAAAAGA
CCCAGGCGCGGATTGGGCACATGCTCAAGACGGGTAAGCCACTCAGGAACTGA

Upstream 100 bases:

>100_bases
CGACCATCGTGCGCGCGCGGCGCGCGAACTCATCCGTTTCGCGGAACCCGGGTTCCGCGCTCATTCCACACCGTAAACGT
TCCACAAGAGGCCTATCGCT

Downstream 100 bases:

>100_bases
GAATCGGGATTGGGGATTGGGGATTCGCAACAGCGGGTCCCCGCCCTCCAACTTTCTCGCTTCCACCAAATTCATCCGCC
GGGCAGGAACATTCGGGCAC

Product: 3-hydroxyacyl-CoA dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 790; Mature: 789

Protein sequence:

>790_residues
MSNPLLVRRAAVLGAGVMGAQIAAHLTNAGVDTVLFDLPAKEGPADGIVLKAITNLGKLSPAPLASKALAEAITPANYES
GLEQLRDCDLIIEAIAERMDWKQDLYKKIAPFVADHAVLASNTSGLGINKLSDVLPEQLRHRFCGVHFFNPPRYMHLAEL
IPAKGTDKAVLEGLEAFLVTTLGKGVVYAKDTPNFIGNRIGVFSILSTIHHTQEFGLGFDEVDALTGPLVGRPKSATYRT
SDVVGLDTMAHVIKTMGDTLPDDPWHQYFKSPKWLEALIGKGALGQKVGAGIFRKVGKDIVVVDLEKQDYRPADRSAAPE
VVEILKIKNPTEKFAKLRESQHPQAQFLWASFRDLFHYSAYHLADIAETARDVDLAIRWGYGWSLGPFETWQAAGWKQVA
QWIAEDISNGKSMSSAPLPNWVFDGRDGVHGAEGSYSPARDAKLPRSSLPVYKRQRFPDPLLGEQFSPGETVFENDGVRM
WHDGDDIAVVSFKTKMNTVSDHVLNGLQEVVGRAEKDFAGLVIWQQKEPFSAGADLAGALGLLQAGKVDAFEALVANFQA
TSQRIKYAQVPVISAVRGLALGGGCEFQMHSAKTVASLESYIGLVEAGVGLLPAGGGLKEIAVRASIAAGPGGDVFAELK
KTFETVAMAKVSNSAVNAKELGLLRATDKVVFNSYESLHIAKAEARALAEGGYRAPLPARRIQVAGDVGIATFKMLLVNM
LEGRFISEYDYEIASRIATVVCGGEVDRGALVDEEWLLKLERKHFVELAQQEKTQARIGHMLKTGKPLRN

Sequences:

>Translated_790_residues
MSNPLLVRRAAVLGAGVMGAQIAAHLTNAGVDTVLFDLPAKEGPADGIVLKAITNLGKLSPAPLASKALAEAITPANYES
GLEQLRDCDLIIEAIAERMDWKQDLYKKIAPFVADHAVLASNTSGLGINKLSDVLPEQLRHRFCGVHFFNPPRYMHLAEL
IPAKGTDKAVLEGLEAFLVTTLGKGVVYAKDTPNFIGNRIGVFSILSTIHHTQEFGLGFDEVDALTGPLVGRPKSATYRT
SDVVGLDTMAHVIKTMGDTLPDDPWHQYFKSPKWLEALIGKGALGQKVGAGIFRKVGKDIVVVDLEKQDYRPADRSAAPE
VVEILKIKNPTEKFAKLRESQHPQAQFLWASFRDLFHYSAYHLADIAETARDVDLAIRWGYGWSLGPFETWQAAGWKQVA
QWIAEDISNGKSMSSAPLPNWVFDGRDGVHGAEGSYSPARDAKLPRSSLPVYKRQRFPDPLLGEQFSPGETVFENDGVRM
WHDGDDIAVVSFKTKMNTVSDHVLNGLQEVVGRAEKDFAGLVIWQQKEPFSAGADLAGALGLLQAGKVDAFEALVANFQA
TSQRIKYAQVPVISAVRGLALGGGCEFQMHSAKTVASLESYIGLVEAGVGLLPAGGGLKEIAVRASIAAGPGGDVFAELK
KTFETVAMAKVSNSAVNAKELGLLRATDKVVFNSYESLHIAKAEARALAEGGYRAPLPARRIQVAGDVGIATFKMLLVNM
LEGRFISEYDYEIASRIATVVCGGEVDRGALVDEEWLLKLERKHFVELAQQEKTQARIGHMLKTGKPLRN
>Mature_789_residues
SNPLLVRRAAVLGAGVMGAQIAAHLTNAGVDTVLFDLPAKEGPADGIVLKAITNLGKLSPAPLASKALAEAITPANYESG
LEQLRDCDLIIEAIAERMDWKQDLYKKIAPFVADHAVLASNTSGLGINKLSDVLPEQLRHRFCGVHFFNPPRYMHLAELI
PAKGTDKAVLEGLEAFLVTTLGKGVVYAKDTPNFIGNRIGVFSILSTIHHTQEFGLGFDEVDALTGPLVGRPKSATYRTS
DVVGLDTMAHVIKTMGDTLPDDPWHQYFKSPKWLEALIGKGALGQKVGAGIFRKVGKDIVVVDLEKQDYRPADRSAAPEV
VEILKIKNPTEKFAKLRESQHPQAQFLWASFRDLFHYSAYHLADIAETARDVDLAIRWGYGWSLGPFETWQAAGWKQVAQ
WIAEDISNGKSMSSAPLPNWVFDGRDGVHGAEGSYSPARDAKLPRSSLPVYKRQRFPDPLLGEQFSPGETVFENDGVRMW
HDGDDIAVVSFKTKMNTVSDHVLNGLQEVVGRAEKDFAGLVIWQQKEPFSAGADLAGALGLLQAGKVDAFEALVANFQAT
SQRIKYAQVPVISAVRGLALGGGCEFQMHSAKTVASLESYIGLVEAGVGLLPAGGGLKEIAVRASIAAGPGGDVFAELKK
TFETVAMAKVSNSAVNAKELGLLRATDKVVFNSYESLHIAKAEARALAEGGYRAPLPARRIQVAGDVGIATFKMLLVNML
EGRFISEYDYEIASRIATVVCGGEVDRGALVDEEWLLKLERKHFVELAQQEKTQARIGHMLKTGKPLRN

Specific function: Involved in the degradation of long-chain fatty acids [H]

COG id: COG1250

COG function: function code I; 3-hydroxyacyl-CoA dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI296179429, Length=296, Percent_Identity=31.0810810810811, Blast_Score=121, Evalue=2e-27,
Organism=Homo sapiens, GI296179427, Length=313, Percent_Identity=30.9904153354633, Blast_Score=120, Evalue=6e-27,
Organism=Homo sapiens, GI20127408, Length=304, Percent_Identity=29.2763157894737, Blast_Score=96, Evalue=1e-19,
Organism=Homo sapiens, GI261878539, Length=387, Percent_Identity=23.5142118863049, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI68989263, Length=395, Percent_Identity=23.2911392405063, Blast_Score=69, Evalue=2e-11,
Organism=Escherichia coli, GI1790281, Length=315, Percent_Identity=26.031746031746, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1787661, Length=307, Percent_Identity=28.6644951140065, Blast_Score=88, Evalue=3e-18,
Organism=Escherichia coli, GI1788682, Length=215, Percent_Identity=27.906976744186, Blast_Score=68, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17549919, Length=300, Percent_Identity=28.3333333333333, Blast_Score=103, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI17553560, Length=291, Percent_Identity=27.4914089347079, Blast_Score=101, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17563036, Length=298, Percent_Identity=29.1946308724832, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17558304, Length=329, Percent_Identity=29.483282674772, Blast_Score=92, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17508953, Length=293, Percent_Identity=31.740614334471, Blast_Score=91, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17508951, Length=293, Percent_Identity=31.740614334471, Blast_Score=91, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI25144276, Length=293, Percent_Identity=31.740614334471, Blast_Score=91, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI71985923, Length=264, Percent_Identity=26.8939393939394, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI71985930, Length=416, Percent_Identity=21.1538461538462, Blast_Score=78, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24583077, Length=399, Percent_Identity=27.5689223057644, Blast_Score=84, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24583079, Length=399, Percent_Identity=27.5689223057644, Blast_Score=84, Evalue=5e-16,
Organism=Drosophila melanogaster, GI19921000, Length=399, Percent_Identity=27.5689223057644, Blast_Score=84, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006176
- InterPro:   IPR006108
- InterPro:   IPR008927
- InterPro:   IPR001753
- InterPro:   IPR013328
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00725 3HCDH; PF02737 3HCDH_N; PF00378 ECH [H]

EC number: =1.1.1.35 [H]

Molecular weight: Translated: 85678; Mature: 85547

Theoretical pI: Translated: 6.84; Mature: 6.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNPLLVRRAAVLGAGVMGAQIAAHLTNAGVDTVLFDLPAKEGPADGIVLKAITNLGKLS
CCCCHHHHHHHHHHCCHHHHHHHHHHHCCCHHHEEEECCCCCCCCCCCHHHHHHHHCCCC
PAPLASKALAEAITPANYESGLEQLRDCDLIIEAIAERMDWKQDLYKKIAPFVADHAVLA
CCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHEE
SNTSGLGINKLSDVLPEQLRHRFCGVHFFNPPRYMHLAELIPAKGTDKAVLEGLEAFLVT
CCCCCCCHHHHHHHHHHHHHHHHCCCEECCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHH
TLGKGVVYAKDTPNFIGNRIGVFSILSTIHHTQEFGLGFDEVDALTGPLVGRPKSATYRT
HHCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCCC
SDVVGLDTMAHVIKTMGDTLPDDPWHQYFKSPKWLEALIGKGALGQKVGAGIFRKVGKDI
CCCCCHHHHHHHHHHHCCCCCCCHHHHHHCCCHHHHHHHCCCCCCHHHHHHHHHHCCCCE
VVVDLEKQDYRPADRSAAPEVVEILKIKNPTEKFAKLRESQHPQAQFLWASFRDLFHYSA
EEEECCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
YHLADIAETARDVDLAIRWGYGWSLGPFETWQAAGWKQVAQWIAEDISNGKSMSSAPLPN
HHHHHHHHHHHCCEEEEEECCCCCCCCCHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCC
WVFDGRDGVHGAEGSYSPARDAKLPRSSLPVYKRQRFPDPLLGEQFSPGETVFENDGVRM
CEECCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCEECCCCEEE
WHDGDDIAVVSFKTKMNTVSDHVLNGLQEVVGRAEKDFAGLVIWQQKEPFSAGADLAGAL
EECCCCEEEEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCHHHHHH
GLLQAGKVDAFEALVANFQATSQRIKYAQVPVISAVRGLALGGGCEFQMHSAKTVASLES
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCEEECCHHHHHHHHH
YIGLVEAGVGLLPAGGGLKEIAVRASIAAGPGGDVFAELKKTFETVAMAKVSNSAVNAKE
HHHHHHHCCCEEECCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHH
LGLLRATDKVVFNSYESLHIAKAEARALAEGGYRAPLPARRIQVAGDVGIATFKMLLVNM
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCHHHEEECCCCHHHHHHHHHHHH
LEGRFISEYDYEIASRIATVVCGGEVDRGALVDEEWLLKLERKHFVELAQQEKTQARIGH
HCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
MLKTGKPLRN
HHHCCCCCCC
>Mature Secondary Structure 
SNPLLVRRAAVLGAGVMGAQIAAHLTNAGVDTVLFDLPAKEGPADGIVLKAITNLGKLS
CCCHHHHHHHHHHCCHHHHHHHHHHHCCCHHHEEEECCCCCCCCCCCHHHHHHHHCCCC
PAPLASKALAEAITPANYESGLEQLRDCDLIIEAIAERMDWKQDLYKKIAPFVADHAVLA
CCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHEE
SNTSGLGINKLSDVLPEQLRHRFCGVHFFNPPRYMHLAELIPAKGTDKAVLEGLEAFLVT
CCCCCCCHHHHHHHHHHHHHHHHCCCEECCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHH
TLGKGVVYAKDTPNFIGNRIGVFSILSTIHHTQEFGLGFDEVDALTGPLVGRPKSATYRT
HHCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCCC
SDVVGLDTMAHVIKTMGDTLPDDPWHQYFKSPKWLEALIGKGALGQKVGAGIFRKVGKDI
CCCCCHHHHHHHHHHHCCCCCCCHHHHHHCCCHHHHHHHCCCCCCHHHHHHHHHHCCCCE
VVVDLEKQDYRPADRSAAPEVVEILKIKNPTEKFAKLRESQHPQAQFLWASFRDLFHYSA
EEEECCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
YHLADIAETARDVDLAIRWGYGWSLGPFETWQAAGWKQVAQWIAEDISNGKSMSSAPLPN
HHHHHHHHHHHCCEEEEEECCCCCCCCCHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCC
WVFDGRDGVHGAEGSYSPARDAKLPRSSLPVYKRQRFPDPLLGEQFSPGETVFENDGVRM
CEECCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCEECCCCEEE
WHDGDDIAVVSFKTKMNTVSDHVLNGLQEVVGRAEKDFAGLVIWQQKEPFSAGADLAGAL
EECCCCEEEEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCHHHHHH
GLLQAGKVDAFEALVANFQATSQRIKYAQVPVISAVRGLALGGGCEFQMHSAKTVASLES
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCEEECCHHHHHHHHH
YIGLVEAGVGLLPAGGGLKEIAVRASIAAGPGGDVFAELKKTFETVAMAKVSNSAVNAKE
HHHHHHHCCCEEECCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHH
LGLLRATDKVVFNSYESLHIAKAEARALAEGGYRAPLPARRIQVAGDVGIATFKMLLVNM
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCHHHEEECCCCHHHHHHHHHHHH
LEGRFISEYDYEIASRIATVVCGGEVDRGALVDEEWLLKLERKHFVELAQQEKTQARIGH
HCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
MLKTGKPLRN
HHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]