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The map label for this gene is flhA [H]

Identifier: 78047536

GI number: 78047536

Start: 2255442

End: 2257535

Strand: Reverse

Name: flhA [H]

Synonym: XCV1980

Alternate gene names: 78047536

Gene position: 2257535-2255442 (Counterclockwise)

Preceding gene: 78047537

Following gene: 78047535

Centisome position: 43.59

GC content: 67.86

Gene sequence:

>2094_bases
ATGAGCGCCCGCCCCGCCCCGATGAACGCCCGCCGCGTCATGGAGTTGCTGCGCAACGGCCTGGGCGCCCCGCTGGCCCT
GATGGCCATGCTGGCCATGCTGATGGTGCCGCTGGCCGCGCCGGTGCTGGATGCGCTGTTCACCTTCAACATCGCCATCT
CGCTGATGGTGCTGCTGGCGGTGGTGTACGTGCAGCGCCCGCTGGAATTCACCATTTTCCCGATCGTGCTGTTGATGACC
ACGATGCTGCGGCTGGCGCTGAACGTCGCCTCCAGCCGCGTGATCCTGATCAACGGCCAGGACGGTCACGCCGCCGCCGG
CAAGGTCATCGAGGCCTTCGGCCAGTTCGTGATCGGCGGCAATTACGCCGTGGGTATCGTGGTGTTCGCGATCCTGACCA
TCATCAACTTCGTGGTCATCACCAAGGGTGCCGGACGCGTGTCGGAAGTGACCGCGCGCTTCATCCTGGACGCCATGCCC
GGCAAGCAGATGGCCATCGACGCCGACCTCAACGCCGGTTTGCTGACGCGCGAGGAGGCCAAGGCCCGCCGCGAGGAAGT
GCGCGAGGAAGCCGACTTCTACGGTGCGATGGACGGTGCCAACAAGTTCATCCGCGGCGACGCCATCGCCGCCATCCTGA
TCCTGTTCATCAACCTCATCGGCGGCATGGCGGTGGGCATGCTCCAGCACGGCATGAGCTTCATGGATGCCGCCTCCACC
TACACGTTGCTGTCCATCGGCGACGGCCTGGTGGCGCAGCTGCCGGCCCTGCTGGTTTCGTCTTCGGTCGCCTTGCTGGT
GACCCGCGCCTCGCGTGCGCAGGACATGCGCGGGGCCATGGTCAGCCAGGTGTTCGGCCAGCACCGCGCCTTGGCGGTGG
CTGCGGCCATCCTCGGCCTGGTCGGCCTGGTGCCCGGCATGCCGAACGTCGCGTTTTTGACGCTGGGCCTGGTCCTGGGC
GTGATCGCCTGGAAGCTGTACAAGCGCAGCCTGGCAAAGCCGGCGGCCGGCGATCCGGCGGCCGATCCGCAGGCGGCGGC
CGCGGCGACCGCCGCCCAGGCCAGCGCCGAGCTGAGCTGGGACGAACTGCGCCCGATCGACCCGCTGGGCCTGGAAGTGG
GCTACCGGCTGATCCCGCTAGTGGACAAGAACCAGGGCGGCGAACTGATGGCGCGCATCAAGGGCGTGCGCCGCAAGCTC
ACCCAGGACATCGGGTTCCTGGTGCCGCCGGTGCATATCCGCGACAACCTGGAACTGTCGGCCAATGCCTACCGGCTACT
GGTGCATGGCGTGCCGGTGGCCACCGCAGAAATCTATTCCGACCGCGAACTGGCACTGGACCCGGGCGGTGCGCTCGGCC
AGCTCGACGGCATCCCCGGCAAGGACCCGGCATTCGGCCTGGACGCCACCTGGATCCAGCCGCACCAGCGCGCCTATGCC
GAATCGATGGGCTACACCGTGGTCGACCCGGCGACCGTGGTCGCCACCCACCTGTCGCACCTGATCCGCGAGCATGCGCC
CGAACTGCTCGGCCATGAAGAAGTGCAGCAATTGCTGGCCACGCTGGCCAAGACCGCGCCGAAGATGGTCGAAGACCTCA
CCCCGAAGGCACTGCCGCTGTCGGTGGTGGTGCGCGTGCTGCAGAACCTGCTGATCGAGAAGATTCCGGTGCGGCAACTG
CGCAAGATTGTCGAAGCGCTGGTCGAACACGCCCCGCATAGCCAGGACCCGGCCACCCTCACCGCCGCCGTGCGTACCTC
GCTGGGCCGCTTCATCGTGCAGGAAATCGCCGGCATGTCGGCCGAGCTGCCGGTGTTCACCCTGGCCCCGCAGCTGGAGC
GCGTCCTGCAGGAATCCACCCACGGCAACGGCGTGGCGCTGGAGCCCGGGCTGGCCGAACGCCTGCACCAGAGCCTGGCC
GATTGCGTGGGCAAGCAGGAAGCCCGCAACGAACCGGCGGTGGTGCTGGTGCCCGGCCAGGTGCGCGCCGCACTGGCCCG
TCTGGTGCGCCACAGCGTGCCCAGCCTGTCGGTGCTGGCCTACAGCGAAGTGCCAGAAGACAAGCGCTTGAAGCTGGTCG
GCACGATCAGCTGA

Upstream 100 bases:

>100_bases
AGGTGCTCTCCTACGTCTACCAGCTGCGTGGCTGGAACGGCGGCCCGATGCCGGAACTGCCCTCGCTTGAGGTGGATGAG
TTCGGCAAGGGAGCCAGCGC

Downstream 100 bases:

>100_bases
GACCGTCCAGCAACAACGCACCCATCGCCCGCCGGGCTTGCCGGGACGGCCCGTCGCGCCCGGGTGCGCTCCTACGACAT
CCAAGGCGATCGGGAAATAT

Product: flagellar biosynthesis protein FlhA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 697; Mature: 696

Protein sequence:

>697_residues
MSARPAPMNARRVMELLRNGLGAPLALMAMLAMLMVPLAAPVLDALFTFNIAISLMVLLAVVYVQRPLEFTIFPIVLLMT
TMLRLALNVASSRVILINGQDGHAAAGKVIEAFGQFVIGGNYAVGIVVFAILTIINFVVITKGAGRVSEVTARFILDAMP
GKQMAIDADLNAGLLTREEAKARREEVREEADFYGAMDGANKFIRGDAIAAILILFINLIGGMAVGMLQHGMSFMDAAST
YTLLSIGDGLVAQLPALLVSSSVALLVTRASRAQDMRGAMVSQVFGQHRALAVAAAILGLVGLVPGMPNVAFLTLGLVLG
VIAWKLYKRSLAKPAAGDPAADPQAAAAATAAQASAELSWDELRPIDPLGLEVGYRLIPLVDKNQGGELMARIKGVRRKL
TQDIGFLVPPVHIRDNLELSANAYRLLVHGVPVATAEIYSDRELALDPGGALGQLDGIPGKDPAFGLDATWIQPHQRAYA
ESMGYTVVDPATVVATHLSHLIREHAPELLGHEEVQQLLATLAKTAPKMVEDLTPKALPLSVVVRVLQNLLIEKIPVRQL
RKIVEALVEHAPHSQDPATLTAAVRTSLGRFIVQEIAGMSAELPVFTLAPQLERVLQESTHGNGVALEPGLAERLHQSLA
DCVGKQEARNEPAVVLVPGQVRAALARLVRHSVPSLSVLAYSEVPEDKRLKLVGTIS

Sequences:

>Translated_697_residues
MSARPAPMNARRVMELLRNGLGAPLALMAMLAMLMVPLAAPVLDALFTFNIAISLMVLLAVVYVQRPLEFTIFPIVLLMT
TMLRLALNVASSRVILINGQDGHAAAGKVIEAFGQFVIGGNYAVGIVVFAILTIINFVVITKGAGRVSEVTARFILDAMP
GKQMAIDADLNAGLLTREEAKARREEVREEADFYGAMDGANKFIRGDAIAAILILFINLIGGMAVGMLQHGMSFMDAAST
YTLLSIGDGLVAQLPALLVSSSVALLVTRASRAQDMRGAMVSQVFGQHRALAVAAAILGLVGLVPGMPNVAFLTLGLVLG
VIAWKLYKRSLAKPAAGDPAADPQAAAAATAAQASAELSWDELRPIDPLGLEVGYRLIPLVDKNQGGELMARIKGVRRKL
TQDIGFLVPPVHIRDNLELSANAYRLLVHGVPVATAEIYSDRELALDPGGALGQLDGIPGKDPAFGLDATWIQPHQRAYA
ESMGYTVVDPATVVATHLSHLIREHAPELLGHEEVQQLLATLAKTAPKMVEDLTPKALPLSVVVRVLQNLLIEKIPVRQL
RKIVEALVEHAPHSQDPATLTAAVRTSLGRFIVQEIAGMSAELPVFTLAPQLERVLQESTHGNGVALEPGLAERLHQSLA
DCVGKQEARNEPAVVLVPGQVRAALARLVRHSVPSLSVLAYSEVPEDKRLKLVGTIS
>Mature_696_residues
SARPAPMNARRVMELLRNGLGAPLALMAMLAMLMVPLAAPVLDALFTFNIAISLMVLLAVVYVQRPLEFTIFPIVLLMTT
MLRLALNVASSRVILINGQDGHAAAGKVIEAFGQFVIGGNYAVGIVVFAILTIINFVVITKGAGRVSEVTARFILDAMPG
KQMAIDADLNAGLLTREEAKARREEVREEADFYGAMDGANKFIRGDAIAAILILFINLIGGMAVGMLQHGMSFMDAASTY
TLLSIGDGLVAQLPALLVSSSVALLVTRASRAQDMRGAMVSQVFGQHRALAVAAAILGLVGLVPGMPNVAFLTLGLVLGV
IAWKLYKRSLAKPAAGDPAADPQAAAAATAAQASAELSWDELRPIDPLGLEVGYRLIPLVDKNQGGELMARIKGVRRKLT
QDIGFLVPPVHIRDNLELSANAYRLLVHGVPVATAEIYSDRELALDPGGALGQLDGIPGKDPAFGLDATWIQPHQRAYAE
SMGYTVVDPATVVATHLSHLIREHAPELLGHEEVQQLLATLAKTAPKMVEDLTPKALPLSVVVRVLQNLLIEKIPVRQLR
KIVEALVEHAPHSQDPATLTAAVRTSLGRFIVQEIAGMSAELPVFTLAPQLERVLQESTHGNGVALEPGLAERLHQSLAD
CVGKQEARNEPAVVLVPGQVRAALARLVRHSVPSLSVLAYSEVPEDKRLKLVGTIS

Specific function: Required for formation of the rod structure of the flagellar apparatus. Together with fliI and fliH, may constitute the export apparatus of flagellin [H]

COG id: COG1298

COG function: function code NU; Flagellar biosynthesis pathway, component FlhA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family [H]

Homologues:

Organism=Escherichia coli, GI1788187, Length=676, Percent_Identity=52.2189349112426, Blast_Score=669, Evalue=0.0,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006301
- InterPro:   IPR001712 [H]

Pfam domain/function: PF00771 FHIPEP [H]

EC number: NA

Molecular weight: Translated: 74323; Mature: 74192

Theoretical pI: Translated: 7.10; Mature: 7.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSARPAPMNARRVMELLRNGLGAPLALMAMLAMLMVPLAAPVLDALFTFNIAISLMVLLA
CCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VVYVQRPLEFTIFPIVLLMTTMLRLALNVASSRVILINGQDGHAAAGKVIEAFGQFVIGG
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHCCCEECC
NYAVGIVVFAILTIINFVVITKGAGRVSEVTARFILDAMPGKQMAIDADLNAGLLTREEA
CHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCHHHH
KARREEVREEADFYGAMDGANKFIRGDAIAAILILFINLIGGMAVGMLQHGMSFMDAAST
HHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH
YTLLSIGDGLVAQLPALLVSSSVALLVTRASRAQDMRGAMVSQVFGQHRALAVAAAILGL
EEHEECCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGLVPGMPNVAFLTLGLVLGVIAWKLYKRSLAKPAAGDPAADPQAAAAATAAQASAELSW
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCH
DELRPIDPLGLEVGYRLIPLVDKNQGGELMARIKGVRRKLTQDIGFLVPPVHIRDNLELS
HHCCCCCCCCHHCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCEEC
ANAYRLLVHGVPVATAEIYSDRELALDPGGALGQLDGIPGKDPAFGLDATWIQPHQRAYA
CCCEEEEEECCCHHHHHHHCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHH
ESMGYTVVDPATVVATHLSHLIREHAPELLGHEEVQQLLATLAKTAPKMVEDLTPKALPL
HHCCCEEECHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
SVVVRVLQNLLIEKIPVRQLRKIVEALVEHAPHSQDPATLTAAVRTSLGRFIVQEIAGMS
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
AELPVFTLAPQLERVLQESTHGNGVALEPGLAERLHQSLADCVGKQEARNEPAVVLVPGQ
CCCCHHHHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHHHHHCHHHHCCCCEEEEECCH
VRAALARLVRHSVPSLSVLAYSEVPEDKRLKLVGTIS
HHHHHHHHHHHCCCCCEEEEECCCCCCCCEEEEEECC
>Mature Secondary Structure 
SARPAPMNARRVMELLRNGLGAPLALMAMLAMLMVPLAAPVLDALFTFNIAISLMVLLA
CCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VVYVQRPLEFTIFPIVLLMTTMLRLALNVASSRVILINGQDGHAAAGKVIEAFGQFVIGG
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHCCCEECC
NYAVGIVVFAILTIINFVVITKGAGRVSEVTARFILDAMPGKQMAIDADLNAGLLTREEA
CHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCHHHH
KARREEVREEADFYGAMDGANKFIRGDAIAAILILFINLIGGMAVGMLQHGMSFMDAAST
HHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH
YTLLSIGDGLVAQLPALLVSSSVALLVTRASRAQDMRGAMVSQVFGQHRALAVAAAILGL
EEHEECCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGLVPGMPNVAFLTLGLVLGVIAWKLYKRSLAKPAAGDPAADPQAAAAATAAQASAELSW
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCH
DELRPIDPLGLEVGYRLIPLVDKNQGGELMARIKGVRRKLTQDIGFLVPPVHIRDNLELS
HHCCCCCCCCHHCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCEEC
ANAYRLLVHGVPVATAEIYSDRELALDPGGALGQLDGIPGKDPAFGLDATWIQPHQRAYA
CCCEEEEEECCCHHHHHHHCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHH
ESMGYTVVDPATVVATHLSHLIREHAPELLGHEEVQQLLATLAKTAPKMVEDLTPKALPL
HHCCCEEECHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
SVVVRVLQNLLIEKIPVRQLRKIVEALVEHAPHSQDPATLTAAVRTSLGRFIVQEIAGMS
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
AELPVFTLAPQLERVLQESTHGNGVALEPGLAERLHQSLADCVGKQEARNEPAVVLVPGQ
CCCCHHHHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHHHHHCHHHHCCCCEEEEECCH
VRAALARLVRHSVPSLSVLAYSEVPEDKRLKLVGTIS
HHHHHHHHHHHCCCCCEEEEECCCCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]