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The map label for this gene is cheA1 [H]

Identifier: 78047512

GI number: 78047512

Start: 2229993

End: 2232002

Strand: Reverse

Name: cheA1 [H]

Synonym: XCV1956

Alternate gene names: 78047512

Gene position: 2232002-2229993 (Counterclockwise)

Preceding gene: 78047513

Following gene: 78047511

Centisome position: 43.1

GC content: 66.22

Gene sequence:

>2010_bases
ATGAGCATGGACCTGCAACGTTTCCACGCCACCTTTTTCGAGGAAAGCCGTGAAGGGCTCGACGCGATGGAGGCCGGGCT
GCTGTCGCTTGAAGAAGGCAACCGCGACCCGGAAATCATCAACTCGGTGTTCCGCGCCGCGCACTCGATCAAGGGCGGCG
CTGCCACCTTCGGTTTCGACGCCGTCGCAGGGCTGACCCACGTGCTGGAGACGCTGCTGGACGAGCTGCGCTCCAACAAG
CGCCAGCTCGAACCCAATGCGGTCGATGCCATGCTTGGCTCGGTCGATGTGCTGCGCGCCCTGTTGCGCGAAGCCGAACA
CGGCACCCCGGCCGATCCGGCTGCGGTCAAGGCCGTGCACACCCGGTTGAATGCCGTGCTCGCTGGCGAAGCGCCGGCCG
CCGCGGCGGTCGCCAAGCCCAAGGAAGAAGAACCCGAAGCCTGGCATATCGGTTTCACCCCGGCGCCGTCGCTGTTCATG
AGCGGCAACGACCCGCTGCGCATCATCCGTGAGCTCGAGCACCTGGGCCCGCTGCAGATTGCCGCACGCCTGGAGCGCAT
GCCGGGTTTTGAAAACATCGACCCGCTGGAAGCCTACCTGGCCTGGGATCTGGGCCTGATCGGCAAGATTCCGCGCAGCA
AGATCGAAGACACCTTCGCCTGGGTGGTGGACGATTGCGAGCTGGACATCCGCCCGATGGCGGTGCCCGGCCCGCCGCCG
AGCCTGGCCGTGGACGCTCCGGCGGCCGCACCGGTTGCAGCCGTTGCCGCTGCACCGGGCGCCGCTGCCGAACCTGCTGC
CGCCGCGGCGACACCGGCCAAGGCCGCCGCTGCCGAAGCCGAAAGCTCGATCCGCGTCAGCGTCGACAAGGTCGATGCAT
TGATCAATCTGGTCGGCGAACTGGTGATCACCCAGGCCATGCTCAAGCAGGTCTCCACCGGCCTGGACCCGGCGCATGCC
GAACAGCTGTTCGCCGGCCTGGATCTGCTCGAGCGCAATACCCGCGATCTGCAGGAAGCGGTCATCGGCGTGCGCATGCT
GCCGGTGGATGCGGTGTTCCGCCGCTTCCCGCGCCTGGTACGCGACCTCTCCAGCCGCCTCGGCAAGCAAGTGCGCCTGC
GCACCATTGGCGAAAGCACCGAGCTGGACAAGGGCCTGATCGAAAAGATCGCCGATCCGTTGGTGCACCTGGTGCGCAAC
TCGATCGACCACGGCCTGGAAATGCCCGATGCGCGCCGCGCCTCCGGCAAGGACGAAACCGGCACGATTACCCTGGCGGC
ATCGCACCAGGGTGGCCACATCGTGATCGAAGTCAGCGACGACGGCCGCGGTCTCAATCGCGCCAAGATCCTGGAAAAAG
CGGCCGAACGCGGCATCGCCGTGCCGGACAACCCGACCGATGCGCAGGTGTGGGACTTGATCTTCGCACCGGGCTTCTCC
ACCGCCGATGCGGTGACCGACCTGTCCGGTCGTGGCGTGGGCATGGACGTGGTCCGCCGCAACATCCAGGGCTTAGGGGG
CGAAGTGCAGCTGGAAAGCAACGCCGGCAGCGGTACCCGCGTGTTGATCCGCCTGCCGCTGACCCTGGCCATTCTGGACG
GCATGACCGTTTCGGTCGCCGGCGAAACCCTGATCCTGCCGCTGTCCTACGTGCTTGAAGCCCTGCAGCCGGCACCGGAA
GACGTCCGCGCGATGGCCGGCGACGGTCGGGTATTGCGGGTGCGTGGCGAATATCTGCCGATCCTCTCGCTCACCAATTA
CTACGGCTTCGGCGGGCAACAGTCCTCCAAGGAATCGCTGGTGGTGGTGGTCGAAGGCGACGGCCAGAAGATCGCGCTGG
AAGTGGACGAGTTGCTCGGCCAGCAGCAGGTGGTGGTCAAGAACATCGAGAACAATTACCGCCGCATCCCGGGCGTTTCC
GGCGCCACCATCCTCGGCGATGGGCGGGTCTCGCTGATCGTGGACATCGGTGGACTGGTGCGCTCGCTCAAGGTACCGCA
AGCCGCGTAA

Upstream 100 bases:

>100_bases
CGGTTGGCTGGTCAAGCCGTTCAACCCAGAACAGCTGATCGCCACCGTGCAGAAAGTTCTCGGTTAAACCCTCCTCGCTT
CAGCTTCGGATTTCACGCCC

Downstream 100 bases:

>100_bases
TGCACTCGCCGCGGCGTGGATGCCGCGGCGCAAGGCTCCACCACGCCATCGATGCACGATGGGTGCTGGAGCGATCGCCG
GCAGTATGGGGACTGCCGGC

Product: chemotaxis protein CheA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 669; Mature: 668

Protein sequence:

>669_residues
MSMDLQRFHATFFEESREGLDAMEAGLLSLEEGNRDPEIINSVFRAAHSIKGGAATFGFDAVAGLTHVLETLLDELRSNK
RQLEPNAVDAMLGSVDVLRALLREAEHGTPADPAAVKAVHTRLNAVLAGEAPAAAAVAKPKEEEPEAWHIGFTPAPSLFM
SGNDPLRIIRELEHLGPLQIAARLERMPGFENIDPLEAYLAWDLGLIGKIPRSKIEDTFAWVVDDCELDIRPMAVPGPPP
SLAVDAPAAAPVAAVAAAPGAAAEPAAAAATPAKAAAAEAESSIRVSVDKVDALINLVGELVITQAMLKQVSTGLDPAHA
EQLFAGLDLLERNTRDLQEAVIGVRMLPVDAVFRRFPRLVRDLSSRLGKQVRLRTIGESTELDKGLIEKIADPLVHLVRN
SIDHGLEMPDARRASGKDETGTITLAASHQGGHIVIEVSDDGRGLNRAKILEKAAERGIAVPDNPTDAQVWDLIFAPGFS
TADAVTDLSGRGVGMDVVRRNIQGLGGEVQLESNAGSGTRVLIRLPLTLAILDGMTVSVAGETLILPLSYVLEALQPAPE
DVRAMAGDGRVLRVRGEYLPILSLTNYYGFGGQQSSKESLVVVVEGDGQKIALEVDELLGQQQVVVKNIENNYRRIPGVS
GATILGDGRVSLIVDIGGLVRSLKVPQAA

Sequences:

>Translated_669_residues
MSMDLQRFHATFFEESREGLDAMEAGLLSLEEGNRDPEIINSVFRAAHSIKGGAATFGFDAVAGLTHVLETLLDELRSNK
RQLEPNAVDAMLGSVDVLRALLREAEHGTPADPAAVKAVHTRLNAVLAGEAPAAAAVAKPKEEEPEAWHIGFTPAPSLFM
SGNDPLRIIRELEHLGPLQIAARLERMPGFENIDPLEAYLAWDLGLIGKIPRSKIEDTFAWVVDDCELDIRPMAVPGPPP
SLAVDAPAAAPVAAVAAAPGAAAEPAAAAATPAKAAAAEAESSIRVSVDKVDALINLVGELVITQAMLKQVSTGLDPAHA
EQLFAGLDLLERNTRDLQEAVIGVRMLPVDAVFRRFPRLVRDLSSRLGKQVRLRTIGESTELDKGLIEKIADPLVHLVRN
SIDHGLEMPDARRASGKDETGTITLAASHQGGHIVIEVSDDGRGLNRAKILEKAAERGIAVPDNPTDAQVWDLIFAPGFS
TADAVTDLSGRGVGMDVVRRNIQGLGGEVQLESNAGSGTRVLIRLPLTLAILDGMTVSVAGETLILPLSYVLEALQPAPE
DVRAMAGDGRVLRVRGEYLPILSLTNYYGFGGQQSSKESLVVVVEGDGQKIALEVDELLGQQQVVVKNIENNYRRIPGVS
GATILGDGRVSLIVDIGGLVRSLKVPQAA
>Mature_668_residues
SMDLQRFHATFFEESREGLDAMEAGLLSLEEGNRDPEIINSVFRAAHSIKGGAATFGFDAVAGLTHVLETLLDELRSNKR
QLEPNAVDAMLGSVDVLRALLREAEHGTPADPAAVKAVHTRLNAVLAGEAPAAAAVAKPKEEEPEAWHIGFTPAPSLFMS
GNDPLRIIRELEHLGPLQIAARLERMPGFENIDPLEAYLAWDLGLIGKIPRSKIEDTFAWVVDDCELDIRPMAVPGPPPS
LAVDAPAAAPVAAVAAAPGAAAEPAAAAATPAKAAAAEAESSIRVSVDKVDALINLVGELVITQAMLKQVSTGLDPAHAE
QLFAGLDLLERNTRDLQEAVIGVRMLPVDAVFRRFPRLVRDLSSRLGKQVRLRTIGESTELDKGLIEKIADPLVHLVRNS
IDHGLEMPDARRASGKDETGTITLAASHQGGHIVIEVSDDGRGLNRAKILEKAAERGIAVPDNPTDAQVWDLIFAPGFST
ADAVTDLSGRGVGMDVVRRNIQGLGGEVQLESNAGSGTRVLIRLPLTLAILDGMTVSVAGETLILPLSYVLEALQPAPED
VRAMAGDGRVLRVRGEYLPILSLTNYYGFGGQQSSKESLVVVVEGDGQKIALEVDELLGQQQVVVKNIENNYRRIPGVSG
ATILGDGRVSLIVDIGGLVRSLKVPQAA

Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY [H]

COG id: COG0643

COG function: function code NT; Chemotaxis protein histidine kinase and related kinases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HPt domain [H]

Homologues:

Organism=Escherichia coli, GI1788197, Length=669, Percent_Identity=45.5904334828102, Blast_Score=541, Evalue=1e-155,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR002545
- InterPro:   IPR015162
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR004105
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01584 CheW; PF09078 CheY-binding; PF02895 H-kinase_dim; PF02518 HATPase_c; PF01627 Hpt [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 71112; Mature: 70981

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: PS50851 CHEW ; PS50894 HPT ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSMDLQRFHATFFEESREGLDAMEAGLLSLEEGNRDPEIINSVFRAAHSIKGGAATFGFD
CCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCHH
AVAGLTHVLETLLDELRSNKRQLEPNAVDAMLGSVDVLRALLREAEHGTPADPAAVKAVH
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHCCCCCCCHHHHHHHH
TRLNAVLAGEAPAAAAVAKPKEEEPEAWHIGFTPAPSLFMSGNDPLRIIRELEHLGPLQI
HHHHHHEECCCCCHHHHCCCCCCCCCEEEECCCCCCCEEECCCCHHHHHHHHHHCCHHHH
AARLERMPGFENIDPLEAYLAWDLGLIGKIPRSKIEDTFAWVVDDCELDIRPMAVPGPPP
HHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHEEEECCCCCEEEEECCCCCC
SLAVDAPAAAPVAAVAAAPGAAAEPAAAAATPAKAAAAEAESSIRVSVDKVDALINLVGE
CCEECCCCCCCHHHHHCCCCCCCCCCHHHCCCHHHHHHHCCCCEEEEHHHHHHHHHHHHH
LVITQAMLKQVSTGLDPAHAEQLFAGLDLLERNTRDLQEAVIGVRMLPVDAVFRRFPRLV
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHH
RDLSSRLGKQVRLRTIGESTELDKGLIEKIADPLVHLVRNSIDHGLEMPDARRASGKDET
HHHHHHHCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
GTITLAASHQGGHIVIEVSDDGRGLNRAKILEKAAERGIAVPDNPTDAQVWDLIFAPGFS
CEEEEEEECCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHEEECCCCC
TADAVTDLSGRGVGMDVVRRNIQGLGGEVQLESNAGSGTRVLIRLPLTLAILDGMTVSVA
CHHHHHCCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCEEEEECCHHHHHHCCCEEEEC
GETLILPLSYVLEALQPAPEDVRAMAGDGRVLRVRGEYLPILSLTNYYGFGGQQSSKESL
CCEEEEEHHHHHHHHCCCCHHHHHHCCCCCEEEECCCEECEEEECCCCCCCCCCCCCCCE
VVVVEGDGQKIALEVDELLGQQQVVVKNIENNYRRIPGVSGATILGDGRVSLIVDIGGLV
EEEEECCCCEEEEEHHHHCCCHHHHHHHHHHHHHCCCCCCCCEEEECCCEEEEEEHHHHH
RSLKVPQAA
HHCCCCCCC
>Mature Secondary Structure 
SMDLQRFHATFFEESREGLDAMEAGLLSLEEGNRDPEIINSVFRAAHSIKGGAATFGFD
CCCHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCHH
AVAGLTHVLETLLDELRSNKRQLEPNAVDAMLGSVDVLRALLREAEHGTPADPAAVKAVH
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHCCCCCCCHHHHHHHH
TRLNAVLAGEAPAAAAVAKPKEEEPEAWHIGFTPAPSLFMSGNDPLRIIRELEHLGPLQI
HHHHHHEECCCCCHHHHCCCCCCCCCEEEECCCCCCCEEECCCCHHHHHHHHHHCCHHHH
AARLERMPGFENIDPLEAYLAWDLGLIGKIPRSKIEDTFAWVVDDCELDIRPMAVPGPPP
HHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHEEEECCCCCEEEEECCCCCC
SLAVDAPAAAPVAAVAAAPGAAAEPAAAAATPAKAAAAEAESSIRVSVDKVDALINLVGE
CCEECCCCCCCHHHHHCCCCCCCCCCHHHCCCHHHHHHHCCCCEEEEHHHHHHHHHHHHH
LVITQAMLKQVSTGLDPAHAEQLFAGLDLLERNTRDLQEAVIGVRMLPVDAVFRRFPRLV
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHH
RDLSSRLGKQVRLRTIGESTELDKGLIEKIADPLVHLVRNSIDHGLEMPDARRASGKDET
HHHHHHHCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
GTITLAASHQGGHIVIEVSDDGRGLNRAKILEKAAERGIAVPDNPTDAQVWDLIFAPGFS
CEEEEEEECCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHEEECCCCC
TADAVTDLSGRGVGMDVVRRNIQGLGGEVQLESNAGSGTRVLIRLPLTLAILDGMTVSVA
CHHHHHCCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCEEEEECCHHHHHHCCCEEEEC
GETLILPLSYVLEALQPAPEDVRAMAGDGRVLRVRGEYLPILSLTNYYGFGGQQSSKESL
CCEEEEEHHHHHHHHCCCCHHHHHHCCCCCEEEECCCEECEEEECCCCCCCCCCCCCCCE
VVVVEGDGQKIALEVDELLGQQQVVVKNIENNYRRIPGVSGATILGDGRVSLIVDIGGLV
EEEEECCCCEEEEEHHHHCCCHHHHHHHHHHHHHCCCCCCCCEEEECCCEEEEEEHHHHH
RSLKVPQAA
HHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2002011; 9097040; 9278503; 3510184; 2832069; 2068106; 8555213; 8639521; 9020767; 9437425; 9636149 [H]