Click here to switch to the map view.

The map label for this gene is mtnD [H]

Identifier: 78047441

GI number: 78047441

Start: 2132021

End: 2132587

Strand: Reverse

Name: mtnD [H]

Synonym: XCV1885

Alternate gene names: 78047441

Gene position: 2132587-2132021 (Counterclockwise)

Preceding gene: 78047442

Following gene: 78047440

Centisome position: 41.18

GC content: 62.08

Gene sequence:

>567_bases
ATGAGCCGACTGCGTATCTTTGCCGACACCAATCCCGCCACTCCCGAGTTTGATAGCCGCGACGGCGATGCGATCGCCGC
TCAGTTGCAGAAGATTGGCGTGACCTTCGAACGCTGGCATGCCAGCGCGCCGGTCGAACCGGGCGCCACGCCCGAGCAGG
TGATGGACGCCTACCGTGCCGATATCGATCGCATCAGCGCCGAGCGCGGCTTCAAGACCGTGGACGTGGTCAGCATCGCG
CCGGACAACCCCAAGCGCGAAGAAATGCGCGCCAAGTTTCTGGACGAGCACTTCCACAAGGAAGACGAGGTGCGGTTCTT
CGTCGCCGGCTCAGGCCTGTTTACGCTGCACGTCGATGCCAAGGTTTATGAGATCGAATGCGTCAAGGACGACCTGATTG
CCGTGCCTGACGGCACCCTGCACTGGTTCGACATGGGGCCGGAACCGCACTTTGTGGCGATCCGCTTCTTCACCGAGCCG
GACGGCTGGGTCGGACATTTCACCGGCACCGAAATCGCCAAACAATTCCCCCGCTACGCCCCCGAGAAACCTCACAAGGC
CAGCTGA

Upstream 100 bases:

>100_bases
TGGAAGCGTTCGAATTCCTGCTGCATTGCGAACTCGAACTGCTGAAACTGCGCGGCACGCGCTGAGTACTGTCCGTCCCC
CATTCGTGAGCCAGACCGCC

Downstream 100 bases:

>100_bases
CGATGACACGACCGCAAGCGATCCTCACCGATATCGAAGGTACGACCAGCAGCATTTCGTTCGTCAAGGACGTCTTGTTC
CCGTATGCGCGCCGCGCCAT

Product: acireductone dioxygenase family protein

Products: NA

Alternate protein names: 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; DHK-MTPene dioxygenase; Acireductone dioxygenase (Fe(2+)-requiring); ARD'; Fe-ARD; Acireductone dioxygenase (Ni(2+)-requiring); ARD; Ni-ARD [H]

Number of amino acids: Translated: 188; Mature: 187

Protein sequence:

>188_residues
MSRLRIFADTNPATPEFDSRDGDAIAAQLQKIGVTFERWHASAPVEPGATPEQVMDAYRADIDRISAERGFKTVDVVSIA
PDNPKREEMRAKFLDEHFHKEDEVRFFVAGSGLFTLHVDAKVYEIECVKDDLIAVPDGTLHWFDMGPEPHFVAIRFFTEP
DGWVGHFTGTEIAKQFPRYAPEKPHKAS

Sequences:

>Translated_188_residues
MSRLRIFADTNPATPEFDSRDGDAIAAQLQKIGVTFERWHASAPVEPGATPEQVMDAYRADIDRISAERGFKTVDVVSIA
PDNPKREEMRAKFLDEHFHKEDEVRFFVAGSGLFTLHVDAKVYEIECVKDDLIAVPDGTLHWFDMGPEPHFVAIRFFTEP
DGWVGHFTGTEIAKQFPRYAPEKPHKAS
>Mature_187_residues
SRLRIFADTNPATPEFDSRDGDAIAAQLQKIGVTFERWHASAPVEPGATPEQVMDAYRADIDRISAERGFKTVDVVSIAP
DNPKREEMRAKFLDEHFHKEDEVRFFVAGSGLFTLHVDAKVYEIECVKDDLIAVPDGTLHWFDMGPEPHFVAIRFFTEPD
GWVGHFTGTEIAKQFPRYAPEKPHKAS

Specific function: Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- me

COG id: COG1791

COG function: function code S; Uncharacterized conserved protein, contains double-stranded beta-helix domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acireductone dioxygenase (ARD) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004313
- InterPro:   IPR011051
- InterPro:   IPR014710 [H]

Pfam domain/function: PF03079 ARD [H]

EC number: =1.13.11.54; =1.13.11.53 [H]

Molecular weight: Translated: 21259; Mature: 21128

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRLRIFADTNPATPEFDSRDGDAIAAQLQKIGVTFERWHASAPVEPGATPEQVMDAYRA
CCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHCCCCCCCCCCCHHHHHHHHHH
DIDRISAERGFKTVDVVSIAPDNPKREEMRAKFLDEHFHKEDEVRFFVAGSGLFTLHVDA
HHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCEEEEEECC
KVYEIECVKDDLIAVPDGTLHWFDMGPEPHFVAIRFFTEPDGWVGHFTGTEIAKQFPRYA
EEEEEEEECCCEEECCCCCEEEEECCCCCCEEEEEEEECCCCCEEECCHHHHHHHHHCCC
PEKPHKAS
CCCCCCCC
>Mature Secondary Structure 
SRLRIFADTNPATPEFDSRDGDAIAAQLQKIGVTFERWHASAPVEPGATPEQVMDAYRA
CCEEEEECCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHCCCCCCCCCCCHHHHHHHHHH
DIDRISAERGFKTVDVVSIAPDNPKREEMRAKFLDEHFHKEDEVRFFVAGSGLFTLHVDA
HHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCEEEEEECC
KVYEIECVKDDLIAVPDGTLHWFDMGPEPHFVAIRFFTEPDGWVGHFTGTEIAKQFPRYA
EEEEEEEECCCEEECCCCCEEEEECCCCCCEEEEEEEECCCCCEEECCHHHHHHHHHCCC
PEKPHKAS
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]