Click here to switch to the map view.

The map label for this gene is tesB [H]

Identifier: 78046834

GI number: 78046834

Start: 1435290

End: 1435514

Strand: Reverse

Name: tesB [H]

Synonym: XCV1278

Alternate gene names: 78046834

Gene position: 1435514-1435290 (Counterclockwise)

Preceding gene: 78046835

Following gene: 78046833

Centisome position: 27.72

GC content: 67.56

Gene sequence:

>225_bases
GTGCAGATGGCCTCGCTCGATCATGCCCTGTGGTTCCATCGCCCATTCCGTACCGACGACTGGCTGCTGTACTCGCTCGA
CAGCCCCACCGCGCAAGGGTCACGCGGCCTGGCCCGCGGGCAGTTTTTCACCCGCGACGGCGTGCTGGTGGCAAGCACCA
CGCAGGAAGGCCTGATCCGGGTGGTGCCTGACGGCAGCGCGATTGCCGTGCCGGCCAAGGAGTAG

Upstream 100 bases:

>100_bases
CGATGTGGGCCTGCATCAAGCGCTGCTTGCGTACGCGTCGGATTTTCAGTTGCTCGGTACCTCGACATTTCCGCACGGCA
TCAGCTATTAGACGCCGAAC

Downstream 100 bases:

>100_bases
ACCTCACGCCGCGACGGTAAGGCACGCTGCTTGATGCCAGCACGCACCCTTGGCCGGGTCGAAGGCAGCCGAGCAACGCG
CCCCGCGCACTGCAGACGCC

Product: putative acyl-CoA thiolesterase (fragment)

Products: Hydrolyzed acyl-CoA thioesters [C]

Alternate protein names: Acyl-CoA thioesterase II; TEII [H]

Number of amino acids: Translated: 74; Mature: 74

Protein sequence:

>74_residues
MQMASLDHALWFHRPFRTDDWLLYSLDSPTAQGSRGLARGQFFTRDGVLVASTTQEGLIRVVPDGSAIAVPAKE

Sequences:

>Translated_74_residues
MQMASLDHALWFHRPFRTDDWLLYSLDSPTAQGSRGLARGQFFTRDGVLVASTTQEGLIRVVPDGSAIAVPAKE
>Mature_74_residues
MQMASLDHALWFHRPFRTDDWLLYSLDSPTAQGSRGLARGQFFTRDGVLVASTTQEGLIRVVPDGSAIAVPAKE

Specific function: Can hydrolyze a broad range of acyl-CoA thioesters. Its physiological function is not known [H]

COG id: COG1946

COG function: function code I; Acyl-CoA thioesterase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the C/M/P thioester hydrolase family [H]

Homologues:

Organism=Homo sapiens, GI34577075, Length=64, Percent_Identity=56.25, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI1786657, Length=60, Percent_Identity=58.3333333333333, Blast_Score=90, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17558508, Length=70, Percent_Identity=51.4285714285714, Blast_Score=66, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI115532456, Length=61, Percent_Identity=49.1803278688525, Blast_Score=65, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17531885, Length=61, Percent_Identity=49.1803278688525, Blast_Score=65, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17531889, Length=61, Percent_Identity=49.1803278688525, Blast_Score=65, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71988741, Length=57, Percent_Identity=50.8771929824561, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003703 [H]

Pfam domain/function: PF02551 Acyl_CoA_thio [H]

EC number: 3.1.2.- [C]

Molecular weight: Translated: 8160; Mature: 8160

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQMASLDHALWFHRPFRTDDWLLYSLDSPTAQGSRGLARGQFFTRDGVLVASTTQEGLIR
CCCCCCCCEEEECCCCCCCCEEEEECCCCCCCCCCCCCCCEEECCCCEEEEECCCCCEEE
VVPDGSAIAVPAKE
ECCCCCEEEEECCC
>Mature Secondary Structure
MQMASLDHALWFHRPFRTDDWLLYSLDSPTAQGSRGLARGQFFTRDGVLVASTTQEGLIR
CCCCCCCCEEEECCCCCCCCEEEEECCCCCCCCCCCCCCCEEECCCCEEEEECCCCCEEE
VVPDGSAIAVPAKE
ECCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA thioesters [C]

Specific reaction: Hydrolyzes a broad range of acyl-CoA thioesters [C]

General reaction: Hydrolase; Acting on ester bonds; Thiolester hydrolases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]