Click here to switch to the map view.

The map label for this gene is minD [H]

Identifier: 78046813

GI number: 78046813

Start: 1416656

End: 1417465

Strand: Reverse

Name: minD [H]

Synonym: XCV1257

Alternate gene names: 78046813

Gene position: 1417465-1416656 (Counterclockwise)

Preceding gene: 78046814

Following gene: 78046812

Centisome position: 27.37

GC content: 63.83

Gene sequence:

>810_bases
TTGGCTGAAATCATCGTAGTCACCTCCGGCAAGGGCGGCGTCGGCAAGACCACCACCAGCGCAAGCCTGGCTTGCGGGCT
GGCCAAACGCGGCAAGAAGGTGGCGGTCATCGACTTCGACGTCGGCTTGCGCAACCTGGACCTGATCATGGGCTGCGAGC
GGCGCGTGGTGTACGACTTCGTCAATGTCGTGCACGGCGAAGCCACGCTCAAGCAGTCGCTGATCAAGGACAAGCGGTTC
GAGAACCTGTACGTCCTGGCCGCCTCGCAGACCCGCGACAAGGACGCGCTGACCCAGGAAGGCGTGGAAAAGGTGCTCAA
GGACCTAGCCGCCGACGGCTTCGACTACATCGTCTGCGATTCGCCGGCCGGCATCGAAAAAGGCGCGTTCCTGGCGATGT
ATTTCGCCGACCGCGCGGTGGTGGTGGTCAATCCGGAAGTCTCTTCGGTGCGCGACTCGGACCGCATCATCGGCCTGCTC
GATTCCAAGACCCGCAAGGCCGAAGAAGGCAAGGCCGTGCCGGCGTTCCTGCTGCTGACCCGCTACAGCCCGGGCCGCGT
GGAAGGCGGCGAGATGCTCAGCATCACCGACGTGGAAGAAGTGCTGGGCCTGAAGGCGATCGGCGTGATTCCCGAATCCG
GCGACGTGCTCAACGCCTCCAACAAGGGCGAGCCGGTGATCCTGGATGCCGAGTCCCCGGCCGGCCAGGCGTATGACGAC
GCAGTCGCCCGCATCATGGGCGAGGAGCGCCCGATGCGATTCACATCCGTGGAGAAGAAAGGCTTCTTCAGCAAGCTGTT
CGGAGGGTAA

Upstream 100 bases:

>100_bases
TGCGTGGCAAGGCCGTCCAGGTCTGGCTGGAGCAGGATCAGATCAAGATCGCTGCGCTTGATTGACGCGGCCCAACCACA
GAAATATTCGGAGAAATCCT

Downstream 100 bases:

>100_bases
GCATGGGCCTGCTCGATTTTCTCAAGAGCAAGAAAAACACCGCCGAGACGGCCAAGAACCGCCTGCAGATCATCATTGCG
CAGGAGCGCAACCACCGCGG

Product: septum site-determining protein (cell division inhibitor) MinD

Products: NA

Alternate protein names: Cell division inhibitor minD [H]

Number of amino acids: Translated: 269; Mature: 268

Protein sequence:

>269_residues
MAEIIVVTSGKGGVGKTTTSASLACGLAKRGKKVAVIDFDVGLRNLDLIMGCERRVVYDFVNVVHGEATLKQSLIKDKRF
ENLYVLAASQTRDKDALTQEGVEKVLKDLAADGFDYIVCDSPAGIEKGAFLAMYFADRAVVVVNPEVSSVRDSDRIIGLL
DSKTRKAEEGKAVPAFLLLTRYSPGRVEGGEMLSITDVEEVLGLKAIGVIPESGDVLNASNKGEPVILDAESPAGQAYDD
AVARIMGEERPMRFTSVEKKGFFSKLFGG

Sequences:

>Translated_269_residues
MAEIIVVTSGKGGVGKTTTSASLACGLAKRGKKVAVIDFDVGLRNLDLIMGCERRVVYDFVNVVHGEATLKQSLIKDKRF
ENLYVLAASQTRDKDALTQEGVEKVLKDLAADGFDYIVCDSPAGIEKGAFLAMYFADRAVVVVNPEVSSVRDSDRIIGLL
DSKTRKAEEGKAVPAFLLLTRYSPGRVEGGEMLSITDVEEVLGLKAIGVIPESGDVLNASNKGEPVILDAESPAGQAYDD
AVARIMGEERPMRFTSVEKKGFFSKLFGG
>Mature_268_residues
AEIIVVTSGKGGVGKTTTSASLACGLAKRGKKVAVIDFDVGLRNLDLIMGCERRVVYDFVNVVHGEATLKQSLIKDKRFE
NLYVLAASQTRDKDALTQEGVEKVLKDLAADGFDYIVCDSPAGIEKGAFLAMYFADRAVVVVNPEVSSVRDSDRIIGLLD
SKTRKAEEGKAVPAFLLLTRYSPGRVEGGEMLSITDVEEVLGLKAIGVIPESGDVLNASNKGEPVILDAESPAGQAYDDA
VARIMGEERPMRFTSVEKKGFFSKLFGG

Specific function: ATPase required for the correct placement of the division site. Cell division inhibitors minC and minD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to desta

COG id: COG2894

COG function: function code D; Septum formation inhibitor-activating ATPase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the parA family. MinD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787423, Length=270, Percent_Identity=69.6296296296296, Blast_Score=385, Evalue=1e-108,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002586
- InterPro:   IPR010223 [H]

Pfam domain/function: PF01656 CbiA [H]

EC number: NA

Molecular weight: Translated: 28869; Mature: 28738

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEIIVVTSGKGGVGKTTTSASLACGLAKRGKKVAVIDFDVGLRNLDLIMGCERRVVYDF
CCEEEEEECCCCCCCCCCCCHHHHHHHHHCCCEEEEEEECCCCCCCHHHHCCCHHHHHHH
VNVVHGEATLKQSLIKDKRFENLYVLAASQTRDKDALTQEGVEKVLKDLAADGFDYIVCD
HHHHCCHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEC
SPAGIEKGAFLAMYFADRAVVVVNPEVSSVRDSDRIIGLLDSKTRKAEEGKAVPAFLLLT
CCCCCCCCCEEEEEECCCEEEEECCCHHHCCCCCCEEEEECCCCCCCCCCCCCEEEEEEE
RYSPGRVEGGEMLSITDVEEVLGLKAIGVIPESGDVLNASNKGEPVILDAESPAGQAYDD
ECCCCCCCCCCEEEEECHHHHHCEEEEEECCCCCCEECCCCCCCEEEEECCCCCCCHHHH
AVARIMGEERPMRFTSVEKKGFFSKLFGG
HHHHHHCCCCCCEEECHHHHHHHHHHHCC
>Mature Secondary Structure 
AEIIVVTSGKGGVGKTTTSASLACGLAKRGKKVAVIDFDVGLRNLDLIMGCERRVVYDF
CEEEEEECCCCCCCCCCCCHHHHHHHHHCCCEEEEEEECCCCCCCHHHHCCCHHHHHHH
VNVVHGEATLKQSLIKDKRFENLYVLAASQTRDKDALTQEGVEKVLKDLAADGFDYIVCD
HHHHCCHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEC
SPAGIEKGAFLAMYFADRAVVVVNPEVSSVRDSDRIIGLLDSKTRKAEEGKAVPAFLLLT
CCCCCCCCCEEEEEECCCEEEEECCCHHHCCCCCCEEEEECCCCCCCCCCCCCEEEEEEE
RYSPGRVEGGEMLSITDVEEVLGLKAIGVIPESGDVLNASNKGEPVILDAESPAGQAYDD
ECCCCCCCCCCEEEEECHHHHHCEEEEEECCCCCCEECCCCCCCEEEEECCCCCCCHHHH
AVARIMGEERPMRFTSVEKKGFFSKLFGG
HHHHHHCCCCCCEEECHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]