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The map label for this gene is minC [H]

Identifier: 78046814

GI number: 78046814

Start: 1417501

End: 1418247

Strand: Reverse

Name: minC [H]

Synonym: XCV1258

Alternate gene names: 78046814

Gene position: 1418247-1417501 (Counterclockwise)

Preceding gene: 78046815

Following gene: 78046813

Centisome position: 27.39

GC content: 68.54

Gene sequence:

>747_bases
GTGGCAAGTGTGAATGTGGATTTTGAACAGGCCGGCGAACTGAAGATCGGCCAGGTGGGCATCGCCAACCTGCGTGTGCG
GACGCTGGATGTGCCGCGGCTGGTGCAGGAAATGCGCGAGCGCGTGAGCCGCGCGCCCAAGTTGTTCGGCCGTGCGGCGG
TGATCCTGGATTTCGGCGGGCTGTCGCAGGTGCCGGACCTGGCTACGGCCAAGGCGCTGCTGGACGGCCTGCGCGATGCC
GGCGTGCTGCCGGTGGCGCTGGCCTACGGCACCAGCGAGATCGACCTGCTGTCCCAGCAGTTGGGCGTGCCGCTGCTGGC
CAAATTTCGCGCGCAGTACGAGCCGACCGCGGTCAGTCCGCCACCGCCACCGCCGCCGCCCGCACGTGCCGAGCCGGCAC
CGCCGGCCGCGCGACCGGCGCCGGGCCGGATGCAGCGCACCGCGGTGCGTTCGGGTCAGCAGCTGTACGCGGAGAACTGC
GACCTGACCGTACTCAGTACGGTCGGTGCCGGGGCCGAGGTCATCGCCGACGGAAGCATCCATATCTACGGTACCCTGCG
TGGCCGCGCTCTGGCCGGCGCGCAGGGCAATCCCGACGCGCGCATCTTCTGCCGCGACTTCCACGCCGAACTGGTTGCCA
TCGCTGGCCACTACAAGGTGCTGGACGATGTTCCCATGGACCTGCGTGGCAAGGCCGTCCAGGTCTGGCTGGAGCAGGAT
CAGATCAAGATCGCTGCGCTTGATTGA

Upstream 100 bases:

>100_bases
CAAGGAGACCTATGGCGGCAAGTTGCCCGACCACTTGCCGTGGGTGGGCCGGCCGCGTCATGCCGCCACCACCGCTAGCC
CATCGACGGGGAGCTGAGTT

Downstream 100 bases:

>100_bases
CGCGGCCCAACCACAGAAATATTCGGAGAAATCCTTTGGCTGAAATCATCGTAGTCACCTCCGGCAAGGGCGGCGTCGGC
AAGACCACCACCAGCGCAAG

Product: septum formation inhibitor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 248; Mature: 247

Protein sequence:

>248_residues
MASVNVDFEQAGELKIGQVGIANLRVRTLDVPRLVQEMRERVSRAPKLFGRAAVILDFGGLSQVPDLATAKALLDGLRDA
GVLPVALAYGTSEIDLLSQQLGVPLLAKFRAQYEPTAVSPPPPPPPPARAEPAPPAARPAPGRMQRTAVRSGQQLYAENC
DLTVLSTVGAGAEVIADGSIHIYGTLRGRALAGAQGNPDARIFCRDFHAELVAIAGHYKVLDDVPMDLRGKAVQVWLEQD
QIKIAALD

Sequences:

>Translated_248_residues
MASVNVDFEQAGELKIGQVGIANLRVRTLDVPRLVQEMRERVSRAPKLFGRAAVILDFGGLSQVPDLATAKALLDGLRDA
GVLPVALAYGTSEIDLLSQQLGVPLLAKFRAQYEPTAVSPPPPPPPPARAEPAPPAARPAPGRMQRTAVRSGQQLYAENC
DLTVLSTVGAGAEVIADGSIHIYGTLRGRALAGAQGNPDARIFCRDFHAELVAIAGHYKVLDDVPMDLRGKAVQVWLEQD
QIKIAALD
>Mature_247_residues
ASVNVDFEQAGELKIGQVGIANLRVRTLDVPRLVQEMRERVSRAPKLFGRAAVILDFGGLSQVPDLATAKALLDGLRDAG
VLPVALAYGTSEIDLLSQQLGVPLLAKFRAQYEPTAVSPPPPPPPPARAEPAPPAARPAPGRMQRTAVRSGQQLYAENCD
LTVLSTVGAGAEVIADGSIHIYGTLRGRALAGAQGNPDARIFCRDFHAELVAIAGHYKVLDDVPMDLRGKAVQVWLEQDQ
IKIAALD

Specific function: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize ftsZ filaments that have formed before they mature into polar Z rings. Prevents ftsZ polymerization [H]

COG id: COG0850

COG function: function code D; Septum formation inhibitor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the minC family [H]

Homologues:

Organism=Escherichia coli, GI1787424, Length=238, Percent_Identity=36.1344537815126, Blast_Score=137, Evalue=9e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016098
- InterPro:   IPR013033
- InterPro:   IPR007874
- InterPro:   IPR005526 [H]

Pfam domain/function: PF03775 MinC_C; PF05209 MinC_N [H]

EC number: NA

Molecular weight: Translated: 26406; Mature: 26275

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASVNVDFEQAGELKIGQVGIANLRVRTLDVPRLVQEMRERVSRAPKLFGRAAVILDFGG
CCCCCCCHHHCCCEEECCCCEEEEEEEEECHHHHHHHHHHHHHHHHHHHCCEEEEEECCC
LSQVPDLATAKALLDGLRDAGVLPVALAYGTSEIDLLSQQLGVPLLAKFRAQYEPTAVSP
CCCCCCHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHCCHHHHHHHHCCCCCCCCC
PPPPPPPARAEPAPPAARPAPGRMQRTAVRSGQQLYAENCDLTVLSTVGAGAEVIADGSI
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCHHHHHCCCCEEEEEECCCCCEEEECCCE
HIYGTLRGRALAGAQGNPDARIFCRDFHAELVAIAGHYKVLDDVPMDLRGKAVQVWLEQD
EEEEEECCEEEECCCCCCCCEEEEEEHHHEEEHHHCCEEEECCCCCCCCCCEEEEEEECC
QIKIAALD
CEEEEEEC
>Mature Secondary Structure 
ASVNVDFEQAGELKIGQVGIANLRVRTLDVPRLVQEMRERVSRAPKLFGRAAVILDFGG
CCCCCCHHHCCCEEECCCCEEEEEEEEECHHHHHHHHHHHHHHHHHHHCCEEEEEECCC
LSQVPDLATAKALLDGLRDAGVLPVALAYGTSEIDLLSQQLGVPLLAKFRAQYEPTAVSP
CCCCCCHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHCCHHHHHHHHCCCCCCCCC
PPPPPPPARAEPAPPAARPAPGRMQRTAVRSGQQLYAENCDLTVLSTVGAGAEVIADGSI
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCHHHHHCCCCEEEEEECCCCCEEEECCCE
HIYGTLRGRALAGAQGNPDARIFCRDFHAELVAIAGHYKVLDDVPMDLRGKAVQVWLEQD
EEEEEECCEEEECCCCCCCCEEEEEEHHHEEEHHHCCEEEECCCCCCCCCCEEEEEEECC
QIKIAALD
CEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]