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The map label for this gene is pdxA [H]

Identifier: 78046457

GI number: 78046457

Start: 1029196

End: 1030167

Strand: Reverse

Name: pdxA [H]

Synonym: XCV0901

Alternate gene names: 78046457

Gene position: 1030167-1029196 (Counterclockwise)

Preceding gene: 78046458

Following gene: 78046456

Centisome position: 19.89

GC content: 68.72

Gene sequence:

>972_bases
ATGATGGTCCCGTCGCTCGCGCTGGTGCCAGGCGAGCCGGCCGGAATCGGGCCGGAGCTATGCATCCGGCTTGCGCAGCA
GCCGCGCTCGGACGCGCATCTGATTGCCTACGCCGACCCAGACACCCTGCACAGCGCCGCAACGGCGCTGTCGTTGCCTG
TACGGCTGCTCGATCCCGACCAGCCGGCACGTGCGCCCGGCGACCTGCCGCTGCATCCCGTTCGCCAGGCCGTGACCACG
CGTTTGGGCGCACCCGACCCGGCCAATGCGGCAGCAGTGATCGCCGGCCTGCGCAGCGCCGCGGGTGACTGCCTCGCCGG
CCGCCTGCAGGGAATCGTCACTGGCCCGGTGCACAAGGCAGTGATCAACGCCGGCGGCATTGCTTACACCGGCACCACCG
AACTGCTGGCCGAACAAGCCGGTTGCCCGGTGGTGATGATGCTGGCCAACAGCATCGTGCGCGTCGCGCTGGTGACAACC
CATCTGCCGCTTCGCGCGGTGGCCGATGCGATCACCGCCGATGCGCTGCTGCAATGCCTGCGCATTACCCATGCAGCGAT
GCAGCGCGACTTCGGTCTGGAGCACCCGCGCATCGCCGTGCTCGGCCTCAACCCGCACGCCGGCGAAGACGGTCACCTGG
GCCGCGAGGAACTGGATATCGTCATTCCGGTGCTAGAGCAGCTGCGCGGCGAGGGCATGCAGCTGATCGGCCCGCTGCCG
GCGGACACCGCGTTCTTGCCGCAGAAACTGCGCGGCTTCGACGCGGTGGTGGCGATGTATCACGACCAGGGCCTGCCGGT
GCTCAAGTACAGCGGCTTTGAGCAGGCTGTAAATATCACCCTGGGCCTGCCCTACCCGCGCGTGGCGGTGGATCACGGTA
CTGCGCTGGAACTGGCCGGCCGCGGAATCGCAGACCCCTCCAGCCTGATGGCAGCCACTGCGTTGTGCGCGCGATTGGCG
GCGCGCCGCTAA

Upstream 100 bases:

>100_bases
GATGACAATGCCACTGCCGCTCCGGCCAAATCGGCAGACCCGGCAGCGCCCTCGCCGCCGCCGGCAAAGCCGACGCGCTG
AGACCGGGCAGCCGGATAGC

Downstream 100 bases:

>100_bases
CACCACGCGTGCTTGCTCGGCGCGGGCATGCCGCATGGCGCACGCCGCCGATCCGCCAGGCCAGGCGGGCACGCGAACGA
CACCGCGCGCAGGCGCGGCC

Product: 4-hydroxythreonine-4-phosphate dehydrogenase

Products: NA

Alternate protein names: 4-(phosphohydroxy)-L-threonine dehydrogenase [H]

Number of amino acids: Translated: 323; Mature: 323

Protein sequence:

>323_residues
MMVPSLALVPGEPAGIGPELCIRLAQQPRSDAHLIAYADPDTLHSAATALSLPVRLLDPDQPARAPGDLPLHPVRQAVTT
RLGAPDPANAAAVIAGLRSAAGDCLAGRLQGIVTGPVHKAVINAGGIAYTGTTELLAEQAGCPVVMMLANSIVRVALVTT
HLPLRAVADAITADALLQCLRITHAAMQRDFGLEHPRIAVLGLNPHAGEDGHLGREELDIVIPVLEQLRGEGMQLIGPLP
ADTAFLPQKLRGFDAVVAMYHDQGLPVLKYSGFEQAVNITLGLPYPRVAVDHGTALELAGRGIADPSSLMAATALCARLA
ARR

Sequences:

>Translated_323_residues
MMVPSLALVPGEPAGIGPELCIRLAQQPRSDAHLIAYADPDTLHSAATALSLPVRLLDPDQPARAPGDLPLHPVRQAVTT
RLGAPDPANAAAVIAGLRSAAGDCLAGRLQGIVTGPVHKAVINAGGIAYTGTTELLAEQAGCPVVMMLANSIVRVALVTT
HLPLRAVADAITADALLQCLRITHAAMQRDFGLEHPRIAVLGLNPHAGEDGHLGREELDIVIPVLEQLRGEGMQLIGPLP
ADTAFLPQKLRGFDAVVAMYHDQGLPVLKYSGFEQAVNITLGLPYPRVAVDHGTALELAGRGIADPSSLMAATALCARLA
ARR
>Mature_323_residues
MMVPSLALVPGEPAGIGPELCIRLAQQPRSDAHLIAYADPDTLHSAATALSLPVRLLDPDQPARAPGDLPLHPVRQAVTT
RLGAPDPANAAAVIAGLRSAAGDCLAGRLQGIVTGPVHKAVINAGGIAYTGTTELLAEQAGCPVVMMLANSIVRVALVTT
HLPLRAVADAITADALLQCLRITHAAMQRDFGLEHPRIAVLGLNPHAGEDGHLGREELDIVIPVLEQLRGEGMQLIGPLP
ADTAFLPQKLRGFDAVVAMYHDQGLPVLKYSGFEQAVNITLGLPYPRVAVDHGTALELAGRGIADPSSLMAATALCARLA
ARR

Specific function: Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) [H]

COG id: COG1995

COG function: function code H; Pyridoxal phosphate biosynthesis protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pdxA family [H]

Homologues:

Organism=Escherichia coli, GI1786237, Length=319, Percent_Identity=51.0971786833856, Blast_Score=289, Evalue=2e-79,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005255 [H]

Pfam domain/function: PF04166 PdxA [H]

EC number: =1.1.1.262 [H]

Molecular weight: Translated: 33675; Mature: 33675

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMVPSLALVPGEPAGIGPELCIRLAQQPRSDAHLIAYADPDTLHSAATALSLPVRLLDPD
CCCCCEEECCCCCCCCCHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHCCEEEECCC
QPARAPGDLPLHPVRQAVTTRLGAPDPANAAAVIAGLRSAAGDCLAGRLQGIVTGPVHKA
CCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEECHHHHH
VINAGGIAYTGTTELLAEQAGCPVVMMLANSIVRVALVTTHLPLRAVADAITADALLQCL
HHCCCCEEECCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
RITHAAMQRDFGLEHPRIAVLGLNPHAGEDGHLGREELDIVIPVLEQLRGEGMQLIGPLP
HHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEECCCC
ADTAFLPQKLRGFDAVVAMYHDQGLPVLKYSGFEQAVNITLGLPYPRVAVDHGTALELAG
CCHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEEEEECCCCCEEECCCCEEEECC
RGIADPSSLMAATALCARLAARR
CCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MMVPSLALVPGEPAGIGPELCIRLAQQPRSDAHLIAYADPDTLHSAATALSLPVRLLDPD
CCCCCEEECCCCCCCCCHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHCCEEEECCC
QPARAPGDLPLHPVRQAVTTRLGAPDPANAAAVIAGLRSAAGDCLAGRLQGIVTGPVHKA
CCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEECHHHHH
VINAGGIAYTGTTELLAEQAGCPVVMMLANSIVRVALVTTHLPLRAVADAITADALLQCL
HHCCCCEEECCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
RITHAAMQRDFGLEHPRIAVLGLNPHAGEDGHLGREELDIVIPVLEQLRGEGMQLIGPLP
HHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEECCCC
ADTAFLPQKLRGFDAVVAMYHDQGLPVLKYSGFEQAVNITLGLPYPRVAVDHGTALELAG
CCHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEEEEECCCCCEEECCCCEEEECC
RGIADPSSLMAATALCARLAARR
CCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]