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The map label for this gene is emrY [C]

Identifier: 78046253

GI number: 78046253

Start: 790018

End: 791670

Strand: Reverse

Name: emrY [C]

Synonym: XCV0697

Alternate gene names: 78046253

Gene position: 791670-790018 (Counterclockwise)

Preceding gene: 78046261

Following gene: 78046252

Centisome position: 15.29

GC content: 67.15

Gene sequence:

>1653_bases
GTGCGCGACAAGTACGTCCAGCGCGACTGGCAGCCCCACGAGCGGCCCACCCTGCCCGGGTCGGCCTCCACCCCCCTGCA
CCCTATCCGGCGGCGTATTCAGTACGGCCTGGTGGGCGCGGTGGTGGCGCTCACCGGAGGGCTGAGCAACGCCCTGGTCA
CCGCCAACCTGCCCTACCTGCAAGGCACGCTGGGCGCCTATGCCACCGAAATGGCGTGGCTGCCGGCCGCCTATGTGATG
ACCAACATGTCGGCGAACCTGCTGCTGGTGAAGTTTCGCCAGCAGTTCGGGTTGCGCCGGTTCACCGAAATCTTCCTGGC
GCTGTACGCGCTCATCGCCTTCGCGCACCTGTTCGTGCACAGCCTGAGCTCGGCGATCACCGTGCGTGCCGCGCATGGGC
TGGTGGGCGCGGCGCTCAGCTCGCTGGGTCTGTATTACGTGATCCAGGCGTTCCCGAGCAAATATCGGCTCAAGGCCGTG
GTGCTGGGCCTGGGCATGACCCAGCTGGCGTTGCCGCTGGCGCGGGTGTTTTCCACCGACCTGCTGGAATTTGGCGAGTG
GCAAGGCCTGTACCTGTTCGAGTGCGGGCTGGCGGTGTTCGCGCTGGCCTGCGTGCTGGCGCTCAAGTTACCGCCAAGCG
ACCGGTATCGCGTGTTCGAGCCGCTGGATTTCCTCACCTTCAGCCTGTTCGCCGCCGGCGCCGCCGGCCTGGCCGCGGTG
CTCTCGCTCGGGCGCCTGCTGTGGTGGACCAGCACGCCGTGGCTGGGCGTGGTGCTGGCCGCGTCCATCGTGCTGCTGTG
CACGGCGGCCTGGATCGAACACAACCGCCGTAATCCGATGATCAACACGCGCTGGCTGGCCAGTGCGGACATGTTGCGGC
TGGGGCTGGCGATCCTGTTGATCCGCCTGGTGCTGTCGGAACAAAGCACCGGCGCCATCGGCTTCTTCCAGACGCTGGGC
CTGGCCAACACGCAACTGCAGACCCTGTTTGCGCTGATGCTGCTGGGCGCGGTGGTCGGCGTGGCGGCCAGCGCGTGGCT
GATCAACCCGGCGCGGGTTGCCGAACATCTGATCATCGCGGTGGCGGCCATCTGTGTGGGCTGCTTCATGGATGCCGATG
CCACCAGCCTCACCCGCCCCGAACAGATGTATGTGAGCCAGTTCCTGCTCGCCTTCGGCAGCACGTTCTTCATCGGCCCG
GCGATGGTGGCCGGCATCGGCCGGGTGATCGCGCAGCCGGGCAACCTGATCAGTTTCATCGTGCTGTTCGGCATGGCGCA
GAACATGGGCGGCCTGCTCGGCAGCGCCCTGCTCGGCACCGTGCAGGTGGTGCGCGAGAAATACCATTCCAGCCAATTGG
TGGAACATCTGGCGCTGACCGACCCGCAGGTGGCCGCGCGCGTACAGGCCTATGCAAGCCTGTATGGCCGCAGCATCGGC
GACCCGGCACTGCGTCAGGCCCAAGGCGTGCGCACGCTGGGCACGGTCGCCACGCGCGAGGCCAATGTGCTGGCGTACAA
CGACGTGTTCCTGTTGATCGGCTGCATCGCCATCGCCACCGGCGTGTGGATCCTGTCCGTGCTGCTGTGGCGCCGCTATC
TGCGCCCCTCGGTATCGCCCCCTCCTCCTCCTGCTCCCACTGCGCGCCCATGA

Upstream 100 bases:

>100_bases
GGGATTCGCTCATGGCTGGATTATCGCACTGCTGACGCCGCCATGACCGCAACCGGACCACAATCGCGTTTTCACCTGCG
ACCGGCCCTGCGAGCACTCA

Downstream 100 bases:

>100_bases
AGACACCAGCAGATTCCTCCCCGCCTGCCGACCGGCAACGTCGTCGGCGTCGTCGTCTGGCCGGGGTCATCGGCTTCGGC
GGGCTTGCCCTGATCGGCGT

Product: major facilitator superfamily protein

Products: Proton [Cytoplasm]; multidrug [Periplasm] [C]

Alternate protein names: Facilitator Superfamily Protein; Transport Protein Transmembrane; Facilitator Superfamily Transporter; MFS Drug Efflux Transporter RmrB; EmrB/QacA Subfamily Drug Resistance Transporter; Transporter Facilitator Family; Multidrug Resistance Protein B; Transmembrane Efflux Pump Protein; Tat Pathway Signal Sequence Domain Protein; EmrB/QacA Family Drug Resistance Transporter; MFS Drug Efflux Transporter; MFS Permease; LOW QUALITY PROTEIN MFS Drug Efflux Transporter; Efflux Protein; Facilitator Superfamily Transporter Protein; MFS Family Transporter; HlyD Family Protein; Facilitator Family Transporter; Facilitator Superfamily Permease

Number of amino acids: Translated: 550; Mature: 550

Protein sequence:

>550_residues
MRDKYVQRDWQPHERPTLPGSASTPLHPIRRRIQYGLVGAVVALTGGLSNALVTANLPYLQGTLGAYATEMAWLPAAYVM
TNMSANLLLVKFRQQFGLRRFTEIFLALYALIAFAHLFVHSLSSAITVRAAHGLVGAALSSLGLYYVIQAFPSKYRLKAV
VLGLGMTQLALPLARVFSTDLLEFGEWQGLYLFECGLAVFALACVLALKLPPSDRYRVFEPLDFLTFSLFAAGAAGLAAV
LSLGRLLWWTSTPWLGVVLAASIVLLCTAAWIEHNRRNPMINTRWLASADMLRLGLAILLIRLVLSEQSTGAIGFFQTLG
LANTQLQTLFALMLLGAVVGVAASAWLINPARVAEHLIIAVAAICVGCFMDADATSLTRPEQMYVSQFLLAFGSTFFIGP
AMVAGIGRVIAQPGNLISFIVLFGMAQNMGGLLGSALLGTVQVVREKYHSSQLVEHLALTDPQVAARVQAYASLYGRSIG
DPALRQAQGVRTLGTVATREANVLAYNDVFLLIGCIAIATGVWILSVLLWRRYLRPSVSPPPPPAPTARP

Sequences:

>Translated_550_residues
MRDKYVQRDWQPHERPTLPGSASTPLHPIRRRIQYGLVGAVVALTGGLSNALVTANLPYLQGTLGAYATEMAWLPAAYVM
TNMSANLLLVKFRQQFGLRRFTEIFLALYALIAFAHLFVHSLSSAITVRAAHGLVGAALSSLGLYYVIQAFPSKYRLKAV
VLGLGMTQLALPLARVFSTDLLEFGEWQGLYLFECGLAVFALACVLALKLPPSDRYRVFEPLDFLTFSLFAAGAAGLAAV
LSLGRLLWWTSTPWLGVVLAASIVLLCTAAWIEHNRRNPMINTRWLASADMLRLGLAILLIRLVLSEQSTGAIGFFQTLG
LANTQLQTLFALMLLGAVVGVAASAWLINPARVAEHLIIAVAAICVGCFMDADATSLTRPEQMYVSQFLLAFGSTFFIGP
AMVAGIGRVIAQPGNLISFIVLFGMAQNMGGLLGSALLGTVQVVREKYHSSQLVEHLALTDPQVAARVQAYASLYGRSIG
DPALRQAQGVRTLGTVATREANVLAYNDVFLLIGCIAIATGVWILSVLLWRRYLRPSVSPPPPPAPTARP
>Mature_550_residues
MRDKYVQRDWQPHERPTLPGSASTPLHPIRRRIQYGLVGAVVALTGGLSNALVTANLPYLQGTLGAYATEMAWLPAAYVM
TNMSANLLLVKFRQQFGLRRFTEIFLALYALIAFAHLFVHSLSSAITVRAAHGLVGAALSSLGLYYVIQAFPSKYRLKAV
VLGLGMTQLALPLARVFSTDLLEFGEWQGLYLFECGLAVFALACVLALKLPPSDRYRVFEPLDFLTFSLFAAGAAGLAAV
LSLGRLLWWTSTPWLGVVLAASIVLLCTAAWIEHNRRNPMINTRWLASADMLRLGLAILLIRLVLSEQSTGAIGFFQTLG
LANTQLQTLFALMLLGAVVGVAASAWLINPARVAEHLIIAVAAICVGCFMDADATSLTRPEQMYVSQFLLAFGSTFFIGP
AMVAGIGRVIAQPGNLISFIVLFGMAQNMGGLLGSALLGTVQVVREKYHSSQLVEHLALTDPQVAARVQAYASLYGRSIG
DPALRQAQGVRTLGTVATREANVLAYNDVFLLIGCIAIATGVWILSVLLWRRYLRPSVSPPPPPAPTARP

Specific function: Unknown

COG id: COG0477

COG function: function code GEPR; Permeases of the major facilitator superfamily

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 59451; Mature: 59451

Theoretical pI: Translated: 9.90; Mature: 9.90

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCCCCCCC
>Mature Secondary Structure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CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; multidrug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + multidrug [Cytoplasm] = Proton [Cytoplasm] + multidrug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA