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The map label for this gene is emrK [H]

Identifier: 78046252

GI number: 78046252

Start: 788933

End: 790021

Strand: Reverse

Name: emrK [H]

Synonym: XCV0696

Alternate gene names: 78046252

Gene position: 790021-788933 (Counterclockwise)

Preceding gene: 78046253

Following gene: 78046251

Centisome position: 15.26

GC content: 66.76

Gene sequence:

>1089_bases
ATGAAGACACCAGCAGATTCCTCCCCGCCTGCCGACCGGCAACGTCGTCGGCGTCGTCGTCTGGCCGGGGTCATCGGCTT
CGGCGGGCTTGCCCTGATCGGCGTGGCGCTGGTGCTGTATGCCTGGCGCCTGCCGCCGTTCGTCAGTGCGATCGAACGCA
CCGAAAATGCGATGGTGCACGGTCAGATCACGGTGATTGCGCCGCAGGTGAGCGGCTATGTCACGCAGGTACCGGTGCAG
GACTTTGCGCACGTCAAGCGCGGCCAGTTGCTGGCACGCATCGACGATCGCATCTATGCCCAGCAACTCGAACAGGCCAA
GGCGCAAGTGCAGACCGCCCAGGCCAACCTTGCCAACTGGGATCAACAACGCCACAGCGCCGAAGCCACGATCGCCGAGC
AACGCGCGGCGCTGAGCAGCAACCAGGCACAACGCGAGCGCACCCATTCGGCCTATGCACGGACGCAGCAGCTGGCCAGC
CAGCAACTGGTCTCCGAGCAGGACCGCGACACCGCATTTGCCGCGCGCGCGCAAGCCGATGCCGGCGTGGCGCAGGCACG
TGCCGCAGTGCAGGCTGCCGAAGAAAACGCCCGCAGCGTGACCGTCAACCGCGCCGCGTTGGAAGCCGCGCTCGCCAATG
CACAGGCCACCGTGCAGCTGGCACAGATCAACCTGGACAACACGCGCATCCTGGCCCCGCGCGACGGCCAGCTCGGCCAG
CTTGGCGTGCGCCAGGGCGCCTACGTCACCAACGGCACGCAGCTGATGTCGCTGGTGCCGGACACGCTGTGGATCGTGGC
CAATTTCAAGGAAACCCAGATGGCCAGGATCCGCATCGGCCAGCGCGCCAGCTTCACCGTGGATGCGCTGGACAACGCGC
GTCTGCATGGCCGCGTACAGGACATTTCGCCGGCTGCCGGCTCCGAATTCAGCGTGCTGCCGGCCGATAACGCCACCGGC
AACTTCGTCAAGATTGCCCAACGCATTCCGCTGCGCATCAGCGTCGATCCGGACCAGCCGTTGGCGCCGCGGCTGCGGCC
GGGCATGTCGGTGGTGGTGGCCGTCGATACCGACAGCGCAGTCGACTAG

Upstream 100 bases:

>100_bases
CCATCGCCACCGGCGTGTGGATCCTGTCCGTGCTGCTGTGGCGCCGCTATCTGCGCCCCTCGGTATCGCCCCCTCCTCCT
CCTGCTCCCACTGCGCGCCC

Downstream 100 bases:

>100_bases
GCACAAACCGGTATCCGCGCGTGGGCACCAGTGTCGGCGCAGGTCAGGCAGCCAGTACCCCACACCGGCATGACGTCGCA
GCTCAACGGCGGCACTGCCG

Product: membrane fusion protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 362; Mature: 362

Protein sequence:

>362_residues
MKTPADSSPPADRQRRRRRRLAGVIGFGGLALIGVALVLYAWRLPPFVSAIERTENAMVHGQITVIAPQVSGYVTQVPVQ
DFAHVKRGQLLARIDDRIYAQQLEQAKAQVQTAQANLANWDQQRHSAEATIAEQRAALSSNQAQRERTHSAYARTQQLAS
QQLVSEQDRDTAFAARAQADAGVAQARAAVQAAEENARSVTVNRAALEAALANAQATVQLAQINLDNTRILAPRDGQLGQ
LGVRQGAYVTNGTQLMSLVPDTLWIVANFKETQMARIRIGQRASFTVDALDNARLHGRVQDISPAAGSEFSVLPADNATG
NFVKIAQRIPLRISVDPDQPLAPRLRPGMSVVVAVDTDSAVD

Sequences:

>Translated_362_residues
MKTPADSSPPADRQRRRRRRLAGVIGFGGLALIGVALVLYAWRLPPFVSAIERTENAMVHGQITVIAPQVSGYVTQVPVQ
DFAHVKRGQLLARIDDRIYAQQLEQAKAQVQTAQANLANWDQQRHSAEATIAEQRAALSSNQAQRERTHSAYARTQQLAS
QQLVSEQDRDTAFAARAQADAGVAQARAAVQAAEENARSVTVNRAALEAALANAQATVQLAQINLDNTRILAPRDGQLGQ
LGVRQGAYVTNGTQLMSLVPDTLWIVANFKETQMARIRIGQRASFTVDALDNARLHGRVQDISPAAGSEFSVLPADNATG
NFVKIAQRIPLRISVDPDQPLAPRLRPGMSVVVAVDTDSAVD
>Mature_362_residues
MKTPADSSPPADRQRRRRRRLAGVIGFGGLALIGVALVLYAWRLPPFVSAIERTENAMVHGQITVIAPQVSGYVTQVPVQ
DFAHVKRGQLLARIDDRIYAQQLEQAKAQVQTAQANLANWDQQRHSAEATIAEQRAALSSNQAQRERTHSAYARTQQLAS
QQLVSEQDRDTAFAARAQADAGVAQARAAVQAAEENARSVTVNRAALEAALANAQATVQLAQINLDNTRILAPRDGQLGQ
LGVRQGAYVTNGTQLMSLVPDTLWIVANFKETQMARIRIGQRASFTVDALDNARLHGRVQDISPAAGSEFSVLPADNATG
NFVKIAQRIPLRISVDPDQPLAPRLRPGMSVVVAVDTDSAVD

Specific function: Unknown

COG id: COG1566

COG function: function code V; Multidrug resistance efflux pump

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1788711, Length=351, Percent_Identity=33.6182336182336, Blast_Score=152, Evalue=2e-38,
Organism=Escherichia coli, GI1789041, Length=355, Percent_Identity=32.6760563380282, Blast_Score=149, Evalue=3e-37,
Organism=Escherichia coli, GI1790519, Length=322, Percent_Identity=28.2608695652174, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI87081951, Length=337, Percent_Identity=26.7062314540059, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI1789637, Length=316, Percent_Identity=25.9493670886076, Blast_Score=85, Evalue=9e-18,
Organism=Escherichia coli, GI87081796, Length=307, Percent_Identity=27.3615635179153, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1790024, Length=284, Percent_Identity=26.4084507042254, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1790012, Length=246, Percent_Identity=26.4227642276423, Blast_Score=68, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005694
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 39166; Mature: 39166

Theoretical pI: Translated: 10.40; Mature: 10.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTPADSSPPADRQRRRRRRLAGVIGFGGLALIGVALVLYAWRLPPFVSAIERTENAMVH
CCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCEEE
GQITVIAPQVSGYVTQVPVQDFAHVKRGQLLARIDDRIYAQQLEQAKAQVQTAQANLANW
EEEEEEEECCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DQQRHSAEATIAEQRAALSSNQAQRERTHSAYARTQQLASQQLVSEQDRDTAFAARAQAD
HHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
AGVAQARAAVQAAEENARSVTVNRAALEAALANAQATVQLAQINLDNTRILAPRDGQLGQ
HHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHCCHHEEEEEEEECCCCEEECCCCCCCCC
LGVRQGAYVTNGTQLMSLVPDTLWIVANFKETQMARIRIGQRASFTVDALDNARLHGRVQ
HHCCCCCEEECCHHHHHHCCCEEEEEECCCHHHHHHHCCCCCCCEEEECCCCCHHCCEEE
DISPAAGSEFSVLPADNATGNFVKIAQRIPLRISVDPDQPLAPRLRPGMSVVVAVDTDSA
CCCCCCCCCEEEEECCCCCCCHHHHHHHCCEEEEECCCCCCCCCCCCCCEEEEEECCCCC
VD
CC
>Mature Secondary Structure
MKTPADSSPPADRQRRRRRRLAGVIGFGGLALIGVALVLYAWRLPPFVSAIERTENAMVH
CCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCEEE
GQITVIAPQVSGYVTQVPVQDFAHVKRGQLLARIDDRIYAQQLEQAKAQVQTAQANLANW
EEEEEEEECCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DQQRHSAEATIAEQRAALSSNQAQRERTHSAYARTQQLASQQLVSEQDRDTAFAARAQAD
HHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
AGVAQARAAVQAAEENARSVTVNRAALEAALANAQATVQLAQINLDNTRILAPRDGQLGQ
HHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHCCHHEEEEEEEECCCCEEECCCCCCCCC
LGVRQGAYVTNGTQLMSLVPDTLWIVANFKETQMARIRIGQRASFTVDALDNARLHGRVQ
HHCCCCCEEECCHHHHHHCCCEEEEEECCCHHHHHHHCCCCCCCEEEECCCCCHHCCEEE
DISPAAGSEFSVLPADNATGNFVKIAQRIPLRISVDPDQPLAPRLRPGMSVVVAVDTDSA
CCCCCCCCCEEEEECCCCCCCHHHHHHHCCEEEEECCCCCCCCCCCCCCEEEEEECCCCC
VD
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]