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The map label for this gene is aspC [C]

Identifier: 78046242

GI number: 78046242

Start: 778351

End: 779535

Strand: Reverse

Name: aspC [C]

Synonym: XCV0686

Alternate gene names: 78046242

Gene position: 779535-778351 (Counterclockwise)

Preceding gene: 78046250

Following gene: 78046239

Centisome position: 15.05

GC content: 65.06

Gene sequence:

>1185_bases
ATGGATTCCACACTTCCGTACGCAGGCGGCTATAGCCGTCGCAGCCAGGACATCGCCCCGTTTCATGTCATGTCGCTGCT
GGCGCGCGCCAATGCGCTCGAGCAGGCCGGCCACGACGTGATCCACCTGGAAATCGGCGAGCCCGACTTCACCACTGCCG
CGCCGATCGTCGCTGCCGGCCAGGCGGCATTGGCAGCCGGCCACACCCGCTACACCGCCGCACGCGGGCTGCCGGCGCTG
CGCGAGGCGATTGCCGGCTTCTATGCGCAACGCTACGCCTGCAACCTCGATCCGGAGCGGATTCTGGTGACACCCGGGGG
GTCTGGCGCATTGCTGCTGGCCAGCAGCCTGCTGGTGGATCCGGGCAAGCATTGGTTGCTCGCCGACCCGGGCTACCCGT
GCAACCGGCATTTTCTGCGCCTGGTCGAAGGCGCCGCGCAATTGGTCCCGGTCGGCCCGGACAGCGATTATCAGTTGACC
CCTGCGCTGGTGGAGAGCGCCTGGAACGCCGACAGCGTGGGCGCCCTGGTGGCCTCACCGGCAAATCCCACCGGCAGCGT
GCTGTCGCGCACGCAACTGGCTGCGCTTTCGCAGGCGCTGCATGCGCGCGGTGGCCATCTGGTGGTCGACGAGATCTATC
ACGGCCTGACCTACGGCCTGGACGCGCACAGCGTGCTGGAGGTGGACGATGGCGCGTTCGTGCTGAACAGTTTTTCCAAG
TACTTCGGCATGACCGGCTGGCGGCTGGGCTGGCTGATCGCACCGCCCGACGCGGTGCCGGAATTGGAAAAGCTTGCGCA
GAATCTCTACATCAGTGCCTCGACAATTGCCCAGCACGCCGCACTGGCCTGCTTCACGCCCGAGAGCATCGCCATCTTCG
AAGCGCGCCGCGGTGAGTTTCAGCAGCGTCGCGATTACCTGCTGCCGGCCTTGCGTGCGCTGGGCTTCGAGATCGCAGTC
GAACCGCAAGGCGCGTTTTACTTGTATGCCGACATCAGCGGATTTTCAGATGATGCGCAGGCGTTTTGCGCGCATTTTCT
GGAAACCGAACATGTTGCGTTTACGCCCGGCATCGACTTCGGCCACTACCGCGCCAACCAGCACGTCCGCATTGCCTACA
CGCAAAGCCTGCCGCGTCTGCAGCAGGCGGTGGAGCGGATTGCGCGTGGGTTGAAGCGGTTGTAG

Upstream 100 bases:

>100_bases
GTCCATTGGATGAACGCAATGCCATCCCGGCACCGGAGTGTGGAAGAGCCCCTTGTCGGGCGCCATGTGTCCTGGGTCAT
GCTGGTCTATCATCGAGCCA

Downstream 100 bases:

>100_bases
CAGGCTGCGTGACCCGCAGTGCGCTGCACGGACGTTTTGCGTAAGGCGCCGACGCCTTGCGCATTGCGTAGCACGCGCGT
TCTCCACTGCGCACCCGCTG

Product: hypothetical protein

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 394; Mature: 394

Protein sequence:

>394_residues
MDSTLPYAGGYSRRSQDIAPFHVMSLLARANALEQAGHDVIHLEIGEPDFTTAAPIVAAGQAALAAGHTRYTAARGLPAL
REAIAGFYAQRYACNLDPERILVTPGGSGALLLASSLLVDPGKHWLLADPGYPCNRHFLRLVEGAAQLVPVGPDSDYQLT
PALVESAWNADSVGALVASPANPTGSVLSRTQLAALSQALHARGGHLVVDEIYHGLTYGLDAHSVLEVDDGAFVLNSFSK
YFGMTGWRLGWLIAPPDAVPELEKLAQNLYISASTIAQHAALACFTPESIAIFEARRGEFQQRRDYLLPALRALGFEIAV
EPQGAFYLYADISGFSDDAQAFCAHFLETEHVAFTPGIDFGHYRANQHVRIAYTQSLPRLQQAVERIARGLKRL

Sequences:

>Translated_394_residues
MDSTLPYAGGYSRRSQDIAPFHVMSLLARANALEQAGHDVIHLEIGEPDFTTAAPIVAAGQAALAAGHTRYTAARGLPAL
REAIAGFYAQRYACNLDPERILVTPGGSGALLLASSLLVDPGKHWLLADPGYPCNRHFLRLVEGAAQLVPVGPDSDYQLT
PALVESAWNADSVGALVASPANPTGSVLSRTQLAALSQALHARGGHLVVDEIYHGLTYGLDAHSVLEVDDGAFVLNSFSK
YFGMTGWRLGWLIAPPDAVPELEKLAQNLYISASTIAQHAALACFTPESIAIFEARRGEFQQRRDYLLPALRALGFEIAV
EPQGAFYLYADISGFSDDAQAFCAHFLETEHVAFTPGIDFGHYRANQHVRIAYTQSLPRLQQAVERIARGLKRL
>Mature_394_residues
MDSTLPYAGGYSRRSQDIAPFHVMSLLARANALEQAGHDVIHLEIGEPDFTTAAPIVAAGQAALAAGHTRYTAARGLPAL
REAIAGFYAQRYACNLDPERILVTPGGSGALLLASSLLVDPGKHWLLADPGYPCNRHFLRLVEGAAQLVPVGPDSDYQLT
PALVESAWNADSVGALVASPANPTGSVLSRTQLAALSQALHARGGHLVVDEIYHGLTYGLDAHSVLEVDDGAFVLNSFSK
YFGMTGWRLGWLIAPPDAVPELEKLAQNLYISASTIAQHAALACFTPESIAIFEARRGEFQQRRDYLLPALRALGFEIAV
EPQGAFYLYADISGFSDDAQAFCAHFLETEHVAFTPGIDFGHYRANQHVRIAYTQSLPRLQQAVERIARGLKRL

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=324, Percent_Identity=28.0864197530864, Blast_Score=131, Evalue=9e-31,
Organism=Homo sapiens, GI169881279, Length=324, Percent_Identity=28.0864197530864, Blast_Score=131, Evalue=9e-31,
Organism=Homo sapiens, GI56713256, Length=326, Percent_Identity=26.3803680981595, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI56713254, Length=326, Percent_Identity=26.3803680981595, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI169881281, Length=212, Percent_Identity=25.9433962264151, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI4507369, Length=402, Percent_Identity=23.3830845771144, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI149944424, Length=206, Percent_Identity=29.6116504854369, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI1788722, Length=390, Percent_Identity=27.4358974358974, Blast_Score=114, Evalue=8e-27,
Organism=Escherichia coli, GI1786816, Length=374, Percent_Identity=28.6096256684492, Blast_Score=108, Evalue=5e-25,
Organism=Escherichia coli, GI1788627, Length=386, Percent_Identity=26.6839378238342, Blast_Score=93, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI71994476, Length=379, Percent_Identity=25.3298153034301, Blast_Score=96, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI71994472, Length=379, Percent_Identity=25.3298153034301, Blast_Score=96, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17567663, Length=373, Percent_Identity=24.3967828418231, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17567369, Length=304, Percent_Identity=23.3552631578947, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6322401, Length=389, Percent_Identity=22.3650385604113, Blast_Score=82, Evalue=1e-16,
Organism=Drosophila melanogaster, GI28573069, Length=285, Percent_Identity=26.6666666666667, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24646114, Length=285, Percent_Identity=26.6666666666667, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI28573067, Length=285, Percent_Identity=26.6666666666667, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI28573065, Length=285, Percent_Identity=26.6666666666667, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI18859735, Length=376, Percent_Identity=24.2021276595745, Blast_Score=84, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 42527; Mature: 42527

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSTLPYAGGYSRRSQDIAPFHVMSLLARANALEQAGHDVIHLEIGEPDFTTAAPIVAAG
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHCC
QAALAAGHTRYTAARGLPALREAIAGFYAQRYACNLDPERILVTPGGSGALLLASSLLVD
CHHHHCCCHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHCC
PGKHWLLADPGYPCNRHFLRLVEGAAQLVPVGPDSDYQLTPALVESAWNADSVGALVASP
CCCCEEEECCCCCHHHHHHHHHHCHHHEEECCCCCCCEECHHHHHCCCCCCCCCCEEECC
ANPTGSVLSRTQLAALSQALHARGGHLVVDEIYHGLTYGLDAHSVLEVDDGAFVLNSFSK
CCCCHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHH
YFGMTGWRLGWLIAPPDAVPELEKLAQNLYISASTIAQHAALACFTPESIAIFEARRGEF
HHCCCCCEEEEEECCCCCCHHHHHHHHHHEECHHHHHHHHEEEEECCCCEEEEEHHCCHH
QQRRDYLLPALRALGFEIAVEPQGAFYLYADISGFSDDAQAFCAHFLETEHVAFTPGIDF
HHHHHHHHHHHHHCCCEEEECCCCCEEEEEECCCCCHHHHHHHHHHHCCCCEEECCCCCC
GHYRANQHVRIAYTQSLPRLQQAVERIARGLKRL
CCCCCCCEEEEEEHHCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDSTLPYAGGYSRRSQDIAPFHVMSLLARANALEQAGHDVIHLEIGEPDFTTAAPIVAAG
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHCC
QAALAAGHTRYTAARGLPALREAIAGFYAQRYACNLDPERILVTPGGSGALLLASSLLVD
CHHHHCCCHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHCC
PGKHWLLADPGYPCNRHFLRLVEGAAQLVPVGPDSDYQLTPALVESAWNADSVGALVASP
CCCCEEEECCCCCHHHHHHHHHHCHHHEEECCCCCCCEECHHHHHCCCCCCCCCCEEECC
ANPTGSVLSRTQLAALSQALHARGGHLVVDEIYHGLTYGLDAHSVLEVDDGAFVLNSFSK
CCCCHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHH
YFGMTGWRLGWLIAPPDAVPELEKLAQNLYISASTIAQHAALACFTPESIAIFEARRGEF
HHCCCCCEEEEEECCCCCCHHHHHHHHHHEECHHHHHHHHEEEEECCCCEEEEEHHCCHH
QQRRDYLLPALRALGFEIAVEPQGAFYLYADISGFSDDAQAFCAHFLETEHVAFTPGIDF
HHHHHHHHHHHHHCCCEEEECCCCCEEEEEECCCCCHHHHHHHHHHHCCCCEEECCCCCC
GHYRANQHVRIAYTQSLPRLQQAVERIARGLKRL
CCCCCCCEEEEEEHHCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]