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The map label for this gene is tadA [H]

Identifier: 78046250

GI number: 78046250

Start: 787867

End: 788322

Strand: Reverse

Name: tadA [H]

Synonym: XCV0694

Alternate gene names: 78046250

Gene position: 788322-787867 (Counterclockwise)

Preceding gene: 78046251

Following gene: 78046242

Centisome position: 15.22

GC content: 63.16

Gene sequence:

>456_bases
ATGATCACCACCCCCGACTACCGCGCATTGCTGGACACCGCCATTACCGAAGCACGCCAGGGCCTGGCCGAAGGCGGCAT
CCCGATTGGCGCAGCGCTGTACCACAACGACGGGCGCCTGCTCGGCTGCGGCCATAACCGCCGCGTGCAGGAAAACGACC
CCTCGGTACACGGCGAGACCGACGCATTTCGCAAGGCCGGCCGCCAGCGCCGCTACAAGGACACAATCATGGTCACCACG
TTGGCGCCGTGCTGGTACTGCAGCGGGCTGGTACGCCAGTTCAACATCGGCACGGTGGTGGTGGGCGAATCGGTCACGTT
CCAGGGCGGCATCGCATGGTTGCGCGAGCACGGCGTCAACGTGATCGATCTGCATAGCCAGGAATGCATCGACCTGCTTG
GCGGCTATATTTCCGCCAACCCGGATGTGTGGAACGAAGATATTGGCGAGGATTGA

Upstream 100 bases:

>100_bases
CGGCGCACGGGTTTGCACCTGCTTCCGCACCGTACCTGGAAGATGGCATTCCACATCTCGACCTGCTGCGCCCCGCCGGC
GCGGCCCCTTTGGAGTTCGC

Downstream 100 bases:

>100_bases
GGTCAGCGCCACTGCAGGTGCGTAGCCGTGCGCGGTGACAGATGACAGGCAATGCCACTGCGCAGTGGCGCTGCTGTTTG
GCTTGCATCGCAGTGCCAAT

Product: putative cytosine deaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 151; Mature: 151

Protein sequence:

>151_residues
MITTPDYRALLDTAITEARQGLAEGGIPIGAALYHNDGRLLGCGHNRRVQENDPSVHGETDAFRKAGRQRRYKDTIMVTT
LAPCWYCSGLVRQFNIGTVVVGESVTFQGGIAWLREHGVNVIDLHSQECIDLLGGYISANPDVWNEDIGED

Sequences:

>Translated_151_residues
MITTPDYRALLDTAITEARQGLAEGGIPIGAALYHNDGRLLGCGHNRRVQENDPSVHGETDAFRKAGRQRRYKDTIMVTT
LAPCWYCSGLVRQFNIGTVVVGESVTFQGGIAWLREHGVNVIDLHSQECIDLLGGYISANPDVWNEDIGED
>Mature_151_residues
MITTPDYRALLDTAITEARQGLAEGGIPIGAALYHNDGRLLGCGHNRRVQENDPSVHGETDAFRKAGRQRRYKDTIMVTT
LAPCWYCSGLVRQFNIGTVVVGESVTFQGGIAWLREHGVNVIDLHSQECIDLLGGYISANPDVWNEDIGED

Specific function: Deaminates adenosine-34 to inosine in tRNA-Arg2 [H]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Escherichia coli, GI145693172, Length=136, Percent_Identity=31.6176470588235, Blast_Score=63, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6325319, Length=144, Percent_Identity=40.2777777777778, Blast_Score=106, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: NA

Molecular weight: Translated: 16599; Mature: 16599

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITTPDYRALLDTAITEARQGLAEGGIPIGAALYHNDGRLLGCGHNRRVQENDPSVHGET
CCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCEEECCCCCCCCCCCCCCCCCH
DAFRKAGRQRRYKDTIMVTTLAPCWYCSGLVRQFNIGTVVVGESVTFQGGIAWLREHGVN
HHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHCCCCEEEECCCEEEHHHHHHHHHCCCC
VIDLHSQECIDLLGGYISANPDVWNEDIGED
EEEECHHHHHHHHCCHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MITTPDYRALLDTAITEARQGLAEGGIPIGAALYHNDGRLLGCGHNRRVQENDPSVHGET
CCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCEEECCCCCCCCCCCCCCCCCH
DAFRKAGRQRRYKDTIMVTTLAPCWYCSGLVRQFNIGTVVVGESVTFQGGIAWLREHGVN
HHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHCCCCEEEECCCEEEHHHHHHHHHCCCC
VIDLHSQECIDLLGGYISANPDVWNEDIGED
EEEECHHHHHHHHCCHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]