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The map label for this gene is glpR [H]

Identifier: 78045931

GI number: 78045931

Start: 428514

End: 429476

Strand: Reverse

Name: glpR [H]

Synonym: XCV0375

Alternate gene names: 78045931

Gene position: 429476-428514 (Counterclockwise)

Preceding gene: 78045932

Following gene: 78045930

Centisome position: 8.29

GC content: 66.87

Gene sequence:

>963_bases
ATGCCTCCAGAACCGTGCAGCCTCAGCGCAGCGCGTCCGGCATGTCGCCACGCGTGCACCGCTTCAGGCCGATGTTCGCC
GGCAAGCCCCTGTCGCGCTCAGCGTGCACCCCGCCGTGTTTGCATCCTCACGCGTATGCGCGATCATCTGCGCATGGAGT
CGACTCACTACAGGACGGTCCCGGCGCCGGCGTTGAACCCGCGCCAGGAGCAATTGGTGGCGCTGGTGCGGCAGCAGGGC
TTTGCCGAGGTCGAAGGTTTGGCCACACGCTTCGAGGTGACGCCGCAGACCATCCGCCGCGATCTGACCTTGCTCTGCGA
TGCAGGCGTGCTGCGCCGCTATCACGGCGGCGTCAGCATGCCCTCCAGCGTGGAGAATCTGGCCTACACCGCACGCAAAG
CGCTGCAGGCCCGCGAAAAGCAGCACATCGCCGCACGTGTGGCGCGTTTCATTCCCGACGATGCCTCGCTGTTCATCAAC
CTGGGGACCACCAACGAAGAAGTCGCACGCGCGTTGCTGCAGCACCGCGGGCTGCGCGTGATCACCAATAACCTCAACGT
GGCGGTGATGCTCAGCGCCAACCCCAGTTTCGAGGTGATCGTGGCCGGCGGTGTGGTGCGCGGGCGCGACCAAGGCGTGA
CCGGCGAGGCGACGGTGGAGCTGATCCGCCAGTTCAAGGTGGACTTCGGGGTGATCGGCATTTCCGGTATCGATCTGGAC
GGCACCCTGCTGGATTTCGATTACCAGGAAGTGCGCGTGGCGCAGGCCATCATCGAGCACTCGCGGCACGTGCTGCTGGC
CGCCGATCACAGCAAGTTCGGTCGCAACGCCATGGTGCGGCTGGGCGCCCTCGCCCAGGTGCACGACTGGTTCACCGACC
GGCCGCCGCCGCAGGAGTTGGCGAGCGTCCTGGCCGAGGCCGGTACCCGGGTGCACCTGGCGGACGCGGACGGAACCGCC
TGA

Upstream 100 bases:

>100_bases
GTCCGCGCGTTGCTGGCCACCTGCTCGTTGGCGCTTCAGCACGCACACACCGAAGGCGGCGATCTTTACCGAGCCCTGGC
CGAGCCTGCCGGGTAATCGT

Downstream 100 bases:

>100_bases
GTTCGATGTTCGTTTTTGAGCGTTTTTACGTGATAGCCGCCGAAAACCATTGGGCCTGATAGGTACGCCATCTCTTAATC
CGCTCTTTCATAGCCGATTC

Product: DeoR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 320; Mature: 319

Protein sequence:

>320_residues
MPPEPCSLSAARPACRHACTASGRCSPASPCRAQRAPRRVCILTRMRDHLRMESTHYRTVPAPALNPRQEQLVALVRQQG
FAEVEGLATRFEVTPQTIRRDLTLLCDAGVLRRYHGGVSMPSSVENLAYTARKALQAREKQHIAARVARFIPDDASLFIN
LGTTNEEVARALLQHRGLRVITNNLNVAVMLSANPSFEVIVAGGVVRGRDQGVTGEATVELIRQFKVDFGVIGISGIDLD
GTLLDFDYQEVRVAQAIIEHSRHVLLAADHSKFGRNAMVRLGALAQVHDWFTDRPPPQELASVLAEAGTRVHLADADGTA

Sequences:

>Translated_320_residues
MPPEPCSLSAARPACRHACTASGRCSPASPCRAQRAPRRVCILTRMRDHLRMESTHYRTVPAPALNPRQEQLVALVRQQG
FAEVEGLATRFEVTPQTIRRDLTLLCDAGVLRRYHGGVSMPSSVENLAYTARKALQAREKQHIAARVARFIPDDASLFIN
LGTTNEEVARALLQHRGLRVITNNLNVAVMLSANPSFEVIVAGGVVRGRDQGVTGEATVELIRQFKVDFGVIGISGIDLD
GTLLDFDYQEVRVAQAIIEHSRHVLLAADHSKFGRNAMVRLGALAQVHDWFTDRPPPQELASVLAEAGTRVHLADADGTA
>Mature_319_residues
PPEPCSLSAARPACRHACTASGRCSPASPCRAQRAPRRVCILTRMRDHLRMESTHYRTVPAPALNPRQEQLVALVRQQGF
AEVEGLATRFEVTPQTIRRDLTLLCDAGVLRRYHGGVSMPSSVENLAYTARKALQAREKQHIAARVARFIPDDASLFINL
GTTNEEVARALLQHRGLRVITNNLNVAVMLSANPSFEVIVAGGVVRGRDQGVTGEATVELIRQFKVDFGVIGISGIDLDG
TLLDFDYQEVRVAQAIIEHSRHVLLAADHSKFGRNAMVRLGALAQVHDWFTDRPPPQELASVLAEAGTRVHLADADGTA

Specific function: Repressor of the glycerol-3-phosphate regulon [H]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789829, Length=246, Percent_Identity=51.6260162601626, Blast_Score=267, Evalue=5e-73,
Organism=Escherichia coli, GI87082344, Length=252, Percent_Identity=41.6666666666667, Blast_Score=215, Evalue=3e-57,
Organism=Escherichia coli, GI1788069, Length=232, Percent_Identity=30.6034482758621, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1789059, Length=250, Percent_Identity=29.2, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1789519, Length=256, Percent_Identity=26.5625, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1790753, Length=250, Percent_Identity=27.2, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI226510968, Length=240, Percent_Identity=26.6666666666667, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1787540, Length=253, Percent_Identity=27.6679841897233, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1789170, Length=232, Percent_Identity=24.1379310344828, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 34986; Mature: 34854

Theoretical pI: Translated: 8.71; Mature: 8.71

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPEPCSLSAARPACRHACTASGRCSPASPCRAQRAPRRVCILTRMRDHLRMESTHYRTV
CCCCCCCCCCCCHHHHHHHCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHCCCCCEEC
PAPALNPRQEQLVALVRQQGFAEVEGLATRFEVTPQTIRRDLTLLCDAGVLRRYHGGVSM
CCCCCCCHHHHHHHHHHHCCHHHHHHHHHHEECCHHHHHHHHHHHHCHHHHHHHCCCCCC
PSSVENLAYTARKALQAREKQHIAARVARFIPDDASLFINLGTTNEEVARALLQHRGLRV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHCCCEE
ITNNLNVAVMLSANPSFEVIVAGGVVRGRDQGVTGEATVELIRQFKVDFGVIGISGIDLD
EECCCCEEEEEECCCCEEEEEECCEEECCCCCCCHHHHHHHHHHHHHCEEEEEEECCCCC
GTLLDFDYQEVRVAQAIIEHSRHVLLAADHSKFGRNAMVRLGALAQVHDWFTDRPPPQEL
CEEECCCHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHH
ASVLAEAGTRVHLADADGTA
HHHHHHCCCEEEEECCCCCC
>Mature Secondary Structure 
PPEPCSLSAARPACRHACTASGRCSPASPCRAQRAPRRVCILTRMRDHLRMESTHYRTV
CCCCCCCCCCCHHHHHHHCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHCCCCCEEC
PAPALNPRQEQLVALVRQQGFAEVEGLATRFEVTPQTIRRDLTLLCDAGVLRRYHGGVSM
CCCCCCCHHHHHHHHHHHCCHHHHHHHHHHEECCHHHHHHHHHHHHCHHHHHHHCCCCCC
PSSVENLAYTARKALQAREKQHIAARVARFIPDDASLFINLGTTNEEVARALLQHRGLRV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHCCCEE
ITNNLNVAVMLSANPSFEVIVAGGVVRGRDQGVTGEATVELIRQFKVDFGVIGISGIDLD
EECCCCEEEEEECCCCEEEEEECCEEECCCCCCCHHHHHHHHHHHHHCEEEEEEECCCCC
GTLLDFDYQEVRVAQAIIEHSRHVLLAADHSKFGRNAMVRLGALAQVHDWFTDRPPPQEL
CEEECCCHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHH
ASVLAEAGTRVHLADADGTA
HHHHHHCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8752340; 10984043 [H]