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The map label for this gene is glpD [H]

Identifier: 78045930

GI number: 78045930

Start: 426776

End: 428290

Strand: Reverse

Name: glpD [H]

Synonym: XCV0374

Alternate gene names: 78045930

Gene position: 428290-426776 (Counterclockwise)

Preceding gene: 78045931

Following gene: 78045929

Centisome position: 8.27

GC content: 67.66

Gene sequence:

>1515_bases
ATGGGCGAGATGTACGATCTTCTGGTAATCGGCGGCGGCATCAACGGGGTCGGCATTGCCCGTGATGCGGCCGGGCGCGG
TCTGTCGGTGTGCCTGTGCGAGCAGGACGACCTGGCCGCGCATACCAGCAGCGCCAGTACCAAACTCATTCACGGCGGCC
TGCGCTATCTGGAGCAGTACGAATTCGCGCTGGTCGGCAAGGCACTGGCCGAGCGCGAAGTGTTGCTGCGGCTGGCCCCG
CACATCATCTGGCCGTTGCGCTTCCTGCTGCCCCACCAACCGCACCTGCGCCCGGCATGGATGATCCGCGCCGGGCTGTT
CCTGTACGACCATCTGGGCGGCAGCAAGCGCAGCCTGCCGCGCTCGCGGCGGCTGTCGCTGCGGACGCACCCGGTCGGTG
CGCCGCTGCAGGAATCGCTGCGCACCGGCTTCGTGTATTCGGACGCCTGGGTGCAGGACGCGCGGCTGGTGGTGCTCAAC
GCGATGGACGCCGCCAGGCGCGGCGCCAAGATCCACACGCGCACGCGCTGTGTCGGCGCCTGGCACGATGCCGGCTTCTG
GTATGCCGAGCTCGAAGACCGCGAGGGCCGCCGCCGCACGGTGCAGGCGCGCGCGCTCGCCAATGCGGCCGGCCCCTGGG
CAGTGGCGTTCCTGGACACCGTGGCCTCGGTGCCGCACGAACACGCATTGCGGCTGGTCAAGGGCAGCCATATCGTGGTG
CCCAAGCTGTTCGATCACGACCATGCGTACATCTTCCAGCAACCGGACCGGCGCATCGTGTTCGCCATCCCCTACGAGCA
CGACTTCACCTTGATCGGCACCACCGACGTGGACTACGAAGCCGACCCCGCCGCGCCGAAGATCGATGCTGCCGAGGTGC
AGTACCTGTGCGATGCGGTGAACCTGTATTTCCAGCAGCAGATCTCCCCCGCCGATGTGGTGTGGAACTACAGCGGCGTG
CGCCCGTTGCTGGACGACGCCGAAGACAACGCAGCCGAAGTGACCCGCGATTACCAGCTGGAAGTGGTCACCGAGGGTGC
GCCGTTGCTCAACGTGTTCGGCGGCAAGCTGACCACCTATCGCAAGCTCGCCGAAGAGGCAGTGGACCGGCTCACCCACG
CGCTGGGCGCACGCAAGCCGGCGTGGACCGCACGTGGGGAGGCATTACCAGGCGGCGAGCAGCGCGATATCGCCAGCCTG
CTGGAACGCGTCGGCCGCGGTCGCCCCTGGCTGCCGGCGGCGACCGCGCAGCGGCTGGTGCGCAACTACGGCACCTGCGC
CGAACAACTGCTTGGCGATGCGCAGAGCCTGGCCGATCTGGGCACGCACTTCGGTGCGGACCTGTACCAGGCCGAGGTGG
ATTACCTGCGTCAACATGAATGGGCGGTGGCTGCCGACGATATCCTGTGGCGGCGCAGCAAGCTCGGCCTGCGGATCGAT
GCGGCCGGGCGGCAGCGCCTGGAAGACTATCTGCAGACGCAGTCGATCCGGCAACGCGATGCCGTTTCTGCTTGA

Upstream 100 bases:

>100_bases
AAAGCTGTCCATCTTCACGCCCCCGCAAGGTTCGATGTTCGAGTATGTTCGAACATGACAACTTGGGTTCGCTCATCAGC
GCGCCCGGACGGAGGCACCG

Downstream 100 bases:

>100_bases
ACACACCGCGTTGCCGGCGAGGACGGGTCGCCCGGCAACGTATTCCGGCGCTTCAGCCAGCGTCACCCAAGTCACGTGGA
GGGCACCCCAGATGAGCATC

Product: glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 504; Mature: 503

Protein sequence:

>504_residues
MGEMYDLLVIGGGINGVGIARDAAGRGLSVCLCEQDDLAAHTSSASTKLIHGGLRYLEQYEFALVGKALAEREVLLRLAP
HIIWPLRFLLPHQPHLRPAWMIRAGLFLYDHLGGSKRSLPRSRRLSLRTHPVGAPLQESLRTGFVYSDAWVQDARLVVLN
AMDAARRGAKIHTRTRCVGAWHDAGFWYAELEDREGRRRTVQARALANAAGPWAVAFLDTVASVPHEHALRLVKGSHIVV
PKLFDHDHAYIFQQPDRRIVFAIPYEHDFTLIGTTDVDYEADPAAPKIDAAEVQYLCDAVNLYFQQQISPADVVWNYSGV
RPLLDDAEDNAAEVTRDYQLEVVTEGAPLLNVFGGKLTTYRKLAEEAVDRLTHALGARKPAWTARGEALPGGEQRDIASL
LERVGRGRPWLPAATAQRLVRNYGTCAEQLLGDAQSLADLGTHFGADLYQAEVDYLRQHEWAVAADDILWRRSKLGLRID
AAGRQRLEDYLQTQSIRQRDAVSA

Sequences:

>Translated_504_residues
MGEMYDLLVIGGGINGVGIARDAAGRGLSVCLCEQDDLAAHTSSASTKLIHGGLRYLEQYEFALVGKALAEREVLLRLAP
HIIWPLRFLLPHQPHLRPAWMIRAGLFLYDHLGGSKRSLPRSRRLSLRTHPVGAPLQESLRTGFVYSDAWVQDARLVVLN
AMDAARRGAKIHTRTRCVGAWHDAGFWYAELEDREGRRRTVQARALANAAGPWAVAFLDTVASVPHEHALRLVKGSHIVV
PKLFDHDHAYIFQQPDRRIVFAIPYEHDFTLIGTTDVDYEADPAAPKIDAAEVQYLCDAVNLYFQQQISPADVVWNYSGV
RPLLDDAEDNAAEVTRDYQLEVVTEGAPLLNVFGGKLTTYRKLAEEAVDRLTHALGARKPAWTARGEALPGGEQRDIASL
LERVGRGRPWLPAATAQRLVRNYGTCAEQLLGDAQSLADLGTHFGADLYQAEVDYLRQHEWAVAADDILWRRSKLGLRID
AAGRQRLEDYLQTQSIRQRDAVSA
>Mature_503_residues
GEMYDLLVIGGGINGVGIARDAAGRGLSVCLCEQDDLAAHTSSASTKLIHGGLRYLEQYEFALVGKALAEREVLLRLAPH
IIWPLRFLLPHQPHLRPAWMIRAGLFLYDHLGGSKRSLPRSRRLSLRTHPVGAPLQESLRTGFVYSDAWVQDARLVVLNA
MDAARRGAKIHTRTRCVGAWHDAGFWYAELEDREGRRRTVQARALANAAGPWAVAFLDTVASVPHEHALRLVKGSHIVVP
KLFDHDHAYIFQQPDRRIVFAIPYEHDFTLIGTTDVDYEADPAAPKIDAAEVQYLCDAVNLYFQQQISPADVVWNYSGVR
PLLDDAEDNAAEVTRDYQLEVVTEGAPLLNVFGGKLTTYRKLAEEAVDRLTHALGARKPAWTARGEALPGGEQRDIASLL
ERVGRGRPWLPAATAQRLVRNYGTCAEQLLGDAQSLADLGTHFGADLYQAEVDYLRQHEWAVAADDILWRRSKLGLRIDA
AGRQRLEDYLQTQSIRQRDAVSA

Specific function: Conversion Of Glycerol 3-Phosphate To Dihydroxyacetone. Uses Molecular Oxygen Or Nitrate As Electron Acceptor. [C]

COG id: COG0578

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI285002233, Length=528, Percent_Identity=29.1666666666667, Blast_Score=164, Evalue=1e-40,
Organism=Homo sapiens, GI285002231, Length=528, Percent_Identity=29.1666666666667, Blast_Score=164, Evalue=1e-40,
Organism=Escherichia coli, GI2367226, Length=468, Percent_Identity=51.0683760683761, Blast_Score=464, Evalue=1e-132,
Organism=Escherichia coli, GI1788574, Length=397, Percent_Identity=28.7153652392947, Blast_Score=79, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI115534726, Length=515, Percent_Identity=31.0679611650485, Blast_Score=167, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI17509253, Length=531, Percent_Identity=29.9435028248588, Blast_Score=154, Evalue=1e-37,
Organism=Saccharomyces cerevisiae, GI6322036, Length=534, Percent_Identity=29.0262172284644, Blast_Score=150, Evalue=5e-37,
Organism=Drosophila melanogaster, GI161077125, Length=466, Percent_Identity=31.7596566523605, Blast_Score=160, Evalue=1e-39,
Organism=Drosophila melanogaster, GI24653942, Length=466, Percent_Identity=31.7596566523605, Blast_Score=160, Evalue=1e-39,
Organism=Drosophila melanogaster, GI24653944, Length=466, Percent_Identity=31.7596566523605, Blast_Score=160, Evalue=1e-39,
Organism=Drosophila melanogaster, GI20130025, Length=466, Percent_Identity=31.7596566523605, Blast_Score=160, Evalue=1e-39,
Organism=Drosophila melanogaster, GI24586295, Length=507, Percent_Identity=28.0078895463511, Blast_Score=116, Evalue=4e-26,
Organism=Drosophila melanogaster, GI19921278, Length=515, Percent_Identity=25.631067961165, Blast_Score=100, Evalue=4e-21,
Organism=Drosophila melanogaster, GI45550977, Length=366, Percent_Identity=23.7704918032787, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR000447 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.1.5.3 [H]

Molecular weight: Translated: 56090; Mature: 55959

Theoretical pI: Translated: 6.91; Mature: 6.91

Prosite motif: PS00977 FAD_G3PDH_1 ; PS00978 FAD_G3PDH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGEMYDLLVIGGGINGVGIARDAAGRGLSVCLCEQDDLAAHTSSASTKLIHGGLRYLEQY
CCCEEEEEEECCCCCCCEEECCCCCCCCEEEEECCCCCHHCCCCCCHHHHHHHHHHHHHH
EFALVGKALAEREVLLRLAPHIIWPLRFLLPHQPHLRPAWMIRAGLFLYDHLGGSKRSLP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCC
RSRRLSLRTHPVGAPLQESLRTGFVYSDAWVQDARLVVLNAMDAARRGAKIHTRTRCVGA
HHHCCEEEECCCCCCHHHHHHCCCEEECCHHCCCEEEEEECHHHHHCCCEEEEHHHEEEC
WHDAGFWYAELEDREGRRRTVQARALANAAGPWAVAFLDTVASVPHEHALRLVKGSHIVV
EECCCEEEEEECCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHCCCEEEE
PKLFDHDHAYIFQQPDRRIVFAIPYEHDFTLIGTTDVDYEADPAAPKIDAAEVQYLCDAV
EEEECCCCEEEEECCCCEEEEEECCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHH
NLYFQQQISPADVVWNYSGVRPLLDDAEDNAAEVTRDYQLEVVTEGAPLLNVFGGKLTTY
HHHHHHCCCHHHEEECCCCCCHHHCCCCCCHHHHCCCEEEEEEECCCCCHHHCCCCHHHH
RKLAEEAVDRLTHALGARKPAWTARGEALPGGEQRDIASLLERVGRGRPWLPAATAQRLV
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHH
RNYGTCAEQLLGDAQSLADLGTHFGADLYQAEVDYLRQHEWAVAADDILWRRSKLGLRID
HHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHCCCCEEHHHHHHHHHHCCEEEE
AAGRQRLEDYLQTQSIRQRDAVSA
HHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
GEMYDLLVIGGGINGVGIARDAAGRGLSVCLCEQDDLAAHTSSASTKLIHGGLRYLEQY
CCEEEEEEECCCCCCCEEECCCCCCCCEEEEECCCCCHHCCCCCCHHHHHHHHHHHHHH
EFALVGKALAEREVLLRLAPHIIWPLRFLLPHQPHLRPAWMIRAGLFLYDHLGGSKRSLP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCC
RSRRLSLRTHPVGAPLQESLRTGFVYSDAWVQDARLVVLNAMDAARRGAKIHTRTRCVGA
HHHCCEEEECCCCCCHHHHHHCCCEEECCHHCCCEEEEEECHHHHHCCCEEEEHHHEEEC
WHDAGFWYAELEDREGRRRTVQARALANAAGPWAVAFLDTVASVPHEHALRLVKGSHIVV
EECCCEEEEEECCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHCCCEEEE
PKLFDHDHAYIFQQPDRRIVFAIPYEHDFTLIGTTDVDYEADPAAPKIDAAEVQYLCDAV
EEEECCCCEEEEECCCCEEEEEECCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHH
NLYFQQQISPADVVWNYSGVRPLLDDAEDNAAEVTRDYQLEVVTEGAPLLNVFGGKLTTY
HHHHHHCCCHHHEEECCCCCCHHHCCCCCCHHHHCCCEEEEEEECCCCCHHHCCCCHHHH
RKLAEEAVDRLTHALGARKPAWTARGEALPGGEQRDIASLLERVGRGRPWLPAATAQRLV
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHH
RNYGTCAEQLLGDAQSLADLGTHFGADLYQAEVDYLRQHEWAVAADDILWRRSKLGLRID
HHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHCCCCEEHHHHHHHHHHCCEEEE
AAGRQRLEDYLQTQSIRQRDAVSA
HHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8157588; 10984043 [H]