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The map label for this gene is yafC [C]

Identifier: 78045867

GI number: 78045867

Start: 355084

End: 356088

Strand: Reverse

Name: yafC [C]

Synonym: XCV0311

Alternate gene names: 78045867

Gene position: 356088-355084 (Counterclockwise)

Preceding gene: 78045869

Following gene: 78045866

Centisome position: 6.88

GC content: 66.17

Gene sequence:

>1005_bases
ATGCGCTGCATGGCGCATGCGGCATCCAGGGGTTGCTCACATCGGGCTGCTAGGCTGCGTGCCCGGTCGAAGGTGATTGT
CGAAGTCGAGGCGCAGGTGGACCGCATCCAGGAAATGACGCTGTTTGCCGCGCTGGCCGAGCACACAAGCTTTGCGGGTG
TCGCACGCCGTCTCGGCATTTCCACCGCCACAGTCACGCGCACCATCGCGCAGCTGGAAGCGCGGCTGGGCGTGCTGCTG
GTGGTGCGCAGCACACGCACCATGCGGTTCACCGCGGCAGGCCAGCAGTATGCAAGCGACTGCCGGCGCCTGTTGGCCGA
GCTGGAGGATGTCGAAAGCCGCGCCGCTGGGCTGCATACGCTCCCCAGCGGCTTGCTCACCGTGACTGCCCCGCAGATGT
TCGGTGCACTGCATGTCACACCTGTCGTAGCGCACTTCCTCAGCCGTTACCCGGCGATGCGCGCACGGACACTGCTGGTG
GACCGCGTCGTGCCGCTGCTGGAGGAAGGCATCGATGTGGCGATCCGGATCGGCACGTTGCCCGATTCGTCGCTGACTGC
CATCCCGGTCGGCAGCGTCCGTCGCATGGTCTGTGCCTCGCCCGGCTATCTTGCAGAACACGGCATACCGCAGCACCCGG
ACAGGCTGCCGCAGCATGCAACGATTTCCACCTCCGCGGCCGAACGCGCGCCCAAGTGGGCGTTTCGTCTGGATGGCCGT
GCGCATGAGGTGGACGTTGCCTCGCGCCTGAGCGTCAGCGCATTCAACGCCGCCATCGTTGCCGCAGTGGATGGGTGGGG
CCTCACGCAAGTGCCGTCCTACCAGGTCCGCCAACACCTGCAAAACGGAACGCTGGTCAGCGTGCTGGATGCCTTCGAAA
TCGCGCCCGAACCGGTGCACGTGGTCCATGTCGAAGGCCGCCGCGGCTCGTCGAAGGTGCGCACCTTCGTGGACGAGTGC
GTGGCTGCGTTACGGCACGACCTTGGATGTGCGGACGGCGGTTGA

Upstream 100 bases:

>100_bases
ATGGCGGCCATGCTAGGTGCGCCGGTCCAGCACGAGAACCACCCTGGGGTTCAATTGAGCATTGCATCGCACGCAATGCC
GCGGCCACTGTTGCGTTTGC

Downstream 100 bases:

>100_bases
GCGGCGCCAGGCAGCCCCGCCATGCCGTTGGCTGCCGCACGCGCGCGAAGGCGCGCCTGACCGCAACAACGCCATGCAGT
CGATCAGCTGACGCAGTTGC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: ORF2 [H]

Number of amino acids: Translated: 334; Mature: 334

Protein sequence:

>334_residues
MRCMAHAASRGCSHRAARLRARSKVIVEVEAQVDRIQEMTLFAALAEHTSFAGVARRLGISTATVTRTIAQLEARLGVLL
VVRSTRTMRFTAAGQQYASDCRRLLAELEDVESRAAGLHTLPSGLLTVTAPQMFGALHVTPVVAHFLSRYPAMRARTLLV
DRVVPLLEEGIDVAIRIGTLPDSSLTAIPVGSVRRMVCASPGYLAEHGIPQHPDRLPQHATISTSAAERAPKWAFRLDGR
AHEVDVASRLSVSAFNAAIVAAVDGWGLTQVPSYQVRQHLQNGTLVSVLDAFEIAPEPVHVVHVEGRRGSSKVRTFVDEC
VAALRHDLGCADGG

Sequences:

>Translated_334_residues
MRCMAHAASRGCSHRAARLRARSKVIVEVEAQVDRIQEMTLFAALAEHTSFAGVARRLGISTATVTRTIAQLEARLGVLL
VVRSTRTMRFTAAGQQYASDCRRLLAELEDVESRAAGLHTLPSGLLTVTAPQMFGALHVTPVVAHFLSRYPAMRARTLLV
DRVVPLLEEGIDVAIRIGTLPDSSLTAIPVGSVRRMVCASPGYLAEHGIPQHPDRLPQHATISTSAAERAPKWAFRLDGR
AHEVDVASRLSVSAFNAAIVAAVDGWGLTQVPSYQVRQHLQNGTLVSVLDAFEIAPEPVHVVHVEGRRGSSKVRTFVDEC
VAALRHDLGCADGG
>Mature_334_residues
MRCMAHAASRGCSHRAARLRARSKVIVEVEAQVDRIQEMTLFAALAEHTSFAGVARRLGISTATVTRTIAQLEARLGVLL
VVRSTRTMRFTAAGQQYASDCRRLLAELEDVESRAAGLHTLPSGLLTVTAPQMFGALHVTPVVAHFLSRYPAMRARTLLV
DRVVPLLEEGIDVAIRIGTLPDSSLTAIPVGSVRRMVCASPGYLAEHGIPQHPDRLPQHATISTSAAERAPKWAFRLDGR
AHEVDVASRLSVSAFNAAIVAAVDGWGLTQVPSYQVRQHLQNGTLVSVLDAFEIAPEPVHVVHVEGRRGSSKVRTFVDEC
VAALRHDLGCADGG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=293, Percent_Identity=31.3993174061433, Blast_Score=141, Evalue=6e-35,
Organism=Escherichia coli, GI1789639, Length=289, Percent_Identity=28.719723183391, Blast_Score=135, Evalue=5e-33,
Organism=Escherichia coli, GI145693193, Length=299, Percent_Identity=28.7625418060201, Blast_Score=131, Evalue=6e-32,
Organism=Escherichia coli, GI87081978, Length=284, Percent_Identity=29.2253521126761, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI1787128, Length=286, Percent_Identity=23.4265734265734, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1789440, Length=300, Percent_Identity=25.6666666666667, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1787589, Length=288, Percent_Identity=25, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1788706, Length=294, Percent_Identity=24.1496598639456, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1789173, Length=285, Percent_Identity=24.9122807017544, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1787879, Length=156, Percent_Identity=30.7692307692308, Blast_Score=68, Evalue=8e-13,
Organism=Escherichia coli, GI157672245, Length=155, Percent_Identity=30.9677419354839, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1786713, Length=255, Percent_Identity=29.0196078431373, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 36031; Mature: 36031

Theoretical pI: Translated: 9.11; Mature: 9.11

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRCMAHAASRGCSHRAARLRARSKVIVEVEAQVDRIQEMTLFAALAEHTSFAGVARRLGI
CCCHHHHHHCCHHHHHHHHHHCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
STATVTRTIAQLEARLGVLLVVRSTRTMRFTAAGQQYASDCRRLLAELEDVESRAAGLHT
CHHHHHHHHHHHHHHHCEEEEEECCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCHH
LPSGLLTVTAPQMFGALHVTPVVAHFLSRYPAMRARTLLVDRVVPLLEEGIDVAIRIGTL
CCCCCEEEECHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCEEEEEEECC
PDSSLTAIPVGSVRRMVCASPGYLAEHGIPQHPDRLPQHATISTSAAERAPKWAFRLDGR
CCCCEEEECHHHHHHHHHCCCCCHHHCCCCCCCCCCCCCCEECCHHHHCCCCEEEEECCC
AHEVDVASRLSVSAFNAAIVAAVDGWGLTQVPSYQVRQHLQNGTLVSVLDAFEIAPEPVH
CCEEHHHHHHHHHHHCEEEEEEECCCCCCCCCCHHHHHHHCCCCHHHHHHHHHCCCCCEE
VVHVEGRRGSSKVRTFVDECVAALRHDLGCADGG
EEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MRCMAHAASRGCSHRAARLRARSKVIVEVEAQVDRIQEMTLFAALAEHTSFAGVARRLGI
CCCHHHHHHCCHHHHHHHHHHCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
STATVTRTIAQLEARLGVLLVVRSTRTMRFTAAGQQYASDCRRLLAELEDVESRAAGLHT
CHHHHHHHHHHHHHHHCEEEEEECCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCHH
LPSGLLTVTAPQMFGALHVTPVVAHFLSRYPAMRARTLLVDRVVPLLEEGIDVAIRIGTL
CCCCCEEEECHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCEEEEEEECC
PDSSLTAIPVGSVRRMVCASPGYLAEHGIPQHPDRLPQHATISTSAAERAPKWAFRLDGR
CCCCEEEECHHHHHHHHHCCCCCHHHCCCCCCCCCCCCCCEECCHHHHCCCCEEEEECCC
AHEVDVASRLSVSAFNAAIVAAVDGWGLTQVPSYQVRQHLQNGTLVSVLDAFEIAPEPVH
CCEEHHHHHHHHHHHCEEEEEEECCCCCCCCCCHHHHHHHCCCCHHHHHHHHHCCCCCEE
VVHVEGRRGSSKVRTFVDECVAALRHDLGCADGG
EEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8635745; 7542800 [H]