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The map label for this gene is dxs [C]

Identifier: 78045200

GI number: 78045200

Start: 139840

End: 140778

Strand: Direct

Name: dxs [C]

Synonym: CHY_0166

Alternate gene names: 78045200

Gene position: 139840-140778 (Clockwise)

Preceding gene: 78044530

Following gene: 78044008

Centisome position: 5.82

GC content: 50.8

Gene sequence:

>939_bases
GTGGGAGGAATAGCCACAAGGGAAGCATACGGAAAGGCCCTGGTTGAATTGGGGCAGGAAAACCCGAAAATCGTTGTTTT
AGATGCGGACTTATCTAAGTCCACGAAAACCTCCGATTTTGCCAAAGCTTTTCCCGAGAGATTTTTTAACATGGGCATTG
CTGAGCAAAATTTAATGGGGGTTGCTGCCGGTCTTTCTACGGTGGGGAAAATACCCTTTGCCAGTACCTTTGCGGTGTTT
GCGGCGGGCAGAGCGTTTGAAATAATTCGAAACAGTATCTGTTACCCGAAGCTCAATGTGAAAATTGCTGCTACCCATGC
GGGTTTAACGGTGGGGGAAGACGGAGCTTCCCACCAGGCAATAGAAGATCTGGCTTTGATGCGGGTTTTACCCAATATGC
AGGTATTTGTACCCGCCGATGCCGCCCAGACCCGTGCTATTGTAAAAAAAGCTGCGGAAATAGAGGGTCCGGTTTACATC
CGTCTTGGCCGTTCCGGGGTGCCGGAGGTGTTTTCGCCAGATATTCGGTTTGAACCGGGGCGGGGTACGGTGCTTAAAGA
AGGTAAAGATGTAACTATAGTTGCTCTCGGGATTATGACGGCCAAAGCGTTAGAGGCAGCTAAGATGTTAGAGGCAGAAG
GCATCGCGGCAAGGGTTGTGGACATGGCAAGCCTTAAGCCCATAGACCGGGAGCTTTTGGTGGAAAGCGCTCGACTTACG
GGAGCTGTGGTAACGGCGGAGGAACATTCGGTTATTGGCGGACTTGGCAGTGCGGTGGCGGAGGTTTTAAGCGAGGAGTA
TCCGATACCGGTGGTAAAAGTAGGAGTTAATGATGTGTTTGGGGAGTCGGGAACTCCGCAAGCGCTTTTGGAAAAATACG
GCTTAACCGCCAGGGACGTTGTAGCGGCGGTGCAAAAAGCGTTAACCTTAAAAAGGTAA

Upstream 100 bases:

>100_bases
TTTCCTTCATGGAAAACCGGGTCGAGTGGCATGGATCTGCTCCCAAACCGGAGCAGGTAGCAGAGGCTCTTTCTGAACTT
CAAGTGGGGAGGGAAAAGCT

Downstream 100 bases:

>100_bases
CTCCGGGGACGGTTCTGAGAACATCCATTTTCCGCTCACGAACCGTCCTTTAATTTTTTTGCTTAAAAACAAGGAAAAAG
CCATAACTTTGTCGAATAAA

Product: putative transketolase, C-terminal subunit

Products: NA

Alternate protein names: TK [H]

Number of amino acids: Translated: 312; Mature: 311

Protein sequence:

>312_residues
MGGIATREAYGKALVELGQENPKIVVLDADLSKSTKTSDFAKAFPERFFNMGIAEQNLMGVAAGLSTVGKIPFASTFAVF
AAGRAFEIIRNSICYPKLNVKIAATHAGLTVGEDGASHQAIEDLALMRVLPNMQVFVPADAAQTRAIVKKAAEIEGPVYI
RLGRSGVPEVFSPDIRFEPGRGTVLKEGKDVTIVALGIMTAKALEAAKMLEAEGIAARVVDMASLKPIDRELLVESARLT
GAVVTAEEHSVIGGLGSAVAEVLSEEYPIPVVKVGVNDVFGESGTPQALLEKYGLTARDVVAAVQKALTLKR

Sequences:

>Translated_312_residues
MGGIATREAYGKALVELGQENPKIVVLDADLSKSTKTSDFAKAFPERFFNMGIAEQNLMGVAAGLSTVGKIPFASTFAVF
AAGRAFEIIRNSICYPKLNVKIAATHAGLTVGEDGASHQAIEDLALMRVLPNMQVFVPADAAQTRAIVKKAAEIEGPVYI
RLGRSGVPEVFSPDIRFEPGRGTVLKEGKDVTIVALGIMTAKALEAAKMLEAEGIAARVVDMASLKPIDRELLVESARLT
GAVVTAEEHSVIGGLGSAVAEVLSEEYPIPVVKVGVNDVFGESGTPQALLEKYGLTARDVVAAVQKALTLKR
>Mature_311_residues
GGIATREAYGKALVELGQENPKIVVLDADLSKSTKTSDFAKAFPERFFNMGIAEQNLMGVAAGLSTVGKIPFASTFAVFA
AGRAFEIIRNSICYPKLNVKIAATHAGLTVGEDGASHQAIEDLALMRVLPNMQVFVPADAAQTRAIVKKAAEIEGPVYIR
LGRSGVPEVFSPDIRFEPGRGTVLKEGKDVTIVALGIMTAKALEAAKMLEAEGIAARVVDMASLKPIDRELLVESARLTG
AVVTAEEHSVIGGLGSAVAEVLSEEYPIPVVKVGVNDVFGESGTPQALLEKYGLTARDVVAAVQKALTLKR

Specific function: Catalyzes The Acyloin Condensation Reaction Between C Atoms 2 And 3 Of Pyruvate And Glyceraldehyde 3-Phosphate To Yield 1-Deoxy-D-Xylulose-5-Phosphate (Dxp). [C]

COG id: COG3958

COG function: function code G; Transketolase, C-terminal subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transketolase family [H]

Homologues:

Organism=Homo sapiens, GI225637463, Length=309, Percent_Identity=40.453074433657, Blast_Score=209, Evalue=3e-54,
Organism=Homo sapiens, GI205277463, Length=312, Percent_Identity=39.1025641025641, Blast_Score=208, Evalue=4e-54,
Organism=Homo sapiens, GI4507521, Length=312, Percent_Identity=39.1025641025641, Blast_Score=208, Evalue=4e-54,
Organism=Homo sapiens, GI225637459, Length=309, Percent_Identity=40.453074433657, Blast_Score=208, Evalue=4e-54,
Organism=Homo sapiens, GI225637461, Length=309, Percent_Identity=40.453074433657, Blast_Score=208, Evalue=5e-54,
Organism=Homo sapiens, GI133778974, Length=312, Percent_Identity=36.8589743589744, Blast_Score=190, Evalue=2e-48,
Organism=Homo sapiens, GI291084858, Length=326, Percent_Identity=22.3926380368098, Blast_Score=66, Evalue=5e-11,
Organism=Escherichia coli, GI1786622, Length=302, Percent_Identity=31.7880794701987, Blast_Score=151, Evalue=6e-38,
Organism=Escherichia coli, GI48994911, Length=320, Percent_Identity=28.125, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI1788808, Length=332, Percent_Identity=30.421686746988, Blast_Score=89, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17539652, Length=307, Percent_Identity=39.7394136807818, Blast_Score=204, Evalue=4e-53,
Organism=Caenorhabditis elegans, GI17538422, Length=332, Percent_Identity=25.9036144578313, Blast_Score=72, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6325331, Length=340, Percent_Identity=28.5294117647059, Blast_Score=100, Evalue=4e-22,
Organism=Saccharomyces cerevisiae, GI6319593, Length=250, Percent_Identity=29.2, Blast_Score=86, Evalue=5e-18,
Organism=Saccharomyces cerevisiae, GI6319698, Length=284, Percent_Identity=23.943661971831, Blast_Score=64, Evalue=3e-11,
Organism=Drosophila melanogaster, GI45551847, Length=309, Percent_Identity=38.5113268608414, Blast_Score=193, Evalue=1e-49,
Organism=Drosophila melanogaster, GI45550715, Length=309, Percent_Identity=38.5113268608414, Blast_Score=193, Evalue=1e-49,
Organism=Drosophila melanogaster, GI24645119, Length=309, Percent_Identity=38.5113268608414, Blast_Score=193, Evalue=1e-49,
Organism=Drosophila melanogaster, GI24666278, Length=304, Percent_Identity=36.8421052631579, Blast_Score=185, Evalue=3e-47,
Organism=Drosophila melanogaster, GI160714832, Length=237, Percent_Identity=24.4725738396624, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI160714828, Length=237, Percent_Identity=24.4725738396624, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005475
- InterPro:   IPR020826
- InterPro:   IPR005476 [H]

Pfam domain/function: PF02779 Transket_pyr; PF02780 Transketolase_C [H]

EC number: =2.2.1.1 [H]

Molecular weight: Translated: 32903; Mature: 32771

Theoretical pI: Translated: 5.86; Mature: 5.86

Prosite motif: PS00802 TRANSKETOLASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGGIATREAYGKALVELGQENPKIVVLDADLSKSTKTSDFAKAFPERFFNMGIAEQNLMG
CCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHH
VAAGLSTVGKIPFASTFAVFAAGRAFEIIRNSICYPKLNVKIAATHAGLTVGEDGASHQA
HHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHCCCCCCCCEEEEEEECCCEECCCCCCHHH
IEDLALMRVLPNMQVFVPADAAQTRAIVKKAAEIEGPVYIRLGRSGVPEVFSPDIRFEPG
HHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHCCCCEEECC
RGTVLKEGKDVTIVALGIMTAKALEAAKMLEAEGIAARVVDMASLKPIDRELLVESARLT
CCCEEECCCCEEEEEEHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHC
GAVVTAEEHSVIGGLGSAVAEVLSEEYPIPVVKVGVNDVFGESGTPQALLEKYGLTARDV
EEEEEECCCHHHHHHHHHHHHHHHCCCCCCEEEECCHHHCCCCCCHHHHHHHHCCCHHHH
VAAVQKALTLKR
HHHHHHHHHCCC
>Mature Secondary Structure 
GGIATREAYGKALVELGQENPKIVVLDADLSKSTKTSDFAKAFPERFFNMGIAEQNLMG
CCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHH
VAAGLSTVGKIPFASTFAVFAAGRAFEIIRNSICYPKLNVKIAATHAGLTVGEDGASHQA
HHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHCCCCCCCCEEEEEEECCCEECCCCCCHHH
IEDLALMRVLPNMQVFVPADAAQTRAIVKKAAEIEGPVYIRLGRSGVPEVFSPDIRFEPG
HHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHCCCCEEECC
RGTVLKEGKDVTIVALGIMTAKALEAAKMLEAEGIAARVVDMASLKPIDRELLVESARLT
CCCEEECCCCEEEEEEHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHC
GAVVTAEEHSVIGGLGSAVAEVLSEEYPIPVVKVGVNDVFGESGTPQALLEKYGLTARDV
EEEEEECCCHHHHHHHHHHHHHHHCCCCCCEEEECCHHHCCCCCCHHHHHHHHCCCHHHH
VAAVQKALTLKR
HHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]