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The map label for this gene is tktA [C]

Identifier: 78044530

GI number: 78044530

Start: 139010

End: 139852

Strand: Direct

Name: tktA [C]

Synonym: CHY_0165

Alternate gene names: 78044530

Gene position: 139010-139852 (Clockwise)

Preceding gene: 78042996

Following gene: 78045200

Centisome position: 5.79

GC content: 51.72

Gene sequence:

>843_bases
GTGCAGGACGAAATTTTAAACTTAAAGTTAATAGCCAATCAACTCCGCCAGCATGTGGTAAAGATGGTGGGAGAGGCCAA
TTCGGGCCATCCCGGCGGCTCCCTTTCGGCTGCGGATATTTTAGCGGTGCTGTTTTTTAAGGAGATGCGGATTGATCCGG
CTAATCCCAAATGGCAGGACCGGGACCGCTTCGTTTTGAGCAAGGGACATGCTTCCCCGGTTTTATACGCAGCTCTGGCG
GAACGGGGCTTTTTTCCTAAAGAATGGCTGTCCCAATTTCGCAAGATTAATTCTCCCCTGCAGGGGCATCCGGATATGAA
AAAAGTCCCCGGCGTGGAAATGTCCACCGGTTCCCTGGGCCAGGGGTTTTCCACCGCGGTGGGGATGGCTTTAGGGTTAA
AGCTTGACCGCAGCCCGGCCCGGGTTTACGTGCTGCTGGGAGATGGGGAAATTCAGGAAGGGATAGTCTGGGAAGCGGCC
ATGGCCGCAGCCCATTATAAATTAAATAATCTTACGGCGATTTTGGATTACAACGGTCTGCAGATAGACGGGCCGGTGCA
GGAAGTGATGAATCCTGAACCGGTTGCGGATAAATGGCGAAGCTTTGGTTTTAAAGTTATTACCGTTGACGGCCATAACA
TTCCGGAAATAATAAATGCCATCGATGCTGCCCGCCTGCACTTGGAAGGTCCAACCATCATTATCGCCAAGACCGTTAAA
GGTAAAGGAGTTTCCTTCATGGAAAACCGGGTCGAGTGGCATGGATCTGCTCCCAAACCGGAGCAGGTAGCAGAGGCTCT
TTCTGAACTTCAAGTGGGGAGGGAAAAGCTGTGGGAGGAATAG

Upstream 100 bases:

>100_bases
AAATAGTTTACCAGATTGATCCCAAAGCTTTTGTGATAGTCACTAACGTCCATGAGGTTTTGGGGGAAGGCTTTAAACCG
ATGGTTAAGGAGGGAAATTA

Downstream 100 bases:

>100_bases
CCACAAGGGAAGCATACGGAAAGGCCCTGGTTGAATTGGGGCAGGAAAACCCGAAAATCGTTGTTTTAGATGCGGACTTA
TCTAAGTCCACGAAAACCTC

Product: putative transketolase, N-terminal subunit

Products: NA

Alternate protein names: TK [H]

Number of amino acids: Translated: 280; Mature: 280

Protein sequence:

>280_residues
MQDEILNLKLIANQLRQHVVKMVGEANSGHPGGSLSAADILAVLFFKEMRIDPANPKWQDRDRFVLSKGHASPVLYAALA
ERGFFPKEWLSQFRKINSPLQGHPDMKKVPGVEMSTGSLGQGFSTAVGMALGLKLDRSPARVYVLLGDGEIQEGIVWEAA
MAAAHYKLNNLTAILDYNGLQIDGPVQEVMNPEPVADKWRSFGFKVITVDGHNIPEIINAIDAARLHLEGPTIIIAKTVK
GKGVSFMENRVEWHGSAPKPEQVAEALSELQVGREKLWEE

Sequences:

>Translated_280_residues
MQDEILNLKLIANQLRQHVVKMVGEANSGHPGGSLSAADILAVLFFKEMRIDPANPKWQDRDRFVLSKGHASPVLYAALA
ERGFFPKEWLSQFRKINSPLQGHPDMKKVPGVEMSTGSLGQGFSTAVGMALGLKLDRSPARVYVLLGDGEIQEGIVWEAA
MAAAHYKLNNLTAILDYNGLQIDGPVQEVMNPEPVADKWRSFGFKVITVDGHNIPEIINAIDAARLHLEGPTIIIAKTVK
GKGVSFMENRVEWHGSAPKPEQVAEALSELQVGREKLWEE
>Mature_280_residues
MQDEILNLKLIANQLRQHVVKMVGEANSGHPGGSLSAADILAVLFFKEMRIDPANPKWQDRDRFVLSKGHASPVLYAALA
ERGFFPKEWLSQFRKINSPLQGHPDMKKVPGVEMSTGSLGQGFSTAVGMALGLKLDRSPARVYVLLGDGEIQEGIVWEAA
MAAAHYKLNNLTAILDYNGLQIDGPVQEVMNPEPVADKWRSFGFKVITVDGHNIPEIINAIDAARLHLEGPTIIIAKTVK
GKGVSFMENRVEWHGSAPKPEQVAEALSELQVGREKLWEE

Specific function: Unknown

COG id: COG3959

COG function: function code G; Transketolase, N-terminal subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transketolase family [H]

Homologues:

Organism=Homo sapiens, GI205277463, Length=269, Percent_Identity=46.4684014869888, Blast_Score=217, Evalue=8e-57,
Organism=Homo sapiens, GI4507521, Length=269, Percent_Identity=46.4684014869888, Blast_Score=217, Evalue=8e-57,
Organism=Homo sapiens, GI133778974, Length=264, Percent_Identity=40.9090909090909, Blast_Score=201, Evalue=6e-52,
Organism=Homo sapiens, GI225637459, Length=275, Percent_Identity=32, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI225637461, Length=275, Percent_Identity=30.9090909090909, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI225637463, Length=242, Percent_Identity=31.8181818181818, Blast_Score=113, Evalue=2e-25,
Organism=Escherichia coli, GI48994911, Length=278, Percent_Identity=37.7697841726619, Blast_Score=165, Evalue=4e-42,
Organism=Escherichia coli, GI1788808, Length=277, Percent_Identity=36.4620938628159, Blast_Score=164, Evalue=7e-42,
Organism=Caenorhabditis elegans, GI17539652, Length=271, Percent_Identity=45.0184501845018, Blast_Score=225, Evalue=2e-59,
Organism=Saccharomyces cerevisiae, GI6325331, Length=283, Percent_Identity=40.2826855123675, Blast_Score=168, Evalue=7e-43,
Organism=Saccharomyces cerevisiae, GI6319593, Length=270, Percent_Identity=37.037037037037, Blast_Score=157, Evalue=1e-39,
Organism=Drosophila melanogaster, GI45551847, Length=268, Percent_Identity=40.6716417910448, Blast_Score=208, Evalue=2e-54,
Organism=Drosophila melanogaster, GI45550715, Length=268, Percent_Identity=40.6716417910448, Blast_Score=208, Evalue=2e-54,
Organism=Drosophila melanogaster, GI24666278, Length=269, Percent_Identity=41.635687732342, Blast_Score=200, Evalue=9e-52,
Organism=Drosophila melanogaster, GI24645119, Length=232, Percent_Identity=41.3793103448276, Blast_Score=184, Evalue=5e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005474 [H]

Pfam domain/function: PF00456 Transketolase_N [H]

EC number: =2.2.1.1 [H]

Molecular weight: Translated: 30806; Mature: 30806

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00801 TRANSKETOLASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQDEILNLKLIANQLRQHVVKMVGEANSGHPGGSLSAADILAVLFFKEMRIDPANPKWQD
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCC
RDRFVLSKGHASPVLYAALAERGFFPKEWLSQFRKINSPLQGHPDMKKVPGVEMSTGSLG
CCCEEEECCCCCHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCHHHCCCCEECCCCCC
QGFSTAVGMALGLKLDRSPARVYVLLGDGEIQEGIVWEAAMAAAHYKLNNLTAILDYNGL
CCHHHHHHHHHCCEECCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHCCEEEEEECCCE
QIDGPVQEVMNPEPVADKWRSFGFKVITVDGHNIPEIINAIDAARLHLEGPTIIIAKTVK
EECCCHHHHCCCCCHHHHHHHCCCEEEEECCCCHHHHHHHHHHHEEEECCCEEEEEECCC
GKGVSFMENRVEWHGSAPKPEQVAEALSELQVGREKLWEE
CCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQDEILNLKLIANQLRQHVVKMVGEANSGHPGGSLSAADILAVLFFKEMRIDPANPKWQD
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCC
RDRFVLSKGHASPVLYAALAERGFFPKEWLSQFRKINSPLQGHPDMKKVPGVEMSTGSLG
CCCEEEECCCCCHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCHHHCCCCEECCCCCC
QGFSTAVGMALGLKLDRSPARVYVLLGDGEIQEGIVWEAAMAAAHYKLNNLTAILDYNGL
CCHHHHHHHHHCCEECCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHCCEEEEEECCCE
QIDGPVQEVMNPEPVADKWRSFGFKVITVDGHNIPEIINAIDAARLHLEGPTIIIAKTVK
EECCCHHHHCCCCCHHHHHHHCCCEEEEECCCCHHHHHHHHHHHEEEECCCEEEEEECCC
GKGVSFMENRVEWHGSAPKPEQVAEALSELQVGREKLWEE
CCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]