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The map label for this gene is resD [H]

Identifier: 78045188

GI number: 78045188

Start: 79413

End: 80117

Strand: Direct

Name: resD [H]

Synonym: CHY_0092

Alternate gene names: 78045188

Gene position: 79413-80117 (Clockwise)

Preceding gene: 78043258

Following gene: 78043821

Centisome position: 3.31

GC content: 44.26

Gene sequence:

>705_bases
ATGAAAAAGGTGCTTATTATCGAAGATGACCGGAGTATTGCGGAACTTGAGCGAGATTATTTGGAAGTGGCGGGGTTTTT
GGTGGAGATTGCAGTTAATGGTGATCAGGGCTTAAAAAAAGCTTTAGAAGAAGAGTATGATTTAATCTTACTGGATTTAA
TGCTTCCGGGAATTGATGGCTTTGAGGTGCTGCGCAAAGTGCGGGCAGAAAAAGATACACCGGTGCTTTTAGTGTCAGCC
CGGCGGGAAGATATCGATAAGATCCGGGGGTTGGGACTGGGAGCGGATGATTATATCACAAAGCCTTTTAGTCCCAGTGA
ACTGGTAGCCCGGGTAAAGGCTCATATAGGCCGTTACGAGCGGTTAACCGGCGGGCGAAAAAATCAAGACCTTTTGGAAT
TTCCGGGTTTAGTGATTGATACCGCTGCCCGCCGGGTTTTTGCAGGAGATAAAGAAGTAAATTTAACCGGGAAAGAATTT
GATTTACTTTTATTTTTAGCTAAAAACCCCAACAGGGTATTTACCAAAGAAGAACTTTTTGAGCGGATTTGGGGTATGGA
CTCCCTGGGCGATTTATCTACAGTTACTGTGCATATTCGAAAACTTCGGGAAAAAATCGAAAAAGATCCCTCTAACCCCC
AGTATATTGAAACCATCTGGGGTGTAGGCTACCGGTTTAGTGGTCTGTGGCCAATTAGAGATTAG

Upstream 100 bases:

>100_bases
CTAAGATTATTGAAGAGCACGGTGGGGAAATTTGGGCCAATAGTGTTTTAAATGAGGGAACCACGATAAGTTTTACCTTG
AAAAAACTGGGGGAAGGCGC

Downstream 100 bases:

>100_bases
AGGTTGGAAAATGGAGGTTAGAGGGAAATTTTCATGTTGACTGGTTACTTCGATTGTTGTCTTTTAACCGGCCGGCCTTT
TTGGCGGCTTCTCGAAGTAA

Product: DNA-binding response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 234; Mature: 234

Protein sequence:

>234_residues
MKKVLIIEDDRSIAELERDYLEVAGFLVEIAVNGDQGLKKALEEEYDLILLDLMLPGIDGFEVLRKVRAEKDTPVLLVSA
RREDIDKIRGLGLGADDYITKPFSPSELVARVKAHIGRYERLTGGRKNQDLLEFPGLVIDTAARRVFAGDKEVNLTGKEF
DLLLFLAKNPNRVFTKEELFERIWGMDSLGDLSTVTVHIRKLREKIEKDPSNPQYIETIWGVGYRFSGLWPIRD

Sequences:

>Translated_234_residues
MKKVLIIEDDRSIAELERDYLEVAGFLVEIAVNGDQGLKKALEEEYDLILLDLMLPGIDGFEVLRKVRAEKDTPVLLVSA
RREDIDKIRGLGLGADDYITKPFSPSELVARVKAHIGRYERLTGGRKNQDLLEFPGLVIDTAARRVFAGDKEVNLTGKEF
DLLLFLAKNPNRVFTKEELFERIWGMDSLGDLSTVTVHIRKLREKIEKDPSNPQYIETIWGVGYRFSGLWPIRD
>Mature_234_residues
MKKVLIIEDDRSIAELERDYLEVAGFLVEIAVNGDQGLKKALEEEYDLILLDLMLPGIDGFEVLRKVRAEKDTPVLLVSA
RREDIDKIRGLGLGADDYITKPFSPSELVARVKAHIGRYERLTGGRKNQDLLEFPGLVIDTAARRVFAGDKEVNLTGKEF
DLLLFLAKNPNRVFTKEELFERIWGMDSLGDLSTVTVHIRKLREKIEKDPSNPQYIETIWGVGYRFSGLWPIRD

Specific function: Member of the two-component regulatory system ResD/ResE. Required for the expression of resA, ctaA, qcrABC and fnr; activation role in global regulation of aerobic and anaerobic respiration [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=229, Percent_Identity=39.3013100436681, Blast_Score=164, Evalue=6e-42,
Organism=Escherichia coli, GI87082012, Length=224, Percent_Identity=39.7321428571429, Blast_Score=163, Evalue=1e-41,
Organism=Escherichia coli, GI1789809, Length=227, Percent_Identity=35.2422907488987, Blast_Score=155, Evalue=2e-39,
Organism=Escherichia coli, GI1786911, Length=226, Percent_Identity=38.9380530973451, Blast_Score=155, Evalue=2e-39,
Organism=Escherichia coli, GI1788394, Length=226, Percent_Identity=37.6106194690265, Blast_Score=151, Evalue=3e-38,
Organism=Escherichia coli, GI1786784, Length=223, Percent_Identity=35.8744394618834, Blast_Score=140, Evalue=7e-35,
Organism=Escherichia coli, GI1790863, Length=230, Percent_Identity=32.1739130434783, Blast_Score=127, Evalue=4e-31,
Organism=Escherichia coli, GI1790860, Length=231, Percent_Identity=34.1991341991342, Blast_Score=124, Evalue=4e-30,
Organism=Escherichia coli, GI2367329, Length=228, Percent_Identity=33.3333333333333, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1789402, Length=223, Percent_Identity=34.0807174887892, Blast_Score=118, Evalue=3e-28,
Organism=Escherichia coli, GI145693140, Length=234, Percent_Identity=32.9059829059829, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1790552, Length=224, Percent_Identity=34.375, Blast_Score=107, Evalue=9e-25,
Organism=Escherichia coli, GI1787229, Length=227, Percent_Identity=30.3964757709251, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1787375, Length=226, Percent_Identity=30.0884955752212, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1788550, Length=109, Percent_Identity=31.1926605504587, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26659; Mature: 26659

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKVLIIEDDRSIAELERDYLEVAGFLVEIAVNGDQGLKKALEEEYDLILLDLMLPGIDG
CCEEEEEECCCHHHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHHCEEEEEHHCCCCCH
FEVLRKVRAEKDTPVLLVSARREDIDKIRGLGLGADDYITKPFSPSELVARVKAHIGRYE
HHHHHHHHCCCCCCEEEEECCHHHHHHHHCCCCCCHHCCCCCCCHHHHHHHHHHHHHHHH
RLTGGRKNQDLLEFPGLVIDTAARRVFAGDKEVNLTGKEFDLLLFLAKNPNRVFTKEELF
HHCCCCCCCHHHHCCCHHHHHHHHHHHCCCCEEEECCCCEEEEEEEECCCCCCCCHHHHH
ERIWGMDSLGDLSTVTVHIRKLREKIEKDPSNPQYIETIWGVGYRFSGLWPIRD
HHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCEEECCCCCCCC
>Mature Secondary Structure
MKKVLIIEDDRSIAELERDYLEVAGFLVEIAVNGDQGLKKALEEEYDLILLDLMLPGIDG
CCEEEEEECCCHHHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHHCEEEEEHHCCCCCH
FEVLRKVRAEKDTPVLLVSARREDIDKIRGLGLGADDYITKPFSPSELVARVKAHIGRYE
HHHHHHHHCCCCCCEEEEECCHHHHHHHHCCCCCCHHCCCCCCCHHHHHHHHHHHHHHHH
RLTGGRKNQDLLEFPGLVIDTAARRVFAGDKEVNLTGKEFDLLLFLAKNPNRVFTKEELF
HHCCCCCCCHHHHCCCHHHHHHHHHHHCCCCEEEECCCCEEEEEEEECCCCCCCCHHHHH
ERIWGMDSLGDLSTVTVHIRKLREKIEKDPSNPQYIETIWGVGYRFSGLWPIRD
HHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715; 8682783 [H]