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The map label for this gene is yusP [H]

Identifier: 78044871

GI number: 78044871

Start: 720756

End: 722357

Strand: Direct

Name: yusP [H]

Synonym: CHY_0814

Alternate gene names: 78044871

Gene position: 720756-722357 (Clockwise)

Preceding gene: 78044832

Following gene: 78042682

Centisome position: 30.01

GC content: 43.63

Gene sequence:

>1602_bases
ATGGACCAGAATTCCAGAAGAAACATTTTACTAATTGGTTTAATCCTCGGGATGTTTTTTTCAGCACTGGACCAAACGGT
GGTCGGCACTGCAATGCCGCGGATTATAGGAGAGCTCGGGGGGCTTGATATTTTATCCTGGGTTACTACTGCATACATGT
TAAGTTCTACCACCTTTGTGCCTATAGCTGGAAAACTTGCCGATATCTACGGCCGGCGGATAATGTATGTATCTGGCCTT
GGCCTTTTTATGCTGGGCTCCGCACTCTGTGGAACCAGTGAAAATATGACCCAGCTTATTATTTACCGCGGTCTTCAGGG
CATTGGTGGAGGAATCTTGATGCCCATGGCTATGACGATTGTAGGCGACGTTTTTCCTCCGGATAAACGGGGCAAATGGC
AGGGGGTAATGGGGGCTTTATTTGGATTGTCATCAATTGTAGGTCCCTCCCTTGGGGGCTGGATTGTTGACCATACCTCC
TGGCGCTGGGTATTTTATATTAACTTACCTGTAGGCATTTTAGCAGCAATTACCGTATTTATTGGCTTAAGTGGGGAAAA
ACGGCTTAAAGCAGAAGCTCCTATTGACTTTGCCGGGGCTTTAACCATGATTATTGCGGTGGCATCTCTTTTACTTGGCT
TAAGTTTGGGAGGTAAAGAATATCCCTGGAATTCCTGGCAAATTATCGGTCTGTTTGCTACTTCCCTGGTATTTTTATTG
ATTTTCTTTAGAGTGGAGAAGACTGCCAGGGAGCCGATTTTAAGCCTGGACCTTTTTAAAAACCGGATTTTTACCGTAGC
CAACCTGGTAGGTTTTTTAATGGGTTTTGGCATGTTTGGGGCAATTATGTTTTTACCGTTATTCATGCAGGGGGTTCTGG
GGATTTCCGCTACCAATTCGGGCAATACAATGATTCCCATGATGTTTGCTATGGTCTTTACCAGTATTTTGGGCGGACAA
TTGGTTTCGAAAGTCGGTTTCAGGAATTTATTGATTACCGGAATGGCTTTAATGACATTAGGCTTTTATTTGCTAAGTAC
TATGACCGTTGACACCACCCGGTTAGTGGTAACTTTGTACATTATAGTTCTGGGATTAGGAATGGGACTGGTGATGCCGA
CCCTGACTATTGCCGTTCAGTACGCTTTCCCCTTAGAACAGCGGGGAGTTGCAACGTCGGCGACCCAGTTTTTTAGAAGT
ATCGGCGGGACTTTTGGTGTAACCATTTTTGGGGTAGTTTTAAATCACCGCTCCATCGAACTTTTAAAGAAAGACTTTTT
GCCGGTAGTGCAAAAAATCCCGGGGCTTGCAACGGGGCCCTTTGCTAATTTTTTGGAAAAAGCCAAAACCGATCCCCAGG
GTTTGTTCAATACCTTACTTCGGCCGGAAGTACTGGAAAAAATACCACCTCAGCTCAAAGAAATTATCGTACCACCTTTA
AAGCATGCTTTAGCTGAATCCATCCATTATGTATTTTGGGTGGCAATGTTTATAATTGTTTTTGGCATTTTTCTCAGCTT
TTTCATGGAAAATATTAAGGTTGAAAAGCAACCAGGAGGAATTATCTCTAAAGAAAAACCGGTGGAAAGTGGAGCAAAAT
AA

Upstream 100 bases:

>100_bases
TTTTCTGGCTTGGTGGAATATTTAGGAGAAAAGGACACCAGCGAGTTAATCAGGCTTTTAAATAAAGCAAGCTATTACTT
TAGAGAGGTGGCAAGATAAA

Downstream 100 bases:

>100_bases
CTGGAAATGATTAAAAGCCTCCCGCAAAACCGGGGGGCTTATTAACATCTAATGGGGGAGGTTATACTGTTGGAAAAAGC
GGTAAAATCGGCGAAACCAA

Product: EmrB/QacA family drug resistance transporter

Products: Proton [Cytoplasm]; multidrug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 533; Mature: 533

Protein sequence:

>533_residues
MDQNSRRNILLIGLILGMFFSALDQTVVGTAMPRIIGELGGLDILSWVTTAYMLSSTTFVPIAGKLADIYGRRIMYVSGL
GLFMLGSALCGTSENMTQLIIYRGLQGIGGGILMPMAMTIVGDVFPPDKRGKWQGVMGALFGLSSIVGPSLGGWIVDHTS
WRWVFYINLPVGILAAITVFIGLSGEKRLKAEAPIDFAGALTMIIAVASLLLGLSLGGKEYPWNSWQIIGLFATSLVFLL
IFFRVEKTAREPILSLDLFKNRIFTVANLVGFLMGFGMFGAIMFLPLFMQGVLGISATNSGNTMIPMMFAMVFTSILGGQ
LVSKVGFRNLLITGMALMTLGFYLLSTMTVDTTRLVVTLYIIVLGLGMGLVMPTLTIAVQYAFPLEQRGVATSATQFFRS
IGGTFGVTIFGVVLNHRSIELLKKDFLPVVQKIPGLATGPFANFLEKAKTDPQGLFNTLLRPEVLEKIPPQLKEIIVPPL
KHALAESIHYVFWVAMFIIVFGIFLSFFMENIKVEKQPGGIISKEKPVESGAK

Sequences:

>Translated_533_residues
MDQNSRRNILLIGLILGMFFSALDQTVVGTAMPRIIGELGGLDILSWVTTAYMLSSTTFVPIAGKLADIYGRRIMYVSGL
GLFMLGSALCGTSENMTQLIIYRGLQGIGGGILMPMAMTIVGDVFPPDKRGKWQGVMGALFGLSSIVGPSLGGWIVDHTS
WRWVFYINLPVGILAAITVFIGLSGEKRLKAEAPIDFAGALTMIIAVASLLLGLSLGGKEYPWNSWQIIGLFATSLVFLL
IFFRVEKTAREPILSLDLFKNRIFTVANLVGFLMGFGMFGAIMFLPLFMQGVLGISATNSGNTMIPMMFAMVFTSILGGQ
LVSKVGFRNLLITGMALMTLGFYLLSTMTVDTTRLVVTLYIIVLGLGMGLVMPTLTIAVQYAFPLEQRGVATSATQFFRS
IGGTFGVTIFGVVLNHRSIELLKKDFLPVVQKIPGLATGPFANFLEKAKTDPQGLFNTLLRPEVLEKIPPQLKEIIVPPL
KHALAESIHYVFWVAMFIIVFGIFLSFFMENIKVEKQPGGIISKEKPVESGAK
>Mature_533_residues
MDQNSRRNILLIGLILGMFFSALDQTVVGTAMPRIIGELGGLDILSWVTTAYMLSSTTFVPIAGKLADIYGRRIMYVSGL
GLFMLGSALCGTSENMTQLIIYRGLQGIGGGILMPMAMTIVGDVFPPDKRGKWQGVMGALFGLSSIVGPSLGGWIVDHTS
WRWVFYINLPVGILAAITVFIGLSGEKRLKAEAPIDFAGALTMIIAVASLLLGLSLGGKEYPWNSWQIIGLFATSLVFLL
IFFRVEKTAREPILSLDLFKNRIFTVANLVGFLMGFGMFGAIMFLPLFMQGVLGISATNSGNTMIPMMFAMVFTSILGGQ
LVSKVGFRNLLITGMALMTLGFYLLSTMTVDTTRLVVTLYIIVLGLGMGLVMPTLTIAVQYAFPLEQRGVATSATQFFRS
IGGTFGVTIFGVVLNHRSIELLKKDFLPVVQKIPGLATGPFANFLEKAKTDPQGLFNTLLRPEVLEKIPPQLKEIIVPPL
KHALAESIHYVFWVAMFIIVFGIFLSFFMENIKVEKQPGGIISKEKPVESGAK

Specific function: Translocase That Confers Resistance To Substances Of High Hydrophobicity. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. EmrB family [H]

Homologues:

Organism=Escherichia coli, GI1789042, Length=413, Percent_Identity=29.2978208232446, Blast_Score=162, Evalue=4e-41,
Organism=Escherichia coli, GI1788710, Length=433, Percent_Identity=28.4064665127021, Blast_Score=147, Evalue=2e-36,
Organism=Escherichia coli, GI1790195, Length=343, Percent_Identity=30.0291545189504, Blast_Score=132, Evalue=7e-32,
Organism=Escherichia coli, GI87081983, Length=411, Percent_Identity=24.8175182481752, Blast_Score=126, Evalue=4e-30,
Organism=Escherichia coli, GI1788392, Length=331, Percent_Identity=31.1178247734139, Blast_Score=115, Evalue=8e-27,
Organism=Escherichia coli, GI1790146, Length=193, Percent_Identity=27.4611398963731, Blast_Score=65, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6319770, Length=400, Percent_Identity=31.75, Blast_Score=157, Evalue=3e-39,
Organism=Saccharomyces cerevisiae, GI6322958, Length=463, Percent_Identity=26.3498920086393, Blast_Score=135, Evalue=2e-32,
Organism=Saccharomyces cerevisiae, GI6323735, Length=304, Percent_Identity=30.2631578947368, Blast_Score=127, Evalue=4e-30,
Organism=Saccharomyces cerevisiae, GI6319783, Length=376, Percent_Identity=26.063829787234, Blast_Score=104, Evalue=3e-23,
Organism=Saccharomyces cerevisiae, GI6324954, Length=417, Percent_Identity=26.8585131894484, Blast_Score=103, Evalue=6e-23,
Organism=Saccharomyces cerevisiae, GI6325455, Length=274, Percent_Identity=27.7372262773723, Blast_Score=102, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6321663, Length=152, Percent_Identity=29.6052631578947, Blast_Score=80, Evalue=9e-16,
Organism=Saccharomyces cerevisiae, GI6323520, Length=364, Percent_Identity=25.2747252747253, Blast_Score=76, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004638
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005829
- InterPro:   IPR001411 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 58004; Mature: 58004

Theoretical pI: Translated: 10.05; Mature: 10.05

Prosite motif: PS50850 MFS ; PS00216 SUGAR_TRANSPORT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDQNSRRNILLIGLILGMFFSALDQTVVGTAMPRIIGELGGLDILSWVTTAYMLSSTTFV
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCEE
PIAGKLADIYGRRIMYVSGLGLFMLGSALCGTSENMTQLIIYRGLQGIGGGILMPMAMTI
ECHHHHHHHHCCCEEEECCHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHH
VGDVFPPDKRGKWQGVMGALFGLSSIVGPSLGGWIVDHTSWRWVFYINLPVGILAAITVF
HHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEECCCEEEEEEEECCHHHHHHHHHH
IGLSGEKRLKAEAPIDFAGALTMIIAVASLLLGLSLGGKEYPWNSWQIIGLFATSLVFLL
HCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHH
IFFRVEKTAREPILSLDLFKNRIFTVANLVGFLMGFGMFGAIMFLPLFMQGVLGISATNS
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEECCC
GNTMIPMMFAMVFTSILGGQLVSKVGFRNLLITGMALMTLGFYLLSTMTVDTTRLVVTLY
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IIVLGLGMGLVMPTLTIAVQYAFPLEQRGVATSATQFFRSIGGTFGVTIFGVVLNHRSIE
HHHHHHHHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHCCHHHH
LLKKDFLPVVQKIPGLATGPFANFLEKAKTDPQGLFNTLLRPEVLEKIPPQLKEIIVPPL
HHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCHHHHHHHHCCHHHHHHCCHHHHHHCCCHH
KHALAESIHYVFWVAMFIIVFGIFLSFFMENIKVEKQPGGIISKEKPVESGAK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEECCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MDQNSRRNILLIGLILGMFFSALDQTVVGTAMPRIIGELGGLDILSWVTTAYMLSSTTFV
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCEE
PIAGKLADIYGRRIMYVSGLGLFMLGSALCGTSENMTQLIIYRGLQGIGGGILMPMAMTI
ECHHHHHHHHCCCEEEECCHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHH
VGDVFPPDKRGKWQGVMGALFGLSSIVGPSLGGWIVDHTSWRWVFYINLPVGILAAITVF
HHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEECCCEEEEEEEECCHHHHHHHHHH
IGLSGEKRLKAEAPIDFAGALTMIIAVASLLLGLSLGGKEYPWNSWQIIGLFATSLVFLL
HCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHH
IFFRVEKTAREPILSLDLFKNRIFTVANLVGFLMGFGMFGAIMFLPLFMQGVLGISATNS
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEECCC
GNTMIPMMFAMVFTSILGGQLVSKVGFRNLLITGMALMTLGFYLLSTMTVDTTRLVVTLY
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IIVLGLGMGLVMPTLTIAVQYAFPLEQRGVATSATQFFRSIGGTFGVTIFGVVLNHRSIE
HHHHHHHHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHCCHHHH
LLKKDFLPVVQKIPGLATGPFANFLEKAKTDPQGLFNTLLRPEVLEKIPPQLKEIIVPPL
HHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCHHHHHHHHCCHHHHHHCCHHHHHHCCCHH
KHALAESIHYVFWVAMFIIVFGIFLSFFMENIKVEKQPGGIISKEKPVESGAK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEECCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; multidrug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + multidrug [Cytoplasm] = Proton [Cytoplasm] + multidrug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]