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The map label for this gene is grdB [H]

Identifier: 78044722

GI number: 78044722

Start: 2141836

End: 2143143

Strand: Direct

Name: grdB [H]

Synonym: CHY_2393

Alternate gene names: 78044722

Gene position: 2141836-2143143 (Clockwise)

Preceding gene: 78044558

Following gene: 78044225

Centisome position: 89.19

GC content: 49.08

Gene sequence:

>1308_bases
GTGGCTAAATTCCGTGTAGTCCATTATTTAAACCAGTTTTTCGGTCAAATAGGCGGCGAAGAAAAAGCAGATACTGCTCC
CCTGAAAAAAGACGGTCCCGTAGGCCCTGGTACCGCTTTAAATGGTGCTTTTAAAGGAGAAGCGGAAGTTGTCGGTACCG
TTATCTGCGGTGATAGCTATTTTGCCGAAAACATGGAAGAAGCCCTTAAGCAAATTCTATCAATGATCAAGGAATATAAT
CCTGACCTGGTGGTCGCCGGTCCCGCTTTTAACGCCGGCCGTTACGGTACCGCCTGCGGGGCGGTTGCCGAAGCGGTAGT
AAAAAATCTTGGCATCCCTGCGGTAACCGGCATGTACCCGGAAAACCCAGGTGTAGAAATGTATAAAAAATCCGTTTACA
TCATAGCTACCGCCGATTCGGCCATCGGTATGCGCAATGCCATCCCCAAAATGGCCGCTCTGGGTCTTAAGCTCTTAAAG
AAAGAAGAAATCGGTACTCCCGAACAGGAAGGCTACATTGCCCGGGGAATTCGGAAAAATTACTTTGCGGAAGAAAGAGG
AGCCAAGCGGGCAGTAGACATGCTTATCGCCAAAATCAAGGGAGAAAATTTTACTACCGAACTTCCTATGCCTGCTTTTG
ACCGGGTTCCCCCTAATCCCGCCATAAAAGACCTTAGCAAAGCCACCATAGCTCTGGTAACTTCCGGCGGTATTGTTCCC
AAGGGCAATCCCGACCGGATTGAATCGTCGTCAGCTTCAAAGTTCGGTAAATACTCTATCGCTGGCGTAAAAGACTTAAC
CAGCGATACCTTTGAGACCGCCCATGGCGGCTATGATCCGGTTTACGCCAATCAAGACGCCGACAGAGTTTTACCGGTTG
ACGTTTTAAGGGAAATGGAAGCGGAAGGTAAAATTGGCAAACTGCACGATTACTACTATGCTACCGTTGGTAACGGTACT
TCTGTGGCCAATGCTGCTAAATTCGGTCAGGCCATTGCTGCCGATTTAAAAGCTTCCGGAGTAGATGCGGTCATTCTTAC
CTCCACCTGAGGTACCTGCACTCGCTGCGGTGCAGCGATGGTCAAGGAGATTGAACGGGCCGGTATTCCCGTAGTTCACA
TGTGCACCATCGTTCCCATCAGTAAAACCGTTGGTGCTAACCGAATTGTACCAACCGTTGCTATTCCTCACCCCCTCGGC
AATCCTGCCCTTCCGGCGGATGAGGAAAAAGCTTTAAGAAGAAAACTCGTGGAAAAAGCATTAAAGGCTCTTACCACCGA
AGTGGAAGGGCAAACGGTATTTGACTAA

Upstream 100 bases:

>100_bases
GGAAATGGTTTTAGATGTTGATGCCTTAGCCGCCGAAGTATCCAAAATGAGAAAAGAGGGAAGCAAATATTAGTCCTTGC
TTGGCAAAGGAGGTAATTTT

Downstream 100 bases:

>100_bases
AAAATCCCGGGAGCAGGTCATAAGCCTGCTCCCCAAAATTTAGAAAGCAAGCCCATTATCCGGGCTTAAGATACAAAAAC
AATTTTGACAAACGGAGGTT

Product: glycine reductase, selenoprotein B

Products: NA

Alternate protein names: Selenoprotein PB gamma [H]

Number of amino acids: Translated: 435; Mature: 434

Protein sequence:

>435_residues
MAKFRVVHYLNQFFGQIGGEEKADTAPLKKDGPVGPGTALNGAFKGEAEVVGTVICGDSYFAENMEEALKQILSMIKEYN
PDLVVAGPAFNAGRYGTACGAVAEAVVKNLGIPAVTGMYPENPGVEMYKKSVYIIATADSAIGMRNAIPKMAALGLKLLK
KEEIGTPEQEGYIARGIRKNYFAEERGAKRAVDMLIAKIKGENFTTELPMPAFDRVPPNPAIKDLSKATIALVTSGGIVP
KGNPDRIESSSASKFGKYSIAGVKDLTSDTFETAHGGYDPVYANQDADRVLPVDVLREMEAEGKIGKLHDYYYATVGNGT
SVANAAKFGQAIAADLKASGVDAVILTSTUGTCTRCGAAMVKEIERAGIPVVHMCTIVPISKTVGANRIVPTVAIPHPLG
NPALPADEEKALRRKLVEKALKALTTEVEGQTVFD

Sequences:

>Translated_435_residues
MAKFRVVHYLNQFFGQIGGEEKADTAPLKKDGPVGPGTALNGAFKGEAEVVGTVICGDSYFAENMEEALKQILSMIKEYN
PDLVVAGPAFNAGRYGTACGAVAEAVVKNLGIPAVTGMYPENPGVEMYKKSVYIIATADSAIGMRNAIPKMAALGLKLLK
KEEIGTPEQEGYIARGIRKNYFAEERGAKRAVDMLIAKIKGENFTTELPMPAFDRVPPNPAIKDLSKATIALVTSGGIVP
KGNPDRIESSSASKFGKYSIAGVKDLTSDTFETAHGGYDPVYANQDADRVLPVDVLREMEAEGKIGKLHDYYYATVGNGT
SVANAAKFGQAIAADLKASGVDAVILTST*GTCTRCGAAMVKEIERAGIPVVHMCTIVPISKTVGANRIVPTVAIPHPLG
NPALPADEEKALRRKLVEKALKALTTEVEGQTVFD
>Mature_434_residues
AKFRVVHYLNQFFGQIGGEEKADTAPLKKDGPVGPGTALNGAFKGEAEVVGTVICGDSYFAENMEEALKQILSMIKEYNP
DLVVAGPAFNAGRYGTACGAVAEAVVKNLGIPAVTGMYPENPGVEMYKKSVYIIATADSAIGMRNAIPKMAALGLKLLKK
EEIGTPEQEGYIARGIRKNYFAEERGAKRAVDMLIAKIKGENFTTELPMPAFDRVPPNPAIKDLSKATIALVTSGGIVPK
GNPDRIESSSASKFGKYSIAGVKDLTSDTFETAHGGYDPVYANQDADRVLPVDVLREMEAEGKIGKLHDYYYATVGNGTS
VANAAKFGQAIAADLKASGVDAVILTST*GTCTRCGAAMVKEIERAGIPVVHMCTIVPISKTVGANRIVPTVAIPHPLGN
PALPADEEKALRRKLVEKALKALTTEVEGQTVFD

Specific function: In the first step of glycine reductase, the substrate is bound to component PB via a Schiff base intermediate. Then the PB- activated substrate is nucleophilically attacked by the selenol anion of component PA to transform it to a carboxymethylated seleno

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the grdB/grdF/grdH family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010186
- InterPro:   IPR022787
- InterPro:   IPR010187 [H]

Pfam domain/function: PF07355 GRDB [H]

EC number: =1.21.4.2 [H]

Molecular weight: Translated: 46007; Mature: 45876

Theoretical pI: Translated: 7.02; Mature: 7.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKFRVVHYLNQFFGQIGGEEKADTAPLKKDGPVGPGTALNGAFKGEAEVVGTVICGDSY
CCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCHH
FAENMEEALKQILSMIKEYNPDLVVAGPAFNAGRYGTACGAVAEAVVKNLGIPAVTGMYP
HHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCEECCCC
ENPGVEMYKKSVYIIATADSAIGMRNAIPKMAALGLKLLKKEEIGTPEQEGYIARGIRKN
CCCCHHEEECCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
YFAEERGAKRAVDMLIAKIKGENFTTELPMPAFDRVPPNPAIKDLSKATIALVTSGGIVP
HHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCCCCCCCHHHHHHHHHEEEEEECCCCCC
KGNPDRIESSSASKFGKYSIAGVKDLTSDTFETAHGGYDPVYANQDADRVLPVDVLREME
CCCHHHCCCCCHHHCCCEEECCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHH
AEGKIGKLHDYYYATVGNGTSVANAAKFGQAIAADLKASGVDAVILTSTGTCTRCGAAMV
HCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHH
KEIERAGIPVVHMCTIVPISKTVGANRIVPTVAIPHPLGNPALPADEEKALRRKLVEKAL
HHHHHCCCCEEEHEEEEEHHHHCCCCCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHH
KALTTEVEGQTVFD
HHHHHHCCCCCCCC
>Mature Secondary Structure 
AKFRVVHYLNQFFGQIGGEEKADTAPLKKDGPVGPGTALNGAFKGEAEVVGTVICGDSY
CCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCHH
FAENMEEALKQILSMIKEYNPDLVVAGPAFNAGRYGTACGAVAEAVVKNLGIPAVTGMYP
HHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCEECCCC
ENPGVEMYKKSVYIIATADSAIGMRNAIPKMAALGLKLLKKEEIGTPEQEGYIARGIRKN
CCCCHHEEECCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
YFAEERGAKRAVDMLIAKIKGENFTTELPMPAFDRVPPNPAIKDLSKATIALVTSGGIVP
HHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCCCCCCCHHHHHHHHHEEEEEECCCCCC
KGNPDRIESSSASKFGKYSIAGVKDLTSDTFETAHGGYDPVYANQDADRVLPVDVLREME
CCCHHHCCCCCHHHCCCEEECCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHH
AEGKIGKLHDYYYATVGNGTSVANAAKFGQAIAADLKASGVDAVILTSTGTCTRCGAAMV
HCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHH
KEIERAGIPVVHMCTIVPISKTVGANRIVPTVAIPHPLGNPALPADEEKALRRKLVEKAL
HHHHHCCCCEEEHEEEEEHHHHCCCCCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHH
KALTTEVEGQTVFD
HHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA