Click here to switch to the map view.

The map label for this gene is acpS

Identifier: 78044717

GI number: 78044717

Start: 576289

End: 576660

Strand: Direct

Name: acpS

Synonym: CHY_0664

Alternate gene names: 78044717

Gene position: 576289-576660 (Clockwise)

Preceding gene: 78043285

Following gene: 78043971

Centisome position: 24.0

GC content: 38.98

Gene sequence:

>372_bases
GTGTACAGCTCGGGAATTGATATAGTTGATGTTTTAAGGATAAAAAAACTCCACGAGCGGTTTGGGGAGCGTTTTTTACA
TAAGATTTATACCAAAGGCGAGTTAGAGTATGCTTTTTCGACAAAAGAACCTTATTTGCGTTTAGCCGCCCGCTTTGCTG
CTAAAGAAGCAGCGGCTAAAGCTTTAGGTACCGGGATAGGAAAGGTAAATTTTAAAGATATTGAAGTAGTTTTGGGAACG
GATGGTCCTGAACTTATTTTTCATGGTTATGCGGCAAAAATTTTTCAGGAAAAAGGTTTTACGGGAAAAAGCTTAAGTTT
AAGCCATGAAAAAAAGGTAGCGGTAGCAATTTGCGTGATGTGGAGGGATTAA

Upstream 100 bases:

>100_bases
CGGTAAAGTATTGCCGGGAATTATTTTTTTTAGACAATTATCTTTGACTTACGGTAAAATATTAATAAAGAGAGATTAAA
AAAGTTAAGGGGTAGTTAAG

Downstream 100 bases:

>100_bases
AATGCTTCTTTTAACCGGGCGGGAGATGGCGGAGTTTGACCAGAAAGCGATTAATGAATACGGGATTCCGGGAATTGTTT
TAATGGAAAATGCGGCTTTA

Product: holo-(acyl-carrier-protein) synthase

Products: NA

Alternate protein names: Holo-ACP synthase; 4'-phosphopantetheinyl transferase AcpS

Number of amino acids: Translated: 123; Mature: 123

Protein sequence:

>123_residues
MYSSGIDIVDVLRIKKLHERFGERFLHKIYTKGELEYAFSTKEPYLRLAARFAAKEAAAKALGTGIGKVNFKDIEVVLGT
DGPELIFHGYAAKIFQEKGFTGKSLSLSHEKKVAVAICVMWRD

Sequences:

>Translated_123_residues
MYSSGIDIVDVLRIKKLHERFGERFLHKIYTKGELEYAFSTKEPYLRLAARFAAKEAAAKALGTGIGKVNFKDIEVVLGT
DGPELIFHGYAAKIFQEKGFTGKSLSLSHEKKVAVAICVMWRD
>Mature_123_residues
MYSSGIDIVDVLRIKKLHERFGERFLHKIYTKGELEYAFSTKEPYLRLAARFAAKEAAAKALGTGIGKVNFKDIEVVLGT
DGPELIFHGYAAKIFQEKGFTGKSLSLSHEKKVAVAICVMWRD

Specific function: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein

COG id: COG0736

COG function: function code I; Phosphopantetheinyl transferase (holo-ACP synthase)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the P-Pant transferase superfamily. AcpS family

Homologues:

Organism=Escherichia coli, GI1788916, Length=118, Percent_Identity=34.7457627118644, Blast_Score=62, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACPS_CARHZ (Q3AEB5)

Other databases:

- EMBL:   CP000141
- RefSeq:   YP_359519.1
- ProteinModelPortal:   Q3AEB5
- SMR:   Q3AEB5
- STRING:   Q3AEB5
- GeneID:   3727839
- GenomeReviews:   CP000141_GR
- KEGG:   chy:CHY_0664
- NMPDR:   fig|246194.3.peg.531
- TIGR:   CHY_0664
- eggNOG:   COG0736
- HOGENOM:   HBG734479
- OMA:   HIGTDII
- BioCyc:   CHYD246194:CHY_0664-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00101
- InterPro:   IPR008278
- InterPro:   IPR002582
- InterPro:   IPR004568
- ProDom:   PD004282
- TIGRFAMs:   TIGR00516
- TIGRFAMs:   TIGR00556

Pfam domain/function: PF01648 ACPS; SSF56214 4-PPT_transf

EC number: =2.7.8.7

Molecular weight: Translated: 13782; Mature: 13782

Theoretical pI: Translated: 9.83; Mature: 9.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYSSGIDIVDVLRIKKLHERFGERFLHKIYTKGELEYAFSTKEPYLRLAARFAAKEAAAK
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHH
ALGTGIGKVNFKDIEVVLGTDGPELIFHGYAAKIFQEKGFTGKSLSLSHEKKVAVAICVM
HHHCCCCCCCCEEEEEEECCCCCCEEEHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEE
WRD
ECC
>Mature Secondary Structure
MYSSGIDIVDVLRIKKLHERFGERFLHKIYTKGELEYAFSTKEPYLRLAARFAAKEAAAK
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHH
ALGTGIGKVNFKDIEVVLGTDGPELIFHGYAAKIFQEKGFTGKSLSLSHEKKVAVAICVM
HHHCCCCCCCCEEEEEEECCCCCCEEEHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEE
WRD
ECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA