| Definition | Carboxydothermus hydrogenoformans Z-2901 chromosome, complete genome. |
|---|---|
| Accession | NC_007503 |
| Length | 2,401,520 |
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The map label for this gene is uvrA [H]
Identifier: 78044591
GI number: 78044591
Start: 221829
End: 224651
Strand: Direct
Name: uvrA [H]
Synonym: CHY_0259
Alternate gene names: 78044591
Gene position: 221829-224651 (Clockwise)
Preceding gene: 78043646
Following gene: 78043707
Centisome position: 9.24
GC content: 48.25
Gene sequence:
>2823_bases ATGGATAAGATTGTCATTAAAGGGGCCAGGGTTCATAATCTAAAAAATATAGATTTAACCCTGCCGCGCAATAAATTTAT CGTTATTACCGGGGTTTCCGGTTCCGGCAAATCGTCGTTGGCCTTTGACACCATTTATGCCGAAGGACAGCGGCGGTATG TGGAAAGTTTATCGGCTTATGCCCGCCAGTTTTTGGGGCAAATGGATAAGCCCGATGTGGATTTTATCGAAGGGTTGTCA CCGGCAATTTCCATTGACCAGAAGACCACGTCCAAAAACCCCCGGTCAACGGTGGGTACGGTTACGGAGATTCACGATTA TTTAAGGCTTTTATATGCCCGCATAGGAATACCCCACTGCCCGGTTTGCGGGCGGGTGGTAGAAAAACAAACCATTGACC AGATGGTCGATAGATTATTAGCTTTACCCGAACGGACCAAATTGGTAATTATGGCGCCTATTGTGCGGGGAAGGAAGGGA GAGTTTGTCAAAACTTTGGAAGATATCCGGCGTCAGGGTTTTGCCCGGGTCCGGGTGGATGGTATTCTTTATGACTTAGC GGAAGATATTAAGTTAGAAAAAAATAAAAAACACAATATAGATGTTGTTGTTGACCGGCTGGTAGTAAAAGACGGAATAA AAACCAGGCTTTACGATTCCTTAGAAACGGCGCTTAAGCTTACCGAAGGCCTGGCCGTGGTGGAAGTAGTAGACGGGGAG GAGATTACTTTTTCCGAAAACTTTGCCTGTCCCCACTGTGAAATAAGCCTTCCGGAGATAAGCCCCCGGCTTTTTTCCTT TAATAATCCCTTTGGGGCTTGTCCCGAATGTACCGGCCTTGGTTATAAATTGGAAGTGGATCCGGATCTGGTAATACCCG ATAAAGATTTGACGTTACGGCAGGGGGCAATAGCCGCCTGGAACGCGGGTAATATGCAGGCATATTATTTTCAGGTGTTA GAGGCTTTAGCGAAAAAATACCGGTTTAGTTTGGACGTGCCGGTAAAAGAGCTTGAGCCGGAAATTTTAAGAATAATCCT CTATGGCCTTCCTGGGGAGAAAGTGCGGGTCAGGTATTACAACTATACCAATGGCAATTCTTACACCTTTGATGCCAACT GGGAGGGGGTTATCCCCAATTTAGAGCGGCGGTACCGGGAAACCCAGTCGGAGGCGGTGCGGGAAGAAATTGAAAAATTT ATGACCCAGAGAAAATGTCCCTCCTGCCAGGGAGCCCGGCTGAAAAAAGAAGCCCTGGCGGTAACGGTGGGCGGAAAAAA CATTCATGAACTTGGCGAAATGACCGTGGAAAAGCTTCTGGCTTTCCTGGAAAATCTTGAGTTAACGGAACGAGAGTTTT TAATTGCCCGGCAGGTTTTGAAGGAAATTAAGGAACGCCTGGGGTTTTTAAACAACGTGGGTTTGGATTACCTGACCTTA AATCGCTCCGCTACTACCTTGTCCGGCGGGGAAGCTCAGCGGATCCGCCTTGCTACGCAAATCGGTTCCGGCCTTACCGG GGTGCTGTATGTTTTGGATGAACCATCAATAGGCTTGCATCCCCGGGATACCAAGCGGCTTTTGGATACTTTAAAGCGAC TGCGGGATCTGGGCAATACTTTAATAGTGGTGGAACACGATGAAGAGACCATTAGGGAAGCGGATTTTATTGTGGACATG GGACCGGGAGCTGGCGAAAAAGGAGGGCAGGTAGTAGCTGCAGGTACCCTGGAAGAAGTGCTAAAGCATCCCGATTCAAT TACTGCAAAATATCTCAGGGGGGAAGAAAAAATCCCCGTGCCGCTTTTTCGCCGGAGCGGTAATGGTAAAACTATTACCA TTGTGGGGGCCCGGGAAAACAATTTAAAAAATATTACCGTCGAAATTCCCCTGGGGAAATTTGTAGCGGTAACCGGGGTG TCCGGTTCCGGTAAAAGTACGTTAATTAATGAAATTTTGTATAAGGCTGTGGCCGGAAAGTTTTATAAGCTAAAAGAAAA ACCCGGAGCTCATGATGAGATTTTAGGTCTTACTTACATTGATAAGATAATCAATATCGACCAGTCGCCCATCGGCCGAA CACCGCGCTCAAATCCGGCAACCTATACCGGAGTGTTTAACGATATCCGCGAGCTTTTTGCGGCAACTCCCGAAGCCCGG ATGCGGGGTTATAAACCGGGACGGTTTTCTTTTAACGTGAAGGGCGGACGGTGTGAAGCATGTGAAGGGGACGGGATAAT CAAGATTGAAATGCATTTTCTCCCCGATGTTTACGTCCCCTGCGAGGTGTGTAAGGGGGCCCGGTATAACCGGGAAACGT TGGAGGTGCGGTATAAAGGAAAAAATATTGCCGAGGTACTGGATATGACGGTAGAGGAGGCTCTGGAGTTTTTCTCCGCG ATACCCAGAATCCAGCGCAAACTGCAAACCCTTTATGATGTGGGCTTAGGCTATATCCGCCTGGGGCAGCCGGCTACTAC CCTATCCGGCGGCGAAGCTCAGAGGGTAAAGCTGGCCACCGAACTTTCCCGGCGTTCCACCGGGAAAACTTTATACATTT TAGATGAGCCCACTACGGGCCTGCACATTGCCGATGTGCATAGGCTTCTTGATGTTTTAAACCGCCTGGTGGAAGCGGGA AATACGGTGGTGGTAATCGAACACAATTTAGATGTAATTAAGACTGCCGACTGGATAATCGATTTGGGACCCGAAGGAGG CGATAAAGGCGGGCAGGTAGTGGCCGAGGGAACTCCAGAGGAAGTGGCCCGGAATCCAGCCTCTTATACCGGAAAGTTTT TAAGGCCGTATCTTAATTTATAA
Upstream 100 bases:
>100_bases AGCTTTGGAGTTTGAAAAAGCGGCGATGCTGCGCGACTTAATAATTGAGCTTCGGGCGCAAAAGGCGGTCAAAAAGTAAT AATGGAGGTTTTACACACTG
Downstream 100 bases:
>100_bases AAAAGCCCCTGGTTTTTACCAGGGGCTTTTTAGTGCTATTGTTTGGGGATTTGCTTGAGATACTCTTCTGCTTTGTTCAA AAGGAGTTCAGTTAAAGCGG
Product: excinuclease ABC subunit A
Products: NA
Alternate protein names: UvrA protein; Excinuclease ABC subunit A [H]
Number of amino acids: Translated: 940; Mature: 940
Protein sequence:
>940_residues MDKIVIKGARVHNLKNIDLTLPRNKFIVITGVSGSGKSSLAFDTIYAEGQRRYVESLSAYARQFLGQMDKPDVDFIEGLS PAISIDQKTTSKNPRSTVGTVTEIHDYLRLLYARIGIPHCPVCGRVVEKQTIDQMVDRLLALPERTKLVIMAPIVRGRKG EFVKTLEDIRRQGFARVRVDGILYDLAEDIKLEKNKKHNIDVVVDRLVVKDGIKTRLYDSLETALKLTEGLAVVEVVDGE EITFSENFACPHCEISLPEISPRLFSFNNPFGACPECTGLGYKLEVDPDLVIPDKDLTLRQGAIAAWNAGNMQAYYFQVL EALAKKYRFSLDVPVKELEPEILRIILYGLPGEKVRVRYYNYTNGNSYTFDANWEGVIPNLERRYRETQSEAVREEIEKF MTQRKCPSCQGARLKKEALAVTVGGKNIHELGEMTVEKLLAFLENLELTEREFLIARQVLKEIKERLGFLNNVGLDYLTL NRSATTLSGGEAQRIRLATQIGSGLTGVLYVLDEPSIGLHPRDTKRLLDTLKRLRDLGNTLIVVEHDEETIREADFIVDM GPGAGEKGGQVVAAGTLEEVLKHPDSITAKYLRGEEKIPVPLFRRSGNGKTITIVGARENNLKNITVEIPLGKFVAVTGV SGSGKSTLINEILYKAVAGKFYKLKEKPGAHDEILGLTYIDKIINIDQSPIGRTPRSNPATYTGVFNDIRELFAATPEAR MRGYKPGRFSFNVKGGRCEACEGDGIIKIEMHFLPDVYVPCEVCKGARYNRETLEVRYKGKNIAEVLDMTVEEALEFFSA IPRIQRKLQTLYDVGLGYIRLGQPATTLSGGEAQRVKLATELSRRSTGKTLYILDEPTTGLHIADVHRLLDVLNRLVEAG NTVVVIEHNLDVIKTADWIIDLGPEGGDKGGQVVAEGTPEEVARNPASYTGKFLRPYLNL
Sequences:
>Translated_940_residues MDKIVIKGARVHNLKNIDLTLPRNKFIVITGVSGSGKSSLAFDTIYAEGQRRYVESLSAYARQFLGQMDKPDVDFIEGLS PAISIDQKTTSKNPRSTVGTVTEIHDYLRLLYARIGIPHCPVCGRVVEKQTIDQMVDRLLALPERTKLVIMAPIVRGRKG EFVKTLEDIRRQGFARVRVDGILYDLAEDIKLEKNKKHNIDVVVDRLVVKDGIKTRLYDSLETALKLTEGLAVVEVVDGE EITFSENFACPHCEISLPEISPRLFSFNNPFGACPECTGLGYKLEVDPDLVIPDKDLTLRQGAIAAWNAGNMQAYYFQVL EALAKKYRFSLDVPVKELEPEILRIILYGLPGEKVRVRYYNYTNGNSYTFDANWEGVIPNLERRYRETQSEAVREEIEKF MTQRKCPSCQGARLKKEALAVTVGGKNIHELGEMTVEKLLAFLENLELTEREFLIARQVLKEIKERLGFLNNVGLDYLTL NRSATTLSGGEAQRIRLATQIGSGLTGVLYVLDEPSIGLHPRDTKRLLDTLKRLRDLGNTLIVVEHDEETIREADFIVDM GPGAGEKGGQVVAAGTLEEVLKHPDSITAKYLRGEEKIPVPLFRRSGNGKTITIVGARENNLKNITVEIPLGKFVAVTGV SGSGKSTLINEILYKAVAGKFYKLKEKPGAHDEILGLTYIDKIINIDQSPIGRTPRSNPATYTGVFNDIRELFAATPEAR MRGYKPGRFSFNVKGGRCEACEGDGIIKIEMHFLPDVYVPCEVCKGARYNRETLEVRYKGKNIAEVLDMTVEEALEFFSA IPRIQRKLQTLYDVGLGYIRLGQPATTLSGGEAQRVKLATELSRRSTGKTLYILDEPTTGLHIADVHRLLDVLNRLVEAG NTVVVIEHNLDVIKTADWIIDLGPEGGDKGGQVVAEGTPEEVARNPASYTGKFLRPYLNL >Mature_940_residues MDKIVIKGARVHNLKNIDLTLPRNKFIVITGVSGSGKSSLAFDTIYAEGQRRYVESLSAYARQFLGQMDKPDVDFIEGLS PAISIDQKTTSKNPRSTVGTVTEIHDYLRLLYARIGIPHCPVCGRVVEKQTIDQMVDRLLALPERTKLVIMAPIVRGRKG EFVKTLEDIRRQGFARVRVDGILYDLAEDIKLEKNKKHNIDVVVDRLVVKDGIKTRLYDSLETALKLTEGLAVVEVVDGE EITFSENFACPHCEISLPEISPRLFSFNNPFGACPECTGLGYKLEVDPDLVIPDKDLTLRQGAIAAWNAGNMQAYYFQVL EALAKKYRFSLDVPVKELEPEILRIILYGLPGEKVRVRYYNYTNGNSYTFDANWEGVIPNLERRYRETQSEAVREEIEKF MTQRKCPSCQGARLKKEALAVTVGGKNIHELGEMTVEKLLAFLENLELTEREFLIARQVLKEIKERLGFLNNVGLDYLTL NRSATTLSGGEAQRIRLATQIGSGLTGVLYVLDEPSIGLHPRDTKRLLDTLKRLRDLGNTLIVVEHDEETIREADFIVDM GPGAGEKGGQVVAAGTLEEVLKHPDSITAKYLRGEEKIPVPLFRRSGNGKTITIVGARENNLKNITVEIPLGKFVAVTGV SGSGKSTLINEILYKAVAGKFYKLKEKPGAHDEILGLTYIDKIINIDQSPIGRTPRSNPATYTGVFNDIRELFAATPEAR MRGYKPGRFSFNVKGGRCEACEGDGIIKIEMHFLPDVYVPCEVCKGARYNRETLEVRYKGKNIAEVLDMTVEEALEFFSA IPRIQRKLQTLYDVGLGYIRLGQPATTLSGGEAQRVKLATELSRRSTGKTLYILDEPTTGLHIADVHRLLDVLNRLVEAG NTVVVIEHNLDVIKTADWIIDLGPEGGDKGGQVVAEGTPEEVARNPASYTGKFLRPYLNL
Specific function: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion h
COG id: COG0178
COG function: function code L; Excinuclease ATPase subunit
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 2 ABC transporter domains [H]
Homologues:
Organism=Escherichia coli, GI2367343, Length=943, Percent_Identity=60.763520678685, Blast_Score=1150, Evalue=0.0,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003439 - InterPro: IPR017871 - InterPro: IPR013815 - InterPro: IPR003593 - InterPro: IPR004602 [H]
Pfam domain/function: PF00005 ABC_tran [H]
EC number: NA
Molecular weight: Translated: 104739; Mature: 104739
Theoretical pI: Translated: 7.33; Mature: 7.33
Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.3 %Cys (Translated Protein) 1.2 %Met (Translated Protein) 2.4 %Cys+Met (Translated Protein) 1.3 %Cys (Mature Protein) 1.2 %Met (Mature Protein) 2.4 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MDKIVIKGARVHNLKNIDLTLPRNKFIVITGVSGSGKSSLAFDTIYAEGQRRYVESLSAY CCCEEEECCEECCCCCEEEEECCCCEEEEEECCCCCCCCEEEHHHHHHHHHHHHHHHHHH ARQFLGQMDKPDVDFIEGLSPAISIDQKTTSKNPRSTVGTVTEIHDYLRLLYARIGIPHC HHHHHCCCCCCCHHHHHCCCCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCC PVCGRVVEKQTIDQMVDRLLALPERTKLVIMAPIVRGRKGEFVKTLEDIRRQGFARVRVD CHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHCCCEEEEEH GILYDLAEDIKLEKNKKHNIDVVVDRLVVKDGIKTRLYDSLETALKLTEGLAVVEVVDGE HHHHHHHHHHEECCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCEEEEEEECCC EITFSENFACPHCEISLPEISPRLFSFNNPFGACPECTGLGYKLEVDPDLVIPDKDLTLR EEEEECCCCCCCCEEECCCCCCHHEECCCCCCCCCCCCCCCEEEECCCCEEECCCCCEEE QGAIAAWNAGNMQAYYFQVLEALAKKYRFSLDVPVKELEPEILRIILYGLPGEKVRVRYY CCCEEEECCCCCHHHHHHHHHHHHHHHCEECCCCHHHHCHHHHHHEEECCCCCEEEEEEE NYTNGNSYTFDANWEGVIPNLERRYRETQSEAVREEIEKFMTQRKCPSCQGARLKKEALA EECCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEECEEEE VTVGGKNIHELGEMTVEKLLAFLENLELTEREFLIARQVLKEIKERLGFLNNVGLDYLTL EEECCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCHHHCCCCEEEEE NRSATTLSGGEAQRIRLATQIGSGLTGVLYVLDEPSIGLHPRDTKRLLDTLKRLRDLGNT CCCCCCCCCCCCHHEEEEHHHCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCE LIVVEHDEETIREADFIVDMGPGAGEKGGQVVAAGTLEEVLKHPDSITAKYLRGEEKIPV EEEEECCHHHHHHCCEEEECCCCCCCCCCEEEECCCHHHHHHCCCHHHHHHHCCCCCCCC PLFRRSGNGKTITIVGARENNLKNITVEIPLGKFVAVTGVSGSGKSTLINEILYKAVAGK HHEEECCCCCEEEEEECCCCCCEEEEEEECCCCEEEEEECCCCCHHHHHHHHHHHHHHCC FYKLKEKPGAHDEILGLTYIDKIINIDQSPIGRTPRSNPATYTGVFNDIRELFAATPEAR CEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHCCCHHH MRGYKPGRFSFNVKGGRCEACEGDGIIKIEMHFLPDVYVPCEVCKGARYNRETLEVRYKG HCCCCCCCEEEEECCCEECCCCCCCEEEEEEEECCCCCCCHHHHCCCCCCCCEEEEEECC KNIAEVLDMTVEEALEFFSAIPRIQRKLQTLYDVGLGYIRLGQPATTLSGGEAQRVKLAT CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCHHHHHHH ELSRRSTGKTLYILDEPTTGLHIADVHRLLDVLNRLVEAGNTVVVIEHNLDVIKTADWII HHHHCCCCCEEEEEECCCCCEEHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEECCEEE DLGPEGGDKGGQVVAEGTPEEVARNPASYTGKFLRPYLNL EECCCCCCCCCEEEECCCHHHHHCCCHHHHHHHHHHHHCC >Mature Secondary Structure MDKIVIKGARVHNLKNIDLTLPRNKFIVITGVSGSGKSSLAFDTIYAEGQRRYVESLSAY CCCEEEECCEECCCCCEEEEECCCCEEEEEECCCCCCCCEEEHHHHHHHHHHHHHHHHHH ARQFLGQMDKPDVDFIEGLSPAISIDQKTTSKNPRSTVGTVTEIHDYLRLLYARIGIPHC HHHHHCCCCCCCHHHHHCCCCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCC PVCGRVVEKQTIDQMVDRLLALPERTKLVIMAPIVRGRKGEFVKTLEDIRRQGFARVRVD CHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHCCCEEEEEH GILYDLAEDIKLEKNKKHNIDVVVDRLVVKDGIKTRLYDSLETALKLTEGLAVVEVVDGE HHHHHHHHHHEECCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCEEEEEEECCC EITFSENFACPHCEISLPEISPRLFSFNNPFGACPECTGLGYKLEVDPDLVIPDKDLTLR EEEEECCCCCCCCEEECCCCCCHHEECCCCCCCCCCCCCCCEEEECCCCEEECCCCCEEE QGAIAAWNAGNMQAYYFQVLEALAKKYRFSLDVPVKELEPEILRIILYGLPGEKVRVRYY CCCEEEECCCCCHHHHHHHHHHHHHHHCEECCCCHHHHCHHHHHHEEECCCCCEEEEEEE NYTNGNSYTFDANWEGVIPNLERRYRETQSEAVREEIEKFMTQRKCPSCQGARLKKEALA EECCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEECEEEE VTVGGKNIHELGEMTVEKLLAFLENLELTEREFLIARQVLKEIKERLGFLNNVGLDYLTL EEECCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCHHHCCCCEEEEE NRSATTLSGGEAQRIRLATQIGSGLTGVLYVLDEPSIGLHPRDTKRLLDTLKRLRDLGNT CCCCCCCCCCCCHHEEEEHHHCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCE LIVVEHDEETIREADFIVDMGPGAGEKGGQVVAAGTLEEVLKHPDSITAKYLRGEEKIPV EEEEECCHHHHHHCCEEEECCCCCCCCCCEEEECCCHHHHHHCCCHHHHHHHCCCCCCCC PLFRRSGNGKTITIVGARENNLKNITVEIPLGKFVAVTGVSGSGKSTLINEILYKAVAGK HHEEECCCCCEEEEEECCCCCCEEEEEEECCCCEEEEEECCCCCHHHHHHHHHHHHHHCC FYKLKEKPGAHDEILGLTYIDKIINIDQSPIGRTPRSNPATYTGVFNDIRELFAATPEAR CEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHCCCHHH MRGYKPGRFSFNVKGGRCEACEGDGIIKIEMHFLPDVYVPCEVCKGARYNRETLEVRYKG HCCCCCCCEEEEECCCEECCCCCCCEEEEEEEECCCCCCCHHHHCCCCCCCCEEEEEECC KNIAEVLDMTVEEALEFFSAIPRIQRKLQTLYDVGLGYIRLGQPATTLSGGEAQRVKLAT CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCHHHHHHH ELSRRSTGKTLYILDEPTTGLHIADVHRLLDVLNRLVEAGNTVVVIEHNLDVIKTADWII HHHHCCCCCEEEEEECCCCCEEHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEECCEEE DLGPEGGDKGGQVVAEGTPEEVARNPASYTGKFLRPYLNL EECCCCCCCCCEEEECCCHHHHHCCCHHHHHHHHHHHHCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: DNA [C]
Specific reaction: Protein + DNA = Protein-DNA [C]
General reaction: Hydrolase; Acting on ester bonds [C]
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 11058132 [H]