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The map label for this gene is yyxA [H]

Identifier: 78044578

GI number: 78044578

Start: 46164

End: 47276

Strand: Direct

Name: yyxA [H]

Synonym: CHY_0057

Alternate gene names: 78044578

Gene position: 46164-47276 (Clockwise)

Preceding gene: 78043675

Following gene: 78045158

Centisome position: 1.92

GC content: 44.56

Gene sequence:

>1113_bases
ATGTACTATTATTACAGCAATCAGGATAAAAAACCGTCATTTTTAAGCTATGTCTTGGTTTCCCTAATTTCAGCTATTAT
CGGTGGCCTTTTAGTGGTAATGTTTGTACCAGGCCTGGTGAAAGGAAATGTATCAACTACCGGGACTATAGAGAAAAGGG
TTATTTATGAGGATAAAAGCCCGGTAGTTACGGTAGCCGAAGAAGTAGGGCCAGCGGTGGTGGGAATTTCCAACAAAGTA
ACATTTCAGGCCGGGGATGTACCTCATAATAATGTAGAACAGGCTACCGGTTCAGGAGTTATCATTGATGCCAGAGGTTA
CATTGTCACCAATGAGCATGTTATTCGCAATGCTACTGATTTAACGGTAACGCTGGCAAACGGAAAACAATTCCCGGCGA
AAATAGTGGGAAAGGATCCCCGAACGGACCTGGCGGTAATAAAAATTGATCCCGGCAACGAAAAGCTCACGGTTGCCCGC
TGGGGGGATTCGGATAAAATAAAAGTAGGGGAGCTGGCGGTAGCCATAGGAAACCCTTTAAGCCTTGATTTTGCGAGAAC
CGTTACTGCCGGTATAATTTCGGCGAAAAACCGTATTTTAAACATGGACGGCCAGCAGTACGAGCTGATTCAGACCGATG
CGGCGATAAACCCCGGAAACTCCGGCGGAGCCTTAGTAAATGCTGCCGGTGAAGTAATAGGCATTAACTCCATTAAAATT
TCCCTGTCGGGAGTTGAAGGTTTAGGCTTTGCCATTCCGAGCAATATCGCTAAGCCTATCGTTGAAGAGCTCATTAAAAA
CGGTAAGGTCATTCGCCCCTGGATGGGGATTGAAGGACAAACCATTGACGAAGAATTTGCTCAGTATAAGGGCTTAAAGC
AGAAAAGCGGTGTGTATGTAGCCCGGGTAGTAAAAGACGGACCGTCGGCGAAAGCAGGTTTAAAAGATAACGATATTATC
ATCGAATTTGACGGGGTAAAAATCGAGAAGTTTGAAGATTTAAGGAATGCCGTTTTAAAACACAAAGTCGGTGACGAAGT
AAAAGTGAAAGTATTGCGGGGCGATAAAGAAATGACCTTTAAAGTTAAACTTGGCGAAATGCCGGCGGAGTAA

Upstream 100 bases:

>100_bases
TTAAAAACTTCTCCACAAATCCTTAACAAATTTAAGCAGGAAATACCCCGCTTGAAGGCGAATTTATACCTCAAAATAAA
AAAAAGCGGGGTTGTGTGGT

Downstream 100 bases:

>100_bases
GGGATGGTACCGGCAACCTGTGACTTTTGCGACCTTATACCCGTTTATCTGGTGGTGTAAATGGAAATTACAATTGTTGC
GGTTGGCAAAATCAAAGAAA

Product: putative serine protease Do

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 370; Mature: 370

Protein sequence:

>370_residues
MYYYYSNQDKKPSFLSYVLVSLISAIIGGLLVVMFVPGLVKGNVSTTGTIEKRVIYEDKSPVVTVAEEVGPAVVGISNKV
TFQAGDVPHNNVEQATGSGVIIDARGYIVTNEHVIRNATDLTVTLANGKQFPAKIVGKDPRTDLAVIKIDPGNEKLTVAR
WGDSDKIKVGELAVAIGNPLSLDFARTVTAGIISAKNRILNMDGQQYELIQTDAAINPGNSGGALVNAAGEVIGINSIKI
SLSGVEGLGFAIPSNIAKPIVEELIKNGKVIRPWMGIEGQTIDEEFAQYKGLKQKSGVYVARVVKDGPSAKAGLKDNDII
IEFDGVKIEKFEDLRNAVLKHKVGDEVKVKVLRGDKEMTFKVKLGEMPAE

Sequences:

>Translated_370_residues
MYYYYSNQDKKPSFLSYVLVSLISAIIGGLLVVMFVPGLVKGNVSTTGTIEKRVIYEDKSPVVTVAEEVGPAVVGISNKV
TFQAGDVPHNNVEQATGSGVIIDARGYIVTNEHVIRNATDLTVTLANGKQFPAKIVGKDPRTDLAVIKIDPGNEKLTVAR
WGDSDKIKVGELAVAIGNPLSLDFARTVTAGIISAKNRILNMDGQQYELIQTDAAINPGNSGGALVNAAGEVIGINSIKI
SLSGVEGLGFAIPSNIAKPIVEELIKNGKVIRPWMGIEGQTIDEEFAQYKGLKQKSGVYVARVVKDGPSAKAGLKDNDII
IEFDGVKIEKFEDLRNAVLKHKVGDEVKVKVLRGDKEMTFKVKLGEMPAE
>Mature_370_residues
MYYYYSNQDKKPSFLSYVLVSLISAIIGGLLVVMFVPGLVKGNVSTTGTIEKRVIYEDKSPVVTVAEEVGPAVVGISNKV
TFQAGDVPHNNVEQATGSGVIIDARGYIVTNEHVIRNATDLTVTLANGKQFPAKIVGKDPRTDLAVIKIDPGNEKLTVAR
WGDSDKIKVGELAVAIGNPLSLDFARTVTAGIISAKNRILNMDGQQYELIQTDAAINPGNSGGALVNAAGEVIGINSIKI
SLSGVEGLGFAIPSNIAKPIVEELIKNGKVIRPWMGIEGQTIDEEFAQYKGLKQKSGVYVARVVKDGPSAKAGLKDNDII
IEFDGVKIEKFEDLRNAVLKHKVGDEVKVKVLRGDKEMTFKVKLGEMPAE

Specific function: Serine Protease That Is Required At High Temperature. Involved In The Degradation Of Damaged Proteins. It Can Degrade Icia, Ada, Casein And Globin. Shared Specificity With Degq. [C]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Homo sapiens, GI24308541, Length=337, Percent_Identity=34.4213649851632, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI4506141, Length=319, Percent_Identity=37.6175548589342, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI22129776, Length=320, Percent_Identity=36.25, Blast_Score=154, Evalue=1e-37,
Organism=Homo sapiens, GI7019477, Length=322, Percent_Identity=31.9875776397516, Blast_Score=132, Evalue=4e-31,
Organism=Escherichia coli, GI1786356, Length=276, Percent_Identity=44.9275362318841, Blast_Score=213, Evalue=1e-56,
Organism=Escherichia coli, GI1789630, Length=365, Percent_Identity=39.1780821917808, Blast_Score=207, Evalue=9e-55,
Organism=Escherichia coli, GI1789629, Length=328, Percent_Identity=39.0243902439024, Blast_Score=203, Evalue=1e-53,
Organism=Drosophila melanogaster, GI24646839, Length=365, Percent_Identity=32.3287671232877, Blast_Score=144, Evalue=1e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 39702; Mature: 39702

Theoretical pI: Translated: 7.71; Mature: 7.71

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYYYYSNQDKKPSFLSYVLVSLISAIIGGLLVVMFVPGLVKGNVSTTGTIEKRVIYEDKS
CEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCEEEEEEEECCC
PVVTVAEEVGPAVVGISNKVTFQAGDVPHNNVEQATGSGVIIDARGYIVTNEHVIRNATD
CEEEEHHHCCCEEEECCCEEEEEECCCCCCCHHHCCCCEEEEECCCEEEECCCEEECCCE
LTVTLANGKQFPAKIVGKDPRTDLAVIKIDPGNEKLTVARWGDSDKIKVGELAVAIGNPL
EEEEEECCCCCCCEECCCCCCCCEEEEEECCCCCEEEEEEECCCCCEEEEEEEEEECCCC
SLDFARTVTAGIISAKNRILNMDGQQYELIQTDAAINPGNSGGALVNAAGEVIGINSIKI
CCHHHHHHHHHHHHHCCEEECCCCCEEEEEEECCCCCCCCCCCEEEECCCCEEEEEEEEE
SLSGVEGLGFAIPSNIAKPIVEELIKNGKVIRPWMGIEGQTIDEEFAQYKGLKQKSGVYV
EEECCCCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHCCCCCCCCEEE
ARVVKDGPSAKAGLKDNDIIIEFDGVKIEKFEDLRNAVLKHKVGDEVKVKVLRGDKEMTF
EEEEECCCCCCCCCCCCCEEEEECCEEEHHHHHHHHHHHHHCCCCCEEEEEEECCCEEEE
KVKLGEMPAE
EEEECCCCCC
>Mature Secondary Structure
MYYYYSNQDKKPSFLSYVLVSLISAIIGGLLVVMFVPGLVKGNVSTTGTIEKRVIYEDKS
CEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCEEEEEEEECCC
PVVTVAEEVGPAVVGISNKVTFQAGDVPHNNVEQATGSGVIIDARGYIVTNEHVIRNATD
CEEEEHHHCCCEEEECCCEEEEEECCCCCCCHHHCCCCEEEEECCCEEEECCCEEECCCE
LTVTLANGKQFPAKIVGKDPRTDLAVIKIDPGNEKLTVARWGDSDKIKVGELAVAIGNPL
EEEEEECCCCCCCEECCCCCCCCEEEEEECCCCCEEEEEEECCCCCEEEEEEEEEECCCC
SLDFARTVTAGIISAKNRILNMDGQQYELIQTDAAINPGNSGGALVNAAGEVIGINSIKI
CCHHHHHHHHHHHHHCCEEECCCCCEEEEEEECCCCCCCCCCCEEEECCCCEEEEEEEEE
SLSGVEGLGFAIPSNIAKPIVEELIKNGKVIRPWMGIEGQTIDEEFAQYKGLKQKSGVYV
EEECCCCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHCCCCCCCCEEE
ARVVKDGPSAKAGLKDNDIIIEFDGVKIEKFEDLRNAVLKHKVGDEVKVKVLRGDKEMTF
EEEEECCCCCCCCCCCCCEEEEECCEEEHHHHHHHHHHHHHCCCCCEEEEEEECCCEEEE
KVKLGEMPAE
EEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Serine endopeptidases [C]

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377; 8113162 [H]