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The map label for this gene is ttdA [C]

Identifier: 78044230

GI number: 78044230

Start: 50977

End: 51822

Strand: Direct

Name: ttdA [C]

Synonym: CHY_0061

Alternate gene names: 78044230

Gene position: 50977-51822 (Clockwise)

Preceding gene: 78043316

Following gene: 78043076

Centisome position: 2.12

GC content: 39.36

Gene sequence:

>846_bases
ATGCGTATCATTGAAGCAGCTCAAATTACGGAAGCTGTTGCTCAGCTTGCAATTAAAGCTAATTATTATTTAAATCCTGA
CCTGTATGAAGCGCTGGTTAAAGGTCGGGAAATGGAAGAATCGCCAATAGGTAAAGAGATTTTTGAAATATTGATAAAAA
ATGCTGAAATTGCTAGGGAAGAGGAAATGGCAATTTGTCAAGATACTGGCATGGCAGTTGTGTTTATGGAAATTGGCCAA
GATGTTCATATAGTAGGGGGAAATCTTGAGGACGCCGTTAATGCAGGTGTGGCAAAGGGGTATTTAGAAGGGTATTTACG
AAAATCTGTCGTAGAGGAGCCATTATTTAACCGAGTTAACACTAAGAATAACACTCCAGCTGTAATTCATGTGTCAATTG
TTCCTGGTGACAAAGTTAAAATAGTGCTTGCTCCTAAAGGTTTTGGTAGTGAGAATATGAGCGCACTTAGAATGTTTAAA
CCGTCTGATGGTATTGAAGCTATTAAGAAGTTTGTTGTTGATACTGTAGTCAATGCTGGTTCAAATCCTTGTCCACCTAT
AGTAATTGGAATAGGAATTGGCGGTACAATGGAAAAAGCTGCTCTTTTAGCGAAAAAAGCCTTGATTCGTCCGCTTAATA
TACGGAATTCTCATCCACAGTATGCTGCTTTAGAGCAAGAATTACTTGAATTAGTGAATAACACTGGTATTGGACCTCAG
GGGTTAGGTGGACGGATAACAGCATTGGCAGTAAATATTGAGTGGTTCCCAACCCACATTGCAGGTTTGCCAGTGGCAAT
TAATATAAATTGTCACGCCACCAGGCATGCTGAAATCGAACTTTAA

Upstream 100 bases:

>100_bases
TTACACCACTGGATCAGTTAGTTCACTGGTCCGGTGGTGTAAAAATTCTCATAAATGTGTTTTTTACTTCTAAATTTGGA
AAAAGGAAAGGGGTAAGAGG

Downstream 100 bases:

>100_bases
AGACTCTATAAGGGGGAAAAAAGATGAAAGAGCCTATCCGTATTACACTTCCTTTAACTGAAGAAAAGGTGCGTAGTCTT
AAAGCAGGTGATAGTGTCTT

Product: fumarate hydratase

Products: NA

Alternate protein names: Fumarase [H]

Number of amino acids: Translated: 281; Mature: 281

Protein sequence:

>281_residues
MRIIEAAQITEAVAQLAIKANYYLNPDLYEALVKGREMEESPIGKEIFEILIKNAEIAREEEMAICQDTGMAVVFMEIGQ
DVHIVGGNLEDAVNAGVAKGYLEGYLRKSVVEEPLFNRVNTKNNTPAVIHVSIVPGDKVKIVLAPKGFGSENMSALRMFK
PSDGIEAIKKFVVDTVVNAGSNPCPPIVIGIGIGGTMEKAALLAKKALIRPLNIRNSHPQYAALEQELLELVNNTGIGPQ
GLGGRITALAVNIEWFPTHIAGLPVAININCHATRHAEIEL

Sequences:

>Translated_281_residues
MRIIEAAQITEAVAQLAIKANYYLNPDLYEALVKGREMEESPIGKEIFEILIKNAEIAREEEMAICQDTGMAVVFMEIGQ
DVHIVGGNLEDAVNAGVAKGYLEGYLRKSVVEEPLFNRVNTKNNTPAVIHVSIVPGDKVKIVLAPKGFGSENMSALRMFK
PSDGIEAIKKFVVDTVVNAGSNPCPPIVIGIGIGGTMEKAALLAKKALIRPLNIRNSHPQYAALEQELLELVNNTGIGPQ
GLGGRITALAVNIEWFPTHIAGLPVAININCHATRHAEIEL
>Mature_281_residues
MRIIEAAQITEAVAQLAIKANYYLNPDLYEALVKGREMEESPIGKEIFEILIKNAEIAREEEMAICQDTGMAVVFMEIGQ
DVHIVGGNLEDAVNAGVAKGYLEGYLRKSVVEEPLFNRVNTKNNTPAVIHVSIVPGDKVKIVLAPKGFGSENMSALRMFK
PSDGIEAIKKFVVDTVVNAGSNPCPPIVIGIGIGGTMEKAALLAKKALIRPLNIRNSHPQYAALEQELLELVNNTGIGPQ
GLGGRITALAVNIEWFPTHIAGLPVAININCHATRHAEIEL

Specific function: Unknown

COG id: COG1951

COG function: function code C; Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I fumarase family [H]

Homologues:

Organism=Escherichia coli, GI1789442, Length=276, Percent_Identity=31.5217391304348, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI1790564, Length=240, Percent_Identity=33.75, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1787897, Length=256, Percent_Identity=33.203125, Blast_Score=103, Evalue=9e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004646 [H]

Pfam domain/function: PF05681 Fumerase [H]

EC number: =4.2.1.2 [H]

Molecular weight: Translated: 30350; Mature: 30350

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIIEAAQITEAVAQLAIKANYYLNPDLYEALVKGREMEESPIGKEIFEILIKNAEIARE
CCCCHHHHHHHHHHHHHHHCCEEECHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCHHHHH
EEMAICQDTGMAVVFMEIGQDVHIVGGNLEDAVNAGVAKGYLEGYLRKSVVEEPLFNRVN
HHHHHCCCCCCEEEEEECCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
TKNNTPAVIHVSIVPGDKVKIVLAPKGFGSENMSALRMFKPSDGIEAIKKFVVDTVVNAG
CCCCCCEEEEEEEECCCEEEEEEECCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHCC
SNPCPPIVIGIGIGGTMEKAALLAKKALIRPLNIRNSHPQYAALEQELLELVNNTGIGPQ
CCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCC
GLGGRITALAVNIEWFPTHIAGLPVAININCHATRHAEIEL
CCCCEEEEEEEEEEEECHHHCCCCEEEEEEEEEECEEEECC
>Mature Secondary Structure
MRIIEAAQITEAVAQLAIKANYYLNPDLYEALVKGREMEESPIGKEIFEILIKNAEIARE
CCCCHHHHHHHHHHHHHHHCCEEECHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCHHHHH
EEMAICQDTGMAVVFMEIGQDVHIVGGNLEDAVNAGVAKGYLEGYLRKSVVEEPLFNRVN
HHHHHCCCCCCEEEEEECCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
TKNNTPAVIHVSIVPGDKVKIVLAPKGFGSENMSALRMFKPSDGIEAIKKFVVDTVVNAG
CCCCCCEEEEEEEECCCEEEEEEECCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHCC
SNPCPPIVIGIGIGGTMEKAALLAKKALIRPLNIRNSHPQYAALEQELLELVNNTGIGPQ
CCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCC
GLGGRITALAVNIEWFPTHIAGLPVAININCHATRHAEIEL
CCCCEEEEEEEEEEEECHHHCCCCEEEEEEEEEECEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]