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The map label for this gene is cbiG [H]

Identifier: 78044220

GI number: 78044220

Start: 671728

End: 672738

Strand: Direct

Name: cbiG [H]

Synonym: CHY_0763

Alternate gene names: 78044220

Gene position: 671728-672738 (Clockwise)

Preceding gene: 78044806

Following gene: 78042730

Centisome position: 27.97

GC content: 43.72

Gene sequence:

>1011_bases
GTGATTAAGAATTTAATAATTTTTTACTTTACCGCAGCCGGCGAAACTCTGGCCCGGCGCTTTTTAACCCTAAAGCTTGG
GGGGAACGTTACTCTCTTTTCCGGTAAAAGCGCGGAAATTAAAAACTGTCTTAAAAAAAACTGGAACAACGATACAGCTT
TTCTTTTTATCGGAGCCTTAGGAATTGCGGTTCGCTTAATTGCTCCGTTTATCAAAGATAAGTTTTCCGACCCGGCGGTA
GTTGTAGCCGATGAAACGGGTAAATATTTTATAAGCGTTTTATCCGGCCATTTTGGTGGGGCAAATGAAATTTGTCAACT
TTTAGCCCAAAAGCTGGGGGGAGAAGCGGTAATTACCACCGCCACCGATGTTCAGGGAAAAGTTGGCTTGGATGTTTTAG
CCAGAAAATACGTGTTAAGGTATGCTGACCGGGAAGTTTTTAAAAGGGTAAATGCTGCCTTAGCCCGGGGAGAAGAGGTT
AAGTTTTTTGCCAGATCTTTGCCTTCCGATTTTCCCTATCCTTACCTGGCAGAAATTGAAGAGGAGTTTTCTGGCATTAA
AGTATTGATTTCGCCGTATCTTATTGCTCTAAAACCCAATGAATACCAGCTCTATCCTCCGGCGGTTTGGGTGGGTATAG
GCTGTCGCCGGGGAGTAGAGTTTACCCTGCTGGAAAAGGCAGTTCTCGAAGCTCTACAAGAGGGCGGTGTTTCTTTAAAA
GGTGTTGCCGGAATAGCCAGTATCGATCTTAAAAAAGATGAGACTGCTCTCCTGGAGCTGGCAGCGAAATACGGGCTTAA
AACAAAATTTTTTACGCGGGAGGAACTTTTGGAAGTAATTAATAAAAAAAATTTACAACAATCTTCTAAAGTTTTAACAA
AAGTAGGGGTGGGAAATGTATGCGAAGCGGCGGCTATCAAAGCGGCAGGGATGGGGAATTTAATATTGCCCAAGAAGATT
TTTCCCAAAGTGTCAGTAGCTCTGGCGGAAGCCTTGCGGTGGTGGGAATAG

Upstream 100 bases:

>100_bases
AACAAAACCGCCCTTATCTTTGTAGGGGAGTTTTTAAATCCGCCCCCTACTCGCTCAAAATTATATGCTCCCGATTTTAC
TCATGGTGGGAGAAGAAAAG

Downstream 100 bases:

>100_bases
GACCGGGAGGAAAGGAAGAACTGACTCCTTTAGCCTTAAGTTACCTCCAGCAGTGTACGGTAATAATTGGTTATAAAACC
TATATTGATTTAGTTAAATC

Product: cobalamin biosynthesis protein CbiG

Products: S-adenosyl-L-homocysteine; Precorrin 5

Alternate protein names: NA

Number of amino acids: Translated: 336; Mature: 336

Protein sequence:

>336_residues
MIKNLIIFYFTAAGETLARRFLTLKLGGNVTLFSGKSAEIKNCLKKNWNNDTAFLFIGALGIAVRLIAPFIKDKFSDPAV
VVADETGKYFISVLSGHFGGANEICQLLAQKLGGEAVITTATDVQGKVGLDVLARKYVLRYADREVFKRVNAALARGEEV
KFFARSLPSDFPYPYLAEIEEEFSGIKVLISPYLIALKPNEYQLYPPAVWVGIGCRRGVEFTLLEKAVLEALQEGGVSLK
GVAGIASIDLKKDETALLELAAKYGLKTKFFTREELLEVINKKNLQQSSKVLTKVGVGNVCEAAAIKAAGMGNLILPKKI
FPKVSVALAEALRWWE

Sequences:

>Translated_336_residues
MIKNLIIFYFTAAGETLARRFLTLKLGGNVTLFSGKSAEIKNCLKKNWNNDTAFLFIGALGIAVRLIAPFIKDKFSDPAV
VVADETGKYFISVLSGHFGGANEICQLLAQKLGGEAVITTATDVQGKVGLDVLARKYVLRYADREVFKRVNAALARGEEV
KFFARSLPSDFPYPYLAEIEEEFSGIKVLISPYLIALKPNEYQLYPPAVWVGIGCRRGVEFTLLEKAVLEALQEGGVSLK
GVAGIASIDLKKDETALLELAAKYGLKTKFFTREELLEVINKKNLQQSSKVLTKVGVGNVCEAAAIKAAGMGNLILPKKI
FPKVSVALAEALRWWE
>Mature_336_residues
MIKNLIIFYFTAAGETLARRFLTLKLGGNVTLFSGKSAEIKNCLKKNWNNDTAFLFIGALGIAVRLIAPFIKDKFSDPAV
VVADETGKYFISVLSGHFGGANEICQLLAQKLGGEAVITTATDVQGKVGLDVLARKYVLRYADREVFKRVNAALARGEEV
KFFARSLPSDFPYPYLAEIEEEFSGIKVLISPYLIALKPNEYQLYPPAVWVGIGCRRGVEFTLLEKAVLEALQEGGVSLK
GVAGIASIDLKKDETALLELAAKYGLKTKFFTREELLEVINKKNLQQSSKVLTKVGVGNVCEAAAIKAAGMGNLILPKKI
FPKVSVALAEALRWWE

Specific function: Unknown

COG id: COG2073

COG function: function code H; Cobalamin biosynthesis protein CbiG

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR021745
- InterPro:   IPR021744
- InterPro:   IPR002750 [H]

Pfam domain/function: PF01890 CbiG; PF11761 CbiG_mid; PF11760 CbiG_N [H]

EC number: 2.1.1.133

Molecular weight: Translated: 36786; Mature: 36786

Theoretical pI: Translated: 9.61; Mature: 9.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKNLIIFYFTAAGETLARRFLTLKLGGNVTLFSGKSAEIKNCLKKNWNNDTAFLFIGAL
CCCCEEEEEEECCCHHHHHHEEEEEECCCEEEECCCCHHHHHHHHHCCCCCEEEEHHHHH
GIAVRLIAPFIKDKFSDPAVVVADETGKYFISVLSGHFGGANEICQLLAQKLGGEAVITT
HHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHCCCCCHHHHHHHHHHHCCCCEEEEE
ATDVQGKVGLDVLARKYVLRYADREVFKRVNAALARGEEVKFFARSLPSDFPYPYLAEIE
ECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCHHHHHH
EEFSGIKVLISPYLIALKPNEYQLYPPAVWVGIGCRRGVEFTLLEKAVLEALQEGGVSLK
HHHCCCEEEECCEEEEECCCCEEEECCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCEEE
GVAGIASIDLKKDETALLELAAKYGLKTKFFTREELLEVINKKNLQQSSKVLTKVGVGNV
ECCCEEEEECCCCHHHHHHHHHHHCCCCEEECHHHHHHHHHHHCHHHHHHHHHHCCCCCH
CEAAAIKAAGMGNLILPKKIFPKVSVALAEALRWWE
HHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIKNLIIFYFTAAGETLARRFLTLKLGGNVTLFSGKSAEIKNCLKKNWNNDTAFLFIGAL
CCCCEEEEEEECCCHHHHHHEEEEEECCCEEEECCCCHHHHHHHHHCCCCCEEEEHHHHH
GIAVRLIAPFIKDKFSDPAVVVADETGKYFISVLSGHFGGANEICQLLAQKLGGEAVITT
HHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHCCCCCHHHHHHHHHHHCCCCEEEEE
ATDVQGKVGLDVLARKYVLRYADREVFKRVNAALARGEEVKFFARSLPSDFPYPYLAEIE
ECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCHHHHHH
EEFSGIKVLISPYLIALKPNEYQLYPPAVWVGIGCRRGVEFTLLEKAVLEALQEGGVSLK
HHHCCCEEEECCEEEEECCCCEEEECCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCEEE
GVAGIASIDLKKDETALLELAAKYGLKTKFFTREELLEVINKKNLQQSSKVLTKVGVGNV
ECCCEEEEECCCCHHHHHHHHHHHCCCCEEECHHHHHHHHHHHCHHHHHHHHHHCCCCCH
CEAAAIKAAGMGNLILPKKIFPKVSVALAEALRWWE
HHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: S-adenosyl-L-methionine; Precorrin 4

Specific reaction: S-adenosyl-L-methionine + precorrin-4 = S-adenosyl-L-homocysteine + precorrin-5

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8501034; 11677609 [H]