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The map label for this gene is yfnC [H]

Identifier: 78044177

GI number: 78044177

Start: 2164697

End: 2165869

Strand: Direct

Name: yfnC [H]

Synonym: CHY_2417

Alternate gene names: 78044177

Gene position: 2164697-2165869 (Clockwise)

Preceding gene: 78044356

Following gene: 78042789

Centisome position: 90.14

GC content: 45.01

Gene sequence:

>1173_bases
TTGAATTATAATTATAACAAAATTCGTTATGCGATTGCTTTTGGCCATTTCTGGATAGATTTTTACGCCAACGTCTTAGC
TTCTACCATGTACCTTTTAGCCCGGGACTTACACTTAAGCCTTACCCGCCAGGGAATTCTGGTAGCGGTTGTTTCGTTTG
CCGGTTCGGTCATGCAACCGTACCTGGGTTATCTGGTGGATAAAAAAGGAAAAAGCACCCATCTCTTATTCAGCCTTTTG
CTAATGGGATTACTTACTACCGCCACCGGACTGTTTCAAAATTTTTATCCCGTTTTAATCCTTTTTACCCTCGGCGCCTT
AGGCTCAGCCCTTTATCACCCCTTAGGGTCTGTGCTTACAACCAGCATCAGCGAAAAGAAAAACACCGCTGTTTCTTTTT
ACGTCACCTGGGGAAATATCGGCTACTCCATAGCCCCGGTAATTCTGGTGCCGGTGGTAGAAGCTTTGGGACGAAAAGGG
CTTTTACTTTTTTCTCTGCCTATGTTTTTAGCACTAATATTCCTCTATTTATCAAAAAGCCACCAGCTACCCCTTCCCCA
CGAAGAGCGTAAAGAAACTCTACCCTCCTTTCGGGCCACGATTAAAAGCGCCTTTACCGGCCTTCTGCTTTTAAACTTAA
TCGTTTGGGGCCGTGCCTGGATCCAGGTAGCCCTTGGCAACTATTCCATTCAGTATTTCCTGCATCAGGGGCTTTCGGCC
AACCAGAGCAGTATCCTTCTTTCGGCTTATCTTTTGGCCGGAACAGCAGGGGTGGTAGCGGGTGGTTTTGTAAGTGAAAA
GCACGGAGAAAGGTTTACCCTGCTTGCTACTTTCCTTTTGTCCGGAGCTACGTTAATAATGATGTTTTTCACTCCACCAC
CTTTTTCTTATCTTGGCATGCTTATAACCGGCTTTCTTTTAAACATGTCCTTCCCGGCCACCATCGTTATGGGGCAAAAC
TTAATCCCGGAAAACGCCGGAATGGTTTCCGGGATGATGATGGGGCTGGCTTTTGGTCTTGGCGGTATGGGTGCTATGCT
TACCGGTACGGTGGCTGATTATACCAGTCTTGCTTTTTCTTTAAAACTGTTGGTGGTGATTCCCTTTATTATCTCCGCTT
TAACGTTAGTTTATTTTCAAAAAATTTCCCTGCCTAAACCCAAAATAAAATAA

Upstream 100 bases:

>100_bases
CTAATCCCCCCTCCCTCCTTCCCCGAAGATTTACCGCTTCGGGGTTTTTTCTTTTTAAAAAATATGTTTTAATAGTAATG
TTGGACGGGAGGGAGAATAT

Downstream 100 bases:

>100_bases
TTTTTGACATATTTAGATTTTTCCTGTATATTTAAGTTAAATTTATTTTTTTGGAGGTTTTGCGATTTGCGCAAGTTTAA
GATTTTCACCGATAGTACCC

Product: putative fosmidomycin resistance protein

Products: fosmidomycin [Periplasm]; Proton [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 390; Mature: 390

Protein sequence:

>390_residues
MNYNYNKIRYAIAFGHFWIDFYANVLASTMYLLARDLHLSLTRQGILVAVVSFAGSVMQPYLGYLVDKKGKSTHLLFSLL
LMGLLTTATGLFQNFYPVLILFTLGALGSALYHPLGSVLTTSISEKKNTAVSFYVTWGNIGYSIAPVILVPVVEALGRKG
LLLFSLPMFLALIFLYLSKSHQLPLPHEERKETLPSFRATIKSAFTGLLLLNLIVWGRAWIQVALGNYSIQYFLHQGLSA
NQSSILLSAYLLAGTAGVVAGGFVSEKHGERFTLLATFLLSGATLIMMFFTPPPFSYLGMLITGFLLNMSFPATIVMGQN
LIPENAGMVSGMMMGLAFGLGGMGAMLTGTVADYTSLAFSLKLLVVIPFIISALTLVYFQKISLPKPKIK

Sequences:

>Translated_390_residues
MNYNYNKIRYAIAFGHFWIDFYANVLASTMYLLARDLHLSLTRQGILVAVVSFAGSVMQPYLGYLVDKKGKSTHLLFSLL
LMGLLTTATGLFQNFYPVLILFTLGALGSALYHPLGSVLTTSISEKKNTAVSFYVTWGNIGYSIAPVILVPVVEALGRKG
LLLFSLPMFLALIFLYLSKSHQLPLPHEERKETLPSFRATIKSAFTGLLLLNLIVWGRAWIQVALGNYSIQYFLHQGLSA
NQSSILLSAYLLAGTAGVVAGGFVSEKHGERFTLLATFLLSGATLIMMFFTPPPFSYLGMLITGFLLNMSFPATIVMGQN
LIPENAGMVSGMMMGLAFGLGGMGAMLTGTVADYTSLAFSLKLLVVIPFIISALTLVYFQKISLPKPKIK
>Mature_390_residues
MNYNYNKIRYAIAFGHFWIDFYANVLASTMYLLARDLHLSLTRQGILVAVVSFAGSVMQPYLGYLVDKKGKSTHLLFSLL
LMGLLTTATGLFQNFYPVLILFTLGALGSALYHPLGSVLTTSISEKKNTAVSFYVTWGNIGYSIAPVILVPVVEALGRKG
LLLFSLPMFLALIFLYLSKSHQLPLPHEERKETLPSFRATIKSAFTGLLLLNLIVWGRAWIQVALGNYSIQYFLHQGLSA
NQSSILLSAYLLAGTAGVVAGGFVSEKHGERFTLLATFLLSGATLIMMFFTPPPFSYLGMLITGFLLNMSFPATIVMGQN
LIPENAGMVSGMMMGLAFGLGGMGAMLTGTVADYTSLAFSLKLLVVIPFIISALTLVYFQKISLPKPKIK

Specific function: Confers The Resistance Against Fosmidomycin. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily [H]

Homologues:

Organism=Escherichia coli, GI1786686, Length=372, Percent_Identity=28.494623655914, Blast_Score=95, Evalue=8e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 42580; Mature: 42580

Theoretical pI: Translated: 10.06; Mature: 10.06

Prosite motif: PS50850 MFS ; PS00216 SUGAR_TRANSPORT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYNYNKIRYAIAFGHFWIDFYANVLASTMYLLARDLHLSLTRQGILVAVVSFAGSVMQP
CCCCHHHEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YLGYLVDKKGKSTHLLFSLLLMGLLTTATGLFQNFYPVLILFTLGALGSALYHPLGSVLT
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TSISEKKNTAVSFYVTWGNIGYSIAPVILVPVVEALGRKGLLLFSLPMFLALIFLYLSKS
HHHHHCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCC
HQLPLPHEERKETLPSFRATIKSAFTGLLLLNLIVWGRAWIQVALGNYSIQYFLHQGLSA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCC
NQSSILLSAYLLAGTAGVVAGGFVSEKHGERFTLLATFLLSGATLIMMFFTPPPFSYLGM
CCHHHHHHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHCCHHEEEEEECCCCHHHHHH
LITGFLLNMSFPATIVMGQNLIPENAGMVSGMMMGLAFGLGGMGAMLTGTVADYTSLAFS
HHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
LKLLVVIPFIISALTLVYFQKISLPKPKIK
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MNYNYNKIRYAIAFGHFWIDFYANVLASTMYLLARDLHLSLTRQGILVAVVSFAGSVMQP
CCCCHHHEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YLGYLVDKKGKSTHLLFSLLLMGLLTTATGLFQNFYPVLILFTLGALGSALYHPLGSVLT
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TSISEKKNTAVSFYVTWGNIGYSIAPVILVPVVEALGRKGLLLFSLPMFLALIFLYLSKS
HHHHHCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCC
HQLPLPHEERKETLPSFRATIKSAFTGLLLLNLIVWGRAWIQVALGNYSIQYFLHQGLSA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCC
NQSSILLSAYLLAGTAGVVAGGFVSEKHGERFTLLATFLLSGATLIMMFFTPPPFSYLGM
CCHHHHHHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHCCHHEEEEEECCCCHHHHHH
LITGFLLNMSFPATIVMGQNLIPENAGMVSGMMMGLAFGLGGMGAMLTGTVADYTSLAFS
HHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
LKLLVVIPFIISALTLVYFQKISLPKPKIK
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: fosmidomycin [Cytoplasm]; Proton [Periplasm] [C]

Specific reaction: fosmidomycin [Cytoplasm] + Proton [Periplasm] = fosmidomycin [Periplasm] + Proton [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9141694; 9384377 [H]