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The map label for this gene is pilC [H]

Identifier: 78043922

GI number: 78043922

Start: 547285

End: 548493

Strand: Direct

Name: pilC [H]

Synonym: CHY_0632

Alternate gene names: 78043922

Gene position: 547285-548493 (Clockwise)

Preceding gene: 78044094

Following gene: 78043168

Centisome position: 22.79

GC content: 45.24

Gene sequence:

>1209_bases
ATGCCCCAGTACCGGTATAAAGCTAAAGACCTTTCGGGACGAGTGGTTAGTGGTTTGGTAGAAGCGGAATCGGAAGTAGG
GGCGAGAAATCTCCTCCGGGAAAAACGCTTTTTTGTTCTGGAATTGAAAAAAAGTGATGGAGCGGTAAATTCAGGATTTT
CCTTTAGTTTTCAACGAAAGTTAAAAGCCAAGGATTTAGCCTTAATGGCCAAACAGTTAGGGACAATGATAGCGGCCGGG
GTACCCCTTCTGACGGCGGTCAATGTCCTGTCCCGCCAGGTGGAAAATAAAACTTTGAAAAAAAGCCTCATTAGAATTGA
AGAAAAACTTCGTAACGGTAATACCCTTTCCGAAAGCTTGCGGGAGGAGAAAATTTTTCCCGAACTTATGTGCAGTATGG
TGGAAGTGGGCGAAGTTGGCGGTGTTTTAGACAACGTCCTTGATCGGCTTTCCCTTCACTACGAAAAGGAAGCCCAGTTA
AGCGAAAAAATCCGCTCGGCGATGACTTACCCGATGGTGGTTTTATTTGCTGCCATTGCCGCTGTCTTGGTACTGGTTAC
ATACGTACTTCCGCAGTTTACAGGTATCTTGTTGCAGGCAAATATCGAACTTCCTCTGATTACTCAGGTAGTCATAAAAA
TAACCAATTTTTTCTCCCAGCATGCGGCAACTATTTTTCTCACTTTAGGTGCAATTATTGGAGGACTTCTTTACTGGTTT
TCAACCCCTCCAGGGCGAAAAATCCGGGATCAGTTATCCCTTAATATGCCCCTTATTGGTACTCTGGTTTTAAAAGGGAT
TATTGCCCGCTTTTCCCGAACCATGGCAACTTTAGTCCAGGGCGGGGTTCCGATGCTTCAGTCTTTAAGGGTGGTGCAAA
AAACCCTTGGTAATGGGGAAATGCAAAAAGTACTGGAGTTAGCCGAAGATAAGGTTAGAGAAGGAGAAAGCCTGGCCACT
TTTTTAGCCCAGAGCCGTTGGTTTCCGCCGCTTCTAACCCAGATGATGTTAGTGGGGGAAGAAACCGGTCAGCTGGATGC
AATGCTTACCAAAGCTGCTGATTTCTATGAAGCGGAAGTAGATGCGGCGGTGGGAAGGCTTTCGTCAATAATTGAGCCGG
TCTTGATTTTATTTATGGGTGGCATTGTAGGCTTAATCATTGTGTCCATCATGCTGCCGATGTTTAACATGGTAAATGCG
GTTAAATAG

Upstream 100 bases:

>100_bases
TAAATTTGGGAAAAATTTTTGTCGAAGAAAATTACAAAATATATTAAAATATTAAACAAAAGGAATAGTTTGTGAAGGTT
ATAAGGAAAGGAGGAGAGTT

Downstream 100 bases:

>100_bases
TTTTTACCCCCTTTTTTTCGGGGTAAAAATAATGGGTACTTAATGAAAAAGTTTCATAACTTTGCCGAGAGAGGAGGTGA
AAGGGATGAAAATAAGACAA

Product: type IV pilus assembly protein PilC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 402; Mature: 401

Protein sequence:

>402_residues
MPQYRYKAKDLSGRVVSGLVEAESEVGARNLLREKRFFVLELKKSDGAVNSGFSFSFQRKLKAKDLALMAKQLGTMIAAG
VPLLTAVNVLSRQVENKTLKKSLIRIEEKLRNGNTLSESLREEKIFPELMCSMVEVGEVGGVLDNVLDRLSLHYEKEAQL
SEKIRSAMTYPMVVLFAAIAAVLVLVTYVLPQFTGILLQANIELPLITQVVIKITNFFSQHAATIFLTLGAIIGGLLYWF
STPPGRKIRDQLSLNMPLIGTLVLKGIIARFSRTMATLVQGGVPMLQSLRVVQKTLGNGEMQKVLELAEDKVREGESLAT
FLAQSRWFPPLLTQMMLVGEETGQLDAMLTKAADFYEAEVDAAVGRLSSIIEPVLILFMGGIVGLIIVSIMLPMFNMVNA
VK

Sequences:

>Translated_402_residues
MPQYRYKAKDLSGRVVSGLVEAESEVGARNLLREKRFFVLELKKSDGAVNSGFSFSFQRKLKAKDLALMAKQLGTMIAAG
VPLLTAVNVLSRQVENKTLKKSLIRIEEKLRNGNTLSESLREEKIFPELMCSMVEVGEVGGVLDNVLDRLSLHYEKEAQL
SEKIRSAMTYPMVVLFAAIAAVLVLVTYVLPQFTGILLQANIELPLITQVVIKITNFFSQHAATIFLTLGAIIGGLLYWF
STPPGRKIRDQLSLNMPLIGTLVLKGIIARFSRTMATLVQGGVPMLQSLRVVQKTLGNGEMQKVLELAEDKVREGESLAT
FLAQSRWFPPLLTQMMLVGEETGQLDAMLTKAADFYEAEVDAAVGRLSSIIEPVLILFMGGIVGLIIVSIMLPMFNMVNA
VK
>Mature_401_residues
PQYRYKAKDLSGRVVSGLVEAESEVGARNLLREKRFFVLELKKSDGAVNSGFSFSFQRKLKAKDLALMAKQLGTMIAAGV
PLLTAVNVLSRQVENKTLKKSLIRIEEKLRNGNTLSESLREEKIFPELMCSMVEVGEVGGVLDNVLDRLSLHYEKEAQLS
EKIRSAMTYPMVVLFAAIAAVLVLVTYVLPQFTGILLQANIELPLITQVVIKITNFFSQHAATIFLTLGAIIGGLLYWFS
TPPGRKIRDQLSLNMPLIGTLVLKGIIARFSRTMATLVQGGVPMLQSLRVVQKTLGNGEMQKVLELAEDKVREGESLATF
LAQSRWFPPLLTQMMLVGEETGQLDAMLTKAADFYEAEVDAAVGRLSSIIEPVLILFMGGIVGLIIVSIMLPMFNMVNAV
K

Specific function: Involved in the translocation of the type IV pilin (pilA) [H]

COG id: COG1459

COG function: function code NU; Type II secretory pathway, component PulF

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP F family [H]

Homologues:

Organism=Escherichia coli, GI1789724, Length=397, Percent_Identity=29.9748110831234, Blast_Score=190, Evalue=1e-49,
Organism=Escherichia coli, GI1786295, Length=402, Percent_Identity=26.865671641791, Blast_Score=137, Evalue=1e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003004
- InterPro:   IPR018076
- InterPro:   IPR001992 [H]

Pfam domain/function: PF00482 GSPII_F [H]

EC number: NA

Molecular weight: Translated: 44309; Mature: 44178

Theoretical pI: Translated: 9.75; Mature: 9.75

Prosite motif: PS00874 T2SP_F

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPQYRYKAKDLSGRVVSGLVEAESEVGARNLLREKRFFVLELKKSDGAVNSGFSFSFQRK
CCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHH
LKAKDLALMAKQLGTMIAAGVPLLTAVNVLSRQVENKTLKKSLIRIEEKLRNGNTLSESL
HHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
REEKIFPELMCSMVEVGEVGGVLDNVLDRLSLHYEKEAQLSEKIRSAMTYPMVVLFAAIA
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVLVLVTYVLPQFTGILLQANIELPLITQVVIKITNFFSQHAATIFLTLGAIIGGLLYWF
HHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
STPPGRKIRDQLSLNMPLIGTLVLKGIIARFSRTMATLVQGGVPMLQSLRVVQKTLGNGE
CCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCHH
MQKVLELAEDKVREGESLATFLAQSRWFPPLLTQMMLVGEETGQLDAMLTKAADFYEAEV
HHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
DAAVGRLSSIIEPVLILFMGGIVGLIIVSIMLPMFNMVNAVK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PQYRYKAKDLSGRVVSGLVEAESEVGARNLLREKRFFVLELKKSDGAVNSGFSFSFQRK
CCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHH
LKAKDLALMAKQLGTMIAAGVPLLTAVNVLSRQVENKTLKKSLIRIEEKLRNGNTLSESL
HHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
REEKIFPELMCSMVEVGEVGGVLDNVLDRLSLHYEKEAQLSEKIRSAMTYPMVVLFAAIA
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVLVLVTYVLPQFTGILLQANIELPLITQVVIKITNFFSQHAATIFLTLGAIIGGLLYWF
HHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
STPPGRKIRDQLSLNMPLIGTLVLKGIIARFSRTMATLVQGGVPMLQSLRVVQKTLGNGE
CCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCHH
MQKVLELAEDKVREGESLATFLAQSRWFPPLLTQMMLVGEETGQLDAMLTKAADFYEAEV
HHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
DAAVGRLSSIIEPVLILFMGGIVGLIIVSIMLPMFNMVNAVK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1971619; 10984043 [H]