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The map label for this gene is xapA [C]

Identifier: 78043801

GI number: 78043801

Start: 1200868

End: 1201674

Strand: Direct

Name: xapA [C]

Synonym: CHY_1342

Alternate gene names: 78043801

Gene position: 1200868-1201674 (Clockwise)

Preceding gene: 78043498

Following gene: 78044373

Centisome position: 50.0

GC content: 38.79

Gene sequence:

>807_bases
GTGAATGTTGATATAGCTTATATAGGTGGATCAAGTACCTTGGGAATAGGATTTCCGGAAAAGTTTCTACCCCCTGATGT
TAAATTTATAAAAGAAGAAACTTTTACAACACCTTATGGTCCATCTCCCAAAATATATTTCTTAGAAATCGGTACAAAGA
AAGTAGTTCATGTAAAAATGCACGGCTGGCGTCCCGGGGTTTCTCGAAGAGATGCCTCTCTCCAGGTATTCTGGGTTTTT
CAACAGTTGGGAGTAAACAAAATATTTTCTGAAGGCGGGGTAGGGGCTGTAAATCATTTGTTAGAATTAAGGGATTACGT
TATTCCTACCGATTACCTTGATTTTACCATGCGTAAAGATGTCCATCTAACTTCTAATTACCTTTTAATTATGAGAAAAC
CTACCTGCCCGGAAATAAATCGCGCATTATTTGAAAGTGCTAAAACTCATGCCAAAGGCAGAGTTTTTCAGCGCGGAATT
TATGCTTGTACCGATGGTCGCCACTTTGAAAGCGTTGCGGAAGTTGCCTTTTTGAAAAATGCCGGAGCAGATGTAATAGG
TCAGAGTATGGTCCCGGAAGTTTATCTTGCCCGGGAAATTGGTGCCTGCTACGGCCGAATCGATTTGGTAGTTAATTATG
CCGAAGGAATTATTAAAGAGTGGGAACACGAGGAATTAAAAGATATTTATTATAATGATGCTCTTACAAATTTGCAAATA
GTTACCGAGGCAATTTTAAATTTTAACCCGCAAAATACCTGCGAATGCCAGGATTTTCGCAAGGAAACATTATTAAAACT
TGAATGA

Upstream 100 bases:

>100_bases
GAAGTTTTAAAAATGCTTGCGGACTTAAATTTTTCGGTTTTATCGGTAAACCATACACCTACCAGGAGTTTTTATTTAGC
TGTAAAAGGAGGAAGTAGTA

Downstream 100 bases:

>100_bases
AATTTCCATTTCCTTGCAGGCAGGTAATTTTTTATCGTCGTCGAATTTTATAAACAAGCTTCGAAAGCTTGTTATTTTTT
TAAGGAGAGGTTTACGATGG

Product: phosphorylase family 2 protein

Products: ribose-1-phosphate; xanthine [C]

Alternate protein names: NA

Number of amino acids: Translated: 268; Mature: 268

Protein sequence:

>268_residues
MNVDIAYIGGSSTLGIGFPEKFLPPDVKFIKEETFTTPYGPSPKIYFLEIGTKKVVHVKMHGWRPGVSRRDASLQVFWVF
QQLGVNKIFSEGGVGAVNHLLELRDYVIPTDYLDFTMRKDVHLTSNYLLIMRKPTCPEINRALFESAKTHAKGRVFQRGI
YACTDGRHFESVAEVAFLKNAGADVIGQSMVPEVYLAREIGACYGRIDLVVNYAEGIIKEWEHEELKDIYYNDALTNLQI
VTEAILNFNPQNTCECQDFRKETLLKLE

Sequences:

>Translated_268_residues
MNVDIAYIGGSSTLGIGFPEKFLPPDVKFIKEETFTTPYGPSPKIYFLEIGTKKVVHVKMHGWRPGVSRRDASLQVFWVF
QQLGVNKIFSEGGVGAVNHLLELRDYVIPTDYLDFTMRKDVHLTSNYLLIMRKPTCPEINRALFESAKTHAKGRVFQRGI
YACTDGRHFESVAEVAFLKNAGADVIGQSMVPEVYLAREIGACYGRIDLVVNYAEGIIKEWEHEELKDIYYNDALTNLQI
VTEAILNFNPQNTCECQDFRKETLLKLE
>Mature_268_residues
MNVDIAYIGGSSTLGIGFPEKFLPPDVKFIKEETFTTPYGPSPKIYFLEIGTKKVVHVKMHGWRPGVSRRDASLQVFWVF
QQLGVNKIFSEGGVGAVNHLLELRDYVIPTDYLDFTMRKDVHLTSNYLLIMRKPTCPEINRALFESAKTHAKGRVFQRGI
YACTDGRHFESVAEVAFLKNAGADVIGQSMVPEVYLAREIGACYGRIDLVVNYAEGIIKEWEHEELKDIYYNDALTNLQI
VTEAILNFNPQNTCECQDFRKETLLKLE

Specific function: The Nucleoside Phosphorylases Catalyze The Phosphorolytic Breakdown Of The N-Glycosidic Bond In The Nucleoside Molecule, With The Formation Of The Corresponding Free Bases And Pentose-1-Phosphate. This Protein Can Degrade All Purine Nucleosides Except Ade

COG id: COG0005

COG function: function code F; Purine nucleoside phosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/MTAP phosphorylase family [H]

Homologues:

Organism=Homo sapiens, GI47132622, Length=234, Percent_Identity=28.2051282051282, Blast_Score=77, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010044
- InterPro:   IPR000845
- InterPro:   IPR001369
- InterPro:   IPR018099 [H]

Pfam domain/function: PF01048 PNP_UDP_1 [H]

EC number: 2.4.2.- [C]

Molecular weight: Translated: 30450; Mature: 30450

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVDIAYIGGSSTLGIGFPEKFLPPDVKFIKEETFTTPYGPSPKIYFLEIGTKKVVHVKM
CCEEEEEECCCCEECCCCCHHHCCCCHHHHHHHCCCCCCCCCCEEEEEEECCCEEEEEEE
HGWRPGVSRRDASLQVFWVFQQLGVNKIFSEGGVGAVNHLLELRDYVIPTDYLDFTMRKD
ECCCCCCCCCCCCEEEEEEHHHHCHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHCCCC
VHLTSNYLLIMRKPTCPEINRALFESAKTHAKGRVFQRGIYACTDGRHFESVAEVAFLKN
EEEECCEEEEEECCCCCHHHHHHHHHHHHHHCCHHHHCCEEEECCCCHHHHHHHHHHHHC
AGADVIGQSMVPEVYLAREIGACYGRIDLVVNYAEGIIKEWEHEELKDIYYNDALTNLQI
CCHHHHHHHHCCHHHHHHHHHHHHHHHHHEEEHHHHHHHHCCHHHHHHHHHHHHHHHHHH
VTEAILNFNPQNTCECQDFRKETLLKLE
HHHHHHCCCCCCCCCHHHHHHHHHEECC
>Mature Secondary Structure
MNVDIAYIGGSSTLGIGFPEKFLPPDVKFIKEETFTTPYGPSPKIYFLEIGTKKVVHVKM
CCEEEEEECCCCEECCCCCHHHCCCCHHHHHHHCCCCCCCCCCEEEEEEECCCEEEEEEE
HGWRPGVSRRDASLQVFWVFQQLGVNKIFSEGGVGAVNHLLELRDYVIPTDYLDFTMRKD
ECCCCCCCCCCCCEEEEEEHHHHCHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHCCCC
VHLTSNYLLIMRKPTCPEINRALFESAKTHAKGRVFQRGIYACTDGRHFESVAEVAFLKN
EEEECCEEEEEECCCCCHHHHHHHHHHHHHHCCHHHHCCEEEECCCCHHHHHHHHHHHHC
AGADVIGQSMVPEVYLAREIGACYGRIDLVVNYAEGIIKEWEHEELKDIYYNDALTNLQI
CCHHHHHHHHCCHHHHHHHHHHHHHHHHHEEEHHHHHHHHCCHHHHHHHHHHHHHHHHHH
VTEAILNFNPQNTCECQDFRKETLLKLE
HHHHHHCCCCCCCCCHHHHHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: xanthosine; phosphate [C]

Specific reaction: xanthosine + phosphate = ribose-1-phosphate + xanthine [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12622808 [H]