Click here to switch to the map view.

The map label for this gene is hrcA

Identifier: 78043787

GI number: 78043787

Start: 354698

End: 355723

Strand: Direct

Name: hrcA

Synonym: CHY_0412

Alternate gene names: 78043787

Gene position: 354698-355723 (Clockwise)

Preceding gene: 78044379

Following gene: 78043200

Centisome position: 14.77

GC content: 39.28

Gene sequence:

>1026_bases
ATGATTGATGAGCGGAAAAGAAAAATTTTAATGGCAATAGTTCAGGACTACATCTCTACCGCTGAACCGGTAGGCTCAAG
AACTATTGCCAAAAAATACGACCTGGGTATTAGCCCGGCAACCATCAGGAATGAAATGGCAGATTTAGAAGAAATGGGCT
ATTTAGAGCAGCCCCATACCAGTGCCGGGAGAATTCCTTCGGTTTTGGGCTACCGCTATTACGTCGACTACCTTATGGAA
AAACCCTCTTTGAGCCGTGAAGAAGAAGAATTTATCCGGAAAGTTTATGAAGATAAAATCAACAGTATTGGCGATTTGCT
GGAAAAAACGGGCAAAGTTTTGTCCAGTCTTACCCGTTATACCGCCGTTGTGCTTTCTCCGGAGGCAGGAAAAGTACCGT
TAAAACACCTGCAGTTAGTGCTTTTACAGCCGGGGAAGGTATTGTTAATTATAGTATTAGAAGATGGGACCTTACACCAT
CGGGCTTTTGAAGTGCCCGGGGATATTACTGCTCAGGATTTAGAAAAAGTTTCAGCAATTTTAAATGCTAAACTTTACGG
AGTAAATCCCGAAAAGATTCGTTATTCGCTTATTAAAGAAATATACTACGAATTAGCCCAGCACCAGAATTTAATTAATA
TTACTTTAGAATTAATCAGTAATTTAAACCAAGATAATCAGGAGCATAAGATAATCTTGGGCGGACTAATTAACCTTTTT
AACCAGCCGGAGTTTAAAAATGTGGAAAAGGTAAAAACCTTATTAAGCATATTGGAACAGGAAGAGAAAATAAGGGAAAT
CTTTTCCCAGTTAAATGTTGGGGTTAACGTGAAAATCGGGAGCGAGTTAAATTTAAAAGAAATTGAAGACTGCAGCATGA
TTGCTGCCGGCTACTTTTCCTACGGAAATAGCGTGGGCTTTATAGGAGTTTTAGGACCTACGCGTATGGAATACGCTAAA
ACCGTGGCGACGGTGGAGTTTTTAAGTAAGTACTTGTCGGAAATTATTGGTAATAAAAACTTTTAA

Upstream 100 bases:

>100_bases
GAGTTTATCTAAACTTGACAAAAAATGCTTGACAGTGCTATTTTTAATTTGAAGTTAGCACTCAACAAAAGAGAGTGCTA
ACAAAAAGGGGTGAAGCGGT

Downstream 100 bases:

>100_bases
CAGGAGGATTTAAGGTTGAAAAAAGAAAACCAAACCCAGGAAATTGAAGAACGCTATCAGGCCCTTTTTTCCAATGCAGC
AGCGGTAAAAGCCTTAACCC

Product: heat-inducible transcription repressor HrcA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 341; Mature: 341

Protein sequence:

>341_residues
MIDERKRKILMAIVQDYISTAEPVGSRTIAKKYDLGISPATIRNEMADLEEMGYLEQPHTSAGRIPSVLGYRYYVDYLME
KPSLSREEEEFIRKVYEDKINSIGDLLEKTGKVLSSLTRYTAVVLSPEAGKVPLKHLQLVLLQPGKVLLIIVLEDGTLHH
RAFEVPGDITAQDLEKVSAILNAKLYGVNPEKIRYSLIKEIYYELAQHQNLINITLELISNLNQDNQEHKIILGGLINLF
NQPEFKNVEKVKTLLSILEQEEKIREIFSQLNVGVNVKIGSELNLKEIEDCSMIAAGYFSYGNSVGFIGVLGPTRMEYAK
TVATVEFLSKYLSEIIGNKNF

Sequences:

>Translated_341_residues
MIDERKRKILMAIVQDYISTAEPVGSRTIAKKYDLGISPATIRNEMADLEEMGYLEQPHTSAGRIPSVLGYRYYVDYLME
KPSLSREEEEFIRKVYEDKINSIGDLLEKTGKVLSSLTRYTAVVLSPEAGKVPLKHLQLVLLQPGKVLLIIVLEDGTLHH
RAFEVPGDITAQDLEKVSAILNAKLYGVNPEKIRYSLIKEIYYELAQHQNLINITLELISNLNQDNQEHKIILGGLINLF
NQPEFKNVEKVKTLLSILEQEEKIREIFSQLNVGVNVKIGSELNLKEIEDCSMIAAGYFSYGNSVGFIGVLGPTRMEYAK
TVATVEFLSKYLSEIIGNKNF
>Mature_341_residues
MIDERKRKILMAIVQDYISTAEPVGSRTIAKKYDLGISPATIRNEMADLEEMGYLEQPHTSAGRIPSVLGYRYYVDYLME
KPSLSREEEEFIRKVYEDKINSIGDLLEKTGKVLSSLTRYTAVVLSPEAGKVPLKHLQLVLLQPGKVLLIIVLEDGTLHH
RAFEVPGDITAQDLEKVSAILNAKLYGVNPEKIRYSLIKEIYYELAQHQNLINITLELISNLNQDNQEHKIILGGLINLF
NQPEFKNVEKVKTLLSILEQEEKIREIFSQLNVGVNVKIGSELNLKEIEDCSMIAAGYFSYGNSVGFIGVLGPTRMEYAK
TVATVEFLSKYLSEIIGNKNF

Specific function: Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons

COG id: COG1420

COG function: function code K; Transcriptional regulator of heat shock gene

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hrcA family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HRCA_CARHZ (Q3AF11)

Other databases:

- EMBL:   CP000141
- RefSeq:   YP_359273.1
- ProteinModelPortal:   Q3AF11
- SMR:   Q3AF11
- STRING:   Q3AF11
- GeneID:   3726644
- GenomeReviews:   CP000141_GR
- KEGG:   chy:CHY_0412
- NMPDR:   fig|246194.3.peg.686
- TIGR:   CHY_0412
- eggNOG:   COG1420
- HOGENOM:   HBG729878
- OMA:   LEQPHTS
- BioCyc:   CHYD246194:CHY_0412-MONOMER
- GO:   GO:0006350
- HAMAP:   MF_00081
- InterPro:   IPR002571
- InterPro:   IPR021153
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- PIRSF:   PIRSF005485
- TIGRFAMs:   TIGR00331

Pfam domain/function: PF01628 HrcA

EC number: NA

Molecular weight: Translated: 38513; Mature: 38513

Theoretical pI: Translated: 5.51; Mature: 5.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDERKRKILMAIVQDYISTAEPVGSRTIAKKYDLGISPATIRNEMADLEEMGYLEQPHT
CCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCC
SAGRIPSVLGYRYYVDYLMEKPSLSREEEEFIRKVYEDKINSIGDLLEKTGKVLSSLTRY
CCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TAVVLSPEAGKVPLKHLQLVLLQPGKVLLIIVLEDGTLHHRAFEVPGDITAQDLEKVSAI
HEEEECCCCCCCCHHHHHHHEECCCCEEEEEEECCCCCCCEEECCCCCCCHHHHHHHHHH
LNAKLYGVNPEKIRYSLIKEIYYELAQHQNLINITLELISNLNQDNQEHKIILGGLINLF
HHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCEEHHHHHHHHH
NQPEFKNVEKVKTLLSILEQEEKIREIFSQLNVGVNVKIGSELNLKEIEDCSMIAAGYFS
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHH
YGNSVGFIGVLGPTRMEYAKTVATVEFLSKYLSEIIGNKNF
CCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MIDERKRKILMAIVQDYISTAEPVGSRTIAKKYDLGISPATIRNEMADLEEMGYLEQPHT
CCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCC
SAGRIPSVLGYRYYVDYLMEKPSLSREEEEFIRKVYEDKINSIGDLLEKTGKVLSSLTRY
CCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TAVVLSPEAGKVPLKHLQLVLLQPGKVLLIIVLEDGTLHHRAFEVPGDITAQDLEKVSAI
HEEEECCCCCCCCHHHHHHHEECCCCEEEEEEECCCCCCCEEECCCCCCCHHHHHHHHHH
LNAKLYGVNPEKIRYSLIKEIYYELAQHQNLINITLELISNLNQDNQEHKIILGGLINLF
HHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCEEHHHHHHHHH
NQPEFKNVEKVKTLLSILEQEEKIREIFSQLNVGVNVKIGSELNLKEIEDCSMIAAGYFS
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHH
YGNSVGFIGVLGPTRMEYAKTVATVEFLSKYLSEIIGNKNF
CCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA