Click here to switch to the map view.

The map label for this gene is yflS [H]

Identifier: 78043316

GI number: 78043316

Start: 49465

End: 50865

Strand: Direct

Name: yflS [H]

Synonym: CHY_0060

Alternate gene names: 78043316

Gene position: 49465-50865 (Clockwise)

Preceding gene: 78045158

Following gene: 78044230

Centisome position: 2.06

GC content: 40.54

Gene sequence:

>1401_bases
ATGAATAAAAAAATTCGCGCATTGCTAACCTGTGCTGTAGGTTTAGCAATTTGGTTTTCCCCAATACCGACAGGCTTAGA
TCCCAAAGCTTGGCACTTGTTAGCGATTTTTGTGGCGACAATTATAGGTTTTATCTTGCAGCCTCTACCAATTGGCGCAA
TAGCTTTTATTAGTGTCACATTATCAGCTCTTACTGGGATTTTAGATGCCAAAGCTGCATTGGCGGGGTTTGCAAATTCC
ACAATTTGGCTGATTGTTTCTGCTTTTATATTTGCTATAGGTTTTGTTAAAACCGGTTTGGGATTACGAATAGCCTATTA
TTTAATCCGCTTATTAGGCGATAGTACTTTAAAGTTGGGGTACACATTGGTATTAAGCGATTTAATTATAAGTCCTGCCA
CACCTTCTAATACGGCCCGGGCGGGGGGAGTATTATTCCCGATTGTACGGAGTCTTGCCGAGGCTTTTGGCTCTAAACCT
GGGGAGTCCCCTCGCAAAGTGGGTGCATACCTTATGCAAACAGCATATCAAGGTAATGCTATTACTTCAGCCATGTTTTT
AACTTCGATGGCTGGTAACCCGCTTATTGCACTTCTTGCTTTGAAAACTCTCAAGATAGACATTACTTGGAATCTGTGGG
CTAAAGCAGCAATTGTACCTGGAATAATTTCAATCTTAGTAATTCCTTACTTGCTTTATAAAATTTACCCACCAGAAATC
AAGAAAACACCTGAAGCTAAAGAAATTGCGGCTAAGGAACTGGTTAAAATGGGACCTATGAAATTTGAAGAAAAAGTATT
AGCTATTGTATTTATTGGGGCTCTAATCTTATGGGCTACCTCCCAATATACCAAAATTGATGCTACTATTGTAGCAATGT
TAGGCGTTTCTGCCATGCTAGTAGCAAAAGTTATTGATTGGAAAGATGTTCTGGCTGAAAAAGGAGCATGGGATACCTTA
GTGTGGATGGGTGTGTTAGTAGCACTAGCTGGTAATCTTTCTGAGCTAGGTTTTATTCCCTGGTTTGCGAAAAACGTAGG
GAATATGATTTCTGGAATTTCATGGTTCTGGGCGTTCGTTATTCTTCTGGTAGTTTACCTTTATGCTCATTATGGATTTG
CTAGCTTAACTGCTCATATTACTGCAATGTATGCTGCTTTTGCTTCTGTTGCAGTGGCAGCCGGTGCACCACCTTATCTT
GTAGCACTATCTTTAGCCTTTATGTCTAATTTGTGTATGTCTTTGACCCATTATGCTGCAGGTCCATCCCCGATTTATTT
TGGTGCAGGCTATGTTGATCAGGGAACATGGTGGAAACTTGGTTTTATTGTTTCTATAGTAAACCTGTTTATCTGGGTTG
GTATCGGAGCAGTATGGTGGAAAGCCCTTGGACTCTGGTAA

Upstream 100 bases:

>100_bases
AAAGGATAAAATATATAGTGAAATGTGAATCATTTCACACACCCGTTGGGCCCAATGGGAATGGAAAATTAAAAATTTTT
AAAAGGAGAGAGTGAATTGT

Downstream 100 bases:

>100_bases
AGTTGCTTATATTACACCACTGGATCAGTTAGTTCACTGGTCCGGTGGTGTAAAAATTCTCATAAATGTGTTTTTTACTT
CTAAATTTGGAAAAAGGAAA

Product: anion transporter family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 466; Mature: 466

Protein sequence:

>466_residues
MNKKIRALLTCAVGLAIWFSPIPTGLDPKAWHLLAIFVATIIGFILQPLPIGAIAFISVTLSALTGILDAKAALAGFANS
TIWLIVSAFIFAIGFVKTGLGLRIAYYLIRLLGDSTLKLGYTLVLSDLIISPATPSNTARAGGVLFPIVRSLAEAFGSKP
GESPRKVGAYLMQTAYQGNAITSAMFLTSMAGNPLIALLALKTLKIDITWNLWAKAAIVPGIISILVIPYLLYKIYPPEI
KKTPEAKEIAAKELVKMGPMKFEEKVLAIVFIGALILWATSQYTKIDATIVAMLGVSAMLVAKVIDWKDVLAEKGAWDTL
VWMGVLVALAGNLSELGFIPWFAKNVGNMISGISWFWAFVILLVVYLYAHYGFASLTAHITAMYAAFASVAVAAGAPPYL
VALSLAFMSNLCMSLTHYAAGPSPIYFGAGYVDQGTWWKLGFIVSIVNLFIWVGIGAVWWKALGLW

Sequences:

>Translated_466_residues
MNKKIRALLTCAVGLAIWFSPIPTGLDPKAWHLLAIFVATIIGFILQPLPIGAIAFISVTLSALTGILDAKAALAGFANS
TIWLIVSAFIFAIGFVKTGLGLRIAYYLIRLLGDSTLKLGYTLVLSDLIISPATPSNTARAGGVLFPIVRSLAEAFGSKP
GESPRKVGAYLMQTAYQGNAITSAMFLTSMAGNPLIALLALKTLKIDITWNLWAKAAIVPGIISILVIPYLLYKIYPPEI
KKTPEAKEIAAKELVKMGPMKFEEKVLAIVFIGALILWATSQYTKIDATIVAMLGVSAMLVAKVIDWKDVLAEKGAWDTL
VWMGVLVALAGNLSELGFIPWFAKNVGNMISGISWFWAFVILLVVYLYAHYGFASLTAHITAMYAAFASVAVAAGAPPYL
VALSLAFMSNLCMSLTHYAAGPSPIYFGAGYVDQGTWWKLGFIVSIVNLFIWVGIGAVWWKALGLW
>Mature_466_residues
MNKKIRALLTCAVGLAIWFSPIPTGLDPKAWHLLAIFVATIIGFILQPLPIGAIAFISVTLSALTGILDAKAALAGFANS
TIWLIVSAFIFAIGFVKTGLGLRIAYYLIRLLGDSTLKLGYTLVLSDLIISPATPSNTARAGGVLFPIVRSLAEAFGSKP
GESPRKVGAYLMQTAYQGNAITSAMFLTSMAGNPLIALLALKTLKIDITWNLWAKAAIVPGIISILVIPYLLYKIYPPEI
KKTPEAKEIAAKELVKMGPMKFEEKVLAIVFIGALILWATSQYTKIDATIVAMLGVSAMLVAKVIDWKDVLAEKGAWDTL
VWMGVLVALAGNLSELGFIPWFAKNVGNMISGISWFWAFVILLVVYLYAHYGFASLTAHITAMYAAFASVAVAAGAPPYL
VALSLAFMSNLCMSLTHYAAGPSPIYFGAGYVDQGTWWKLGFIVSIVNLFIWVGIGAVWWKALGLW

Specific function: Might be a malate transporter [H]

COG id: COG0471

COG function: function code P; Di- and tricarboxylate transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the SLC13A transporter (TC 2.A.47) family [H]

Homologues:

Organism=Escherichia coli, GI1786986, Length=475, Percent_Identity=40.8421052631579, Blast_Score=340, Evalue=1e-94,
Organism=Escherichia coli, GI1786829, Length=466, Percent_Identity=37.1244635193133, Blast_Score=291, Evalue=4e-80,
Organism=Escherichia coli, GI1789444, Length=474, Percent_Identity=36.2869198312236, Blast_Score=271, Evalue=9e-74,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001898 [H]

Pfam domain/function: PF00939 Na_sulph_symp [H]

EC number: NA

Molecular weight: Translated: 50177; Mature: 50177

Theoretical pI: Translated: 9.88; Mature: 9.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKKIRALLTCAVGLAIWFSPIPTGLDPKAWHLLAIFVATIIGFILQPLPIGAIAFISVT
CCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
LSALTGILDAKAALAGFANSTIWLIVSAFIFAIGFVKTGLGLRIAYYLIRLLGDSTLKLG
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCHHHHH
YTLVLSDLIISPATPSNTARAGGVLFPIVRSLAEAFGSKPGESPRKVGAYLMQTAYQGNA
HHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCH
ITSAMFLTSMAGNPLIALLALKTLKIDITWNLWAKAAIVPGIISILVIPYLLYKIYPPEI
HHHHHHHHHHCCCHHHHHHHHHHHEEEEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
KKTPEAKEIAAKELVKMGPMKFEEKVLAIVFIGALILWATSQYTKIDATIVAMLGVSAML
CCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
VAKVIDWKDVLAEKGAWDTLVWMGVLVALAGNLSELGFIPWFAKNVGNMISGISWFWAFV
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHHHHHHHHHH
ILLVVYLYAHYGFASLTAHITAMYAAFASVAVAAGAPPYLVALSLAFMSNLCMSLTHYAA
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCC
GPSPIYFGAGYVDQGTWWKLGFIVSIVNLFIWVGIGAVWWKALGLW
CCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNKKIRALLTCAVGLAIWFSPIPTGLDPKAWHLLAIFVATIIGFILQPLPIGAIAFISVT
CCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
LSALTGILDAKAALAGFANSTIWLIVSAFIFAIGFVKTGLGLRIAYYLIRLLGDSTLKLG
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCHHHHH
YTLVLSDLIISPATPSNTARAGGVLFPIVRSLAEAFGSKPGESPRKVGAYLMQTAYQGNA
HHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCH
ITSAMFLTSMAGNPLIALLALKTLKIDITWNLWAKAAIVPGIISILVIPYLLYKIYPPEI
HHHHHHHHHHCCCHHHHHHHHHHHEEEEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
KKTPEAKEIAAKELVKMGPMKFEEKVLAIVFIGALILWATSQYTKIDATIVAMLGVSAML
CCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
VAKVIDWKDVLAEKGAWDTLVWMGVLVALAGNLSELGFIPWFAKNVGNMISGISWFWAFV
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHHHHHHHHHH
ILLVVYLYAHYGFASLTAHITAMYAAFASVAVAAGAPPYLVALSLAFMSNLCMSLTHYAA
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCC
GPSPIYFGAGYVDQGTWWKLGFIVSIVNLFIWVGIGAVWWKALGLW
CCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9272861; 9384377; 12949159 [H]