Click here to switch to the map view.

The map label for this gene is yggV [C]

Identifier: 78043192

GI number: 78043192

Start: 277017

End: 277625

Strand: Direct

Name: yggV [C]

Synonym: CHY_0315

Alternate gene names: 78043192

Gene position: 277017-277625 (Clockwise)

Preceding gene: 78042648

Following gene: 78044258

Centisome position: 11.54

GC content: 46.96

Gene sequence:

>609_bases
ATGCAGCGGATAGTAATAGCCAGTAAAAATCAAGGAAAGATCAAAGAATTTTCAGCGCTTTTAAGTTCTCTGGGTTTTTC
CTTTGTTAGTCTTTTGGATTTTCCGGAAATCGGGGAAATACCCGAAAAGGGGACAACCTTCGAAGACAACGCCCGGCAAA
AAGCCGTTACGGTTTCCAATTTTACCGGTTTGCCGGCACTGGCGGATGATTCGGGATTAGTGGTGGATGCCCTGGGAGGA
AGACCTGGGGTATTTTCTGCTCGTTATGCCGGAGAGCCCAAAGATGATTTGAAAAATATCCAAAAACTTCTAAAAGAATT
AGAAGGTGTACCCTGGGAAAAGAGGACGGCCCGCTTTGTCGCGGTACTTTGCCTTTATTTCCCTGACGGCTCACTTGTTA
CGGCCCGGGGGGAATGTGAGGGCTATATTTTAGAGGAAATGCGGGGTAGCGGTGGTTTTGGCTATGACCCGGTCTTTTAT
CTTCCGGATTACGGTAAAACTATGGCGGAACTTCCGTTAGAGATAAAAAACAAAATAAGCCACCGGGCCCGGGCGTTAGA
GGAGCTTTTAAGGAAGCTAAAGGAGGAAAATAGGTGGAGTACCTGGTAG

Upstream 100 bases:

>100_bases
CTGCAAAGGCTTTTAACACTGGCCCAGAAGGGGATCAGAGAGTTAATTGAACTTCAAAAACAGGCCCTGGGAGATATTGC
CCGGAGGATAGGGATGGAAA

Downstream 100 bases:

>100_bases
TTAGCGATACTCACGGACGCATTGAAAAGGTGATAAAATATGCGCGGAGCAGGAATTTTGCCGGAATAATTCATGCCGGG
GATTACTACCGGGACGGTAT

Product: RdgB/HAM1 family non-canonical purine NTP pyrophosphatase

Products: NA

Alternate protein names: Nucleoside triphosphate phosphohydrolase; NTPase [H]

Number of amino acids: Translated: 202; Mature: 202

Protein sequence:

>202_residues
MQRIVIASKNQGKIKEFSALLSSLGFSFVSLLDFPEIGEIPEKGTTFEDNARQKAVTVSNFTGLPALADDSGLVVDALGG
RPGVFSARYAGEPKDDLKNIQKLLKELEGVPWEKRTARFVAVLCLYFPDGSLVTARGECEGYILEEMRGSGGFGYDPVFY
LPDYGKTMAELPLEIKNKISHRARALEELLRKLKEENRWSTW

Sequences:

>Translated_202_residues
MQRIVIASKNQGKIKEFSALLSSLGFSFVSLLDFPEIGEIPEKGTTFEDNARQKAVTVSNFTGLPALADDSGLVVDALGG
RPGVFSARYAGEPKDDLKNIQKLLKELEGVPWEKRTARFVAVLCLYFPDGSLVTARGECEGYILEEMRGSGGFGYDPVFY
LPDYGKTMAELPLEIKNKISHRARALEELLRKLKEENRWSTW
>Mature_202_residues
MQRIVIASKNQGKIKEFSALLSSLGFSFVSLLDFPEIGEIPEKGTTFEDNARQKAVTVSNFTGLPALADDSGLVVDALGG
RPGVFSARYAGEPKDDLKNIQKLLKELEGVPWEKRTARFVAVLCLYFPDGSLVTARGECEGYILEEMRGSGGFGYDPVFY
LPDYGKTMAELPLEIKNKISHRARALEELLRKLKEENRWSTW

Specific function: Hydrolyzes non-standard nucleotides such as XTP and dITP/ITP. Might exclude non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions [H]

COG id: COG0127

COG function: function code F; Xanthosine triphosphate pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAM1 NTPase family [H]

Homologues:

Organism=Escherichia coli, GI1789324, Length=196, Percent_Identity=46.9387755102041, Blast_Score=172, Evalue=2e-44,
Organism=Drosophila melanogaster, GI19920712, Length=192, Percent_Identity=32.2916666666667, Blast_Score=73, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002637
- InterPro:   IPR020922 [H]

Pfam domain/function: PF01725 Ham1p_like [H]

EC number: =3.6.1.15 [H]

Molecular weight: Translated: 22496; Mature: 22496

Theoretical pI: Translated: 5.46; Mature: 5.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRIVIASKNQGKIKEFSALLSSLGFSFVSLLDFPEIGEIPEKGTTFEDNARQKAVTVSN
CCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHEEEECC
FTGLPALADDSGLVVDALGGRPGVFSARYAGEPKDDLKNIQKLLKELEGVPWEKRTARFV
CCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHH
AVLCLYFPDGSLVTARGECEGYILEEMRGSGGFGYDPVFYLPDYGKTMAELPLEIKNKIS
HHHHHCCCCCCEEEECCCCCHHHHHHHCCCCCCCCCCEEECCCCCCHHHHCCHHHHHHHH
HRARALEELLRKLKEENRWSTW
HHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MQRIVIASKNQGKIKEFSALLSSLGFSFVSLLDFPEIGEIPEKGTTFEDNARQKAVTVSN
CCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHEEEECC
FTGLPALADDSGLVVDALGGRPGVFSARYAGEPKDDLKNIQKLLKELEGVPWEKRTARFV
CCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHH
AVLCLYFPDGSLVTARGECEGYILEEMRGSGGFGYDPVFYLPDYGKTMAELPLEIKNKIS
HHHHHCCCCCCEEEECCCCCHHHHHHHCCCCCCCCCCEEECCCCCCHHHHCCHHHHHHHH
HRARALEELLRKLKEENRWSTW
HHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA