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The map label for this gene is 78043060

Identifier: 78043060

GI number: 78043060

Start: 228650

End: 229951

Strand: Direct

Name: 78043060

Synonym: CHY_0263

Alternate gene names: NA

Gene position: 228650-229951 (Clockwise)

Preceding gene: 78043707

Following gene: 78044289

Centisome position: 9.52

GC content: 49.08

Gene sequence:

>1302_bases
ATGAATAAAACCGGTCTTTTGTTTTTCCCCGCCTTTGATTGGGCCATATCCCCTACCCATCCGGAAAGGGAAGAACGGCT
GTTATATACCCGGGACCAGATAATGGAGGAAGGGATTTTAGAACTCCCGGGGTTTGTGGAATACAGTGCCCGGCCGGGAA
AAGTAGAAGATGTGGAGAGGGTTCACCTAACAATACCCGATACCCAAAAGGTCGTTACCGATGCCCATTTAATTGCGGCG
GGAAGCTGCATTGAGCTGGCGGAACGGATTTTAGCCGGGGAGGTAAAAAACGGTTTTGCTCTGGTGCGACCGCCGGGACA
CCATGCTACCCGAACGGTTTACGGCAATCGGGGCTTTTGCAATATAAACAATGTCGCTATTACTGTGGATTATCTTCGCT
GGGTAAAAGGGGTTAAAAAGATTGCCATCATCGATACCGATGTCCACCACGGCGATGGGACCCAAGATATTTTTTACCAT
GATCCCGATGTTTTGTTTATTTCTTTGCATCAGGATGGGCGGACCCTGTATCCCGGAACGGGCTTTATAGATGAGGCCGG
AACTCCCAATGCTTACGGTACTACCATAAACTTACCCCTTCCTCCGGGCAGCGGTGATGAGGAAATATTGTATCTTTTGG
AAGAAGCGGTTTTACCCATTTTGGAAGAATTCCAGCCGGAGTTCATTATTAACTCGGCAGGACAGGATAATCATTACTCC
GACCCTTTAGCCCGGATGGCGGTTACCGCCCGGGGTTACGGGCGGATTACCGAGCTAATCAAGCCGGACCTGGCGGTATT
GGAGGGCGGGTATTCCATTGAAGGGGCTTTACCGTATGTAAATTTAGCTATTTTGCTTGCCCTTTACGGGGAAAGTTACG
AAAAGGTTGTAGAACCAAAGGGGCTACCTTTAGAATACCGGGCAAGGCACAAAGATTATGCTAAGAAGCTTGCTGCTGTC
ACGCTGGAGCGCTGGCGGATGCGGGAAGAATTGGCAGAAGAAGAAAAAAGGAAACATAACGGTTACTACTCTTATAACAG
GTCAATATTTTACGATACCGAGGGCTTTCACGAACACCGGGTTACAACCGTAAAGCTTTGCGACCGGTGCCCGGGCTACG
TTGGGTTGAGCAGTTATGCTTACGTTGGGAACCGGGTGGTTTCCGGATTTGCTACAATTGTTATGCCGGGAAGCTGTAAA
GATTGCCGGGAAGAAGCAGAGGCGGTGGCTCTTGAAGCCCTGGCGAAAAAAAATTACGATAAGGTGGCTGTTATTCCCGG
AAAGCAGGTTGTGAAAATTTGA

Upstream 100 bases:

>100_bases
TTTAATGTGGTGCGGGATATGGTGACGGAAAACAAAATATTTATTCTGGAAATAGCGGTGCCGGCCGGGATTTTACGGCC
GGTAGAAGGGAGGATTTTGT

Downstream 100 bases:

>100_bases
AAAATGTTTCCGGAAAAATATTTCCAAAAAGTGTGAAAAAATTTTCTTTTTTTTGCTTCCTTCTGGTTTAATACCCTATG
GAATAATTATTGCTATGAAT

Product: histone deacetylase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 433; Mature: 433

Protein sequence:

>433_residues
MNKTGLLFFPAFDWAISPTHPEREERLLYTRDQIMEEGILELPGFVEYSARPGKVEDVERVHLTIPDTQKVVTDAHLIAA
GSCIELAERILAGEVKNGFALVRPPGHHATRTVYGNRGFCNINNVAITVDYLRWVKGVKKIAIIDTDVHHGDGTQDIFYH
DPDVLFISLHQDGRTLYPGTGFIDEAGTPNAYGTTINLPLPPGSGDEEILYLLEEAVLPILEEFQPEFIINSAGQDNHYS
DPLARMAVTARGYGRITELIKPDLAVLEGGYSIEGALPYVNLAILLALYGESYEKVVEPKGLPLEYRARHKDYAKKLAAV
TLERWRMREELAEEEKRKHNGYYSYNRSIFYDTEGFHEHRVTTVKLCDRCPGYVGLSSYAYVGNRVVSGFATIVMPGSCK
DCREEAEAVALEALAKKNYDKVAVIPGKQVVKI

Sequences:

>Translated_433_residues
MNKTGLLFFPAFDWAISPTHPEREERLLYTRDQIMEEGILELPGFVEYSARPGKVEDVERVHLTIPDTQKVVTDAHLIAA
GSCIELAERILAGEVKNGFALVRPPGHHATRTVYGNRGFCNINNVAITVDYLRWVKGVKKIAIIDTDVHHGDGTQDIFYH
DPDVLFISLHQDGRTLYPGTGFIDEAGTPNAYGTTINLPLPPGSGDEEILYLLEEAVLPILEEFQPEFIINSAGQDNHYS
DPLARMAVTARGYGRITELIKPDLAVLEGGYSIEGALPYVNLAILLALYGESYEKVVEPKGLPLEYRARHKDYAKKLAAV
TLERWRMREELAEEEKRKHNGYYSYNRSIFYDTEGFHEHRVTTVKLCDRCPGYVGLSSYAYVGNRVVSGFATIVMPGSCK
DCREEAEAVALEALAKKNYDKVAVIPGKQVVKI
>Mature_433_residues
MNKTGLLFFPAFDWAISPTHPEREERLLYTRDQIMEEGILELPGFVEYSARPGKVEDVERVHLTIPDTQKVVTDAHLIAA
GSCIELAERILAGEVKNGFALVRPPGHHATRTVYGNRGFCNINNVAITVDYLRWVKGVKKIAIIDTDVHHGDGTQDIFYH
DPDVLFISLHQDGRTLYPGTGFIDEAGTPNAYGTTINLPLPPGSGDEEILYLLEEAVLPILEEFQPEFIINSAGQDNHYS
DPLARMAVTARGYGRITELIKPDLAVLEGGYSIEGALPYVNLAILLALYGESYEKVVEPKGLPLEYRARHKDYAKKLAAV
TLERWRMREELAEEEKRKHNGYYSYNRSIFYDTEGFHEHRVTTVKLCDRCPGYVGLSSYAYVGNRVVSGFATIVMPGSCK
DCREEAEAVALEALAKKNYDKVAVIPGKQVVKI

Specific function: Putative deacetylase [H]

COG id: COG0123

COG function: function code BQ; Deacetylases, including yeast histone deacetylase and acetoin utilization protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the histone deacetylase family [H]

Homologues:

Organism=Homo sapiens, GI30795202, Length=234, Percent_Identity=41.8803418803419, Blast_Score=159, Evalue=4e-39,
Organism=Homo sapiens, GI30795204, Length=234, Percent_Identity=41.8803418803419, Blast_Score=159, Evalue=5e-39,
Organism=Homo sapiens, GI17158039, Length=234, Percent_Identity=41.8803418803419, Blast_Score=159, Evalue=6e-39,
Organism=Homo sapiens, GI169234807, Length=239, Percent_Identity=39.3305439330544, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI148539870, Length=239, Percent_Identity=39.3305439330544, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI153085395, Length=234, Percent_Identity=38.8888888888889, Blast_Score=148, Evalue=1e-35,
Organism=Homo sapiens, GI62750349, Length=201, Percent_Identity=43.2835820895522, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI62750347, Length=201, Percent_Identity=43.2835820895522, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI13128864, Length=288, Percent_Identity=30.9027777777778, Blast_Score=137, Evalue=1e-32,
Organism=Homo sapiens, GI20070354, Length=291, Percent_Identity=32.9896907216495, Blast_Score=136, Evalue=4e-32,
Organism=Homo sapiens, GI226529806, Length=291, Percent_Identity=30.2405498281787, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI13128862, Length=171, Percent_Identity=31.5789473684211, Blast_Score=97, Evalue=4e-20,
Organism=Homo sapiens, GI13128860, Length=171, Percent_Identity=30.4093567251462, Blast_Score=92, Evalue=7e-19,
Organism=Homo sapiens, GI8923769, Length=213, Percent_Identity=28.169014084507, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI293336691, Length=155, Percent_Identity=28.3870967741935, Blast_Score=86, Evalue=6e-17,
Organism=Homo sapiens, GI262073088, Length=160, Percent_Identity=28.75, Blast_Score=86, Evalue=9e-17,
Organism=Homo sapiens, GI209862883, Length=194, Percent_Identity=27.8350515463918, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI262073092, Length=150, Percent_Identity=30, Blast_Score=67, Evalue=4e-11,
Organism=Homo sapiens, GI217272877, Length=194, Percent_Identity=27.8350515463918, Blast_Score=66, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI193209491, Length=230, Percent_Identity=41.7391304347826, Blast_Score=146, Evalue=3e-35,
Organism=Caenorhabditis elegans, GI17540334, Length=292, Percent_Identity=34.2465753424658, Blast_Score=140, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI193206283, Length=298, Percent_Identity=34.2281879194631, Blast_Score=140, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI17540332, Length=291, Percent_Identity=34.3642611683849, Blast_Score=140, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI25154020, Length=213, Percent_Identity=35.6807511737089, Blast_Score=113, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI25154022, Length=224, Percent_Identity=34.375, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17537347, Length=227, Percent_Identity=33.920704845815, Blast_Score=108, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI17534739, Length=205, Percent_Identity=31.219512195122, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17508561, Length=171, Percent_Identity=32.1637426900585, Blast_Score=91, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17561978, Length=170, Percent_Identity=28.8235294117647, Blast_Score=82, Evalue=5e-16,
Organism=Saccharomyces cerevisiae, GI6324307, Length=238, Percent_Identity=36.9747899159664, Blast_Score=142, Evalue=8e-35,
Organism=Saccharomyces cerevisiae, GI6321244, Length=170, Percent_Identity=30.5882352941176, Blast_Score=92, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6323999, Length=201, Percent_Identity=28.3582089552239, Blast_Score=83, Evalue=8e-17,
Organism=Saccharomyces cerevisiae, GI6325325, Length=150, Percent_Identity=32, Blast_Score=79, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24642142, Length=262, Percent_Identity=36.2595419847328, Blast_Score=141, Evalue=7e-34,
Organism=Drosophila melanogaster, GI24642144, Length=262, Percent_Identity=36.2595419847328, Blast_Score=141, Evalue=7e-34,
Organism=Drosophila melanogaster, GI24642146, Length=262, Percent_Identity=36.2595419847328, Blast_Score=141, Evalue=8e-34,
Organism=Drosophila melanogaster, GI281360899, Length=262, Percent_Identity=36.2595419847328, Blast_Score=141, Evalue=9e-34,
Organism=Drosophila melanogaster, GI24641720, Length=211, Percent_Identity=38.8625592417062, Blast_Score=134, Evalue=8e-32,
Organism=Drosophila melanogaster, GI281360801, Length=211, Percent_Identity=38.8625592417062, Blast_Score=134, Evalue=8e-32,
Organism=Drosophila melanogaster, GI281360799, Length=211, Percent_Identity=38.8625592417062, Blast_Score=134, Evalue=8e-32,
Organism=Drosophila melanogaster, GI24644244, Length=171, Percent_Identity=30.9941520467836, Blast_Score=96, Evalue=5e-20,
Organism=Drosophila melanogaster, GI24657891, Length=171, Percent_Identity=31.5789473684211, Blast_Score=94, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000286
- InterPro:   IPR003084 [H]

Pfam domain/function: PF00850 Hist_deacetyl [H]

EC number: NA

Molecular weight: Translated: 48405; Mature: 48405

Theoretical pI: Translated: 5.47; Mature: 5.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKTGLLFFPAFDWAISPTHPEREERLLYTRDQIMEEGILELPGFVEYSARPGKVEDVER
CCCCCEEEEECCCCEECCCCCCHHHHHHHHHHHHHHCCHHHCCCCEEECCCCCCCCCCEE
VHLTIPDTQKVVTDAHLIAAGSCIELAERILAGEVKNGFALVRPPGHHATRTVYGNRGFC
EEEECCCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEECCCCCCCEEEEECCCCEE
NINNVAITVDYLRWVKGVKKIAIIDTDVHHGDGTQDIFYHDPDVLFISLHQDGRTLYPGT
EECCEEEEHHHHHHHHCCCEEEEEECCCCCCCCCCCCEEECCCEEEEEEECCCCEECCCC
GFIDEAGTPNAYGTTINLPLPPGSGDEEILYLLEEAVLPILEEFQPEFIINSAGQDNHYS
CCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCC
DPLARMAVTARGYGRITELIKPDLAVLEGGYSIEGALPYVNLAILLALYGESYEKVVEPK
CHHHHHHHHHCCHHHHHHHHCCCHHEEECCCEECCCCHHHHHHHHHHHHCCCHHHHCCCC
GLPLEYRARHKDYAKKLAAVTLERWRMREELAEEEKRKHNGYYSYNRSIFYDTEGFHEHR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCEEEECCCCCCHHC
VTTVKLCDRCPGYVGLSSYAYVGNRVVSGFATIVMPGSCKDCREEAEAVALEALAKKNYD
CHHHHHHHCCCCCCCCCHHHHHHHHHHHCEEEEEECCCCHHHHHHHHHHHHHHHHHCCCC
KVAVIPGKQVVKI
EEEEECCCCEECC
>Mature Secondary Structure
MNKTGLLFFPAFDWAISPTHPEREERLLYTRDQIMEEGILELPGFVEYSARPGKVEDVER
CCCCCEEEEECCCCEECCCCCCHHHHHHHHHHHHHHCCHHHCCCCEEECCCCCCCCCCEE
VHLTIPDTQKVVTDAHLIAAGSCIELAERILAGEVKNGFALVRPPGHHATRTVYGNRGFC
EEEECCCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEECCCCCCCEEEEECCCCEE
NINNVAITVDYLRWVKGVKKIAIIDTDVHHGDGTQDIFYHDPDVLFISLHQDGRTLYPGT
EECCEEEEHHHHHHHHCCCEEEEEECCCCCCCCCCCCEEECCCEEEEEEECCCCEECCCC
GFIDEAGTPNAYGTTINLPLPPGSGDEEILYLLEEAVLPILEEFQPEFIINSAGQDNHYS
CCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCC
DPLARMAVTARGYGRITELIKPDLAVLEGGYSIEGALPYVNLAILLALYGESYEKVVEPK
CHHHHHHHHHCCHHHHHHHHCCCHHEEECCCEECCCCHHHHHHHHHHHHCCCHHHHCCCC
GLPLEYRARHKDYAKKLAAVTLERWRMREELAEEEKRKHNGYYSYNRSIFYDTEGFHEHR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCEEEECCCCCCHHC
VTTVKLCDRCPGYVGLSSYAYVGNRVVSGFATIVMPGSCKDCREEAEAVALEALAKKNYD
CHHHHHHHCCCCCCCCCHHHHHHHHHHHCEEEEEECCCCHHHHHHHHHHHHHHHHHCCCC
KVAVIPGKQVVKI
EEEEECCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]