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The map label for this gene is kynB [H]

Identifier: 78043051

GI number: 78043051

Start: 616964

End: 617644

Strand: Direct

Name: kynB [H]

Synonym: CHY_0702

Alternate gene names: 78043051

Gene position: 616964-617644 (Clockwise)

Preceding gene: 78044778

Following gene: 78043628

Centisome position: 25.69

GC content: 45.08

Gene sequence:

>681_bases
ATGGCGAAAATAATTGATTTATCCCAGGAAATTTATCAGGGAATGCCTGTTTTTCCCCTGCACCTTACTACGTACATCTT
CCAAAACATAACCCATGAGGAGAGTATTAAAAAAATTGGCTTTCCCTTTGCTACCCGTAACTTACTGATGAACGAACACG
GACCAACCCACTGTGATGCGGTGTACGAGTATAATCCTCAGGGTCCAACCATAGATAAAATGCCATTGGAGTATTTCCTG
GGTCCGGCGATTTGTCTTGATGTATCTCATGTTCCGTACGAGCGCTACATTGAAATTTACGATTTGGAGGGGGCATTACG
GAAACACGGACTTACCATTGAACGTGGAGATATTGTTCTGCTTTATACCGGGCATTATAATCGCAACTACGGCACGGATA
AGTGGCTAACTACCTATTCCGGTTTAAGCTATGCGGCGGCGGAATGGCTGGCCCAAAAGGGAGTAGTAAATATTGGGGTA
GATGCTCCGGCTATTGACCATCCAGACGATCCCAACTACTCCGGTCATGCGGTTTGTGCGAAATACGGCCTTACCAATAC
GGAAAATTTAGCCAATCTTGATAAAGTGGCCGGAAAGCGCTTTTTGTATATTGGTCTACCGTTAAAAATTCGGGATGGTA
CAGGCTCTCCGGTGCGAGCGGTAGCTTTGTTAAACGAATAA

Upstream 100 bases:

>100_bases
TTACCGTTATCCCTTAAGGAGACTGCCCGAGGGGGACTTGCAGCAACCCCTACCGGGAAGGCTTTAGCTAAAAAAATTTT
CGGGCGAAAGGAGGAAAAAA

Downstream 100 bases:

>100_bases
GTTATGAATACAAAAAACATGCAAAATCCCCATTGACAAAAAAATATTAATAAATTATTCTCTAAGTATAGAAATGCATA
GTTGGGCACAAGGGTGTGTC

Product: putative cyclase

Products: NA

Alternate protein names: KFA; N-formylkynurenine formamidase [H]

Number of amino acids: Translated: 226; Mature: 225

Protein sequence:

>226_residues
MAKIIDLSQEIYQGMPVFPLHLTTYIFQNITHEESIKKIGFPFATRNLLMNEHGPTHCDAVYEYNPQGPTIDKMPLEYFL
GPAICLDVSHVPYERYIEIYDLEGALRKHGLTIERGDIVLLYTGHYNRNYGTDKWLTTYSGLSYAAAEWLAQKGVVNIGV
DAPAIDHPDDPNYSGHAVCAKYGLTNTENLANLDKVAGKRFLYIGLPLKIRDGTGSPVRAVALLNE

Sequences:

>Translated_226_residues
MAKIIDLSQEIYQGMPVFPLHLTTYIFQNITHEESIKKIGFPFATRNLLMNEHGPTHCDAVYEYNPQGPTIDKMPLEYFL
GPAICLDVSHVPYERYIEIYDLEGALRKHGLTIERGDIVLLYTGHYNRNYGTDKWLTTYSGLSYAAAEWLAQKGVVNIGV
DAPAIDHPDDPNYSGHAVCAKYGLTNTENLANLDKVAGKRFLYIGLPLKIRDGTGSPVRAVALLNE
>Mature_225_residues
AKIIDLSQEIYQGMPVFPLHLTTYIFQNITHEESIKKIGFPFATRNLLMNEHGPTHCDAVYEYNPQGPTIDKMPLEYFLG
PAICLDVSHVPYERYIEIYDLEGALRKHGLTIERGDIVLLYTGHYNRNYGTDKWLTTYSGLSYAAAEWLAQKGVVNIGVD
APAIDHPDDPNYSGHAVCAKYGLTNTENLANLDKVAGKRFLYIGLPLKIRDGTGSPVRAVALLNE

Specific function: Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine [H]

COG id: COG1878

COG function: function code R; Predicted metal-dependent hydrolase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kynB family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017484
- InterPro:   IPR007325 [H]

Pfam domain/function: PF04199 Cyclase [H]

EC number: =3.5.1.9 [H]

Molecular weight: Translated: 25303; Mature: 25172

Theoretical pI: Translated: 6.02; Mature: 6.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKIIDLSQEIYQGMPVFPLHLTTYIFQNITHEESIKKIGFPFATRNLLMNEHGPTHCDA
CCCCHHCHHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHEECCCCCCCCCE
VYEYNPQGPTIDKMPLEYFLGPAICLDVSHVPYERYIEIYDLEGALRKHGLTIERGDIVL
EEEECCCCCCCCCCCHHHHCCCEEEEECCCCCHHHEEEEEECCHHHHHCCCEEECCCEEE
LYTGHYNRNYGTDKWLTTYSGLSYAAAEWLAQKGVVNIGVDAPAIDHPDDPNYSGHAVCA
EEECCCCCCCCCCCCEEECCCCHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCCEEEE
KYGLTNTENLANLDKVAGKRFLYIGLPLKIRDGTGSPVRAVALLNE
ECCCCCCCHHHHHHHHCCCEEEEEECEEEEECCCCCCEEEEEEECC
>Mature Secondary Structure 
AKIIDLSQEIYQGMPVFPLHLTTYIFQNITHEESIKKIGFPFATRNLLMNEHGPTHCDA
CCCHHCHHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHEECCCCCCCCCE
VYEYNPQGPTIDKMPLEYFLGPAICLDVSHVPYERYIEIYDLEGALRKHGLTIERGDIVL
EEEECCCCCCCCCCCHHHHCCCEEEEECCCCCHHHEEEEEECCHHHHHCCCEEECCCEEE
LYTGHYNRNYGTDKWLTTYSGLSYAAAEWLAQKGVVNIGVDAPAIDHPDDPNYSGHAVCA
EEECCCCCCCCCCCCEEECCCCHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCCEEEE
KYGLTNTENLANLDKVAGKRFLYIGLPLKIRDGTGSPVRAVALLNE
ECCCCCCCHHHHHHHHCCCEEEEEECEEEEECCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA