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The map label for this gene is apeA [H]

Identifier: 78043016

GI number: 78043016

Start: 17854

End: 19245

Strand: Direct

Name: apeA [H]

Synonym: CHY_0023

Alternate gene names: 78043016

Gene position: 17854-19245 (Clockwise)

Preceding gene: 78045219

Following gene: 78045022

Centisome position: 0.74

GC content: 42.46

Gene sequence:

>1392_bases
ATGGATTTAATGTTAAAACGGGAAAATATTTTTTCCAACACAAAAGACCAAAATCCAATCTACCTGTTTAATAGGGAGTA
TCTTGATTTTTTAAGCGGTTGTAAAACCGAACGGAAAGTAGCAAGTTACATAGTGGAAGAGGCTCAAAAACGCGGGTTTA
CGAATCTTGAAGAGGCTTTAAAGGAGGAAAGAACATTAAAACCCGGAGATAAAGTTTATCTTTTCTTTAAAAACAAAGCG
GTGCTTTTAGCGGTAATCGGGGAAAAGCCTTTAAGAGAAGGTTTTAATTTAGTTGCATCTCATTTAGACGTACCGAGGCT
TGATTTAAAACCGCAGCCTCTCTATGAAAAAGATGGCTTTGTTCTGTTAAAAACTCACTACTACGGTGGAATTAAAAAAT
ACCAGTGGGTAACAAGGCCTTTAGCTCTTTGGGGTACGGTAGTTTTGAAAGGCGGAAAAGTTTTAGATATAAAATACGGA
GAAGACGAAAACGAGGGAGTTTTAACGATTACCGATTTACTACCTCATCTTGCTAAAGACCAGATGGAGAAAAAAATAAG
AGAAGCCATTACCGGGGAAGATTTAAATGCGCTTACCGGAAATATTCCGGACCAGGAGGCCAAGGAAAATAAAATTAAAA
CTTATATCCTAAAACTTCTCCACGACCGCTTTGGTATAACTGAAGAAGATTTAATTACTGCGGAACTATCACTGGTACCG
GCAGGTCCAGCCCGGGAAGTGGGTTTGGACCGGAGCATGGTTGGCGGTTTTGGCCAGGACGACCGGGTGTGCGTATTTAC
TTCTTTAAAGGCAATTTTGGAAGTAGAAGCACCGGTAAAAACTGCAATAGCTTTATTTATGGATAGAGAAGAAATCGGCT
CCATGGGCAACACCGGCATGCAAAGTAAGTTTTTAGAAAATGCTATCTTAAAGCTTTTGGTAGCTCAGGGAGAAAAAGAC
GAACTTATGCTTAGGCTTTCGTTAGAAAATGCCCGGGCGCTATCGGCGGATGTGACTGCTGCGGTAGACCCGACCTTTGA
AGGGGTTTTAGAAAAAAATAACGCAGCCCAGATTAATTACGGCATTGTTTTGACCAAATATACCGGTTCCGGCGGCAAGT
ACGGTACCAGCGAAGCATCGGCCGAGTTTATGCGGGAGATAATAGATTTATTTAATCAGGAAGGAATTCGCTGGCAAACC
GGGGAACTGGGCAAAGTGGACCAGGGCGGTGGCGGTACCGTAGCCCAGTTTTTAGCAAATCTCGGGATGGAAGTATTGGA
TGCGGGAGTTGCTTTATTATCGATGCACTCTCCCTTTGAAGTAGCCGGTAAAGCCGATATTTATGAAGCTTACCGGGCGT
ATAAAGCATTTTTGAGTGGTGGTAAGTCGTAG

Upstream 100 bases:

>100_bases
ACTTTTTAAGTTTGGTTCAAAATTCTCTGGTTTTAAATTACTTCTTTACCTTAGTTAAAGATGGCATTTCAACCTTTACA
GGAATAAAGGAGGCTAAGCT

Downstream 100 bases:

>100_bases
GAATTTAAAAGTGGTAAGTCGTAGGTGTTAAGTGGTCGGTCAATAATAAGGGTAACCCAAGAGGTAGGGGCAACTCCTGT
TGCCCATTGTGATGTGTGAA

Product: putative aminopeptidase 1

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 463; Mature: 463

Protein sequence:

>463_residues
MDLMLKRENIFSNTKDQNPIYLFNREYLDFLSGCKTERKVASYIVEEAQKRGFTNLEEALKEERTLKPGDKVYLFFKNKA
VLLAVIGEKPLREGFNLVASHLDVPRLDLKPQPLYEKDGFVLLKTHYYGGIKKYQWVTRPLALWGTVVLKGGKVLDIKYG
EDENEGVLTITDLLPHLAKDQMEKKIREAITGEDLNALTGNIPDQEAKENKIKTYILKLLHDRFGITEEDLITAELSLVP
AGPAREVGLDRSMVGGFGQDDRVCVFTSLKAILEVEAPVKTAIALFMDREEIGSMGNTGMQSKFLENAILKLLVAQGEKD
ELMLRLSLENARALSADVTAAVDPTFEGVLEKNNAAQINYGIVLTKYTGSGGKYGTSEASAEFMREIIDLFNQEGIRWQT
GELGKVDQGGGGTVAQFLANLGMEVLDAGVALLSMHSPFEVAGKADIYEAYRAYKAFLSGGKS

Sequences:

>Translated_463_residues
MDLMLKRENIFSNTKDQNPIYLFNREYLDFLSGCKTERKVASYIVEEAQKRGFTNLEEALKEERTLKPGDKVYLFFKNKA
VLLAVIGEKPLREGFNLVASHLDVPRLDLKPQPLYEKDGFVLLKTHYYGGIKKYQWVTRPLALWGTVVLKGGKVLDIKYG
EDENEGVLTITDLLPHLAKDQMEKKIREAITGEDLNALTGNIPDQEAKENKIKTYILKLLHDRFGITEEDLITAELSLVP
AGPAREVGLDRSMVGGFGQDDRVCVFTSLKAILEVEAPVKTAIALFMDREEIGSMGNTGMQSKFLENAILKLLVAQGEKD
ELMLRLSLENARALSADVTAAVDPTFEGVLEKNNAAQINYGIVLTKYTGSGGKYGTSEASAEFMREIIDLFNQEGIRWQT
GELGKVDQGGGGTVAQFLANLGMEVLDAGVALLSMHSPFEVAGKADIYEAYRAYKAFLSGGKS
>Mature_463_residues
MDLMLKRENIFSNTKDQNPIYLFNREYLDFLSGCKTERKVASYIVEEAQKRGFTNLEEALKEERTLKPGDKVYLFFKNKA
VLLAVIGEKPLREGFNLVASHLDVPRLDLKPQPLYEKDGFVLLKTHYYGGIKKYQWVTRPLALWGTVVLKGGKVLDIKYG
EDENEGVLTITDLLPHLAKDQMEKKIREAITGEDLNALTGNIPDQEAKENKIKTYILKLLHDRFGITEEDLITAELSLVP
AGPAREVGLDRSMVGGFGQDDRVCVFTSLKAILEVEAPVKTAIALFMDREEIGSMGNTGMQSKFLENAILKLLVAQGEKD
ELMLRLSLENARALSADVTAAVDPTFEGVLEKNNAAQINYGIVLTKYTGSGGKYGTSEASAEFMREIIDLFNQEGIRWQT
GELGKVDQGGGGTVAQFLANLGMEVLDAGVALLSMHSPFEVAGKADIYEAYRAYKAFLSGGKS

Specific function: Unknown

COG id: COG1362

COG function: function code E; Aspartyl aminopeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M18 family [H]

Homologues:

Organism=Homo sapiens, GI156416028, Length=455, Percent_Identity=25.2747252747253, Blast_Score=97, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17552916, Length=455, Percent_Identity=25.7142857142857, Blast_Score=114, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6322746, Length=462, Percent_Identity=25.5411255411255, Blast_Score=102, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6321905, Length=477, Percent_Identity=23.8993710691824, Blast_Score=77, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022983
- InterPro:   IPR001948 [H]

Pfam domain/function: PF02127 Peptidase_M18 [H]

EC number: NA

Molecular weight: Translated: 51296; Mature: 51296

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLMLKRENIFSNTKDQNPIYLFNREYLDFLSGCKTERKVASYIVEEAQKRGFTNLEEAL
CCCEEECHHHHCCCCCCCCEEEECHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHH
KEERTLKPGDKVYLFFKNKAVLLAVIGEKPLREGFNLVASHLDVPRLDLKPQPLYEKDGF
HHHCCCCCCCEEEEEEECCEEEEEEECCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCE
VLLKTHYYGGIKKYQWVTRPLALWGTVVLKGGKVLDIKYGEDENEGVLTITDLLPHLAKD
EEEEECCCCCCHHHHHHHHHHHHHHHHEECCCEEEEEEECCCCCCCEEEHHHHHHHHHHH
QMEKKIREAITGEDLNALTGNIPDQEAKENKIKTYILKLLHDRFGITEEDLITAELSLVP
HHHHHHHHHHCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHEEEEEEEEEC
AGPAREVGLDRSMVGGFGQDDRVCVFTSLKAILEVEAPVKTAIALFMDREEIGSMGNTGM
CCCCHHHCCCHHHHCCCCCCCCEEHHHHHHHHHHCCCHHHHHHHHHHCHHHHCCCCCCCH
QSKFLENAILKLLVAQGEKDELMLRLSLENARALSADVTAAVDPTFEGVLEKNNAAQINY
HHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHCCCCEEECCCHHHHHHCCCCCCEEEE
GIVLTKYTGSGGKYGTSEASAEFMREIIDLFNQEGIRWQTGELGKVDQGGGGTVAQFLAN
EEEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCHHHHHHHH
LGMEVLDAGVALLSMHSPFEVAGKADIYEAYRAYKAFLSGGKS
CCHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MDLMLKRENIFSNTKDQNPIYLFNREYLDFLSGCKTERKVASYIVEEAQKRGFTNLEEAL
CCCEEECHHHHCCCCCCCCEEEECHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHH
KEERTLKPGDKVYLFFKNKAVLLAVIGEKPLREGFNLVASHLDVPRLDLKPQPLYEKDGF
HHHCCCCCCCEEEEEEECCEEEEEEECCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCE
VLLKTHYYGGIKKYQWVTRPLALWGTVVLKGGKVLDIKYGEDENEGVLTITDLLPHLAKD
EEEEECCCCCCHHHHHHHHHHHHHHHHEECCCEEEEEEECCCCCCCEEEHHHHHHHHHHH
QMEKKIREAITGEDLNALTGNIPDQEAKENKIKTYILKLLHDRFGITEEDLITAELSLVP
HHHHHHHHHHCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHEEEEEEEEEC
AGPAREVGLDRSMVGGFGQDDRVCVFTSLKAILEVEAPVKTAIALFMDREEIGSMGNTGM
CCCCHHHCCCHHHHCCCCCCCCEEHHHHHHHHHHCCCHHHHHHHHHHCHHHHCCCCCCCH
QSKFLENAILKLLVAQGEKDELMLRLSLENARALSADVTAAVDPTFEGVLEKNNAAQINY
HHHHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHCCCCEEECCCHHHHHHCCCCCCEEEE
GIVLTKYTGSGGKYGTSEASAEFMREIIDLFNQEGIRWQTGELGKVDQGGGGTVAQFLAN
EEEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCHHHHHHHH
LGMEVLDAGVALLSMHSPFEVAGKADIYEAYRAYKAFLSGGKS
CCHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11466286 [H]