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The map label for this gene is alr

Identifier: 78042901

GI number: 78042901

Start: 579627

End: 580733

Strand: Direct

Name: alr

Synonym: CHY_0667

Alternate gene names: 78042901

Gene position: 579627-580733 (Clockwise)

Preceding gene: 78043495

Following gene: 78044606

Centisome position: 24.14

GC content: 46.07

Gene sequence:

>1107_bases
ATGCGTCCGGTATGGGCAGAGGTTAACCTGGAAAATATTCGGCATAATTTCCGGGAAGTAAAAAGACTTGCTCGGCAGGC
GGAGGCGATGCCGGTAATAAAGGCCAATGCTTACGGTCACGGAGCGGTGGAAGTGGCAAAAGCTTTAATTGCCGAGGGGG
CTAAACGGTTTGCGGTGGCCATTCTTGATGAAGGAATAAAGTTGAGAGAAGCGGGGATAGATGCACCGGTTCTTATTTTG
GGTTACACTCCTCCCGAAGAGGTGGAAAAGCTTTTATTTTATAACCTGACTCCTACTCTTCACCACCGGGAATTAGCTTT
AGCGTATCAGGAAAGACTTGAGAGGCTTAAGAAAACCCTTTTCTATCATCTAAAAATTGATACGGGAATGGGGAGAATCG
GGTTCTGGTATGAAGAACTCGAAAAGATTGAGGAAGTATTAAAATTAAAAAATTTAGAAGCGGAAGGAGTTTATACCCAT
TTTGCCCGGGCGGATGAGCAAGATTTAAGTTTTTCCAAGCTGCAAATAGAGAGGTTTAACATTGTGTTAAAACACTTAAA
AGCCAAAGGGATTGAGGTAAAATACCGCCATGCTGCCAACAGTGCTGCAATAATGAGGCTTCCCGAAGCTCACTACGATT
TGGTGCGACCGGGGATTATGCTGTACGGCGAGTATCCCTCCAGGGATGTACCCCGGGAACTTGCCCATTTAAAGCCTGCT
TTAACCTTAAAAGCCAGGGTTTCTCAGGTGAAAAAAGTACCGGCAGGCTTTACGGTGAGTTACGGTAGCACGTACGTAAC
CTCCAAAGCTACCCTGATTGTTTCGCTGCCGTTAGGTTATGCCGATGGTTATTTTCGCCGCCTTTCCAATCGAGGGGTGG
TTTTGATAAACGGCAAACGCTGGTCCATAGCCGGTCGGGTTTGCATGGATCAATTGATGGTAGCGGTGGATGAAACCGAA
AGGGTAAATCCCGGGGATGAGGCTGTTCTCTTGGGAAAGCAGGGAGAAGAAACGATTACCGCTATGGAAATGGCAGACCT
GGTGGGAACTATAAATTATGAAATTTTGACCAATATAAGTTACCGGGTTCCGCGAATTTATGTGTAA

Upstream 100 bases:

>100_bases
TGGAAGAAATCCTCGGTTAGAGGTAAAAGGGGTGGATAATTCCACCCCTTTGCTATATCATTAACATTAAAAAAGAAAAG
TTTTCTGGTAGGTGGAAAAA

Downstream 100 bases:

>100_bases
AATTCATTTATAAAAAATATTTATGGATTTTGAGGCTGCAAGCCTCTTTTTTTATGTATTTGAAAAAAAAAGTCGAACAT
GGTATAATTTTATCGAAGCA

Product: alanine racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 368; Mature: 368

Protein sequence:

>368_residues
MRPVWAEVNLENIRHNFREVKRLARQAEAMPVIKANAYGHGAVEVAKALIAEGAKRFAVAILDEGIKLREAGIDAPVLIL
GYTPPEEVEKLLFYNLTPTLHHRELALAYQERLERLKKTLFYHLKIDTGMGRIGFWYEELEKIEEVLKLKNLEAEGVYTH
FARADEQDLSFSKLQIERFNIVLKHLKAKGIEVKYRHAANSAAIMRLPEAHYDLVRPGIMLYGEYPSRDVPRELAHLKPA
LTLKARVSQVKKVPAGFTVSYGSTYVTSKATLIVSLPLGYADGYFRRLSNRGVVLINGKRWSIAGRVCMDQLMVAVDETE
RVNPGDEAVLLGKQGEETITAMEMADLVGTINYEILTNISYRVPRIYV

Sequences:

>Translated_368_residues
MRPVWAEVNLENIRHNFREVKRLARQAEAMPVIKANAYGHGAVEVAKALIAEGAKRFAVAILDEGIKLREAGIDAPVLIL
GYTPPEEVEKLLFYNLTPTLHHRELALAYQERLERLKKTLFYHLKIDTGMGRIGFWYEELEKIEEVLKLKNLEAEGVYTH
FARADEQDLSFSKLQIERFNIVLKHLKAKGIEVKYRHAANSAAIMRLPEAHYDLVRPGIMLYGEYPSRDVPRELAHLKPA
LTLKARVSQVKKVPAGFTVSYGSTYVTSKATLIVSLPLGYADGYFRRLSNRGVVLINGKRWSIAGRVCMDQLMVAVDETE
RVNPGDEAVLLGKQGEETITAMEMADLVGTINYEILTNISYRVPRIYV
>Mature_368_residues
MRPVWAEVNLENIRHNFREVKRLARQAEAMPVIKANAYGHGAVEVAKALIAEGAKRFAVAILDEGIKLREAGIDAPVLIL
GYTPPEEVEKLLFYNLTPTLHHRELALAYQERLERLKKTLFYHLKIDTGMGRIGFWYEELEKIEEVLKLKNLEAEGVYTH
FARADEQDLSFSKLQIERFNIVLKHLKAKGIEVKYRHAANSAAIMRLPEAHYDLVRPGIMLYGEYPSRDVPRELAHLKPA
LTLKARVSQVKKVPAGFTVSYGSTYVTSKATLIVSLPLGYADGYFRRLSNRGVVLINGKRWSIAGRVCMDQLMVAVDETE
RVNPGDEAVLLGKQGEETITAMEMADLVGTINYEILTNISYRVPRIYV

Specific function: Provides the D-alanine required for cell wall biosynthesis

COG id: COG0787

COG function: function code M; Alanine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alanine racemase family

Homologues:

Organism=Escherichia coli, GI1787439, Length=372, Percent_Identity=34.1397849462366, Blast_Score=181, Evalue=1e-46,
Organism=Escherichia coli, GI1790487, Length=367, Percent_Identity=32.1525885558583, Blast_Score=179, Evalue=3e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ALR_CARHZ (Q9F8I0)

Other databases:

- EMBL:   CP000141
- EMBL:   AF244653
- RefSeq:   YP_359522.1
- ProteinModelPortal:   Q9F8I0
- STRING:   Q9F8I0
- GeneID:   3727039
- GenomeReviews:   CP000141_GR
- KEGG:   chy:CHY_0667
- NMPDR:   fig|246194.3.peg.483
- TIGR:   CHY_0667
- eggNOG:   COG0787
- HOGENOM:   HBG712172
- OMA:   NDENIAM
- BioCyc:   CHYD246194:CHY_0667-MONOMER
- HAMAP:   MF_01201
- InterPro:   IPR000821
- InterPro:   IPR009006
- InterPro:   IPR011079
- InterPro:   IPR001608
- InterPro:   IPR020622
- Gene3D:   G3DSA:2.40.37.10
- PRINTS:   PR00992
- TIGRFAMs:   TIGR00492

Pfam domain/function: PF00842 Ala_racemase_C; PF01168 Ala_racemase_N; SSF50621 Racem_decarbox_C

EC number: =5.1.1.1

Molecular weight: Translated: 41633; Mature: 41633

Theoretical pI: Translated: 9.31; Mature: 9.31

Prosite motif: PS00395 ALANINE_RACEMASE

Important sites: ACT_SITE 34-34 ACT_SITE 261-261

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPVWAEVNLENIRHNFREVKRLARQAEAMPVIKANAYGHGAVEVAKALIAEGAKRFAVA
CCCEEEECCHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHCCHHHEEEE
ILDEGIKLREAGIDAPVLILGYTPPEEVEKLLFYNLTPTLHHRELALAYQERLERLKKTL
EHHCCCEEECCCCCCCEEEEECCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHE
FYHLKIDTGMGRIGFWYEELEKIEEVLKLKNLEAEGVYTHFARADEQDLSFSKLQIERFN
EEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCHHHHHHHHHH
IVLKHLKAKGIEVKYRHAANSAAIMRLPEAHYDLVRPGIMLYGEYPSRDVPRELAHLKPA
HHHHHHHCCCCEEEEEECCCCEEEEECCHHHHHHHCCCEEEEECCCCCCHHHHHHHCCHH
LTLKARVSQVKKVPAGFTVSYGSTYVTSKATLIVSLPLGYADGYFRRLSNRGVVLINGKR
HHHHHHHHHHHHCCCCEEEECCCEEEECCEEEEEEECCCCCCHHHHHHCCCCEEEECCCE
WSIAGRVCMDQLMVAVDETERVNPGDEAVLLGKQGEETITAMEMADLVGTINYEILTNIS
EEHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCEEEECCC
YRVPRIYV
CCCCEEEC
>Mature Secondary Structure
MRPVWAEVNLENIRHNFREVKRLARQAEAMPVIKANAYGHGAVEVAKALIAEGAKRFAVA
CCCEEEECCHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHCCHHHEEEE
ILDEGIKLREAGIDAPVLILGYTPPEEVEKLLFYNLTPTLHHRELALAYQERLERLKKTL
EHHCCCEEECCCCCCCEEEEECCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHE
FYHLKIDTGMGRIGFWYEELEKIEEVLKLKNLEAEGVYTHFARADEQDLSFSKLQIERFN
EEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCHHHHHHHHHH
IVLKHLKAKGIEVKYRHAANSAAIMRLPEAHYDLVRPGIMLYGEYPSRDVPRELAHLKPA
HHHHHHHCCCCEEEEEECCCCEEEEECCHHHHHHHCCCEEEEECCCCCCHHHHHHHCCHH
LTLKARVSQVKKVPAGFTVSYGSTYVTSKATLIVSLPLGYADGYFRRLSNRGVVLINGKR
HHHHHHHHHHHHCCCCEEEECCCEEEECCEEEEEEECCCCCCHHHHHHCCCCEEEECCCE
WSIAGRVCMDQLMVAVDETERVNPGDEAVLLGKQGEETITAMEMADLVGTINYEILTNIS
EEHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCEEEECCC
YRVPRIYV
CCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA