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The map label for this gene is fur [H]

Identifier: 78042705

GI number: 78042705

Start: 564311

End: 564733

Strand: Direct

Name: fur [H]

Synonym: CHY_0651

Alternate gene names: 78042705

Gene position: 564311-564733 (Clockwise)

Preceding gene: 78045154

Following gene: 78043378

Centisome position: 23.5

GC content: 47.75

Gene sequence:

>423_bases
ATGAATGTAAGAGAAGCATATAAAATTTTACGGGATAAGGGCATAAAGATTACACCGCAGCGGCAGGCGCTTTTAGAGCT
TTTTGCCGATGAAAAAAGCTATACCGCCCGGGAGATTGCCGAAAAATTGCGCCGGCATTACCCTGGTTTTAGTTTCGATA
CCGTTTACCGTAACTTAAAGCTTTACTGCCGGTGCGGGATTTTAACCGAGACCATGGCGCCGGACGGGATAGCCCGCTTT
TCCTTAAATACCGGACAGCACCGCCATTATTTCACCTGCCTTGCCTGCGGGGAGAAAGTGGCCCTGGAATCGTGTCCTAT
TGAAGAAAATAAATTTAACCTTCCGGGAAAAGTGGGGACGATAACGTATCACCGGATTGAACTTTTTGGAAAGTGTGCAG
CCTGCGAGGAGGGGAAAAAGTGA

Upstream 100 bases:

>100_bases
GCATTAAAGGCGAAGGTATTTAAAATCCCCTTGACTCGGTAAATTTACAGGTATAGATTAATTTTTAGATAGGAATAATT
ACGATGTAGGTGGGAATACG

Downstream 100 bases:

>100_bases
AGCGAGTACTTGCGCTGGTTTTAGTTTTTACTTTATTTGTACTTTCGGGCTGTTCCAATGCCCGGACGGCTTCTACAACC
GATAGCGGTAAGCCTTTGAT

Product: FUR family transcriptional regulator

Products: NA

Alternate protein names: Ferric uptake regulator [H]

Number of amino acids: Translated: 140; Mature: 140

Protein sequence:

>140_residues
MNVREAYKILRDKGIKITPQRQALLELFADEKSYTAREIAEKLRRHYPGFSFDTVYRNLKLYCRCGILTETMAPDGIARF
SLNTGQHRHYFTCLACGEKVALESCPIEENKFNLPGKVGTITYHRIELFGKCAACEEGKK

Sequences:

>Translated_140_residues
MNVREAYKILRDKGIKITPQRQALLELFADEKSYTAREIAEKLRRHYPGFSFDTVYRNLKLYCRCGILTETMAPDGIARF
SLNTGQHRHYFTCLACGEKVALESCPIEENKFNLPGKVGTITYHRIELFGKCAACEEGKK
>Mature_140_residues
MNVREAYKILRDKGIKITPQRQALLELFADEKSYTAREIAEKLRRHYPGFSFDTVYRNLKLYCRCGILTETMAPDGIARF
SLNTGQHRHYFTCLACGEKVALESCPIEENKFNLPGKVGTITYHRIELFGKCAACEEGKK

Specific function: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

None

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 16056; Mature: 16056

Theoretical pI: Translated: 8.86; Mature: 8.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
5.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVREAYKILRDKGIKITPQRQALLELFADEKSYTAREIAEKLRRHYPGFSFDTVYRNLK
CCHHHHHHHHHHCCCEECCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHH
LYCRCGILTETMAPDGIARFSLNTGQHRHYFTCLACGEKVALESCPIEENKFNLPGKVGT
HEEECCCHHCCCCCCCEEEEECCCCCCCCEEEEEECCCHHHHCCCCCCCCCCCCCCCEEE
ITYHRIELFGKCAACEEGKK
EEHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MNVREAYKILRDKGIKITPQRQALLELFADEKSYTAREIAEKLRRHYPGFSFDTVYRNLK
CCHHHHHHHHHHCCCEECCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHH
LYCRCGILTETMAPDGIARFSLNTGQHRHYFTCLACGEKVALESCPIEENKFNLPGKVGT
HEEECCCHHCCCCCCCEEEEECCCCCCCCEEEEEECCCHHHHCCCCCCCCCCCCCCCEEE
ITYHRIELFGKCAACEEGKK
EEHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8764488 [H]