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The map label for this gene is adcA [H]

Identifier: 78043378

GI number: 78043378

Start: 564730

End: 565611

Strand: Direct

Name: adcA [H]

Synonym: CHY_0652

Alternate gene names: 78043378

Gene position: 564730-565611 (Clockwise)

Preceding gene: 78042705

Following gene: 78045197

Centisome position: 23.52

GC content: 42.29

Gene sequence:

>882_bases
GTGAAGCGAGTACTTGCGCTGGTTTTAGTTTTTACTTTATTTGTACTTTCGGGCTGTTCCAATGCCCGGACGGCTTCTAC
AACCGATAGCGGTAAGCCTTTGATTGTTACTTCAATTTATCCCTATGGTGAGCTTGCCCGGGAGATTGCCGGGGATAAAG
CTGAGGTTACGGTTTTAGCCCCTCCTGGAGCCGATGCCCATGATTTTGAACCAAAACCTTCCGACCTTTTTACCCTGAGG
AAGGCCGATTTAATCATCTTAAATGGTGGGGGCTTAGAGCCCTGGGCCGGAAAGATAATCAAGCTTTTAGGAAAAGATAA
GGTTATTGAAGCGGAAAAAATTTTGGAAGGCAAAGTAAAAAAAGACGATCCCCATTACTGGCTATCTTTGATATTTGCCC
GCAAAATAGCCGAAGCTATTAAGGATAATTTAGTAACGCTGGATCCGGGAAATAAAAGCTACTATGAGGAAAATTACCGC
AAACTTGCCGATAAACTTTATGAGCTGCATTTGGCGATGGTGGATCTTACCTCGGACCTAAAAACCCGCAAGATTTTTAC
CCTGCACCGGGCCTTTGGTTATTTTGCAGCCGATTACGGTTTACAGGAAATTTCCCTGATGTCCGGAAAGGAAGCGGAAG
CAACCGTTGGCGATATTGAAAAGTTTATGAAAGAATTTTCGGCGGAAGGTTGTGAATACGTATTTTTTGACCCGGTTTTT
GGTAAAAAGGTTGCGGAAAAAGTTTCTGAAAACTACAGGGTGAAGTTTATGCCCCTTTATACTTTAGAAGGAGTTGATGA
AACCCTAAAAGGTAAAAGCTATTTAGAATTAATGCAGGAGAATATTGAAACTTTGCGCCTTGTTTTAGGAGGAGATGATT
AA

Upstream 100 bases:

>100_bases
TTGAAGAAAATAAATTTAACCTTCCGGGAAAAGTGGGGACGATAACGTATCACCGGATTGAACTTTTTGGAAAGTGTGCA
GCCTGCGAGGAGGGGAAAAA

Downstream 100 bases:

>100_bases
ATTTGGGGCTAGAAGTTAAAAACCTCTCTGTAAATTACGGCGGTGAGCCGGTATTAGAGGATATAAATTTTTCATTAAAG
GAAGGGGATTTTCTTTTGGT

Product: ABC transporter substrate-binding protein

Products: Zn (II) [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 293; Mature: 293

Protein sequence:

>293_residues
MKRVLALVLVFTLFVLSGCSNARTASTTDSGKPLIVTSIYPYGELAREIAGDKAEVTVLAPPGADAHDFEPKPSDLFTLR
KADLIILNGGGLEPWAGKIIKLLGKDKVIEAEKILEGKVKKDDPHYWLSLIFARKIAEAIKDNLVTLDPGNKSYYEENYR
KLADKLYELHLAMVDLTSDLKTRKIFTLHRAFGYFAADYGLQEISLMSGKEAEATVGDIEKFMKEFSAEGCEYVFFDPVF
GKKVAEKVSENYRVKFMPLYTLEGVDETLKGKSYLELMQENIETLRLVLGGDD

Sequences:

>Translated_293_residues
MKRVLALVLVFTLFVLSGCSNARTASTTDSGKPLIVTSIYPYGELAREIAGDKAEVTVLAPPGADAHDFEPKPSDLFTLR
KADLIILNGGGLEPWAGKIIKLLGKDKVIEAEKILEGKVKKDDPHYWLSLIFARKIAEAIKDNLVTLDPGNKSYYEENYR
KLADKLYELHLAMVDLTSDLKTRKIFTLHRAFGYFAADYGLQEISLMSGKEAEATVGDIEKFMKEFSAEGCEYVFFDPVF
GKKVAEKVSENYRVKFMPLYTLEGVDETLKGKSYLELMQENIETLRLVLGGDD
>Mature_293_residues
MKRVLALVLVFTLFVLSGCSNARTASTTDSGKPLIVTSIYPYGELAREIAGDKAEVTVLAPPGADAHDFEPKPSDLFTLR
KADLIILNGGGLEPWAGKIIKLLGKDKVIEAEKILEGKVKKDDPHYWLSLIFARKIAEAIKDNLVTLDPGNKSYYEENYR
KLADKLYELHLAMVDLTSDLKTRKIFTLHRAFGYFAADYGLQEISLMSGKEAEATVGDIEKFMKEFSAEGCEYVFFDPVF
GKKVAEKVSENYRVKFMPLYTLEGVDETLKGKSYLELMQENIETLRLVLGGDD

Specific function: Part of the high-affinity ABC transporter complex AdcABC involved in zinc import (Probable) [H]

COG id: COG0803

COG function: function code P; ABC-type metal ion transport system, periplasmic component/surface adhesin

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 9 family [H]

Homologues:

Organism=Escherichia coli, GI87081990, Length=291, Percent_Identity=27.1477663230241, Blast_Score=91, Evalue=7e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006127
- InterPro:   IPR006129
- InterPro:   IPR006128 [H]

Pfam domain/function: PF01297 SBP_bac_9 [H]

EC number: NA

Molecular weight: Translated: 32753; Mature: 32753

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRVLALVLVFTLFVLSGCSNARTASTTDSGKPLIVTSIYPYGELAREIAGDKAEVTVLA
CHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHCCCCCEEEEEE
PPGADAHDFEPKPSDLFTLRKADLIILNGGGLEPWAGKIIKLLGKDKVIEAEKILEGKVK
CCCCCCCCCCCCCCCEEEEEECCEEEEECCCCCHHHHHHHHHHCCCCCCCHHHHHCCCCC
KDDPHYWLSLIFARKIAEAIKDNLVTLDPGNKSYYEENYRKLADKLYELHLAMVDLTSDL
CCCHHHHHHHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCH
KTRKIFTLHRAFGYFAADYGLQEISLMSGKEAEATVGDIEKFMKEFSAEGCEYVFFDPVF
HHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCEEEECCHH
GKKVAEKVSENYRVKFMPLYTLEGVDETLKGKSYLELMQENIETLRLVLGGDD
HHHHHHHHCCCCEEEEEEEEEECCCCHHHCCHHHHHHHHHHHHHEEEEECCCC
>Mature Secondary Structure
MKRVLALVLVFTLFVLSGCSNARTASTTDSGKPLIVTSIYPYGELAREIAGDKAEVTVLA
CHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHCCCCCEEEEEE
PPGADAHDFEPKPSDLFTLRKADLIILNGGGLEPWAGKIIKLLGKDKVIEAEKILEGKVK
CCCCCCCCCCCCCCCEEEEEECCEEEEECCCCCHHHHHHHHHHCCCCCCCHHHHHCCCCC
KDDPHYWLSLIFARKIAEAIKDNLVTLDPGNKSYYEENYRKLADKLYELHLAMVDLTSDL
CCCHHHHHHHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCH
KTRKIFTLHRAFGYFAADYGLQEISLMSGKEAEATVGDIEKFMKEFSAEGCEYVFFDPVF
HHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCEEEECCHH
GKKVAEKVSENYRVKFMPLYTLEGVDETLKGKSYLELMQENIETLRLVLGGDD
HHHHHHHHCCCCEEEEEEEEEECCCCHHHCCHHHHHHHHHHHHHEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Zn (II) [Periplasm]; H2O; ATP [C]

Specific reaction: Zn (II) [Periplasm] + H2O + ATP = Zn (II) [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9274031; 9384377; 9811636 [H]