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The map label for this gene is rbsK [H]

Identifier: 77465743

GI number: 77465743

Start: 863419

End: 864366

Strand: Direct

Name: rbsK [H]

Synonym: RSP_3738

Alternate gene names: 77465743

Gene position: 863419-864366 (Clockwise)

Preceding gene: 77465742

Following gene: 77465744

Centisome position: 91.56

GC content: 70.68

Gene sequence:

>948_bases
ATGACCGCATCGAAACCCGGCCGCATCGCGGTCGTCGGCTCCAACATGGTCGATCTGGTGACCTACATCACCCGGATGCC
CGCGCCCGGCGAGACGATCGAGGCGCCCGACTTCGAGATCGGCTGCGGCGGCAAGGGCGCCAATCAGGCGGTGGCCGCCG
CAAAGCTCGGCAGCGCGGTCAGCATGGTGACGAAGGTCGGCGACGACATCTTCGGCGAGAACACCCGCCGCAACCTCGCC
CAGCACGGCATCGACATCCGCCATGTGGAGACGGTGGCGGGCAAGTCCTCGGGCGTGGCGCCGATCTTCGTCGAGGCGTC
GGGCGAGAATTCGATCCTGATCGTGAAGGGCGCGAATGCCGACCTTTTGCCCGCCGATGTGGATACGGCCGAAGAGACGC
TGCGCGCGGCCGACCTGATCCTGATGCAGATGGAGGTCCCGCGCGAGACGGTGATCCATACCGTGCGGCGGGCGGCGGAA
TGGGGCGTGCGCACCATCCTGAACCCCGCCCCGGCCGCGGCCGACCTGAATGTGGATGACCTGCGCGACCTGAGCTTCCT
CGTGCCGAACGAGAGCGAGCTTGCGCTGATCTCGGGCCTGCCCACCGGCAGCGAGGAGGAGATCGCGGCCGCCGCCCTGA
GCCTGATCGAGCGCGGCATCGGCACGGTGATCGTGACGCTGGGCGGGCGCGGCGCCCGGCTGGTGACCCGCGCGGGCGTG
GTGCCCATCGCCCCGGTCCGGGTGACGCCCGTCGACACGACCGGCGCGGGCGATGCCTTCATCGGCGCCTTCGCCCATTT
CCTCGCCGCGACCGGCGAGGTGGAGGGCGCGCTGGCCCACGCCGCGCGCTATGCCGCCCATTCCGTGACGGGGCGCGGCA
CCCAGAAATCCTACGCCACGCCGGAGGCCTTCGAGGCCTTCTGCCGCGCGCTCCCCCCATCCGCATGA

Upstream 100 bases:

>100_bases
GGGCGAAAGCGCCCGCTTCCCGGTGACGCTGGGCTGGCTCGGGCCGACCGAGGTGGCCGCGGCGCGCGCCGACATCGACA
CCATGCGAAAGGGCTGAGCC

Downstream 100 bases:

>100_bases
AGGCCCACGCCATGCCCGACAGCCACCCCCGCAACCCCGGCACGCCCTTCGCCCCCGACTGGTTCGAGGAGATGCAGGTG
AACCGCACCGCGGCCGAGCG

Product: carbohydrate kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 315; Mature: 314

Protein sequence:

>315_residues
MTASKPGRIAVVGSNMVDLVTYITRMPAPGETIEAPDFEIGCGGKGANQAVAAAKLGSAVSMVTKVGDDIFGENTRRNLA
QHGIDIRHVETVAGKSSGVAPIFVEASGENSILIVKGANADLLPADVDTAEETLRAADLILMQMEVPRETVIHTVRRAAE
WGVRTILNPAPAAADLNVDDLRDLSFLVPNESELALISGLPTGSEEEIAAAALSLIERGIGTVIVTLGGRGARLVTRAGV
VPIAPVRVTPVDTTGAGDAFIGAFAHFLAATGEVEGALAHAARYAAHSVTGRGTQKSYATPEAFEAFCRALPPSA

Sequences:

>Translated_315_residues
MTASKPGRIAVVGSNMVDLVTYITRMPAPGETIEAPDFEIGCGGKGANQAVAAAKLGSAVSMVTKVGDDIFGENTRRNLA
QHGIDIRHVETVAGKSSGVAPIFVEASGENSILIVKGANADLLPADVDTAEETLRAADLILMQMEVPRETVIHTVRRAAE
WGVRTILNPAPAAADLNVDDLRDLSFLVPNESELALISGLPTGSEEEIAAAALSLIERGIGTVIVTLGGRGARLVTRAGV
VPIAPVRVTPVDTTGAGDAFIGAFAHFLAATGEVEGALAHAARYAAHSVTGRGTQKSYATPEAFEAFCRALPPSA
>Mature_314_residues
TASKPGRIAVVGSNMVDLVTYITRMPAPGETIEAPDFEIGCGGKGANQAVAAAKLGSAVSMVTKVGDDIFGENTRRNLAQ
HGIDIRHVETVAGKSSGVAPIFVEASGENSILIVKGANADLLPADVDTAEETLRAADLILMQMEVPRETVIHTVRRAAEW
GVRTILNPAPAAADLNVDDLRDLSFLVPNESELALISGLPTGSEEEIAAAALSLIERGIGTVIVTLGGRGARLVTRAGVV
PIAPVRVTPVDTTGAGDAFIGAFAHFLAATGEVEGALAHAARYAAHSVTGRGTQKSYATPEAFEAFCRALPPSA

Specific function: Ribose metabolism; first step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=290, Percent_Identity=41.0344827586207, Blast_Score=193, Evalue=1e-49,
Organism=Escherichia coli, GI1790193, Length=302, Percent_Identity=38.7417218543046, Blast_Score=172, Evalue=3e-44,
Organism=Escherichia coli, GI87082343, Length=285, Percent_Identity=30.5263157894737, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1789775, Length=294, Percent_Identity=28.9115646258503, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI1788491, Length=270, Percent_Identity=24.0740740740741, Blast_Score=69, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17532905, Length=298, Percent_Identity=36.241610738255, Blast_Score=182, Evalue=1e-46,
Organism=Saccharomyces cerevisiae, GI6319884, Length=321, Percent_Identity=31.1526479750779, Blast_Score=118, Evalue=2e-27,
Organism=Drosophila melanogaster, GI20128807, Length=300, Percent_Identity=43, Blast_Score=192, Evalue=2e-49,
Organism=Drosophila melanogaster, GI24583886, Length=312, Percent_Identity=31.0897435897436, Blast_Score=140, Evalue=1e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR011877
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.15 [H]

Molecular weight: Translated: 32522; Mature: 32391

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTASKPGRIAVVGSNMVDLVTYITRMPAPGETIEAPDFEIGCGGKGANQAVAAAKLGSAV
CCCCCCCEEEEECCCHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHH
SMVTKVGDDIFGENTRRNLAQHGIDIRHVETVAGKSSGVAPIFVEASGENSILIVKGANA
HHHHHHHHHHCCCCHHHHHHHHCCCEEEHHHHCCCCCCCCEEEEEECCCCCEEEEECCCC
DLLPADVDTAEETLRAADLILMQMEVPRETVIHTVRRAAEWGVRTILNPAPAAADLNVDD
CCCCCCCCHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHH
LRDLSFLVPNESELALISGLPTGSEEEIAAAALSLIERGIGTVIVTLGGRGARLVTRAGV
HCCCEEECCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEECCC
VPIAPVRVTPVDTTGAGDAFIGAFAHFLAATGEVEGALAHAARYAAHSVTGRGTQKSYAT
CEECCEEEECCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCC
PEAFEAFCRALPPSA
HHHHHHHHHHCCCCC
>Mature Secondary Structure 
TASKPGRIAVVGSNMVDLVTYITRMPAPGETIEAPDFEIGCGGKGANQAVAAAKLGSAV
CCCCCCEEEEECCCHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHH
SMVTKVGDDIFGENTRRNLAQHGIDIRHVETVAGKSSGVAPIFVEASGENSILIVKGANA
HHHHHHHHHHCCCCHHHHHHHHCCCEEEHHHHCCCCCCCCEEEEEECCCCCEEEEECCCC
DLLPADVDTAEETLRAADLILMQMEVPRETVIHTVRRAAEWGVRTILNPAPAAADLNVDD
CCCCCCCCHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHH
LRDLSFLVPNESELALISGLPTGSEEEIAAAALSLIERGIGTVIVTLGGRGARLVTRAGV
HCCCEEECCCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEECCC
VPIAPVRVTPVDTTGAGDAFIGAFAHFLAATGEVEGALAHAARYAAHSVTGRGTQKSYAT
CEECCEEEECCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCC
PEAFEAFCRALPPSA
HHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]