Click here to switch to the map view.

The map label for this gene is tlyC [H]

Identifier: 77465598

GI number: 77465598

Start: 690311

End: 691258

Strand: Reverse

Name: tlyC [H]

Synonym: RSP_3597

Alternate gene names: 77465598

Gene position: 691258-690311 (Counterclockwise)

Preceding gene: 77465599

Following gene: 77465597

Centisome position: 73.3

GC content: 68.67

Gene sequence:

>948_bases
ATGGACAGTAGCAGCGACGGGTCTATGGCAGCGCAGAGCGCGCCCGACCAGACGGAAGACGACCAGGCGGAGCCTGGACC
GAAAGGCCTTTTCGGCCGCCTTTTCAGCGCCTTCTCGCCCGCCGAGGCCGGAGGCGGTGCCCTGTCCCCGCAGGACCGGG
CCTTCGCCATCGCGCAGAGCAGCCTGACCCTTCCCGGCATTGCCAACCTGCGCCGCCTCCGGGTGGACGATGTGGCGATT
CCCAAGGTCGAGATCGTGGCCGTGCCGGTGGACATCGGCAAGGAGGATCTGGTGGCGGTGTTCCGCGAGCACGGATTCTC
GCGCCTGCCGGTCTACCGCGAGACGCTCGACCAGCCGCTGGGCCTCGTGCTGCTCAAGGATCTGGCGCTTCAGCACGGGT
TCAACGGCAACGGCAGCTTCGATCTGAAGACGCTGCTGCGGCCGCTCCTTTATGCGCCGCCCTCGATGCCGATCGGCGTC
CTTCTGCAGAAGATGCAGCGCGAGCGGGTGCATATGGCGCTCGTCATCGACGAATATGGCGGGGTCGACGGGCTCGTCAC
CATCGAGGACCTGATCGAAACCGTGATCGGCGAGATCGAGGACGAGCATGACGAGGTCGAGGGCCCGCTCTGGACGCTCG
AGAAACCCGGCGTCTACATGGCGCAGTCGCGCACGCCGCTCGACGAGTTCGAGGCCGAGATCGGCCTGCGCCTCCGCCGC
GAGGAGGAGGACGAGGAGATCGACACGCTGGGCGGGCTCGTCTTCCTGCGCACCGGCCGCGTGCCCGTCCGCGGCGAGAT
CGTCCCGCACGAGAGCGGCGCCGAATTCGAGGTGATCGACGCCGACGCGCGCAAGATCAAGCGGCTGCGCGTCCGTCTTC
CGGGCGCCGTCGCCGCGCCCGTGGGGGGGCGCGCGCTGCCGGCCGAACAGCCCCTTCATTCTGGCTGA

Upstream 100 bases:

>100_bases
CCTGATGGAGGCGACCGAGACAAGGATACTTGCGGGGCTGGGGGTGCCCGACCCATATTGATCCGGCGCCGGATCTGGCG
CGGCCATTCGGAAAGGACAG

Downstream 100 bases:

>100_bases
AATATCCTCGGGGGGTGCGGGGGGCAGACAGCCCCCCGTGGCCCGACCCGTCCCGGCGCACCCGCCGCTCTCCCCGGTTC
GGACCTCGTTCACAGCCTCT

Product: CorC/Hlyc family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 315; Mature: 315

Protein sequence:

>315_residues
MDSSSDGSMAAQSAPDQTEDDQAEPGPKGLFGRLFSAFSPAEAGGGALSPQDRAFAIAQSSLTLPGIANLRRLRVDDVAI
PKVEIVAVPVDIGKEDLVAVFREHGFSRLPVYRETLDQPLGLVLLKDLALQHGFNGNGSFDLKTLLRPLLYAPPSMPIGV
LLQKMQRERVHMALVIDEYGGVDGLVTIEDLIETVIGEIEDEHDEVEGPLWTLEKPGVYMAQSRTPLDEFEAEIGLRLRR
EEEDEEIDTLGGLVFLRTGRVPVRGEIVPHESGAEFEVIDADARKIKRLRVRLPGAVAAPVGGRALPAEQPLHSG

Sequences:

>Translated_315_residues
MDSSSDGSMAAQSAPDQTEDDQAEPGPKGLFGRLFSAFSPAEAGGGALSPQDRAFAIAQSSLTLPGIANLRRLRVDDVAI
PKVEIVAVPVDIGKEDLVAVFREHGFSRLPVYRETLDQPLGLVLLKDLALQHGFNGNGSFDLKTLLRPLLYAPPSMPIGV
LLQKMQRERVHMALVIDEYGGVDGLVTIEDLIETVIGEIEDEHDEVEGPLWTLEKPGVYMAQSRTPLDEFEAEIGLRLRR
EEEDEEIDTLGGLVFLRTGRVPVRGEIVPHESGAEFEVIDADARKIKRLRVRLPGAVAAPVGGRALPAEQPLHSG
>Mature_315_residues
MDSSSDGSMAAQSAPDQTEDDQAEPGPKGLFGRLFSAFSPAEAGGGALSPQDRAFAIAQSSLTLPGIANLRRLRVDDVAI
PKVEIVAVPVDIGKEDLVAVFREHGFSRLPVYRETLDQPLGLVLLKDLALQHGFNGNGSFDLKTLLRPLLYAPPSMPIGV
LLQKMQRERVHMALVIDEYGGVDGLVTIEDLIETVIGEIEDEHDEVEGPLWTLEKPGVYMAQSRTPLDEFEAEIGLRLRR
EEEDEEIDTLGGLVFLRTGRVPVRGEIVPHESGAEFEVIDADARKIKRLRVRLPGAVAAPVGGRALPAEQPLHSG

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=213, Percent_Identity=27.2300469483568, Blast_Score=92, Evalue=5e-19,
Organism=Escherichia coli, GI1786879, Length=237, Percent_Identity=33.3333333333333, Blast_Score=117, Evalue=7e-28,
Organism=Escherichia coli, GI145693175, Length=141, Percent_Identity=27.6595744680851, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI87082033, Length=203, Percent_Identity=27.5862068965517, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC [H]

EC number: NA

Molecular weight: Translated: 34189; Mature: 34189

Theoretical pI: Translated: 4.43; Mature: 4.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSSSDGSMAAQSAPDQTEDDQAEPGPKGLFGRLFSAFSPAEAGGGALSPQDRAFAIAQS
CCCCCCCCCHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECC
SLTLPGIANLRRLRVDDVAIPKVEIVAVPVDIGKEDLVAVFREHGFSRLPVYRETLDQPL
CCCCCCHHHHHHEEECCCCCCCEEEEEEECCCCHHHHHHHHHHCCCCCCCHHHHHHCCCH
GLVLLKDLALQHGFNGNGSFDLKTLLRPLLYAPPSMPIGVLLQKMQRERVHMALVIDEYG
HHHHHHHHHHHCCCCCCCCEEHHHHHHHHHCCCCCCCHHHHHHHHHHHHEEEEEEEECCC
GVDGLVTIEDLIETVIGEIEDEHDEVEGPLWTLEKPGVYMAQSRTPLDEFEAEIGLRLRR
CCCCEEEHHHHHHHHHHHHCCHHHHCCCCEEEECCCCEEEECCCCCHHHHHHHHCCCCCC
EEEDEEIDTLGGLVFLRTGRVPVRGEIVPHESGAEFEVIDADARKIKRLRVRLPGAVAAP
CCCHHHHHHHCCEEEEEECCCCCCEEEECCCCCCCEEEECCHHHHHHHHHHCCCCCEECC
VGGRALPAEQPLHSG
CCCCCCCCCCCCCCC
>Mature Secondary Structure
MDSSSDGSMAAQSAPDQTEDDQAEPGPKGLFGRLFSAFSPAEAGGGALSPQDRAFAIAQS
CCCCCCCCCHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECC
SLTLPGIANLRRLRVDDVAIPKVEIVAVPVDIGKEDLVAVFREHGFSRLPVYRETLDQPL
CCCCCCHHHHHHEEECCCCCCCEEEEEEECCCCHHHHHHHHHHCCCCCCCHHHHHHCCCH
GLVLLKDLALQHGFNGNGSFDLKTLLRPLLYAPPSMPIGVLLQKMQRERVHMALVIDEYG
HHHHHHHHHHHCCCCCCCCEEHHHHHHHHHCCCCCCCHHHHHHHHHHHHEEEEEEEECCC
GVDGLVTIEDLIETVIGEIEDEHDEVEGPLWTLEKPGVYMAQSRTPLDEFEAEIGLRLRR
CCCCEEEHHHHHHHHHHHHCCHHHHCCCCEEEECCCCEEEECCCCCHHHHHHHHCCCCCC
EEEDEEIDTLGGLVFLRTGRVPVRGEIVPHESGAEFEVIDADARKIKRLRVRLPGAVAAP
CCCHHHHHHHCCEEEEEECCCCCCEEEECCCCCCCEEEECCHHHHHHHHHHCCCCCEECC
VGGRALPAEQPLHSG
CCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA